201481-37-0 | Fmoc-Allo-Thr(tBu)-OH

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$13.00	$9.00
250mg	97%	in stock	$16.00	$11.00
1g	97%	in stock	$19.00	$14.00
10g	97%	in stock	$120.00	$84.00
25g	97%	in stock	$281.00	$197.00

Description

• Catalog Number: AB10533
• Chemical Name: Fmoc-Allo-Thr(tBu)-OH
• CAS Number: 201481-37-0
• Molecular Formula: C23H27NO5
• Molecular Weight: 397.4642
• MDL Number: MFCD00237371
• SMILES: O=C(N[C@@H]([C@@H](OC(C)(C)C)C)C(=O)O)OCC1c2ccccc2c2c1cccc2

Computed Properties

• Complexity: 564
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 29
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 8
• XLogP3: 4

Upstream Synthesis Route

Fmoc-Allo-Thr(tBu)-OH is a versatile amino acid derivative commonly used in chemical synthesis for the preparation of peptide and protein molecules with specific structural properties. This molecule serves as a key building block in solid-phase peptide synthesis, allowing for the incorporation of the allo-threonine (Allo-Thr) amino acid with t-butyl side-chain protection.The Fmoc (9-fluorenylmethoxycarbonyl) group acts as a temporary protecting group for the amino group of the allo-threonine residue, ensuring selective reactivity during peptide assembly steps. The t-butyl (tBu) protection on the hydroxyl group of allo-threonine provides stability and prevents undesired side reactions, enabling precise manipulation of the amino acid sequence in the peptide chain.By utilizing Fmoc-Allo-Thr(tBu)-OH in chemical synthesis, researchers can tailor the properties and functions of peptides and proteins for various applications, including drug development, structural biology studies, and materials science research. This amino acid derivative's strategic placement within the peptide sequence can influence the overall structure, stability, and biological activity of the final molecule, making it an essential tool in the field of peptide chemistry.