19741-14-1 | 4-[N-(2,4-Diamino-6-pteridinylmethyl)-n-methylamino]benzoic acid

Packsize	Purity	Availability	Price	Discounted Price
5mg	90%	in stock	$54.00	$38.00
25mg	90%	in stock	$139.00	$97.00
100mg	90%	in stock	$142.00	$99.00
250mg	90%	in stock	$283.00	$198.00
1g	90%	in stock	$579.00	$406.00
5g	90%	in stock	$1,587.00	$1,111.00

Description

• Catalog Number: AD30761
• Chemical Name: 4-[N-(2,4-Diamino-6-pteridinylmethyl)-n-methylamino]benzoic acid
• CAS Number: 19741-14-1
• Molecular Formula: C15H15N7O2
• Molecular Weight: 325.3253
• MDL Number: MFCD00075774
• SMILES: Nc1nc(N)c2c(n1)ncc(n2)CN(c1ccc(cc1)C(=O)O)C
• NSC Number: 131463

Computed Properties

• Complexity: 444
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 24
• Hydrogen Bond Acceptor Count: 9
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 4
• XLogP3: -1.1

Literature

• Simple and sensitive HPLC method for the fluorometric determination of methotrexate and its major metabolites in human plasma by post-column photochemical reaction.

  Biomedical chromatography : BMC 20120101

• The influence of 7-OH methotrexate metabolite on clinical relevance of methotrexate determination.

  Clinical laboratory 20110101

• Commentary.

  Clinical chemistry 20101201

• Commentary.

  Clinical chemistry 20101201

• Determination of the chiral and achiral related substances of methotrexate by cyclodextrin-modified micellar electrokinetic chromatography.

  Electrophoresis 20040801

• Identification of highly potent and selective inhibitors of Toxoplasma gondii dihydrofolate reductase.

  Antimicrobial agents and chemotherapy 19930901

• Pneumocystis carinii dihydrofolate reductase used to screen potential antipneumocystis drugs.

  Antimicrobial agents and chemotherapy 19910701

• Inhibition of Pneumocystis dihydrofolate reductase by analogs of pyrimethamine, methotrexate and trimetrexate.

  The Journal of protozoology 19910101