198904-31-3 | Atazanavir

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$33.00	$23.00
1g	95%	in stock	$57.00	$40.00
5g	95%	in stock	$116.00	$81.00
25g	95%	in stock	$305.00	$213.00

Description

• Catalog Number: AD29877
• Chemical Name: Atazanavir
• CAS Number: 198904-31-3
• Molecular Formula: C38H52N6O7
• Molecular Weight: 704.8554800000002
• MDL Number: MFCD08435966
• SMILES: COC(=O)N[C@@H](C(C)(C)C)C(=O)NN(Cc1ccc(cc1)c1ccccn1)C[C@@H]([C@H](Cc1ccccc1)NC(=O)[C@H](C(C)(C)C)NC(=O)OC)O

Computed Properties

• Complexity: 1110
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 51
• Hydrogen Bond Acceptor Count: 9
• Hydrogen Bond Donor Count: 5
• Rotatable Bond Count: 18
• XLogP3: 5.6

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  The Annals of pharmacotherapy 20110601

• Management of HIV infection in treatment-naive patients: a review of the most current recommendations.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110601

• Prevention of peptic ulcers with esomeprazole in patients at risk of ulcer development treated with low-dose acetylsalicylic acid: a randomised, controlled trial (OBERON).

  Heart (British Cardiac Society) 20110515

• Atazanavir concentration in hair is the strongest predictor of outcomes on antiretroviral therapy.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110515

• [Persistence in focus. Atazanavir proves itself anew in long-term therapy].

  MMW Fortschritte der Medizin 20110505

• HIV-1 integrase inhibitor resistance and its clinical implications.

  The Journal of infectious diseases 20110501

• [Characteristics of antiretroviral drugs].

  Enfermedades infecciosas y microbiologia clinica 20110501

• CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope.

  PLoS pathogens 20110501

• Human immunodeficiency virus therapeutics and pharmacogenomics.

  Indian journal of human genetics 20110501

• Gradient RP-HPLC method for the determination of potential impurities in atazanavir sulfate.

  Journal of pharmaceutical and biomedical analysis 20110428

• The use of atazanavir in HIV-infected patients with liver cirrhosis: lack of hepatotoxicity and no significant changes in bilirubin values or model for end-stage liver disease score.

  AIDS (London, England) 20110424

• Atazanavir pharmacokinetics with and without tenofovir during pregnancy.

  Journal of acquired immune deficiency syndromes (1999) 20110415

• Pentacycloundecane-based inhibitors of wild-type C-South African HIV-protease.

  Bioorganic & medicinal chemistry letters 20110415

• Atazanavir plus ritonavir or efavirenz as part of a 3-drug regimen for initial treatment of HIV-1.

  Annals of internal medicine 20110405

• Proper laboratory notebook practices: protecting your intellectual property.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110401

• Comparison of the influence of four classes of HIV antiretrovirals on adipogenic differentiation: the minimal effect of raltegravir and atazanavir.

  Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20110401

• Cost-effectiveness of atazanavir/ritonavir compared with lopinavir/ritonavir in treatment-naïve human immunodeficiency virus-1 patients in Sweden.

  Scandinavian journal of infectious diseases 20110401

• Tenofovir discontinuation could predispose to urolithiasis in atazanavir-treated patients.

  The Journal of infection 20110401

• Pharmacokinetic interaction of vicriviroc with other antiretroviral agents: results from a series of fixed-sequence and parallel-group clinical trials.

  Clinical pharmacokinetics 20110401

• The International Interlaboratory Quality Control Program for Measurement of Antiretroviral Drugs in Plasma: a global proficiency testing program.

  Therapeutic drug monitoring 20110401

• Within-patient atazanavir trough concentration monitoring in HIV-1-infected patients.

  Journal of pharmacy practice 20110401

• A HPLC-MS method for the simultaneous quantification of fourteen antiretroviral agents in peripheral blood mononuclear cell of HIV infected patients optimized using medium corpuscular volume evaluation.

  Journal of pharmaceutical and biomedical analysis 20110325

• Analyses of nanoformulated antiretroviral drug charge, size, shape and content for uptake, drug release and antiviral activities in human monocyte-derived macrophages.

  Journal of controlled release : official journal of the Controlled Release Society 20110310

• Effect of low-dose omeprazole (20 mg daily) on the pharmacokinetics of multiple-dose atazanavir with ritonavir in healthy subjects.

  Journal of clinical pharmacology 20110301

• Atazanavir metabolism according to CYP3A5 status: an in vitro-in vivo assessment.

  Drug metabolism and disposition: the biological fate of chemicals 20110301

• CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolism.

  Drug metabolism and disposition: the biological fate of chemicals 20110301

• Detrimental effect of atazanavir plasma concentrations on total serum bilirubin levels in the presence of UGT1A1 polymorphisms.

  Journal of acquired immune deficiency syndromes (1999) 20110301

• Hepatic safety and lack of antiretroviral interactions with buprenorphine/naloxone in HIV-infected opioid-dependent patients.

  Journal of acquired immune deficiency syndromes (1999) 20110301

• FDA notifications. FDA approves new atazanavir labeling.

  AIDS alert 20110301

• Intestinal enzymatic metabolism of drugs.

  The Journal of pharmacy and pharmacology 20110301

• Glyceroneogenesis is inhibited through HIV protease inhibitor-induced inflammation in human subcutaneous but not visceral adipose tissue.

  Journal of lipid research 20110201

• The bilirubin-increasing drug atazanavir improves endothelial function in patients with type 2 diabetes mellitus.

  Arteriosclerosis, thrombosis, and vascular biology 20110201

• Comparative gender analysis of the efficacy and safety of atazanavir/ritonavir and lopinavir/ritonavir at 96 weeks in the CASTLE study.

  The Journal of antimicrobial chemotherapy 20110201

• Approach to dyslipidemia, lipodystrophy, and cardiovascular risk in patients with HIV infection.

  Current atherosclerosis reports 20110201

• Boosted protease inhibitors and the electrocardiographic measures of QT and PR durations.

  AIDS (London, England) 20110128

• Design and synthesis of potent HIV-1 protease inhibitors incorporating hexahydrofuropyranol-derived high affinity P(2) ligands: structure-activity studies and biological evaluation.

  Journal of medicinal chemistry 20110127

• Managing the atazanavir-tacrolimus drug interaction in a renal transplant recipient.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110115

• Association of pharmacogenetic markers with premature discontinuation of first-line anti-HIV therapy: an observational cohort study.

  The Journal of infectious diseases 20110115

• The toxicogenetics of antiretroviral therapy: the evil inside.

  Current medicinal chemistry 20110101

• HIV-infected adolescents: relationship between atazanavir plasma levels and bilirubin concentrations.

  The Journal of adolescent health : official publication of the Society for Adolescent Medicine 20110101

• Long-term safety from the raltegravir clinical development program.

  Current HIV research 20110101

• Renal disease associated with antiretroviral therapy in the treatment of HIV.

  Nephron. Clinical practice 20110101

• Understanding diabetes in patients with HIV/AIDS.

  Diabetology & metabolic syndrome 20110101

• Safety, Tolerability, and Efficacy of Second-Line Generic Protease Inhibitor Containing HAART after First-Line Failure among South Indian HIV-Infected Patients.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20110101

• Cost effectiveness of atazanavir-ritonavir versus lopinavir-ritonavir in treatment-naïve human immunodeficiency virus-infected patients in the United States.

  Journal of medical economics 20110101

• Human immunodeficiency virus type 2 in two Saudi families.

  Annals of Saudi medicine 20110101

• Chronic interstitial nephritis in an HIV type-1-infected patient receiving ritonavir-boosted atazanavir.

  Antiviral therapy 20110101

• The L76V mutation in HIV-1 protease is potentially associated with hypersusceptibility to protease inhibitors Atazanavir and Saquinavir: is there a clinical advantage?

  AIDS research and therapy 20110101

• Development of Buffalo Hump in the course of antiretroviral therapy including raltegravir and unboosted atazanavir: a case report and review of the literature.

  Journal of medical case reports 20110101

• HIV-1 infected patients with suppressed plasma viremia on treatment have pro-inflammatory HDL.

  Lipids in health and disease 20110101

• Management of HIV-1 associated hepatitis in patients with acquired immunodeficiency syndrome: role of a successful control of viral replication.

  AIDS research and therapy 20110101

• Prevalence of potential drug-drug interactions involving antiretroviral drugs in a large Kenyan cohort.

  PloS one 20110101

• Antiretroviral therapy outcomes in HIV-infected children after adjusting protease inhibitor dosing during tuberculosis treatment.

  PloS one 20110101

• Time for gender mainstreaming in editorial policies.

  Journal of the International AIDS Society 20110101

• Drug efficacy by direct and adjusted indirect comparison to placebo: An illustration by Mycobacterium avium complex prophylaxis in HIV.

  AIDS research and therapy 20110101

• 'Dynamic range' of inferred phenotypic HIV drug resistance values in clinical practice.

  PloS one 20110101

• Genome-wide analysis of primary CD4+ and CD8+ T cell transcriptomes shows evidence for a network of enriched pathways associated with HIV disease.

  Retrovirology 20110101

• Acute toxicity of second generation HIV protease-inhibitors in combination with radiotherapy: a retrospective case series.

  Radiation oncology (London, England) 20110101

• In vitro and in vivo cleavage of HIV-1 RNA by new SOFA-HDV ribozymes and their potential to inhibit viral replication.

  RNA biology 20110101

• High efficacy of lopinavir/r-based second-line antiretroviral treatment after 24 months of follow up at ESTHER/Calmette Hospital in Phnom Penh, Cambodia.

  Journal of the International AIDS Society 20110101

• The effect of atazanavir/ritonavir on the pharmacokinetics of an oral contraceptive containing ethinyl estradiol and norgestimate in healthy women.

  Antiviral therapy 20110101

• Interaction between antiretroviral drugs and acenocoumarol.

  Antiviral therapy 20110101

• Machine learning on normalized protein sequences.

  BMC research notes 20110101

• Comparison of intima-media thickness and ophthalmic artery resistance index for assessing subclinical atherosclerosis in HIV-1-infected patients.

  Cardiovascular ultrasound 20110101

• Changes in lipid profiles after switching to a protease inhibitor-containing cART--unfavourable effect of fosamprenavir in obese patients.

  European journal of medical research 20110101

• Open-label randomized multicenter selection study of once daily antiretroviral treatment regimen comparing ritonavir-boosted atazanavir to efavirenz with fixed-dose abacavir and lamivudine.

  Internal medicine (Tokyo, Japan) 20110101

• The rainbow cohort: 96 week follow-up of saquinavir-containing regimens in previously antiretroviral therapy (ART)-naive and pre-treated but protease inhibitor (PI)-naive HIV-infected patients.

  European journal of medical research 20110101

• Antiretroviral Therapy for HIV-2 Infection: Recommendations for Management in Low-Resource Settings.

  AIDS research and treatment 20110101

• Utilization patterns and projected demand of antiretroviral drugs in low- and middle-income countries.

  AIDS research and treatment 20110101

• Protease Inhibitor Resistance Is Uncommon in HIV-1 Subtype C Infected Patients on Failing Second-Line Lopinavir/r-Containing Antiretroviral Therapy in South Africa.

  AIDS research and treatment 20110101

• Ixabepilone as monotherapy or in combination with capecitabine for the treatment of advanced breast cancer.

  Breast cancer : basic and clinical research 20110101

• Nevirapine versus atazanavir/ritonavir, each combined with tenofovir disoproxil fumarate/emtricitabine, in antiretroviral-naive HIV-1 patients: the ARTEN Trial.

  Antiviral therapy 20110101

• Added value of deep sequencing relative to population sequencing in heavily pre-treated HIV-1-infected subjects.

  PloS one 20110101

• HIV Protease Inhibitors: Effect on the Opportunistic Protozoan Parasites.

  The open medicinal chemistry journal 20110101

• Contraception in HIV-positive female adolescents.

  AIDS research and therapy 20110101

• A Multicenter, Open Labeled, Randomized, Phase III Study Comparing Lopinavir/Ritonavir Plus Atazanavir to Lopinavir/Ritonavir Plus Zidovudine and Lamivudine in Naive HIV-1-Infected Patients: 48-Week Analysis of the LORAN Trial.

  The open AIDS journal 20110101

• HIV and HAART-Associated Dyslipidemia.

  The open cardiovascular medicine journal 20110101

• Antiretroviral medications disrupt microglial phagocytosis of β-amyloid and increase its production by neurons: implications for HIV-associated neurocognitive disorders.

  Molecular brain 20110101

• Breast Cancer in the Setting of HIV.

  Pathology research international 20110101

• Clinical predictors of immune reconstitution following combination antiretroviral therapy in patients from the Australian HIV Observational Database.

  PloS one 20110101

• Treatment durability, effectiveness, and safety with atazanavir/ritonavir-based HAART regimen in treatment-naïve HIV-infected patients.

  HIV clinical trials 20110101

• Pharmacokinetics of switching unboosted atazanavir coadministered with tenofovir disoproxil fumarate from 400 mg once daily to 200 mg twice daily in HIV-positive patients.

  Antiviral therapy 20110101

• Patterns of resistance development with integrase inhibitors in HIV.

  Infection and drug resistance 20110101

• Blood Loss through AV Fistula: A Case Report and Literature Review.

  International journal of nephrology 20110101

• Improved survival of HIV-1-infected patients with progressive multifocal leukoencephalopathy receiving early 5-drug combination antiretroviral therapy.

  PloS one 20110101

• Atazanavir in children.

  Prescrire international 20110101

• Reappearance of minority K103N HIV-1 variants after interruption of ART initiated during primary HIV-1 infection.

  PloS one 20110101

• Does HAART efficacy translate to effectiveness? Evidence for a trial effect.

  PloS one 20110101

• Genital lesions: An indication for changing ART regimen.

  Indian journal of sexually transmitted diseases and AIDS 20110101

• Impact of small body weight on tenofovir-associated renal dysfunction in HIV-infected patients: a retrospective cohort study of Japanese patients.

  PloS one 20110101

• Effectiveness of protease inhibitor monotherapy versus combination antiretroviral maintenance therapy: a meta-analysis.

  PloS one 20110101

• [Evidence-based therapeutic drug monitoring of atazanavir].

  Therapie 20110101

• Treatment simplification in HIV-infected adults as a strategy to prevent toxicity, improve adherence, quality of life and decrease healthcare costs.

  Patient preference and adherence 20110101

• Nephrotoxicity of HAART.

  AIDS research and treatment 20110101

• HIV-1 protease inhibitor mutations affect the development of HIV-1 resistance to the maturation inhibitor bevirimat.

  Retrovirology 20110101

• HIV drug resistance (HIVDR) in antiretroviral therapy-naïve patients in Tanzania not eligible for WHO threshold HIVDR survey is dramatically high.

  PloS one 20110101

• Polymorphism in Gag gene cleavage sites of HIV-1 non-B subtype and virological outcome of a first-line lopinavir/ritonavir single drug regimen.

  PloS one 20110101

• HIV protease inhibitors act as competitive inhibitors of the cytoplasmic glucose binding site of GLUTs with differing affinities for GLUT1 and GLUT4.

  PloS one 20110101

• Protease inhibitors as preferred initial regimen for antiretroviral-naive HIV patients.

  AIDS reviews 20110101

• Successful tacrolimus treatment following renal transplant in a HIV-infected patient with raltegravir previously treated with a protease inhibitor based regimen.

  Drug metabolism and drug interactions 20110101

• A win-win solution?: A critical analysis of tiered pricing to improve access to medicines in developing countries.

  Globalization and health 20110101

• Prevalence and risk factors associated to chronic kidney disease in HIV-infected patients on HAART and undetectable viral load in Brazil.

  PloS one 20110101

• Saxagliptin: A dipeptidyl peptidase-4 inhibitor in the treatment of type 2 diabetes mellitus.

  Journal of pharmacology & pharmacotherapeutics 20110101

• South Asian Consensus Guidelines for the rational management of diabetes in human immunodeficiency virus/acquired immunodeficiency syndrome.

  Indian journal of endocrinology and metabolism 20110101

• Choosing a gliptin.

  Indian journal of endocrinology and metabolism 20110101

• Molecular analysis of hepatitis B virus (HBV) in an HIV co-infected patient with reactivation of occult HBV infection following discontinuation of lamivudine-including antiretroviral therapy.

  BMC infectious diseases 20110101

• Impact of comorbidities and drug therapy on development of renal impairment in a predominantly African American and Hispanic HIV clinic population.

  HIV/AIDS (Auckland, N.Z.) 20110101

• Characteristics of foot fractures in HIV-infected patients previously treated with tenofovir versus non-tenofovir-containing highly active antiretroviral therapy.

  HIV/AIDS (Auckland, N.Z.) 20110101

• Growth hormone and tesamorelin in the management of HIV-associated lipodystrophy.

  HIV/AIDS (Auckland, N.Z.) 20110101

• Role of raltegravir in the management of HIV-1 infection.

  HIV/AIDS (Auckland, N.Z.) 20110101

• AtriplaR/anti-TB combination in TB/HIV patients. Drug in focus.

  BMC research notes 20110101

• Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy.

  Retrovirology 20110101

• Effects of human immunodeficiency virus and metabolic complications on myocardial nutrient metabolism, blood flow, and oxygen consumption: a cross-sectional analysis.

  Cardiovascular diabetology 20110101

• A system out of breath: how hypoxia possibly contributes to the pathogenesis of systemic sclerosis.

  International journal of rheumatology 20110101

• Cost-effectiveness analysis of initial HIV treatment under Italian guidelines.

  ClinicoEconomics and outcomes research : CEOR 20110101

• A multifaceted analysis of HIV-1 protease multidrug resistance phenotypes.

  BMC bioinformatics 20110101

• Prevalence and impact of minority variant drug resistance mutations in primary HIV-1 infection.

  PloS one 20110101

• Critical appraisal of ticagrelor in the management of acute coronary syndrome.

  Therapeutics and clinical risk management 20110101

• Twice-daily versus once-daily antiretroviral therapy and coformulation strategies in HIV-infected adults: benefits, risks, or burden?

  Patient preference and adherence 20110101

• Comparative manufacture and cell-based delivery of antiretroviral nanoformulations.

  International journal of nanomedicine 20110101

• High FDG uptake on FDG-PET scan in HIV-1 infected patient with advanced disease.

  Acta clinica Belgica 20110101

• Clinical Use of Inhibitors of HIV-1 Integration: Problems and Prospects.

  Acta naturae 20110101

• Nanoformulated antiretroviral drug combinations extend drug release and antiretroviral responses in HIV-1-infected macrophages: implications for neuroAIDS therapeutics.

  Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20101201

• Exposure-related effects of atazanavir on the pharmacokinetics of raltegravir in HIV-1-infected patients.

  Therapeutic drug monitoring 20101201

• Analysis of mixed stones is prone to error: a study with US laboratories using micro CT for verification of sample content.

  Urological research 20101201

• Interview with Dr. Mark Cockett: current trends in screening for antiviral therapeutics. Interviewed by Nina N. Brahme and Devin J. Noblin.

  The Yale journal of biology and medicine 20101201

• Impact of atazanavir-based HAART regimen on the carotid intima-media thickness of HIV-infected persons: a comparative prospective cohort.

  AIDS (London, England) 20101127

• Pharmacokinetics, protein-binding-adjusted inhibitory quotients for atazanavir/ritonavir 300/100 mg in treatment-naïve HIV-infected patients.

  HIV medicine 20101101

• Comparison of two HIV postexposure prophylaxis regimens among men who have sex with men in Amsterdam: adverse effects do not influence compliance.

  Sexually transmitted diseases 20101101

• Outcomes of patients on dual-boosted PI regimens: experience of the Swiss HIV cohort study.

  AIDS research and human retroviruses 20101101

• Broadening the perspective when assessing evidence on boosted protease inhibitor-based regimens for initial antiretroviral therapy.

  Advances in therapy 20101101

• HIV-1 induces DCIR expression in CD4+ T cells.

  PLoS pathogens 20101101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20101101

• Role of HIV Subtype Diversity in the Development of Resistance to Antiviral Drugs.

  Viruses 20101101

• Molecular Basis for Drug Resistance in HIV-1 Protease.

  Viruses 20101101

• Effect of simplification from protease inhibitors to boosted atazanavir-based regimens in real-life conditions.

  HIV medicine 20101001

• Inaccurate reporting of mineral composition by commercial stone analysis laboratories: implications for infection and metabolic stones.

  The Journal of urology 20101001

• Efavirenz versus boosted atazanavir or zidovudine and abacavir in antiretroviral treatment-naive, HIV-infected subjects: week 48 data from the Altair study.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20101001

• Incidence of atazanavir-associated hyperbilirubinemia in Korean HIV patients: 30 months follow-up results in a population with low UDP-glucuronosyltransferase1A1*28 allele frequency.

  Journal of Korean medical science 20101001

• Recent FDA approvals and changes.

  AIDS patient care and STDs 20101001

• An efficient HPLC method for the quantitative determination of atazanavir in human plasma suitable for bioequivalence and pharmacokinetic studies in healthy human subjects.

  Journal of pharmaceutical and biomedical analysis 20100921

• Immunodeficiency and renal impairment are risk factors for HIV-associated acute renal failure.

  AIDS (London, England) 20100910

• HPLC-MS method for the quantification of nine anti-HIV drugs from dry plasma spot on glass filter and their long term stability in different conditions.

  Journal of pharmaceutical and biomedical analysis 20100905

• pH dependence of organic anion-transporting polypeptide 2B1 in Caco-2 cells: potential role in antiretroviral drug oral bioavailability and drug-drug interactions.

  The Journal of pharmacology and experimental therapeutics 20100901

• Lipid profiles in HIV-infected adults receiving atazanavir and atazanavir/ritonavir: systematic review and meta-analysis of randomized controlled trials.

  The Journal of antimicrobial chemotherapy 20100901

• KI and WU polyomaviruses and CD4+ cell counts in HIV-1-infected patients, Italy.

  Emerging infectious diseases 20100901

• Similar efficacy and tolerability of atazanavir compared with atazanavir/ritonavir, each with abacavir/lamivudine after initial suppression with abacavir/lamivudine plus ritonavir-boosted atazanavir in HIV-infected patients.

  AIDS (London, England) 20100824

• Novel protease inhibitors (PIs) containing macrocyclic components and 3(R),3a(S),6a(R)-bis-tetrahydrofuranylurethane that are potent against multi-PI-resistant HIV-1 variants in vitro.

  Antimicrobial agents and chemotherapy 20100801

• A less sensitive detector does not necessarily result in a less sensitive method: fast quantification of 13 antiretroviral analytes in plasma with liquid chromatography coupled with tandem mass spectrometry.

  Clinical chemistry and laboratory medicine 20100801

• Methadone, buprenorphine, and street drug interactions with antiretroviral medications.

  Current HIV/AIDS reports 20100801

• Protease inhibitors atazanavir, lopinavir and ritonavir are potent blockers, but poor substrates, of ABC transporters in a broad panel of ABC transporter-overexpressing cell lines.

  The Journal of antimicrobial chemotherapy 20100801

• Drug-drug interaction profiles of proton pump inhibitors.

  Clinical pharmacokinetics 20100801

• Cardiovascular risk evaluation and antiretroviral therapy effects in an HIV cohort: implications for clinical management: the CREATE 1 study.

  International journal of clinical practice 20100801

• Assessment of the role of renal organic anion transporters in drug-induced nephrotoxicity.

  Toxins 20100801

• Estimated glomerular filtration rate, chronic kidney disease and antiretroviral drug use in HIV-positive patients.

  AIDS (London, England) 20100717

• Improved HIV and substance abuse treatment outcomes for released HIV-infected prisoners: the impact of buprenorphine treatment.

  Journal of urban health : bulletin of the New York Academy of Medicine 20100701

• Simian immunodeficiency virus-infected macaques treated with highly active antiretroviral therapy have reduced central nervous system viral replication and inflammation but persistence of viral DNA.

  The Journal of infectious diseases 20100701

• Genetic factors influencing severe atazanavir-associated hyperbilirubinemia in a population with low UDP-glucuronosyltransferase 1A1*28 allele frequency.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100701

• Role of Gag in HIV Resistance to Protease Inhibitors.

  Viruses 20100701

• Resveratrol protects against protease inhibitor-induced reactive oxygen species production, reticulum stress and lipid raft perturbation.

  AIDS (London, England) 20100619

• Factors predictive of virological failure on atazanavir in 310 HIV-infected patients.

  AIDS (London, England) 20100619

• Species-specific interaction of HIV protease inhibitors with accumulation of cholyl-glycylamido-fluorescein (CGamF) in sandwich-cultured hepatocytes.

  Journal of pharmaceutical sciences 20100601

• Validation of a rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) assay for the simultaneous determination of existing and new antiretroviral compounds.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100601

• Gastrointestinal tolerability and quality of life in antiretroviral-naive HIV-1-infected patients: data from the CASTLE study.

  AIDS care 20100601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100601

• Lower atovaquone/proguanil concentrations in patients taking efavirenz, lopinavir/ritonavir or atazanavir/ritonavir.

  AIDS (London, England) 20100515

• Mass spectrometry and renal calculi.

  Journal of medicine and life 20100515

• Mid-dosing interval concentration of atazanavir and virological outcome in patients treated for HIV-1 infection.

  HIV medicine 20100501

• HIV-protease inhibitors suppress skeletal muscle fatty acid oxidation by reducing CD36 and CPT1 fatty acid transporters.

  Biochimica et biophysica acta 20100501

• Assessment of the susceptibility of mutant HIV-1 to antiviral agents.

  Journal of virological methods 20100501

• Effect of ritonavir and atazanavir on human subcutaneous preadipocyte proliferation and differentiation.

  Antiviral research 20100501

• Concentration-dependent effects and intracellular accumulation of HIV protease inhibitors in cultured CD4 T cells and primary human lymphocytes.

  The Journal of antimicrobial chemotherapy 20100501

• Evaluating the substrate-envelope hypothesis: structural analysis of novel HIV-1 protease inhibitors designed to be robust against drug resistance.

  Journal of virology 20100501

• Efficacy and safety of unboosted atazanavir in combination with lamivudine and didanosine in naive HIV type 1 patients in Senegal.

  AIDS research and human retroviruses 20100501

• Differential effects of efavirenz, lopinavir/r, and atazanavir/r on the initial viral decay rate in treatment naïve HIV-1-infected patients.

  AIDS research and human retroviruses 20100501

• Special issue: retroviral enzymes.

  Viruses 20100501

• [Protease inhibitor or non-nucleoside reverse transcriptase inhibitor. ACTG study 5202 in focus].

  MMW Fortschritte der Medizin 20100429

• The relation between treatment outcome and efavirenz, atazanavir or lopinavir exposure in the NORTHIV trial of treatment-naïve HIV-1 infected patients.

  European journal of clinical pharmacology 20100401

• Atazanavir plasma concentrations are impaired in HIV-1-infected adults simultaneously taking a methadone oral solution in a once-daily observed therapy setting.

  European journal of clinical pharmacology 20100401

• Identification of proteasome gene regulation in a rat model for HIV protease inhibitor-induced hyperlipidemia.

  Archives of toxicology 20100401

• Impact of low abundance HIV variants on response to ritonavir-boosted atazanavir or fosamprenavir given once daily with tenofovir/emtricitabine in antiretroviral-naive HIV-infected patients.

  AIDS research and human retroviruses 20100401

• Analysis of the effects of specific protease inhibitors on OPG/RANKL regulation in an osteoblast-like cell line.

  The new microbiologica 20100401

• Change to atazanavir/ritonavir treatment improves lipids but not endothelial function in patients on stable antiretroviral therapy.

  AIDS (London, England) 20100327

• Trends in uptake of recently approved antiretrovirals within a national healthcare system.

  HIV medicine 20100301

• Once-daily atazanavir/ritonavir compared with twice-daily lopinavir/ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 96-week efficacy and safety results of the CASTLE study.

  Journal of acquired immune deficiency syndromes (1999) 20100301

• Interaction of HIV protease inhibitors with OATP1B1, 1B3, and 2B1.

  Xenobiotica; the fate of foreign compounds in biological systems 20100301

• Single-tablet Quad regimen achieves high rate of virologic suppression.

  AIDS patient care and STDs 20100301

• Interaction of eight HIV protease inhibitors with the canalicular efflux transporter ABCC2 (MRP2) in sandwich-cultured rat and human hepatocytes.

  Biopharmaceutics & drug disposition 20100301

• Rapid UGT1A1 (TA)(n) genotyping by high resolution melting curve analysis for Gilbert's syndrome diagnosis.

  Clinica chimica acta; international journal of clinical chemistry 20100201

• Synthesis and biological evaluation of novel allophenylnorstatine-based HIV-1 protease inhibitors incorporating high affinity P2-ligands.

  Bioorganic & medicinal chemistry letters 20100201

• HIV protease inhibitors block oral epithelial cell DNA synthesis.

  Archives of oral biology 20100201

• Effect of nevirapine on the steady-state trough concentrations of atazanavir in HIV-infected patients receiving atazanavir/ritonavir.

  Therapeutic drug monitoring 20100201

• HIV-1 protease inhibitors with a transition-state mimic comprising a tertiary alcohol: improved antiviral activity in cells.

  Journal of medicinal chemistry 20100128

• Treatment modification in human immunodeficiency virus-infected individuals starting combination antiretroviral therapy between 2005 and 2008.

  Archives of internal medicine 20100111

• Efficacy and safety of boosted and unboosted atazanavir-containing antiretroviral regimens in real life: results from a multicentre cohort study.

  HIV medicine 20100101

• Pharmacogenetics of antiretrovirals.

  Antiviral research 20100101

• Factors influencing lopinavir and atazanavir plasma concentration.

  The Journal of antimicrobial chemotherapy 20100101

• Analysis of CYP3A4-HIV-1 protease drugs interactions by computational methods for Highly Active Antiretroviral Therapy in HIV/AIDS.

  Journal of molecular graphics & modelling 20100101

• Atazanavir-associated choledocholithiasis leading to acute hepatitis in an HIV-infected adult.

  The Annals of pharmacotherapy 20100101

• The cost and incidence of prescribing errors among privately insured HIV patients.

  PharmacoEconomics 20100101

• 96-week efficacy and safety of atazanavir, with and without ritonavir, in a HAART regimen in treatment-naive patients.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20100101

• Anticoagulant therapy for nodular regenerative hyperplasia in a HIV-infected patient.

  BMC gastroenterology 20100101

• The mitochondria-independent cytotoxic effect of nelfinavir on leukemia cells can be enhanced by sorafenib-mediated mcl-1 downregulation and mitochondrial membrane destabilization.

  Molecular cancer 20100101

• Towards a Patent Pool for HIV Medicines: The Background.

  The open AIDS journal 20100101

• Patent Pooling for Promoting Access to Antiretroviral Drugs (ARVs) - A Strategic Option for India.

  The open AIDS journal 20100101

• Berberine inhibits HIV protease inhibitor-induced inflammatory response by modulating ER stress signaling pathways in murine macrophages.

  PloS one 20100101

• Pooling ARV Drug Patents: A Pro-Access Fitting Strategy?

  The open AIDS journal 20100101

• Profile of etravirine for the treatment of HIV infection.

  Therapeutics and clinical risk management 20100101

• Extracting causal relations on HIV drug resistance from literature.

  BMC bioinformatics 20100101

• Effects of intermittent IL-2 alone or with peri-cycle antiretroviral therapy in early HIV infection: the STALWART study.

  PloS one 20100101

• Designing ARVs Patent Pool Up to Trade & Policy Evolutionary Dynamics.

  The open AIDS journal 20100101

• Impact of ritonavir, atazanavir and their combination on the CYP3A4 induction potential of efavirenz in primary human hepatocytes.

  Drug metabolism letters 20100101

• Toxicokinetic interaction between quetiapine and antiretroviral therapy following quetiapine overdose.

  Drug metabolism letters 20100101

• Decreased NK Cell FcRgamma in HIV-1 infected individuals receiving combination antiretroviral therapy: a cross sectional study.

  PloS one 20100101

• Response of a simian immunodeficiency virus (SIVmac251) to raltegravir: a basis for a new treatment for simian AIDS and an animal model for studying lentiviral persistence during antiretroviral therapy.

  Retrovirology 20100101

• Abacavir/lamivudine combination in the treatment of HIV: a review.

  Therapeutics and clinical risk management 20100101

• Raltegravir is a potent inhibitor of XMRV, a virus implicated in prostate cancer and chronic fatigue syndrome.

  PloS one 20100101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20100101

• [Adverse reactions of atazanavir, fosamprenavir and tipranavir in 'real life'].

  Therapie 20100101

• Semen may harbor HIV despite effective HAART: another piece in the puzzle.

  PloS one 20100101

• HIV protease inhibitors activate the adipocyte renin angiotensin system.

  Antiviral therapy 20100101

• Genotypic and phenotypic evolution of HIV type-1 protease during in vitro sequential or concomitant combination of atazanavir and amprenavir.

  Antiviral therapy 20100101

• Gender differences in clinical, immunological, and virological outcomes in highly active antiretroviral-treated HIV-HCV coinfected patients.

  Patient preference and adherence 20100101

• ICAAC update. Three new drugs in development, plus Isentress with Reyataz.

  Positively aware : the monthly journal of the Test Positive Aware Network 20100101

• Dynamics of lamin-A processing following precursor accumulation.

  PloS one 20100101

• An assay to monitor HIV-1 protease activity for the identification of novel inhibitors in T-cells.

  PloS one 20100101

• Prevalence and clinical significance of HIV drug resistance mutations by ultra-deep sequencing in antiretroviral-naïve subjects in the CASTLE study.

  PloS one 20100101

• Safety and efficacy of a 36-week induction regimen of abacavir/lamivudine and ritonavir-boosted atazanavir in HIV-infected patients.

  HIV clinical trials 20100101

• Transmission of human immunodeficiency virus I drug resistance - a case report. What are the clinical implications?

  European journal of medical research 20100101

• Co-lethality studied as an asset against viral drug escape: the HIV protease case.

  Biology direct 20100101

• Pulmonary Embolism Mimicking Pneumonia in a HIV Patient.

  Case reports in medicine 20100101

• Tamoxifen enhances the cytotoxic effects of nelfinavir in breast cancer cells.

  Breast cancer research : BCR 20100101

• Development of a liposomal nanodelivery system for nevirapine.

  Journal of biomedical science 20100101

• Ultra-fast analysis of plasma and intracellular levels of HIV protease inhibitors in children: a clinical application of MALDI mass spectrometry.

  PloS one 20100101

• High performance liquid chromatography using UV detection for the simultaneous quantification of the new non-nucleoside reverse transcriptase inhibitor etravirine (TMC-125), and 4 protease inhibitors in human plasma.

  Biological & pharmaceutical bulletin 20100101

• Evaluation of HIV protease and nucleoside reverse transcriptase inhibitors on proliferation, necrosis, apoptosis in intestinal epithelial cells and electrolyte and water transport and epithelial barrier function in mice.

  BMC gastroenterology 20100101

• Simplified maintenance therapy with abacavir/lamivudine and atazanavir after discontinuation of ritonavir.

  HIV clinical trials 20100101

• Susceptibility of the human retrovirus XMRV to antiretroviral inhibitors.

  Retrovirology 20100101

• Acquired Long QT Syndrome and Torsade de Pointes Associated with HIV Infection.

  Case reports in medicine 20100101

• Clinical, virological and immunological responses in Danish HIV patients receiving raltegravir as part of a salvage regimen.

  Clinical epidemiology 20100101

• Comparative biochemical analysis of recombinant reverse transcriptase enzymes of HIV-1 subtype B and subtype C.

  Retrovirology 20100101

• The bile acid sensor FXR protects against dyslipidemia and aortic plaques development induced by the HIV protease inhibitor ritonavir in mice.

  PloS one 20100101

• The global pediatric antiretroviral market: analyses of product availability and utilization reveal challenges for development of pediatric formulations and HIV/AIDS treatment in children.

  BMC pediatrics 20100101

• Safety and efficacy after switch to a saquinavir-containing antiretroviral regimen in protease inhibitor pretreated HIV-positive patients.

  European journal of medical research 20100101

• Progress in antiretroviral drug delivery using nanotechnology.

  International journal of nanomedicine 20100101

• The French national prospective cohort of patients co-infected with HIV and HCV (ANRS CO13 HEPAVIH): early findings, 2006-2010.

  BMC infectious diseases 20100101

• Unboosted atazanavir-based therapy maintains control of HIV type-1 replication as effectively as a ritonavir-boosted regimen.

  Antiviral therapy 20100101

• Raltegravir and unboosted atazanavir dual therapy in virologically suppressed antiretroviral treatment-experienced HIV patients.

  Antiviral therapy 20100101

• Saxagliptin: the evidence for its place in the treatment of type 2 diabetes mellitus.

  Core evidence 20100101

• Antiretroviral therapy optimisation without genotype resistance testing: a perspective on treatment history based models.

  PloS one 20100101

• Development, clinical utility, and place in therapy of posaconazole for prevention and treatment of invasive fungal infections.

  Drug design, development and therapy 20100101

• Pharmacokinetics and safety of twice-daily atazanavir 300 mg and raltegravir 400 mg in healthy individuals.

  Antiviral therapy 20100101

• In vitro susceptibility and virological outcome to darunavir and lopinavir are independent of HIV type-1 subtype in treatment-naive patients.

  Antiviral therapy 20100101

• Methods development for blood borne macrophage carriage of nanoformulated antiretroviral drugs.

  Journal of visualized experiments : JoVE 20100101

• Torsade de Pointes due to Methadone Use in a Patient with HIV and Hepatitis C Coinfection.

  Cardiology research and practice 20100101

• Saxagliptin for type 2 diabetes.

  Diabetes, metabolic syndrome and obesity : targets and therapy 20100101

• Lipid Metabolism and Cardiovascular Risk in HIV-1 Infection and HAART: Present and Future Problems.

  Cholesterol 20100101

• Raltegravir in combination with other antiretroviral agents for the treatment of HIV infection.

  Infection and drug resistance 20100101

• Extended use of raltegravir in the treatment of HIV-1 infection: optimizing therapy.

  Infection and drug resistance 20100101

• Novel strategies in the use of lopinavir/ritonavir for the treatment of HIV infection in children.

  HIV/AIDS (Auckland, N.Z.) 20100101

• Role of etravirine in the management of treatment-experienced patients with human immunodeficiency virus type 1.

  HIV/AIDS (Auckland, N.Z.) 20100101

• Profile of maraviroc: a CCR5 antagonist in the management of treatment-experienced HIV patients.

  HIV/AIDS (Auckland, N.Z.) 20100101

• Long-term treatment of patients with HIV-1: the role of atazanavir.

  HIV/AIDS (Auckland, N.Z.) 20100101

• New and emerging agents in the management of lipodystrophy in HIV-infected patients.

  HIV/AIDS (Auckland, N.Z.) 20100101

• Antiplatelet therapy in acute coronary syndromes: focus on ticagrelor.

  Journal of blood medicine 20100101

• Validation of an electrospray ionization LC-MS/MS method for quantitative analysis of raltegravir, etravirine, and 9 other antiretroviral agents in human plasma samples.

  Therapeutic drug monitoring 20091201

• Antiretroviral genotypic resistance mutations in HIV-1 infected Korean patients with virologic failure.

  Journal of Korean medical science 20091201

• HIV-1 Protease: Structural Perspectives on Drug Resistance.

  Viruses 20091201

• Current and Novel Inhibitors of HIV Protease.

  Viruses 20091201

• How much ritonavir is needed to boost protease inhibitors? Systematic review of 17 dose-ranging pharmacokinetic trials.

  AIDS (London, England) 20091113

• Effect of serum lipids on the pharmacokinetics of atazanavir in hyperlipidemic rats.

  Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20091101

• Atazanavir pharmacokinetics in genetically determined CYP3A5 expressors versus non-expressors.

  The Journal of antimicrobial chemotherapy 20091101

• Efavirenz: a decade of clinical experience in the treatment of HIV.

  The Journal of antimicrobial chemotherapy 20091101

• Clinically significant adverse events from a drug interaction between quetiapine and atazanavir-ritonavir in two patients.

  Pharmacotherapy 20091101

• Tenofovir coadministration is not associated with lower unboosted atazanavir plasma exposure in the clinical setting.

  Journal of acquired immune deficiency syndromes (1999) 20091101

• Clinical pharmacology, efficacy and safety of atazanavir: a review.

  Expert opinion on drug metabolism & toxicology 20091101

• Transplacental transfer of antiretroviral drugs and newborn birth weight in HIV-infected pregnant women.

  Current HIV research 20091101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20091101

• Lithiasis of semicircular canals and parotid glands: unusual stones deposition in atazanavir-treated individuals.

  AIDS (London, England) 20091023

• Atazanavir-related renal insufficiency without concurrent tenofovir.

  Enfermedades infecciosas y microbiologia clinica 20091001

• A liquid chromatography-tandem mass spectrometry assay for quantification of nevirapine, indinavir, atazanavir, amprenavir, saquinavir, ritonavir, lopinavir, efavirenz, tipranavir, darunavir and maraviroc in the plasma of patients infected with HIV.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001

• The nephrotoxic effects of HAART.

  Nature reviews. Nephrology 20091001

• Response to Crum-Cianflone et al., syphilitic hepatitis among HIV-infected patients.

  International journal of STD & AIDS 20091001

• Cost-effectiveness of preventing loss to follow-up in HIV treatment programs: a Côte d'Ivoire appraisal.

  PLoS medicine 20091001

• Report from the 5th IAS Conference on HIV Pathogenesis Treatment and Prevention. Nevirapine vs. boosted atazanavir--the ARTEN Study.

  Journal watch. AIDS clinical care 20091001

• [Iatrogenic Cushing's syndrome, diabetes mellitus and secondary adrenal failure in a human immunodeficiency virus patient treated with ritonavir boosted atazanavir and fluticasone].

  Annales d'endocrinologie 20090901

• Identification and profiling of circulating metabolites of atazanavir, a HIV protease inhibitor.

  Drug metabolism and disposition: the biological fate of chemicals 20090901

• New developments in HIV drug resistance.

  The Journal of antimicrobial chemotherapy 20090901

• The history of antiretrovirals: key discoveries over the past 25 years.

  Reviews in medical virology 20090901

• Changes in cognition during antiretroviral therapy: comparison of 2 different ranking systems to measure antiretroviral drug efficacy on HIV-associated neurocognitive disorders.

  Journal of acquired immune deficiency syndromes (1999) 20090901

• The CASTLE study: atazanavir/r versus lopinavir/r in antiretroviral-naive patients.

  Expert review of anti-infective therapy 20090901

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090901

• Human immunodeficiency virus: 25 years of diagnostic and therapeutic strategies and their impact on hepatitis B and C virus.

  Medical microbiology and immunology 20090801

• Effects of oral posaconazole on the pharmacokinetics of atazanavir alone and with ritonavir or with efavirenz in healthy adult volunteers.

  Journal of acquired immune deficiency syndromes (1999) 20090801

• Pharmacokinetics of concurrent administration of fosamprenavir and atazanavir without ritonavir in human immunodeficiency virus-negative subjects.

  Pharmacotherapy 20090801

• Effects of switching from lopinavir/ritonavir to atazanavir/ritonavir on muscle glucose uptake and visceral fat in HIV-infected patients.

  AIDS (London, England) 20090717

• A combination drug of abacavir-lamivudine-zidovudine (Trizivir) for treating HIV infection and AIDS.

  The Cochrane database of systematic reviews 20090708

• Efficacy and safety of ritonavir-boosted dual protease inhibitor therapy in antiretroviral-naive HIV-1-infected patients: the 2IP ANRS 127 study.

  The Journal of antimicrobial chemotherapy 20090701

• HIV protease inhibitors: recent clinical trials and recommendations on use.

  Expert opinion on pharmacotherapy 20090701

• Molecular dynamics and free energy studies on the wild-type and mutated HIV-1 protease complexed with four approved drugs: mechanism of binding and drug resistance.

  Journal of chemical information and modeling 20090701

• Systematic review: impaired drug absorption related to the co-administration of antisecretory therapy.

  Alimentary pharmacology & therapeutics 20090615

• Hierarchical modeling gave plausible estimates of associations between metabolic syndrome and components of antiretroviral therapy.

  Journal of clinical epidemiology 20090601

• Two different patterns of mutations are involved in the genotypic resistance score for atazanavir boosted versus unboosted by ritonavir in multiple failing patients.

  Infection 20090601

• Population pharmacokinetics of ritonavir-boosted atazanavir in HIV-infected patients and healthy volunteers.

  The Journal of antimicrobial chemotherapy 20090601

• Improvement in lipid profiles in antiretroviral-experienced HIV-positive patients with hyperlipidemia after a switch to unboosted atazanavir.

  Journal of acquired immune deficiency syndromes (1999) 20090601

• Case report: clearance of hepatitis C virus after changing the HAART regimen in a patient infected with hepatitis C virus and the human immunodeficiency virus.

  Journal of medical virology 20090601

• Neuropsychological assessment of HIV-infected populations in international settings.

  Neuropsychology review 20090601

• Efficacy and safety of atazanavir in patients with end-stage liver disease.

  Infection 20090601

• Hyperbilirubinemia during atazanavir treatment in 2,404 patients in the Italian atazanavir expanded access program and MASTER Cohorts.

  Infection 20090601

• Atazanavir: new indication. First-line treatment: fewer gastrointestinal disorders but more cases of jaundice and a risk of torsades de pointes.

  Prescrire international 20090601

• Atazanavir: a review of its use in the management of HIV-1 infection.

  Drugs 20090529

• Interactions of different inhibitors with active-site aspartyl residues of HIV-1 protease and possible relevance to pepsin.

  Proteins 20090515

• Role of cell signaling in poxvirus-mediated foreign gene expression in mammalian cells.

  Vaccine 20090514

• Effects of ritonavir-boosted darunavir vs. ritonavir-boosted atazanavir on lipid and glucose parameters in HIV-negative, healthy volunteers.

  HIV medicine 20090501

• Changes in body composition with ritonavir-boosted and unboosted atazanavir treatment in combination with Lamivudine and Stavudine: a 96-week randomized, controlled study.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090501

• Efficacy and safety of switching from boosted lopinavir to boosted atazanavir in patients with virological suppression receiving a LPV/r-containing HAART: the ATAZIP study.

  Journal of acquired immune deficiency syndromes (1999) 20090501

• Provider prescribing of 4 antiretroviral agents after implementation of drug use guidelines in the Department of Veterans Affairs.

  Journal of managed care pharmacy : JMCP 20090501

• Rhabdomyolysis in an HIV-infected patient on anti-retroviral therapy precipitated by high-dose pravastatin.

  Current drug safety 20090501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090501

• [Medication change due to side effects or possible long-term complications. Side effect management with vision].

  MMW Fortschritte der Medizin 20090430

• 2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects.

  Journal of medicinal chemistry 20090423

• Etravirine, a next-generation nonnucleoside reverse-transcriptase inhibitor.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090415

• Anti-HIV drugs: 25 compounds approved within 25 years after the discovery of HIV.

  International journal of antimicrobial agents 20090401

• A low dose of ritonavir-boosted atazanavir provides adequate pharmacokinetic parameters in HIV-1-infected Thai adults.

  Clinical pharmacology and therapeutics 20090401

• Protease inhibitors used in the treatment of HIV+ induce beta-cell apoptosis via the mitochondrial pathway and compromise insulin secretion.

  American journal of physiology. Endocrinology and metabolism 20090401

• HIV-1 protease inhibitor induced oxidative stress suppresses glucose stimulated insulin release: protection with thymoquinone.

  Experimental biology and medicine (Maywood, N.J.) 20090401

• Select updates from the 16th CROI: treatment-related cardiovascular risk, pharmacokinetic issues, and interleukin-2 use.

  The AIDS reader 20090401

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20090401

• Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy: final 48-week clinical and virologic outcomes.

  The Journal of infectious diseases 20090315

• Effect of atazanavir versus other protease inhibitor-containing antiretroviral therapy on endothelial function in HIV-infected persons: randomised controlled trial.

  Heart (British Cardiac Society) 20090301

• Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line.

  Journal of neuroscience research 20090301

• GRL-02031, a novel nonpeptidic protease inhibitor (PI) containing a stereochemically defined fused cyclopentanyltetrahydrofuran potent against multi-PI-resistant human immunodeficiency virus type 1 in vitro.

  Antimicrobial agents and chemotherapy 20090301

• Maintaining reduced viral fitness and CD4 response in HIV-infected patients with viremia receiving a boosted protease inhibitor.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20090301

• Hepatotoxicity and gastrointestinal intolerance when healthy volunteers taking rifampin add twice-daily atazanavir and ritonavir.

  Journal of acquired immune deficiency syndromes (1999) 20090301

• Gag mutations strongly contribute to HIV-1 resistance to protease inhibitors in highly drug-experienced patients besides compensating for fitness loss.

  PLoS pathogens 20090301

• Protease inhibitor levels in hair strongly predict virologic response to treatment.

  AIDS (London, England) 20090220

• Quantification of HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors in peripheral blood mononuclear cell lysate using liquid chromatography coupled with tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090215

• Warfarin-antiretroviral interactions.

  The Annals of pharmacotherapy 20090201

• Cost-effectiveness analysis of lopinavir/ritonavir and atazanavir+ritonavir regimens in the CASTLE study.

  Advances in therapy 20090201

• [Atazanavir-induced nephrolithiasis].

  Enfermedades infecciosas y microbiologia clinica 20090201

• HIV monotherapy with ritonavir-boosted protease inhibitors: a systematic review.

  AIDS (London, England) 20090128

• Low atazanavir concentrations in cerebrospinal fluid.

  AIDS (London, England) 20090102

• Extension of the SAEM algorithm for nonlinear mixed models with 2 levels of random effects.

  Biostatistics (Oxford, England) 20090101

• Quantification of 8 HIV-protease inhibitors and 2 nonnucleoside reverse transcriptase inhibitors by ultra-performance liquid chromatography with diode array detection.

  Clinical chemistry 20090101

• Antiretroviral-related adipocyte dysfunction and lipodystrophy in HIV-infected patients: Alteration of the PPARγ-dependent pathways.

  PPAR research 20090101

• Survey of physician knowledge regarding antiretroviral medications in hospitalized HIV-infected patients.

  Journal of the International AIDS Society 20090101

• Top stories of 2008. Beyond abacavir/3TC: good news on first-line regimens.

  AIDS clinical care 20090101

• Comparison of Markov model and discrete-event simulation techniques for HIV.

  PharmacoEconomics 20090101

• Raltegravir with unboosted atazanavir 300 mg twice daily in antiretroviral treatment-experienced participants.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101

• A randomized, controlled trial of initial anti-retroviral therapy with abacavir/lamivudine/zidovudine twice-daily compared to atazanavir once-daily with lamivudine/zidovudine twice-daily in HIV-infected patients over 48 weeks (ESS100327, the ACTION Study).

  AIDS research and therapy 20090101

• Role of atazanavir in the treatment of HIV infection.

  Therapeutics and clinical risk management 20090101

• Emtricitabine/tenofovir disoproxil fumarate: in combination with a protease inhibitor in HIV-1 infection.

  Drugs 20090101

• Adrenal suppression due to an interaction between ritonavir and injected triamcinolone: a case report.

  AIDS research and therapy 20090101

• Emerging role of integrase inhibitors in the management of treatment-experienced patients with HIV infection.

  Therapeutics and clinical risk management 20090101

• Serum lipid profiles among patients initiating ritonavir-boosted atazanavir versus efavirenz-based regimens.

  AIDS research and therapy 20090101

• Low-abundance HIV drug-resistant viral variants in treatment-experienced persons correlate with historical antiretroviral use.

  PloS one 20090101

• Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection.

  PloS one 20090101

• Differences in resistance mutations among HIV-1 non-subtype B infections: a systematic review of evidence (1996-2008).

  Journal of the International AIDS Society 20090101

• Anti-HIV agents. Atazanavir and raltegravir--an interesting combination.

  TreatmentUpdate 20090101

• Host sequence motifs shared by HIV predict response to antiretroviral therapy.

  BMC medical genomics 20090101

• Unboosted atazanavir plus co-formulated lamivudine/abacavir as a ritonavir-sparing simplification strategy in routine clinical practice.

  HIV clinical trials 20090101

• Occurrence of selective ritonavir nonadherence and dose-staggering in recipients of boosted HIV-1 protease inhibitor therapy.

  HIV clinical trials 20090101

• Baseline lipid levels rather than the presence of reported body shape changes determine the degree of improvement in lipid levels after switching to atazanavir.

  HIV clinical trials 20090101

• Novel methodology for antiretroviral quantitation in the female genital tract.

  HIV clinical trials 20090101

• The Impact of HIV and Malaria Coinfection: What Is Known and Suggested Venues for Further Study.

  Interdisciplinary perspectives on infectious diseases 20090101

• Pharmacotherapy of pediatric and adolescent HIV infection.

  Therapeutics and clinical risk management 20090101

• Managing treatment-experienced pediatric and adolescent HIV patients: role of darunavir.

  Therapeutics and clinical risk management 20090101

• HIV-associated bladder cancer: a case series evaluating difficulties in diagnosis and management.

  BMC urology 20090101

• Short-term effect of ritonavir-boosted atazanavir in hepatitis B and/or C co-infected, treatment-experienced HIV patients.

  HIV clinical trials 20090101

• Impact of first-line protease inhibitors on predicted resistance to tipranavir in HIV-1-infected patients with virological failure.

  BMC infectious diseases 20090101

• Pairwise and higher-order correlations among drug-resistance mutations in HIV-1 subtype B protease.

  BMC bioinformatics 20090101

• Comparison of 3-drug versus 4-drug and PI versus non-PI combinations as initial HAART: experience from 1998 to 2007.

  Journal of the International Association of Physicians in AIDS Care (Chicago, Ill. : 2002) 20090101

• Drugs associated with more suicidal ideations are also associated with more suicide attempts.

  PloS one 20090101

• XVII International AIDS Conference: From Evidence to Action - Clinical and biomedical prevention science.

  Journal of the International AIDS Society 20090101

• High molecular weight form of adiponectin in antiretroviral drug-induced dyslipidemia in HIV-infected Japanese individuals based on in vivo and in vitro analyses.

  Internal medicine (Tokyo, Japan) 20090101

• Oxidative imbalance in HIV-1 infected patients treated with antiretroviral therapy.

  Journal of biomedicine & biotechnology 20090101

• Electrocardiogram abnormalities with atazanavir and lopinavir/ritonavir.

  HIV clinical trials 20090101

• P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir.

  Antiviral therapy 20090101

• Nilotinib: optimal therapy for patients with chronic myeloid leukemia and resistance or intolerance to imatinib.

  Drug design, development and therapy 20090101

• Algorithms for the assessment and management of insomnia in primary care.

  Patient preference and adherence 20090101

• First-line boosted protease inhibitor-based regimens in treatment-naive HIV-1-infected patients--making a good thing better.

  AIDS reviews 20090101

• The association between alcohol use, alcohol use disorders and tuberculosis (TB). A systematic review.

  BMC public health 20090101

• Correlations between atazanavir C(trough )and hyperbilirubinemia: a case report.

  Journal of medical case reports 20090101

• Severe skin rash associated with atazanavir.

  The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale 20090101

• Raltegravir: The evidence of its therapeutic value in HIV-1 infection.

  Core evidence 20090101

• Etravirine (TMC-125): The evidence for its place in the treatment of HIV-1 infection.

  Core evidence 20090101

• Rapid and persistent selection of the K103N mutation as a majority quasispecies in a HIV1-patient exposed to efavirenz for three weeks: a case report and review of the literature.

  Journal of medical case reports 20090101

• New approaches in the management of chronic hepatitis B: role of tenofovir.

  Infection and drug resistance 20090101

• Role of darunavir in the management of HIV infection.

  HIV/AIDS (Auckland, N.Z.) 20090101

• The effect of atazanavir and atazanavir/ritonavir on UDP-glucuronosyltransferase using lamotrigine as a phenotypic probe.

  Clinical pharmacology and therapeutics 20081201

• Interaction between cat's claw and protease inhibitors atazanavir, ritonavir and saquinavir.

  European journal of clinical pharmacology 20081201

• A pilot study on the efficacy, pharmacokinetics and safety of atazanavir in patients with end-stage liver disease.

  The Journal of antimicrobial chemotherapy 20081201

• Population pharmacokinetics of atazanavir in human immunodeficiency virus-infected patients.

  Therapeutic drug monitoring 20081201

• An HPLC-PDA method for the simultaneous quantification of the HIV integrase inhibitor raltegravir, the new nonnucleoside reverse transcriptase inhibitor etravirine, and 11 other antiretroviral agents in the plasma of HIV-infected patients.

  Therapeutic drug monitoring 20081201

• Atazanavir: its role in HIV treatment.

  Expert review of anti-infective therapy 20081201

• CASTLE analysis finds no benefit for once daily dosing.

  Project Inform perspective 20081201

• 96-week data from CASTLE study presented.

  Project Inform perspective 20081201

• Report from the 2008 joint ICAAC/IDSA meeting. Darunavir and atazanavir: 96-week data from ARTEMIS and CASTLE.

  AIDS clinical care 20081201

• Once-daily fosamprenavir with ritonavir in the treatment of HIV infection in therapy-naïve patients.

  Therapeutics and clinical risk management 20081201

• [Introduction. Usefulness of atazanavir in the treatment of patients infected by human immunodeficiency virus].

  Enfermedades infecciosas y microbiologia clinica 20081201

• [Pharmacology, pharmacokinetic features and interactions of atazanavir].

  Enfermedades infecciosas y microbiologia clinica 20081201

• [Efficacy of atazanavir in treatment-naive patients].

  Enfermedades infecciosas y microbiologia clinica 20081201

• [Efficacy of atazanavir in simplification regimens].

  Enfermedades infecciosas y microbiologia clinica 20081201

• [Efficacy of atazanavir in rescue therapy].

  Enfermedades infecciosas y microbiologia clinica 20081201

• [Viral resistance and genetic barrier of atazanavir].

  Enfermedades infecciosas y microbiologia clinica 20081201

• [Lipid profile of atazanavir].

  Enfermedades infecciosas y microbiologia clinica 20081201

• [Adverse effects of atazanavir].

  Enfermedades infecciosas y microbiologia clinica 20081201

• [Safety of atazanavir in patients with HIV and hepatitis B and/or C virus coinfection].

  Enfermedades infecciosas y microbiologia clinica 20081201

• [Utility of atazanavir in special populations].

  Enfermedades infecciosas y microbiologia clinica 20081201

• [Clinical utility of atazanavir].

  Enfermedades infecciosas y microbiologia clinica 20081201

• Increase in serum bilirubin in HIV/hepatitis-C virus-coinfected patients on atazanavir therapy following initiation of pegylated-interferon and ribavirin.

  AIDS (London, England) 20081130

• Emtricitabine: Inhibitor and substrate of multidrug resistance associated protein.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20081115

• Elevated alkaline phosphatase with raltegravir in a treatment experienced HIV patient.

  AIDS (London, England) 20081112

• Platelet-leucocyte adhesion markers before and after the initiation of antiretroviral therapy with HIV protease inhibitors.

  The Journal of antimicrobial chemotherapy 20081101

• Association of a single-nucleotide polymorphism in the pregnane X receptor (PXR 63396C-->T) with reduced concentrations of unboosted atazanavir.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081101

• Rapid allelic discrimination by TaqMan PCR for the detection of the Gilbert's syndrome marker UGT1A1*28.

  The Journal of molecular diagnostics : JMD 20081101

• Nucleoside-free boosted double PI regimen: significant CD4+ T-cell recovery in patients with poor immunologic response despite virologic suppression.

  Current HIV research 20081101

• 96-week CASTLE data show similar efficacy results.

  AIDS patient care and STDs 20081101

• FDA notifications. Alternative dosing regimen for atazanavir is approved.

  AIDS alert 20081101

• Clinical pharmacology of HIV protease inhibitors in pregnancy.

  Current opinion in HIV and AIDS 20081101

• [Pharmacokinetics and interactions of raltegravir].

  Enfermedades infecciosas y microbiologia clinica 20081101

• Solid lipid nanoparticles enhance the delivery of the HIV protease inhibitor, atazanavir, by a human brain endothelial cell line.

  Pharmaceutical research 20081001

• Trends in the prescription of antiretroviral drugs and impact on plasma HIV-RNA measurements.

  The Journal of antimicrobial chemotherapy 20081001

• Acute renal failure due to bilateral ureteral stone impaction in an HIV-positive patient.

  Urological research 20081001

• Maraviroc: in vitro assessment of drug-drug interaction potential.

  British journal of clinical pharmacology 20081001

• Low-dose, once-daily atazanavir/ritonavir (200/100): an effective treatment for HIV-infected patients in Thailand.

  Journal of acquired immune deficiency syndromes (1999) 20081001

• FDA notifications. Updates made to Reyataz package insert.

  AIDS alert 20081001

• Pharmacokinetic properties and tolerability of bevirimat and atazanavir in healthy volunteers: an open-label, parallel-group study.

  Clinical therapeutics 20081001

• Lopinavir/ritonavir in the treatment of HIV-1 infection: a review.

  Therapeutics and clinical risk management 20081001

• Suboptimal inhibition of protease activity in human immunodeficiency virus type 1: effects on virion morphogenesis and RNA maturation.

  Virology 20080915

• The steady-state pharmacokinetics of atazanavir/ritonavir in HIV-1-infected adult outpatients is not affected by gender-related co-factors.

  The Journal of antimicrobial chemotherapy 20080901

• A survey of the syntheses of active pharmaceutical ingredients for antiretroviral drug combinations critical to access in emerging nations.

  Antiviral research 20080901

• Comparison of ABC transporter modulation by atazanavir in lymphocytes and human brain endothelial cells: ABC transporters are involved in the atazanavir-limited passage across an in vitro human model of the blood-brain barrier.

  AIDS research and human retroviruses 20080901

• Labeling changes for Reyataz.

  AIDS patient care and STDs 20080901

• CASTLE data show no gender differences.

  AIDS patient care and STDs 20080901

• Correlation between HIV-1 RNA load in blood and seminal plasma depending on antiretroviral treatment status, regimen and penetration of semen by antiretroviral drugs.

  Current HIV research 20080901

• HIV infection in the elderly.

  Clinical interventions in aging 20080901

• A king in the CASTLE? Optimum initial HIV protease inhibitor.

  Lancet (London, England) 20080823

• Once-daily atazanavir/ritonavir versus twice-daily lopinavir/ritonavir, each in combination with tenofovir and emtricitabine, for management of antiretroviral-naive HIV-1-infected patients: 48 week efficacy and safety results of the CASTLE study.

  Lancet (London, England) 20080823

• Electrocardiographic changes in HIV-infected, drug experienced patients treated with atazanavir.

  AIDS (London, England) 20080820

• A study of the analytical behaviour of selected new molecular entities using electrospray ionisation ion trap mass spectrometry, liquid chromatography, gas chromatography and polarography and their determination in serum at therapeutic concentrations.

  Analytica chimica acta 20080815

• No impairment of endothelial function or insulin sensitivity with 4 weeks of the HIV protease inhibitors atazanavir or lopinavir-ritonavir in healthy subjects without HIV infection: a placebo-controlled trial.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080815

• Inorganic polyhedral metallacarborane inhibitors of HIV protease: a new approach to overcoming antiviral resistance.

  Journal of medicinal chemistry 20080814

• CYP3A induction and inhibition by different antiretroviral regimens reflected by changes in plasma 4beta-hydroxycholesterol levels.

  European journal of clinical pharmacology 20080801

• The HIV-1 protease resistance mutation I50L is associated with resistance to atazanavir and susceptibility to other protease inhibitors in multiple mutational contexts.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20080801

• A case of HIV co-infected with hepatitis B virus precore/core deletion mutant treated by entecavir.

  Hepatology research : the official journal of the Japan Society of Hepatology 20080801

• Neutralizing antibody and anti-retroviral drug sensitivities of HIV-1 isolates resistant to small molecule CCR5 inhibitors.

  Virology 20080801

• Ritonavir-boosted atazanavir, methadone, and ventricular tachycardia: 2 case reports.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080801

• Determination of unbound antiretroviral drug concentrations by a modified ultrafiltration method reveals high variability in the free fraction.

  Therapeutic drug monitoring 20080801

• Time to virological failure with atazanavir/ritonavir and lopinavir/ritonavir, with or without an H2-receptor blocker, not significantly different in HIV observational database study.

  International journal of STD & AIDS 20080801

• Two cases of multidrug-resistant human immunodeficiency virus infection treated with atazanavir and lopinavir/ritonavir combination therapy.

  Journal of Korean medical science 20080801

• Combating HIV resistance - focus on darunavir.

  Therapeutics and clinical risk management 20080801

• The Relationship Between HIV Infection and Cardiovascular Disease.

  Current cardiology reviews 20080801

• Effect of atazanavir and ritonavir on the differentiation and adipokine secretion of human subcutaneous and omental preadipocytes.

  AIDS (London, England) 20080711

• HIV protease inhibitors that block GLUT4 precipitate acute, decompensated heart failure in a mouse model of dilated cardiomyopathy.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080701

• Cellular accumulation of cholyl-glycylamido-fluorescein in sandwich-cultured rat hepatocytes: kinetic characterization, transport mechanisms, and effect of human immunodeficiency virus protease inhibitors.

  Drug metabolism and disposition: the biological fate of chemicals 20080701

• Family 1 uridine-5'-diphosphate glucuronosyltransferases (UGT1A): from Gilbert's syndrome to genetic organization and variability.

  Archives of toxicology 20080701

• Atazanavir modestly increases plasma levels of raltegravir in healthy subjects.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080701

• Determination of atazanavir in human plasma by high-performance liquid chromatography with UV detection.

  Journal of chromatographic science 20080701

• Differential effects of ketoconazole on exposure to temsirolimus following intravenous infusion of temsirolimus.

  British journal of cancer 20080603

• Quality control of protease inhibitors.

  Journal of pharmaceutical sciences 20080601

• The genotypic inhibitory quotient: a predictive factor of atazanavir response in HIV-1-infected treatment-experienced patients.

  Journal of acquired immune deficiency syndromes (1999) 20080601

• Effects of HIV antiretrovirals on the pharmacokinetics of hormonal contraceptives.

  The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20080601

• Switch from ritonavir-boosted to unboosted atazanavir guided by therapeutic drug monitoring.

  AIDS research and human retroviruses 20080601

• Pharmacogenetics of Gilbert's syndrome.

  Pharmacogenomics 20080601

• Long-term pharmacokinetic efficacy and safety of low-dose ritonavir as a booster and atazanavir pharmaceutical formulation based on solid dispersion system in rats.

  Biological & pharmaceutical bulletin 20080601

• Effects of atazanavir/ritonavir or fosamprenavir/ritonavir on the pharmacokinetics of rosuvastatin.

  Journal of cardiovascular pharmacology 20080601

• Screening and Management of HIV-2-Infected Individuals in Northern Italy.

  AIDS patient care and STDs 20080601

• Pharmacogenomics of antiretrovirals.

  Recent patents on anti-infective drug discovery 20080601

• Response of feline immunodeficiency virus (FIV) to tipranavir may provide new clues for development of broad-based inhibitors of retroviral proteases acting on drug-resistant HIV-1.

  Current HIV research 20080601

• Atriplatrade mark - HIV therapy in one pill.

  Therapeutics and clinical risk management 20080601

• Stability of antiretroviral regimens in patients with viral suppression.

  AIDS (London, England) 20080531

• Quantification of protease inhibitors and non-nucleoside reverse transcriptase inhibitors in dried blood spots by liquid chromatography-triple quadrupole mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080515

• Effects of acid-reducing agents on the pharmacokinetics of lopinavir/ritonavir and ritonavir-boosted atazanavir.

  Journal of clinical pharmacology 20080501

• The compound 6-chloro-1,4-dihydro-4-oxo-1-(beta-D-ribofuranosyl) quinoline-3-carboxylic acid inhibits HIV-1 replication by targeting the enzyme reverse transcriptase.

  Current HIV research 20080501

• [Acute renal failure associated with the use of tenofovir combined with atazanavir in patients with HIV infection].

  Enfermedades infecciosas y microbiologia clinica 20080501

• FDA notifications. Atazanavir capsule label is updated for pediatric patients.

  AIDS alert 20080501

• [Toxicogenetics of antiretroviral treatment (II): neurotoxicity, hepatotoxicity, lactic acidosis, kidney damage, and other adverse effects of antiretroviral drugs].

  Enfermedades infecciosas y microbiologia clinica 20080501

• [Applicability of pharmacogenetic studies in daily clinical practice].

  Enfermedades infecciosas y microbiologia clinica 20080501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20080501

• Inhibitory quotient in HIV pharmacology.

  Current opinion in HIV and AIDS 20080501

• Differences in the pharmacokinetics of protease inhibitors between healthy volunteers and HIV-infected persons.

  Current opinion in HIV and AIDS 20080501

• [Metabolic changes in PI-based HAART. Change to atazanavir: continued effectiveness with improved lipid profile].

  MMW Fortschritte der Medizin 20080428

• Diagnosis and management of HIV drug hypersensitivity.

  The Journal of allergy and clinical immunology 20080401

• Characterization of a novel human immunodeficiency virus type 1 protease inhibitor, A-790742.

  Antimicrobial agents and chemotherapy 20080401

• Liver toxicity of antiretroviral combinations including atazanavir/ritonavir in patients co-infected with HIV and hepatitis viruses: impact of pre-existing liver fibrosis.

  The Journal of antimicrobial chemotherapy 20080401

• Inhibition of HIV-2 protease by HIV-1 protease inhibitors in clinical use.

  Chemical biology & drug design 20080401

• Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers.

  British journal of clinical pharmacology 20080401

• Atazanavir and lopinavir with ritonavir alone or in combination: analysis of pharmacokinetic interaction and predictors of drug exposure.

  HIV medicine 20080401

• New pediatric dosing recommendations for atazanavir.

  AIDS patient care and STDs 20080401

• Risk of early virological failure of once-daily tenofovir-emtricitabine plus twice-daily nevirapine in antiretroviral therapy-naive HIV-infected patients.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080401

• Raltegravir: first in class HIV integrase inhibitor.

  Therapeutics and clinical risk management 20080401

• Cardiovascular risk score change in HIV-1-infected patients switched to an atazanavir-based combination antiretroviral regimen.

  HIV medicine 20080301

• Lipodystrophy and weight changes: data from the Swiss HIV Cohort Study, 2000-2006.

  HIV medicine 20080301

• Lipid-lowering efficacy and safety after switching to atazanavir-ritonavir-based highly active antiretroviral therapy in patients with human immunodeficiency virus.

  Pharmacotherapy 20080301

• CASTLE study showed similar efficacy.

  AIDS patient care and STDs 20080301

• Revised package insert for atazanavir.

  AIDS clinical care 20080301

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20080301

• FDA notifications. FDA tentatively approves generic atazanavir.

  AIDS alert 20080301

• FDA notifications. Revised atazanavir package insert.

  AIDS alert 20080301

• Anti-HIV agents. The Castle study: lopinavir vs. atazanavir.

  TreatmentUpdate 20080301

• Two-carbon-elongated HIV-1 protease inhibitors with a tertiary-alcohol-containing transition-state mimic.

  Journal of medicinal chemistry 20080227

• Efficacy and safety of atazanavir, with or without ritonavir, as part of once-daily highly active antiretroviral therapy regimens in antiretroviral-naive patients.

  Journal of acquired immune deficiency syndromes (1999) 20080201

• Structure-activity relationships of novel HIV-1 protease inhibitors containing the 3-amino-2-chlorobenzoyl-allophenylnorstatine structure.

  Bioorganic & medicinal chemistry 20080201

• Evolution of the HIV-1 protease region in heavily pretreated HIV-1 infected patients receiving Atazanavir.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20080201

• Pharmacokinetics of antiretroviral regimens containing tenofovir disoproxil fumarate and atazanavir-ritonavir in adolescents and young adults with human immunodeficiency virus infection.

  Antimicrobial agents and chemotherapy 20080201

• A ten-year analysis of the incidence and risk factors for acute pancreatitis requiring hospitalization in an urban HIV clinical cohort.

  AIDS patient care and STDs 20080201

• Improvement in insulin sensitivity and dyslipidemia in protease inhibitor-treated adult male patients after switch to atazanavir/ritonavir.

  Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20080201

• Progression of Kaposi sarcoma associated with iatrogenic Cushing syndrome in a person with HIV/AIDS.

  The AIDS reader 20080201

• Urolithiasis under atazanavir boosted and tenofovir therapy: a case report.

  Journal of chemotherapy (Florence, Italy) 20080201

• Atazanavir/ritonavir: a review of its use in HIV therapy.

  Drugs of today (Barcelona, Spain : 1998) 20080201

• Long-distance interactive expert advice in highly treatment-experienced HIV-infected patients.

  The Journal of antimicrobial chemotherapy 20080101

• Efficacy and safety of replacing lopinavir with atazanavir in HIV-infected patients with undetectable plasma viraemia: final results of the SLOAT trial.

  The Journal of antimicrobial chemotherapy 20080101

• HIV-1 protease inhibitors: effects on HIV-2 replication and resistance.

  Trends in pharmacological sciences 20080101

• Viro-immunologic response to ritonavir-boosted or unboosted atazanavir in a large cohort of multiply treated patients: the CARe Study.

  AIDS patient care and STDs 20080101

• Plasma levels, safety, and 60-week efficacy of a once-daily double-boosted protease inhibitor regimen of atazanavir, saquinavir, and ritonavir.

  Journal of acquired immune deficiency syndromes (1999) 20080101

• Drug interactions between HIV protease inhibitors and acid-reducing agents.

  Clinical pharmacokinetics 20080101

• Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT mice.

  PLoS medicine 20080101

• The incidence of multidrug and full class resistance in HIV-1 infected patients is decreasing over time (2001-2006) in Portugal.

  Retrovirology 20080101

• Implementation and effectiveness of antiretroviral therapy in Greenland.

  Emerging infectious diseases 20080101

• Adaptation of antiretroviral therapy in human immunodeficiency virus infection with central nervous system involvement.

  Journal of neurovirology 20080101

• Transmitted drug resistance, selection of resistance mutations and moderate antiretroviral efficacy in HIV-2: analysis of the HIV-2 Belgium and Luxembourg database.

  BMC infectious diseases 20080101

• Efficacy and safety of once-daily regimens in the treatment of HIV infection.

  Drugs 20080101

• Fosamprenavir or atazanavir once daily boosted with ritonavir 100 mg, plus tenofovir/emtricitabine, for the initial treatment of HIV infection: 48-week results of ALERT.

  AIDS research and therapy 20080101

• Acute renal failure in an AIDS patient on tenofovir: a case report.

  Journal of medical case reports 20080101

• Proteochemometric modeling of HIV protease susceptibility.

  BMC bioinformatics 20080101

• Case presentation: nephrolithiasis in a patient treated with atazanavir.

  The Journal of the Association of Nurses in AIDS Care : JANAC 20080101

• Atazanavir in patients with persistent viral replication despite HAART: results from the French prospective NADIS cohort.

  HIV clinical trials 20080101

• Once-daily abacavir/lamivudine and ritonavir-boosted atazanavir for the treatment of HIV-1 infection in antiretroviral-naïve patients: a 48-week pilot study.

  HIV clinical trials 20080101

• An accurate definition of the status of inactive hepatitis B virus carrier by a combination of biomarkers (FibroTest-ActiTest) and viral load.

  PloS one 20080101

• The inverse starving test is not a suitable provocation test for Gilbert's syndrome.

  BMC research notes 20080101

• Evaluation of efficacy, safety, pharmacokinetics, and adherence in HIV-1-infected, antiretroviral-naïve patients treated with ritonavir-boosted atazanavir plus fixed-dose tenofovir DF/emtricitabine given once daily.

  HIV clinical trials 20080101

• Significant improvements in self-reported gastrointestinal tolerability, quality of life, patient satisfaction, and adherence with lopinavir/ritonavir tablet formulation compared with soft gel capsules.

  AIDS research and therapy 20080101

• Resting regulatory CD4 T cells: a site of HIV persistence in patients on long-term effective antiretroviral therapy.

  PloS one 20080101

• Gateways to clinical trials. July-August 2008.

  Methods and findings in experimental and clinical pharmacology 20080101

• Dyslipidemia and cardiovascular disease risk factor management in HIV-1-infected subjects treated with HAART in the Spanish VACH cohort.

  The open AIDS journal 20080101

• Double-boosted protease inhibitor antiretroviral regimens: what role?

  Drugs 20080101

• Magnitude and complexity of rectal mucosa HIV-1-specific CD8+ T-cell responses during chronic infection reflect clinical status.

  PloS one 20080101

• Prevention of the sexual transmission of HIV-1: preparing for success.

  Journal of the International AIDS Society 20080101

• Pharmacokinetics of atazanavir/ritonavir once daily and lopinavir/ritonavir twice and once daily over 72 h following drug cessation.

  Antiviral therapy 20080101

• XVII International AIDS Conference--Mexico City, August 3-8, 2008. Metabolic complications and hepatitis co-infection. News from the International AIDS Conference.

  Positively aware : the monthly journal of the Test Positive Aware Network 20080101

• Role of genetic diversity amongst HIV-1 non-B subtypes in drug resistance: a systematic review of virologic and biochemical evidence.

  AIDS reviews 20080101

• [Simplification of HAART scheme--treatment optimization].

  Terapevticheskii arkhiv 20080101

• Efficacy and safety of ritonavir-boosted and unboosted atazanavir among antiretroviral-naïve patients.

  HIV clinical trials 20080101

• Determinants of Treatment Access in a Population-based Cohort of HIV-positive Men and Women Living in Argentina.

  Journal of the International AIDS Society 20080101

• Raltegravir in the management of HIV-infected patients.

  Drug design, development and therapy 20080101

• Interaction between buprenorphine and atazanavir or atazanavir/ritonavir.

  Drug and alcohol dependence 20071201

• Overview of boosted protease inhibitors in treatment-experienced HIV-infected patients.

  The Journal of antimicrobial chemotherapy 20071201

• Initiating highly active antiretroviral therapy with newer protease inhibitors is associated with better survival compared to first-generation protease inhibitors or nevirapine.

  AIDS patient care and STDs 20071201

• Characterization of HIV-1 subtypes and viral antiretroviral drug resistance in men who have sex with men in Beijing, China.

  AIDS (London, England) 20071201

• Review of tenofovir-emtricitabine.

  Therapeutics and clinical risk management 20071201

• Atazanavir plus low-dose ritonavir in pregnancy: pharmacokinetics and placental transfer.

  AIDS (London, England) 20071130

• HPLC-MS method for the simultaneous quantification of the new HIV protease inhibitor darunavir, and 11 other antiretroviral agents in plasma of HIV-infected patients.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071115

• HIV-1 protease inhibitors nelfinavir and atazanavir induce malignant glioma death by triggering endoplasmic reticulum stress.

  Cancer research 20071115

• Atazanavir crystal nephropathy.

  AIDS (London, England) 20071112

• Effects of atazanavir/ritonavir and lopinavir/ritonavir on glucose uptake and insulin sensitivity.

  AIDS (London, England) 20071112

• HIV protease inhibitors increase TNF-alpha and IL-6 expression in macrophages: involvement of the RNA-binding protein HuR.

  Atherosclerosis 20071101

• Inhibition of P-glycoprotein and multidrug resistance-associated proteins modulates the intracellular concentration of lopinavir in cultured CD4 T cells and primary human lymphocytes.

  The Journal of antimicrobial chemotherapy 20071101

• Evolution of antiretroviral drug costs in Brazil in the context of free and universal access to AIDS treatment.

  PLoS medicine 20071101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20071101

• Urolithiasis in HIV-positive patients treated with atazanavir.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20071015

• Prevalence of darunavir resistance mutations in HIV-1-infected patients failing other protease inhibitors.

  The Journal of antimicrobial chemotherapy 20071001

• Tenofovir comedication does not impair the steady-state pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected adults.

  European journal of clinical pharmacology 20071001

• Therapeutic drug monitoring of the HIV protease inhibitor atazanavir in clinical practice.

  The Journal of antimicrobial chemotherapy 20071001

• Gene expression profiling of rat liver reveals a mechanistic basis for ritonavir-induced hyperlipidemia.

  Genomics 20071001

• Steady-state pharmacokinetics of once-daily fosamprenavir/ritonavir and atazanavir/ritonavir alone and in combination with 20 mg omeprazole in healthy volunteers.

  HIV medicine 20071001

• Treatment of an atazanivir associated grade 4 hyperbilirubinaemia with efavirenz.

  Gut 20071001

• Assessing the impact of substance use and hepatitis coinfection on atazanavir and lopinavir trough concentrations in HIV-infected patients during therapeutic drug monitoring.

  Therapeutic drug monitoring 20071001

• Monitoring atazanavir concentrations with boosted or unboosted regimens in HIV-infected patients in routine clinical practice.

  Therapeutic drug monitoring 20071001

• Reyataz monotherapy study stopped.

  Project Inform perspective 20071001

• Potent inhibition of HIV-1 replication by novel non-peptidyl small molecule inhibitors of protease dimerization.

  The Journal of biological chemistry 20070928

• Antiretroviral drug exposure in the female genital tract: implications for oral pre- and post-exposure prophylaxis.

  AIDS (London, England) 20070912

• Efavirenz urolithiasis.

  AIDS (London, England) 20070912

• Design and synthesis of HIV-1 protease inhibitors incorporating oxazolidinones as P2/P2' ligands in pseudosymmetric dipeptide isosteres.

  Journal of medicinal chemistry 20070906

• Effect of concomitantly administered rifampin on the pharmacokinetics and safety of atazanavir administered twice daily.

  Antimicrobial agents and chemotherapy 20070901

• In vitro antiviral activity of the novel, tyrosyl-based human immunodeficiency virus (HIV) type 1 protease inhibitor brecanavir (GW640385) in combination with other antiretrovirals and against a panel of protease inhibitor-resistant HIV.

  Antimicrobial agents and chemotherapy 20070901

• Interactions between protease inhibitors and acid-reducing agents: a systematic review.

  HIV medicine 20070901

• Modulation of heme and myristate binding to human serum albumin by anti-HIV drugs. An optical and NMR spectroscopic study.

  The FEBS journal 20070901

• Atazanavir-associated menorrhagia.

  International journal of STD & AIDS 20070901

• Patient preferences among third agent HIV medications: a US and German perspective.

  AIDS care 20070901

• Early virologic rebound in a pilot trial of ritonavir-boosted atanazavir as maintenance monotherapy.

  Journal of acquired immune deficiency syndromes (1999) 20070901

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20070901

• Virological failure and subsequent resistance profiles in individuals exposed to atazanavir.

  AIDS (London, England) 20070820

• Review of tipranavir in the treatment of drug-resistant HIV.

  Therapeutics and clinical risk management 20070801

• Electrocardiographic changes in HIV-infected, drug-experienced patients being treated with atazanavir.

  AIDS (London, England) 20070731

• [Insulin resistance in HIV-infected patients receiving long-term therapy with efavirenz, lopinavir/ritonavir and atazanavir].

  Medicina clinica 20070714

• Methadone dosing strategies in HIV-infected injection drug users enrolled in a directly observed therapy program.

  Journal of acquired immune deficiency syndromes (1999) 20070701

• Interindividual variability in the effect of atazanavir and saquinavir on the expression of lymphocyte P-glycoprotein.

  The Journal of antimicrobial chemotherapy 20070701

• Optimal timing and duration of induction therapy for HIV-1 infection.

  PLoS computational biology 20070701

• Antiretroviral therapy-induced liver alterations.

  Current opinion in HIV and AIDS 20070701

• The role of compartment penetration in PI-monotherapy: the Atazanavir-Ritonavir Monomaintenance (ATARITMO) Trial.

  AIDS (London, England) 20070619

• Alopecia associated with ritonavir-boosted atazanavir therapy.

  AIDS (London, England) 20070619

• Variability in non-nucleoside reverse transcriptase and protease inhibitors concentrations among HIV-infected adults in routine clinical practice.

  British journal of clinical pharmacology 20070601

• A novel bis-tetrahydrofuranylurethane-containing nonpeptidic protease inhibitor (PI), GRL-98065, is potent against multiple-PI-resistant human immunodeficiency virus in vitro.

  Antimicrobial agents and chemotherapy 20070601

• Beneficial pharmacokinetic interaction between atazanavir and lopinavir/ritonavir.

  Journal of acquired immune deficiency syndromes (1999) 20070601

• Acute interstitial nephritis of HIV-positive patients under atazanavir and tenofovir therapy in a retrospective analysis of kidney biopsies.

  Virchows Archiv : an international journal of pathology 20070601

• The safety, efficacy, and pharmacokinetic profile of a switch in antiretroviral therapy to saquinavir, ritonavir, and atazanavir alone for 48 weeks and a switch in the saquinavir formulation.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070601

• Efficacy and safety of atazanavir-based highly active antiretroviral therapy in patients with virologic suppression switched from a stable, boosted or unboosted protease inhibitor treatment regimen: the SWAN Study (AI424-097) 48-week results.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070601

• Cushing syndrome and severe adrenal suppression caused by fluticasone and protease inhibitor combination in an HIV-infected adolescent.

  AIDS patient care and STDs 20070601

• Atazanavir-associated nephrolithiasis: cases from the US Food and Drug Administration's Adverse Event Reporting System.

  AIDS (London, England) 20070531

• Atazanavir-containing renal calculi in an HIV-infected patient.

  AIDS (London, England) 20070511

• Buprenorphine assay and plasma concentration monitoring in HIV-infected substance users.

  Journal of pharmaceutical and biomedical analysis 20070509

• Determination of 19 antiretroviral agents in pharmaceuticals or suspected products with two methods using high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501

• Nephrotoxicity associated with antiretroviral therapy in HIV-infected patients.

  Current drug safety 20070501

• Combining resistance and pharmacology for optimum patient care.

  Current opinion in HIV and AIDS 20070501

• Atazanavir in plasma-exchange treatment.

  AIDS (London, England) 20070423

• Safety and efficacy of the HIV-1 integrase inhibitor raltegravir (MK-0518) in treatment-experienced patients with multidrug-resistant virus: a phase II randomised controlled trial.

  Lancet (London, England) 20070414

• An isocratic liquid chromatography method for determining HIV non-nucleoside reverse transcriptase inhibitor and protease inhibitor concentrations in human plasma.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401

• Early virologic rebound in a pilot trial of ritonavir-boosted atazanavir as maintenance monotherapy.

  Journal of acquired immune deficiency syndromes (1999) 20070401

• Influence of liver fibrosis stage on plasma levels of antiretroviral drugs in HIV-infected patients with chronic hepatitis C.

  The Journal of infectious diseases 20070401

• Atazanavir: simplicity and convenience in different scenarios.

  Expert opinion on pharmacotherapy 20070401

• Switching to unboosted atazanavir improves glucose tolerance in highly pretreated HIV-1 infected subjects.

  European journal of endocrinology 20070401

• Pharmaceutical approach to HIV protease inhibitor atazanavir for bioavailability enhancement based on solid dispersion system.

  Biological & pharmaceutical bulletin 20070401

• Antiviral activity and clinical efficacy of atazanavir in HIV-1-infected patients: a review.

  The new microbiologica 20070401

• Impact of modelling intra-subject variability on tests based on non-linear mixed-effects models in cross-over pharmacokinetic trials with application to the interaction of tenofovir on atazanavir in HIV patients.

  Statistics in medicine 20070315

• Prolonged QT interval and torsades de pointes associated with atazanavir therapy.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070315

• High-performance liquid chromatography assay for the determination of the HIV-protease inhibitor tipranavir in human plasma in combination with nine other antiretroviral medications.

  Journal of pharmaceutical and biomedical analysis 20070312

• Modification of tandem mass spectrometric method to permit simultaneous quantification of 17 anti-HIV drugs which include atazanavir and tipranavir.

  Clinica chimica acta; international journal of clinical chemistry 20070301

• Multidrug resistance 1 polymorphisms and trough concentrations of atazanavir and lopinavir in patients with HIV.

  Pharmacogenomics 20070301

• Quality of life in HIV clinical trials: why sexual health must not be ignored.

  PLoS clinical trials 20070301

• Pharmacokinetic interaction between rifampicin and ritonavir-boosted atazanavir in HIV-infected patients.

  HIV medicine 20070301

• Development and validation of a preclinical food effect model.

  Journal of pharmaceutical sciences 20070201

• Modulation of human BCRP (ABCG2) activity by anti-HIV drugs.

  The Journal of antimicrobial chemotherapy 20070201

• Pharmacokinetics of saquinavir with atazanavir or low-dose ritonavir administered once daily (ASPIRE I) or twice daily (ASPIRE II) in seronegative volunteers.

  Journal of clinical pharmacology 20070201

• Monopolizing clinical trial data: implications and trends.

  PLoS medicine 20070201

• Integration of atazanavir into an existing liquid chromatography UV method for protease inhibitors: validation and application.

  Therapeutic drug monitoring 20070201

• Update in HIV care.

  Journal of general internal medicine 20070201

• Genetic factors influencing atazanavir plasma concentrations and the risk of severe hyperbilirubinemia.

  AIDS (London, England) 20070102

• Simultaneous determination of 8 HIV protease inhibitors in human plasma by isocratic high-performance liquid chromatography with combined use of UV and fluorescence detection: amprenavir, indinavir, atazanavir, ritonavir, lopinavir, saquinavir, nelfinavir and M8-nelfinavir metabolite.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070101

• Cost effectiveness of lopinavir/ritonavir compared with atazanavir in antiretroviral-naive patients: modelling the combined effects of HIV and heart disease.

  Clinical drug investigation 20070101

• A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism.

  PLoS medicine 20070101

• A comparison of different protease inhibitors on coronary heart disease risk.

  Connecticut medicine 20070101

• HIV-1 integrase inhibitors are substrates for the multidrug transporter MDR1-P-glycoprotein.

  Retrovirology 20070101

• Renal function in antiretroviral-experienced patients treated with tenofovir disoproxil fumarate associated with atazanavir/ritonavir.

  Antiviral therapy 20070101

• AIDS in the Third World: how to stop the HIV infection?

  Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20070101

• Anti-HIV drugs.

  Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20070101

• Cost effectiveness of lopinavir/ritonavir compared with atazanavir plus ritonavir in antiretroviral-experienced patients in the US.

  Clinical drug investigation 20070101

• Synergistic inhibition of protease-inhibitor-resistant HIV type 1 by saquinavir in combination with atazanavir or lopinavir.

  Antiviral therapy 20070101

• Pharmacokinetics of darunavir (TMC114) and atazanavir during coadministration in HIV-negative, healthy volunteers.

  Drugs in R&D 20070101

• Fast and simultaneous determination of darunavir and eleven other antiretroviral drugs for therapeutic drug monitoring: method development and validation for the determination of all currently approved HIV protease inhibitors and non-nucleoside reverse transcriptase inhibitors in human plasma by liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin, amiodarone, and atazanavir.

  Journal of the American Board of Family Medicine : JABFM 20070101

• Electrospray tandem mass spectroscopic characterisation of 18 antiretroviral drugs and simultaneous quantification of 12 antiretrovirals in plasma.

  Rapid communications in mass spectrometry : RCM 20070101

• A randomized trial evaluating Prosaptide for HIV-associated sensory neuropathies: use of an electronic diary to record neuropathic pain.

  PloS one 20070101

• Validation of the SCID-hu Thy/Liv mouse model with four classes of licensed antiretrovirals.

  PloS one 20070101

• Some HIV antiretrovirals increase oxidative stress and alter chemokine, cytokine or adiponectin production in human adipocytes and macrophages.

  Antiviral therapy 20070101

• Abacavir plasma pharmacokinetics in the absence and presence of atazanavir/ritonavir or lopinavir/ritonavir and vice versa in HIV-infected patients.

  Antiviral therapy 20070101

• An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides.

  PloS one 20070101

• Utilization and spending trends for antiretroviral medications in the U.S. Medicaid program from 1991 to 2005.

  AIDS research and therapy 20070101

• Cost effectiveness of lopinavir/ritonavir tablets compared with atazanavir plus ritonavir in antiretroviral-experienced patients in the UK, France, Italy and Spain.

  Clinical drug investigation 20070101

• Inhibitors of HIV-1 protease: current state of the art 10 years after their introduction. From antiretroviral drugs to antifungal, antibacterial and antitumor agents based on aspartic protease inhibitors.

  Current medicinal chemistry 20070101

• Factors associated with altered pharmacokinetics in substance users and non-substance users receiving lopinavir and atazanavir.

  The American journal on addictions 20070101

• Maraviroc: the evidence for its potential in the management of HIV.

  Core evidence 20070101

• Renal function in patients receiving tenofovir with ritonavir/lopinavir or ritonavir/atazanavir in the HIV Outpatient Study (HOPS) cohort.

  Journal of acquired immune deficiency syndromes (1999) 20061215

• HIV protease inhibitors activate the unfolded protein response and disrupt lipid metabolism in primary hepatocytes.

  American journal of physiology. Gastrointestinal and liver physiology 20061201

• Meeting report. Report from ICAAC.

  AIDS clinical care 20061201

• Atazanavir urolithiasis.

  The New England journal of medicine 20061116

• Influence of atazanavir 200 mg on the intracellular and plasma pharmacokinetics of saquinavir and ritonavir 1600/100 mg administered once daily in HIV-infected patients.

  The Journal of antimicrobial chemotherapy 20061101

• Gilbert's disease and atazanavir: from phenotype to UDP-glucuronosyltransferase haplotype.

  Hepatology (Baltimore, Md.) 20061101

• Variability in non-nucleoside reverse transcriptase and protease inhibitor concentrations among HIV-infected adults in routine clinical practice.

  British journal of clinical pharmacology 20061101

• Metabolic abnormalities in HIV-infected patients: an update.

  Current infectious disease reports 20061101

• Acid suppressive therapy and the effects on protease inhibitors.

  The Annals of pharmacotherapy 20061101

• Does HIV cause cardiovascular disease?

  PLoS medicine 20061101

• Successful treatment with atazanavir and lopinavir/ritonavir combination therapy in protease inhibitor-susceptible and protease inhibitor-resistant HIV-infected patients.

  AIDS patient care and STDs 20061101

• New atazanavir capsule approved.

  AIDS patient care and STDs 20061101

• Suppression of HIV-1 protease inhibitor resistance by phosphonate-mediated solvent anchoring.

  Journal of molecular biology 20061027

• Therapeutic ritonavir-boosted atazanavir plasma concentration and concurrent omeprazole use.

  AIDS (London, England) 20061024

• Atazanavir urinary stones in an HIV-infected patient.

  AIDS (London, England) 20061024

• Simple determination of the HIV protease inhibitor atazanavir in human plasma by high-performance liquid chromatography with UV detection.

  Journal of pharmaceutical and biomedical analysis 20061011

• Response to 'Atazanavir/ritonavir versus lopinavir/ritonavir: equivalent or different efficacy profiles?' by Hill.

  AIDS (London, England) 20061003

• Clinical outcomes associated with concomitant use of atazanavir and proton pump inhibitors.

  The Annals of pharmacotherapy 20061001

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20061001

• Effects of atazanavir/ritonavir and lopinavir/ritonavir on glucose uptake and insulin sensitivity: demonstrable differences in vitro and clinically.

  AIDS (London, England) 20060911

• Change to a once-daily combination including boosted atazanavir in HIV-1-infected children.

  The Pediatric infectious disease journal 20060901

• Clinically relevant pharmacology of neuropsychiatric drugs approved over the last three years: Part II.

  Journal of psychiatric practice 20060901

• An update on HIV-1 antiretroviral resistance.

  Current opinion in HIV and AIDS 20060901

• Management of antiretroviral drug toxicity.

  Current opinion in HIV and AIDS 20060901

• Regimen simplification to atazanavir-ritonavir alone as maintenance antiretroviral therapy after sustained virologic suppression.

  JAMA 20060816

• Further information on the administration of h2-receptor antagonists with atazanavir.

  Journal of acquired immune deficiency syndromes (1999) 20060801

• Liquid chromatographic assay for the non-peptidic protease inhibitor tipranavir in plasma.

  Biomedical chromatography : BMC 20060801

• An update and review of antiretroviral therapy.

  Pharmacotherapy 20060801

• Full validation of an analytical method for the HIV-protease inhibitor atazanavir in combination with 8 other antiretroviral agents and its applicability to therapeutic drug monitoring.

  Therapeutic drug monitoring 20060801

• Pharmacokinetics of saquinavir hard-gel/ritonavir and atazanavir when combined once daily in HIV Type 1-infected individuals administered different atazanavir doses.

  AIDS research and human retroviruses 20060801

• Influence of tenofovir, nevirapine and efavirenz on ritonavir-boosted atazanavir pharmacokinetics in HIV-infected patients.

  European journal of clinical pharmacology 20060701

• A prospective evaluation of the effect of atazanavir on the QTc interval and QTc dispersion in HIV-positive patients.

  HIV medicine 20060701

• [Acute tubulointerstitial nephritis in HIV infection].

  Praxis 20060607

• Can boosted atazanavir induce hyperlipotrophy?

  The Journal of infection 20060601

• Rescue therapy with once-daily atazanavir-based regimens for antiretroviral-experienced HIV-infected patients.

  Journal of acquired immune deficiency syndromes (1999) 20060601

• Antiretroviral drug resistance and routine therapy, Cameroon.

  Emerging infectious diseases 20060601

• Quality assurance program for pharmacokinetic assay of antiretrovirals: ACTG proficiency testing for pediatric and adult pharmacology support laboratories, 2003 to 2004: a requirement for therapeutic drug monitoring.

  Therapeutic drug monitoring 20060601

• HIV protease inhibitor-specific alterations in human adipocyte differentiation and metabolism.

  Obesity (Silver Spring, Md.) 20060601

• Atazanavir and lopinavir/ritonavir: pharmacokinetics, safety and efficacy of a promising double-boosted protease inhibitor regimen.

  AIDS (London, England) 20060512

• Skin rash associated with atazanavir: report of three cases.

  AIDS (London, England) 20060512

• Unexpected improvement of sexual dysfunction during atazanavir therapy.

  AIDS (London, England) 20060512

• Analysis of HIV-1 CRF_01 A/E protease inhibitor resistance: structural determinants for maintaining sensitivity and developing resistance to atazanavir.

  Biochemistry 20060502

• Low incidence of severe liver toxicity in patients receiving antiretroviral combinations including atazanavir.

  The Journal of antimicrobial chemotherapy 20060501

• Ritonavir-boosted atazanavir may be efficacious in HIV-infected patients concurrently receiving omeprazole.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060501

• External validation of atazanavir/ritonavir genotypic score in HIV-1 protease inhibitor-experienced patients.

  Journal of acquired immune deficiency syndromes (1999) 20060501

• A single centre cohort experience with a new once daily antiretroviral drug.

  Postgraduate medical journal 20060501

• Antiretroviral medications associated with elevated blood pressure among patients receiving highly active antiretroviral therapy.

  AIDS (London, England) 20060424

• Critical drug interaction between ritonavir-boosted atazanavir regimen and non-nucleoside reverse transcriptase inhibitors.

  AIDS (London, England) 20060424

• Effect of baseline protease genotype and phenotype on HIV response to atazanavir/ritonavir in treatment-experienced patients.

  AIDS (London, England) 20060404

• Ultra-potent P1 modified arylsulfonamide HIV protease inhibitors: the discovery of GW0385.

  Bioorganic & medicinal chemistry letters 20060401

• Susceptibility to protease inhibitors in HIV-2 primary isolates from patients failing antiretroviral therapy.

  The Journal of antimicrobial chemotherapy 20060401

• Effects of esomeprazole on the pharmacokinetics of atazanavir and fosamprenavir in a patient with human immunodeficiency virus infection.

  Pharmacotherapy 20060401

• The effects of the Roche AMPLICOR HIV-1 MONITOR UltraSensitive Test versions 1.0 and 1.5 viral load assays and plasma collection tube type on determination of response to antiretroviral therapy and the inappropriateness of cross-study comparisons.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20060401

• Susceptibility to antiretroviral drugs of CRF01_AE, CRF02_AG, and subtype C viruses from untreated patients of Africa and Asia: comparative genotypic and phenotypic data.

  AIDS research and human retroviruses 20060401

• Report from the 13th retrovirus conference. Extending the role of atazanavir.

  AIDS clinical care 20060401

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20060401

• New antiretroviral drugs in clinical use.

  Indian journal of pediatrics 20060401

• 96-week comparison of once-daily atazanavir/ritonavir and twice-daily lopinavir/ritonavir in patients with multiple virologic failures.

  AIDS (London, England) 20060321

• Three case reports of a clinical pharmacokinetic interaction with buprenorphine and atazanavir plus ritonavir.

  AIDS (London, England) 20060321

• Inhibition of atazanavir oral absorption by lansoprazole gastric acid suppression in healthy volunteers.

  Pharmacotherapy 20060301

• Lack of interaction between atazanavir and proton pump inhibitors in HIV-infected patients treated with ritonavir-boosted atazanavir.

  Journal of acquired immune deficiency syndromes (1999) 20060301

• Proton pump inhibitor therapy in atazanavir-treated patients: contraindicated?

  Journal of acquired immune deficiency syndromes (1999) 20060301

• Inhibition of HIV-1 replication in human primary cells by a dolabellane diterpene isolated from the marine algae Dictyota pfaffii.

  Planta medica 20060301

• Early clinical experience with atazanavir in treatment-experienced patients.

  Sexual health 20060301

• A monolithic-phase based on-line extraction approach for determination of pharmaceutical components in human plasma by HPLC-MS/MS and a comparison with liquid-liquid extraction.

  Journal of pharmaceutical and biomedical analysis 20060224

• Determination of the novel non-peptidic HIV-protease inhibitor tipranavir by HPLC-UV after solid-phase extraction.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060217

• Simultaneous determination of 16 anti-HIV drugs in human plasma by high-performance liquid chromatography.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060202

• Some PIs have greater impact than others on heart disease. Patients on atazanavir had less heart problems.

  AIDS alert 20060201

• Body fat and other metabolic effects of atazanavir and efavirenz, each administered in combination with zidovudine plus lamivudine, in antiretroviral-naive HIV-infected patients.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060115

• Tenofovir-associated acute and chronic kidney disease: a case of multiple drug interactions.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060115

• Plasma levels of atazanavir and the risk of hyperbilirubinemia are predicted by the 3435C-->T polymorphism at the multidrug resistance gene 1.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20060115

• Human placental transfer of atazanavir: a case report.

  AIDS (London, England) 20060109

• Clinical validation of atazanavir/ritonavir genotypic resistance score in protease inhibitor-experienced patients.

  AIDS (London, England) 20060102

• A case of transient hyperphosphatasemia of infancy and early childhood in an HIV-positive adult possibly related to atazanavir.

  AIDS (London, England) 20060102

• Liquid chromatographic assay for the protease inhibitor atazanavir in plasma.

  Biomedical chromatography : BMC 20060101

• Interaction between atazanavir and fosamprenavir in the treatment of HIV-infected patients.

  Journal of acquired immune deficiency syndromes (1999) 20060101

• Update on HAART in HIV.

  Journal of hepatology 20060101

• Antiviral hepatitis and antiretroviral drug interactions.

  Journal of hepatology 20060101

• Understanding and avoiding antiretroviral adverse events.

  Current pharmaceutical design 20060101

• Ritonavir-boosted atazanavir-lopinavir combination: a pharmacokinetic interaction study of total, unbound plasma and cellular exposures.

  Antiviral therapy 20060101

• Direct and fast determination of antiretroviral drugs by automated online solid-phase extraction-liquid chromatography-tandem mass spectrometry in human plasma.

  Clinical chemistry and laboratory medicine 20060101

• DR_SEQAN: a PC/Windows-based software to evaluate drug resistance using human immunodeficiency virus type 1 genotypes.

  BMC infectious diseases 20060101

• Antiretroviral treatment of HIV infection: Swedish recommendations 2005.

  Scandinavian journal of infectious diseases 20060101

• Atazanavir plasma concentrations vary significantly between patients and correlate with increased serum bilirubin concentrations.

  HIV clinical trials 20060101

• Salvage therapy with atazanavir/ritonavir combined to tenofovir in HIV-infected patients with multiple treatment failures: randomized ANRS 107 trial.

  Antiviral therapy 20060101

• Lopinavir/ritonavir: a review of its use in the management of HIV infection.

  Drugs 20060101

• Virological responses to atazanavir-ritonavir-based regimens: resistance-substitutions score and pharmacokinetic parameters (Reyaphar study).

  Antiviral therapy 20060101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20060101

• Performance of six different ritonavir-boosted protease inhibitor-based regimens in heavily antiretroviral-experienced HIV-infected patients.

  HIV clinical trials 20060101

• Cardiovascular risk in patients with HIV Infection: impact of antiretroviral therapy.

  Drugs 20060101

• Cost to achieve an undetectable viral load using recommended antiretroviral regimens.

  HIV clinical trials 20060101

• Fosamprenavir clinical study meta-analysis in ART-naïve subjects: rare occurrence of virologic failure and selection of protease-associated mutations.

  HIV clinical trials 20060101

• Drug interactions. Is atazanavir best when boosted with ritonavir?

  TreatmentUpdate 20060101

• Drug interactions. Atazanavir and acid-reducing agents.

  TreatmentUpdate 20060101

• Drug interactions. Brecanavir--a new protease inhibitor.

  TreatmentUpdate 20060101

• Drug interactions. Kaletra and atazanavir.

  TreatmentUpdate 20060101

• Switching strategies to improve lipid profile and morphologic changes.

  AIDS reviews 20060101

• Specific HIV protease inhibitors inhibit the ability of HPV16 E6 to degrade p53 and selectively kill E6-dependent cervical carcinoma cells in vitro.

  Antiviral therapy 20060101

• Disease Management - Constructing Optimal NRTI-Based Combinations: Past, Present, and Future.

  Journal of the International AIDS Society 20060101

• Simultaneous determination of HIV protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir in human plasma by high-performance liquid chromatography-tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051227

• Direct comparison of the acute in vivo effects of HIV protease inhibitors on peripheral glucose disposal.

  Journal of acquired immune deficiency syndromes (1999) 20051201

• Allosteric modulation of anti-HIV drug and ferric heme binding to human serum albumin.

  The FEBS journal 20051201

• Use of acid-reducing agents in protease inhibitor-based HAART and the potential for negative treatment outcomes.

  The AIDS reader 20051201

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20051201

• Atazanavir/ritonavir versus lopinavir/ritonavir: equivalent or different efficacy profiles?

  AIDS (London, England) 20051118

• Proton pump inhibitors do not reduce atazanavir concentrations in HIV-infected patients treated with ritonavir-boosted atazanavir.

  AIDS (London, England) 20051104

• In vitro inhibition of UDP glucuronosyltransferases by atazanavir and other HIV protease inhibitors and the relationship of this property to in vivo bilirubin glucuronidation.

  Drug metabolism and disposition: the biological fate of chemicals 20051101

• Rash in an HIV-positive patient.

  HIV medicine 20051101

• Gilbert syndrome and the development of antiretroviral therapy-associated hyperbilirubinemia.

  The Journal of infectious diseases 20051015

• Lack of an effect of atazanavir on steady-state pharmacokinetics of methadone in patients chronically treated for opiate addiction.

  AIDS (London, England) 20051014

• Use of bilirubin as a marker of adherence to atazanavir-based antiretroviral therapy.

  AIDS (London, England) 20051014

• PI monotherapy effective as maintenance.

  AIDS patient care and STDs 20051001

• Comparison of atazanavir with lopinavir/ritonavir in patients with prior protease inhibitor failure: a randomized multinational trial.

  Current medical research and opinion 20051001

• Determination of atazanavir in human plasma using solid-phase extraction and high-performance liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20050915

• Unexpected improvement of sexual dysfunction during atazanavir therapy.

  AIDS (London, England) 20050902

• HIV protease inhibitors activate the unfolded protein response in macrophages: implication for atherosclerosis and cardiovascular disease.

  Molecular pharmacology 20050901

• Therapeutic drug monitoring of atazanavir: surveillance of pharmacotherapy in the clinic.

  British journal of clinical pharmacology 20050901

• Atazanavir inhibits P-glycoprotein and multidrug resistance-associated protein efflux activity.

  Journal of acquired immune deficiency syndromes (1999) 20050815

• Novel P1 chain-extended HIV protease inhibitors possessing potent anti-HIV activity and remarkable inverse antiviral resistance profiles.

  Bioorganic & medicinal chemistry letters 20050801

• Atazanavir trough plasma concentration monitoring in a cohort of HIV-1-positive individuals receiving highly active antiretroviral therapy.

  The Journal of antimicrobial chemotherapy 20050801

• Co-administration of atazanavir with proton-pump inhibitors and H2 blockers.

  Journal of acquired immune deficiency syndromes (1999) 20050801

• Steady-state pharmacokinetics of atazanavir given alone or in combination with saquinavir hard-gel capsules or amprenavir in HIV-1-infected patients.

  European journal of clinical pharmacology 20050801

• Review of atazanavir: a novel HIV protease inhibitor.

  Expert opinion on pharmacotherapy 20050801

• Comparison of HIV type 1 protease inhibitor susceptibility results in viral samples analyzed by phenotypic drug resistance assays and by six resistance algorithms: an analysis of a subpopulation of the CHORUS cohort.

  AIDS research and human retroviruses 20050801

• An Italian approach to postmarketing monitoring: preliminary results from the SCOLTA (Surveillance Cohort Long-Term Toxicity Antiretrovirals) project on the safety of lopinavir/ritonavir.

  Journal of acquired immune deficiency syndromes (1999) 20050701

• Conventional HPLC method used for simultaneous determination of the seven HIV protease inhibitors and nonnucleoside reverse transcription inhibitor efavirenz in human plasma.

  Biological & pharmaceutical bulletin 20050701

• The role of diet, exercise and smoking in dyslipidaemia in HIV-infected patients with lipodystrophy.

  HIV medicine 20050701

• New targets and new drugs in the treatment of HIV.

  Enfermedades infecciosas y microbiologia clinica 20050701

• [New antiretroviral treatment modalities].

  Presse medicale (Paris, France : 1983) 20050604

• Atazanavir: effects on P-glycoprotein transport and CYP3A metabolism in vitro.

  Drug metabolism and disposition: the biological fate of chemicals 20050601

• Switching to atazanavir improves metabolic disorders in antiretroviral-experienced patients with severe hyperlipidemia.

  Journal of acquired immune deficiency syndromes (1999) 20050601

• Simultaneous quantitative assay of atazanavir and 6 other HIV protease inhibitors by isocratic reversed-phase liquid chromatography in human plasma.

  Therapeutic drug monitoring 20050601

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050601

• Intracellular measurements of anti-HIV drugs indinavir, amprenavir, saquinavir, ritonavir, nelfinavir, lopinavir, atazanavir, efavirenz and nevirapine in peripheral blood mononuclear cells by liquid chromatography coupled to tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050525

• Lipodystrophy is associated with a low rate of treatment failure in HIV-positive patients switched to atazanavir.

  Journal of acquired immune deficiency syndromes (1999) 20050501

• Impact of acid-suppressive therapy on virologic response to atazanavir-based regimens in antiretroviral-experienced patients: a case series.

  Journal of acquired immune deficiency syndromes (1999) 20050501

• Emerging anti-HIV drugs.

  Expert opinion on emerging drugs 20050501

• [Current status of HIV protease inhibitors].

  Yao xue xue bao = Acta pharmaceutica Sinica 20050501

• Atazanavir plus ritonavir or saquinavir, and lopinavir/ritonavir in patients experiencing multiple virological failures.

  AIDS (London, England) 20050429

• [New data on atazanavir/r]].

  MMW Fortschritte der Medizin 20050425

• Atazanavir: a novel inhibitor of HIV-protease in haemodialysis.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050401

• Simple and simultaneous determination of the hiv-protease inhibitors amprenavir, atazanavir, indinavir, lopinavir, nelfinavir, ritonavir and saquinavir plus M8 nelfinavir metabolite and the nonnucleoside reverse transcriptase inhibitors efavirenz and nevirapine in human plasma by reversed-phase liquid chromatography.

  Therapeutic drug monitoring 20050401

• FDA notifications. BMS issues letter about omeprazole.

  AIDS alert 20050401

• Insulin resistance, HIV infection, and anti-HIV therapies.

  The AIDS reader 20050401

• Metabolic syndrome and cardiovascular disease in patients with human immunodeficiency virus.

  The American journal of medicine 20050401

• Atazanavir affects saquinavir.

  AIDS patient care and STDs 20050401

• Evaluation of atazanavir Ctrough, atazanavir genotypic inhibitory quotient, and baseline HIV genotype as predictors of a 24-week virological response in highly drug-experienced, HIV-infected patients treated with unboosted atazanavir.

  The new microbiologica 20050401

• Design of HIV-1 protease inhibitors active on multidrug-resistant virus.

  Journal of medicinal chemistry 20050324

• Lack of interaction between atazanavir and lansoprazole.

  AIDS (London, England) 20050324

• Impact of dyslipidemia associated with Highly Active Antiretroviral Therapy (HAART) on cardiovascular risk and life expectancy.

  The American journal of cardiology 20050301

• Atazanavir not to be used with proton pump inhibitors.

  AIDS patient care and STDs 20050201

• Avoid PPIs with atazanavir.

  AIDS clinical care 20050201

• Atazanavir plus ritonavir or saquinavir, and lopinavir/ritonavir in patients experiencing multiple virological failures.

  AIDS (London, England) 20050128

• Atazanavir for treatment of HIV infection in clinical routine: efficacy, pharmacokinetics and safety.

  European journal of medical research 20050128

• Substituting abacavir for hyperlipidemia-associated protease inhibitors in HAART regimens improves fasting lipid profiles, maintains virologic suppression, and simplifies treatment.

  BMC infectious diseases 20050101

• Boosted Reyataz comparable to Kaletra.

  AIDS patient care and STDs 20050101

• Changes in lipids over twelve months after initiating protease inhibitor therapy among persons treated for HIV/AIDS.

  Lipids in health and disease 20050101

• Atazanavir: the advent of a new generation of more convenient protease inhibitors.

  HIV clinical trials 20050101

• The steady-state pharmacokinetics of nelfinavir in combination with tenofovir in HIV-infected patients.

  Antiviral therapy 20050101

• Highly active antiretroviral therapy: current state of the art, new agents and their pharmacological interactions useful for improving therapeutic outcome.

  Current pharmaceutical design 20050101

• Drug-drug interactions and the pharmacotherapy of HIV infection.

  Topics in HIV medicine : a publication of the International AIDS Society, USA 20050101

• Clinical pharmacokinetics and summary of efficacy and tolerability of atazanavir.

  Clinical pharmacokinetics 20050101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050101

• Quantification of antiretroviral drugs in dried blood spot samples by means of liquid chromatography/tandem mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20050101

• Atazanavir: a review of its use in the management of HIV infection.

  Drugs 20050101

• Anti-HIV agents. Kaletra + atazanavir.

  TreatmentUpdate 20050101

• Anti-HIV agents. Atazanavir vs. Kaletra.

  TreatmentUpdate 20050101

• New Antiretroviral Therapies for Pediatric HIV Infection.

  The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG 20050101

• Determination of atazanavir and other antiretroviral drugs (indinavir, amprenavir, nelfinavir and its active metabolite M8, saquinavir, ritonavir, lopinavir, nevirapine and efavirenz) plasma levels by high performance liquid chromatography with UV detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

• Atazanavir for the treatment of human immunodeficiency virus infection.

  Pharmacotherapy 20041201

• Reyataz may cause EKG abnormality.

  AIDS patient care and STDs 20041201

• Improved structure-activity relationship analysis of HIV-1 protease inhibitors using interaction kinetic data.

  Journal of medicinal chemistry 20041118

• The effects of HIV protease inhibitors atazanavir and lopinavir/ritonavir on insulin sensitivity in HIV-seronegative healthy adults.

  AIDS (London, England) 20041105

• Pharmacologic perspectives for once-daily antiretroviral therapy.

  The Annals of pharmacotherapy 20041101

• Acute interstitial nephritis associated with atazanavir, a new protease inhibitor.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20041101

• Atazanavir: A novel once-daily protease inhibitor.

  Drugs of today (Barcelona, Spain : 1998) 20041101

• [Therapeutic strategies for HIV infection: clinical approach with boost antiproteases in adults].

  Medecine et maladies infectieuses 20041101

• Determination of the new HIV-protease inhibitor atazanavir by liquid chromatography after solid-phase extraction.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041015

• Pseudoaneurysm of the femoral artery in a HIV-infected man.

  European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 20041001

• Atazanavir.

  The Annals of pharmacotherapy 20041001

• Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naive patients infected with HIV-1.

  PLoS medicine 20041001

• Binding of anti-HIV drugs to human serum albumin.

  IUBMB life 20041001

• HIV-chemotherapy and -prophylaxis: new drugs, leads and approaches.

  The international journal of biochemistry & cell biology 20040901

• Recent changes to FDA-approved labeling.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040901

• New dosing regimen for atazanavir.

  AIDS patient care and STDs 20040901

• Management of HIV-infected patients with multidrug-resistant virus.

  Current HIV/AIDS reports 20040901

• Comparison of once-daily atazanavir with efavirenz, each in combination with fixed-dose zidovudine and lamivudine, as initial therapy for patients infected with HIV.

  Journal of acquired immune deficiency syndromes (1999) 20040815

• Resistance to HIV protease inhibitors: mechanisms and clinical consequences.

  Current drug metabolism 20040801

• Acute hepatic cytolysis in an HIV-infected patient taking atazanavir.

  AIDS (London, England) 20040723

• Atazanavir: a new protease inhibitor to treat HIV infection.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040701

• Atazanavir enhances saquinavir hard-gel concentrations in a ritonavir-boosted once-daily regimen.

  AIDS (London, England) 20040618

• Antiviral drugs in current clinical use.

  Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20040601

• Atazanavir: new option for treatment of HIV infection.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040601

• Long-term efficacy and safety of atazanavir with stavudine and lamivudine in patients previously treated with nelfinavir or atazanavir.

  Journal of acquired immune deficiency syndromes (1999) 20040601

• The influence of protease inhibitor resistance profiles on selection of HIV therapy in treatment-naive patients.

  Antiviral therapy 20040601

• [Recent progress in anti-HIM-1 research].

  Uirusu 20040601

• Simultaneous quantification of the new HIV protease inhibitors atazanavir and tipranavir in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040525

• Identification of I50L as the signature atazanavir (ATV)-resistance mutation in treatment-naive HIV-1-infected patients receiving ATV-containing regimens.

  The Journal of infectious diseases 20040515

• [New treatment options for HIV-infected patients].

  Deutsche medizinische Wochenschrift (1946) 20040507

• Does atazanavir cause lipodystrophy?

  Journal of HIV therapy 20040501

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20040501

• [Simplified HIV therapy. Atazanavir: the first protease inhibitor with once daily administration].

  MMW Fortschritte der Medizin 20040426

• [Long-term tolerance. Favorable lipid profile--favorable effect on development of lipodystrophy?].

  MMW Fortschritte der Medizin 20040426

• [Interview with Professor Jürgen Rockstroh, director of the Bonn University Clinic. Atazanavir in general practice].

  MMW Fortschritte der Medizin 20040426

• [Good experiences with saquinavir. Double boosting of protease inhibitors gains significance].

  MMW Fortschritte der Medizin 20040426

• [Atazanavir protects lipid metabolism. New PI with favorable metabolic profile].

  MMW Fortschritte der Medizin 20040426

• Regression of lipodystrophy in HIV-infected patients under therapy with the new protease inhibitor atazanavir.

  AIDS (London, England) 20040409

• Cross-resistance patterns among HIV protease inhibitors.

  AIDS patient care and STDs 20040401

• Atazanavir (Reyataz): new recommendations if combined with tenofovir (Viread) -- and warning on Viagra, Cialis, and Levitra.

  AIDS treatment news 20040326

• Optimizing dosing strategies for the combination of atazanavir plus saquinavir.

  AIDS (London, England) 20040305

• Drug-induced liver injury associated with antiretroviral therapy that includes HIV-1 protease inhibitors.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20040301

• Kinetic and thermodynamic characterization of HIV-1 protease inhibitors.

  Journal of molecular recognition : JMR 20040101

• New drugs of 2003.

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  International journal of STD & AIDS 20031001

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