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Anti-fibrotic effects of L-2-oxothiazolidine-4-carboxylic acid via modulation of nuclear factor erythroid 2-related factor 2 in rats.
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L-2-Oxothiazolidine-4-carboxylic acid or α-lipoic acid attenuates airway remodeling: involvement of nuclear factor-κB (NF-κB), nuclear factor erythroid 2p45-related factor-2 (Nrf2), and hypoxia-inducible factor (HIF).
International journal of molecular sciences 20120101
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Chronic alcohol ingestion exacerbates lung epithelial barrier dysfunction in HIV-1 transgenic rats.
Alcoholism, clinical and experimental research 20111001
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L-2-oxothiazolidine-4-carboxylate influence on age- and heat exposure-dependent redox changes in rat's blood plasma.
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Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin.
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Transport via SLC5A8 (SMCT1) is obligatory for 2-oxothiazolidine-4-carboxylate to enhance glutathione production in retinal pigment epithelial cells.
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Cigarette smoke-induced changes to alveolar macrophage phenotype and function are improved by treatment with procysteine.
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In vivo and in vitro assessment of the role of glutathione antioxidant system in anthracycline-induced cardiotoxicity.
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Cytotoxicity of dentine bonding agents on human pulp cells is related to intracellular glutathione levels.
International endodontic journal 20101201
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International endodontic journal 20100501
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Glutathione modulators reverse the pro-tumour effect of growth factors enhancing WiDr cell response to chemotherapeutic agents.
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Procysteine increases alcohol-depleted glutathione stores in rat plantaris following a period of abstinence.
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Glutathione modulation reverses the growth-promoting effect of growth factors, improving the 5-fluorouracil antitumour response in WiDr colon cancer cells.
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The protective effects of N-Acetl-cysteine, oxo-thiazolidine-carboxylate, acetaminophen and their combinations against sulfur mustard cytotoxicity on human skin fibroblast cell line (HF2FF).
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Pulmonary exposure to diesel exhaust particles promotes cerebral microvessel thrombosis: protective effect of a cysteine prodrug l-2-oxothiazolidine-4-carboxylic acid.
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Pro-oxidant-mediated hepatic fibrosis and effects of antioxidant intervention in murine dietary steatohepatitis.
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L-2-Oxothiazolidine-4-carboxylate reverses glutathione oxidation and delays fatigue of skeletal muscle in vitro.
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Normal saline induces oxidative stress in peritoneal mesothelial cells.
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Increased metal tolerance in Salix by nicotinamide and nicotinic acid.
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Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration.
American journal of physiology. Heart and circulatory physiology 20080601
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A double-blind placebo-controlled study to evaluate the safety and efficacy of L-2-oxothiazolidine-4-carboxylic acid in the treatment of patients with acute respiratory distress syndrome.
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Localization and thiol dependancy of endogenous nitro compounds-mediating urethral photo-relaxation.
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Differentiation of Sclerotinia minor depends on thiol redox state and oxidative stress.
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Cytotoxicity of formaldehyde on human osteoblastic cells is related to intracellular glutathione levels.
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The ameliorative effect of cysteine prodrug L-2-oxothiazolidine-4-carboxylic acid on cisplatin-induced nephrotoxicity in rats.
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Cytomodulation of interleukin-2 effect by L-2-oxothiazolidine-4-carboxylate on human malignant melanoma.
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Protective role of L-2-oxothiazolidine-4-carboxylic acid in cisplatin-induced renal injury.
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An antioxidant modulates expression of receptor activator of NF-kappaB in asthma.
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Regulation of nicotine-induced cyclooxygenase-2 protein expression in human gingival fibroblasts.
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Effects of glutathione supplementation during peritoneal dialysis.
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A prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, regulates vascular permeability by reducing vascular endothelial growth factor expression in asthma.
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Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes.
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L-2-oxothiazolidine-4-carboxylic acid reduces in vitro cytotoxicity of glucose degradation products.
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Regulation of interleukin-6 expression by arecoline in human buccal mucosal fibroblasts is related to intracellular glutathione levels.
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Preventive effect of antioxidants in MPTP-induced mouse model of Parkinson's disease.
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Bovine 5-oxo-L-prolinase: simple assay method, purification, cDNA cloning, and detection of mRNA in the coronary artery.
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Pyroglutamyl aminopeptidase I, as a drug metabolizing enzyme, recognizes xenobiotic substrates containing L-2-oxothiazolidine-4-carboxylic acid.
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Oxothiazolidine carboxylate provides protection against hepatocellular injury seen after porta hepatis occlusion (Pringle maneuver) under hypovolemic conditions.
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Antidiabetic effect of a prodrug of cysteine, L-2-oxothiazolidine-4-carboxylic acid, through CD38 dimerization and internalization.
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Cellular redox state and endothelial dysfunction in mildly hyperhomocysteinemic cystathionine beta-synthase-deficient mice.
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L-2-oxothiazolidine-4-carboxylate: an agent that modulates lipopolysaccharide-induced peritonitis in rats.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20020101
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Promoting glutathione synthesis after spinal cord trauma decreases secondary damage and promotes retention of function.
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Effects of L-2-oxothiazolidine-4-carboxylate on the cytotoxic activity and toxicity of cyclophosphamide in mice bearing B16F10 melanoma liver metastases.
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Protective effects of L-2-oxothiazolidine-4-carboxylate treatment on cyclophosphamide-induced cystitis in rats.
The Journal of urology 19970501
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L-2-oxothiazolidine-4-carboxylic acid inhibits human immunodeficiency virus type 1 replication in mononuclear phagocytes and lymphocytes.
Clinical and diagnostic laboratory immunology 19970501
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Experimental nephrology 19960101
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AIDS research and human retroviruses 19940801
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