194-59-2 | 7H-Dibenzo[c,g]carbazole

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$9.00	$6.00
5g	98%	in stock	$28.00	$19.00
10g	98%	in stock	$49.00	$34.00
25g	98%	in stock	$112.00	$78.00

Description

• Catalog Number: AB70131
• Chemical Name: 7H-Dibenzo[c,g]carbazole
• CAS Number: 194-59-2
• Molecular Formula: C20H13N
• Molecular Weight: 267.3239
• MDL Number: MFCD00215941
• SMILES: c1ccc2c(c1)ccc1c2c2c([nH]1)ccc1c2cccc1
• NSC Number: 87519

Computed Properties

• Complexity: 355
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Donor Count: 1
• XLogP3: 5.9

Literature

• Sustained induction of cytochrome P4501A1 in human hepatoma cells by co-exposure to benzo[a]pyrene and 7H-dibenzo[c,g]carbazole underlies the synergistic effects on DNA adduct formation.

  Toxicology and applied pharmacology 20130815

• Polycyclic aromatic hydrocarbons: 15 Listings - benz[a]anthracene, benzo[b]fluoranthene, benzo[j]fluoranthene, benzo[k]fluoranthene, benzo[a]pyrene, dibenz[a,h]acridine, dibenz[a,j]acridine, dibenz[a,h]anthracene, 7H-dibenzo[c,g]carbazole, dibenzo[a,e]pyrene, dibenzo[a,h]pyrene, dibenzo[a,i]pyrene, dibenzo[a,l]pyrene, indeno[1,2,3-cd]pyrene, 5-methylchrysene.

  Report on carcinogens : carcinogen profiles 20110101

• 7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes.

  Carcinogenesis 20070601

• Impact of Cyp1a2 or Ahr gene knockout in mice: implications for biomonitoring studies.

  Toxicology letters 20060410

• DNA adduct formation by 7H-dibenzo[c,g]carbazole and its tissue- and organ-specific derivatives in Chinese hamster V79 cell lines stably expressing cytochrome P450 enzymes.

  Environmental and molecular mutagenesis 20040101

• A metabolic activation mechanism of 7H-dibenzo[c,g]carbazole via o-quinone. Part 2: covalent adducts of 7H-dibenzo[c,g]carbazole-3,4-dione with nucleic acid bases and nucleosides.

  Chemical research in toxicology 20020701

• Mutagenicity of 7H-dibenzo[c,g]carbazole and its tissue specific derivatives in genetically engineered Chinese hamster V79 cell lines stably expressing cytochrome P450.

  Mutation research 20020527

• Comparison of Ha-ras mutational spectra of N-methyldibenzo[c,g]carbazole and 7H-dibenzo[c,g]carbazole-induced mouse skin tumors.

  Molecular carcinogenesis 20011001

• The effects of a binary mixture of benzo(a)pyrene and 7H-dibenzo(c,g)carbazole on lung tumors and K-ras oncogene mutations in strain A/J mice.

  Experimental lung research 20010101

• Induction of micronuclei and sister chromatid exchanges by polycyclic and N-heterocyclic aromatic hydrocarbons in cultured human lymphocytes.

  Environmental and molecular mutagenesis 19950101