2030-63-9 | Clofazimine

Availability
Typically In Stock

Description

• Catalog Number: AI44554
• Chemical Name: Clofazimine
• CAS Number: 2030-63-9
• Molecular Formula: C27H22Cl2N4
• Molecular Weight: 473.3964
• MDL Number: MFCD00056793
• SMILES: Clc1ccc(cc1)Nc1cc2nc3ccccc3n(c2c/c/1=NC(C)C)c1ccc(cc1)Cl

Computed Properties

• Complexity: 829
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 33
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 7.1

Literature

• Supramolecular strategy for reducing the cardiotoxicity of bedaquiline without compromising its antimycobacterial efficacy.

  Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180901

• Why are most phospholipidosis inducers also hERG blockers?

  Archives of toxicology 20171201

• State-dependent blocking mechanism of Kv 1.3 channels by the antimycobacterial drug clofazimine.

  British journal of pharmacology 20151101

• Activity of linezolid-containing regimens against multidrug-resistant tuberculosis in mice.

  International journal of antimicrobial agents 20140201

• Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain.

  Journal of natural products 20131122

• A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.

  Toxicological sciences : an official journal of the Society of Toxicology 20131101

• FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1.

  Chemico-biological interactions 20130905

• Assessment of clofazimine activity in a second-line regimen for tuberculosis in mice.

  American journal of respiratory and critical care medicine 20130901

• In vitro synergy between clofazimine and amikacin in treatment of nontuberculous mycobacterial disease.

  Antimicrobial agents and chemotherapy 20121201

• Clofazimine in the treatment of multidrug-resistant tuberculosis.

  Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20121101

• The pharmacokinetics and pharmacodynamics of pulmonary Mycobacterium avium complex disease treatment.

  American journal of respiratory and critical care medicine 20120915

• In vitro and in vivo activity of clofazimine against Mycobacterium tuberculosis persisters.

  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20120801

• New drugs for the treatment of tuberculosis: hope and reality.

  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20120801

• Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells.

  EMBO molecular medicine 20120701

• Cheilitis granulomatosa (Miescher granulomatous macrocheilitis) with trisomy 21.

  Dermatology online journal 20120615

• Atypical Hansen's disease presenting as florid verrucous plaques on the lower extremities: a case report.

  International journal of dermatology 20120601

• Dapsone induced eosinophilic pneumonia.

  European annals of allergy and clinical immunology 20120601

• Synthesis and anti-tubercular activity of novel alkyl substituted riminophenazine derivatives.

  Yao xue xue bao = Acta pharmaceutica Sinica 20120601

• A comprehensive review of current treatments for granulomatous cheilitis.

  The British journal of dermatology 20120501

• Clofazimine-induced enteropathy in treatment-resistant nodular vasculitis.

  The Australasian journal of dermatology 20120501

• Systematic evaluation of structure-activity relationships of the riminophenazine class and discovery of a C2 pyridylamino series for the treatment of multidrug-resistant tuberculosis.

  Molecules (Basel, Switzerland) 20120417

• A case of leprosy mistaken for cutaneous sarcoidosis.

  Acta dermato-venereologica 20120301

• Florid reactive periostitis ossificans of long bones and digits associated with reaction in a patient with leprosy.

  Leprosy review 20120301

• Anaplastic large cell lymphoma and lepromatous leprosy: a rare coexistence.

  Leprosy review 20120301

• Facial reversal reaction: a dermatological emergency.

  The Journal of dermatology 20120201

• Clofazimine: current status and future prospects.

  The Journal of antimicrobial chemotherapy 20120201

• Drug susceptibility testing and pharmacokinetics question current treatment regimens in Mycobacterium simiae complex disease.

  International journal of antimicrobial agents 20120201

• Use of the polymerase chain reaction to detect Mycobacterium leprae in urine.

  Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20120201

• Successful treatment of granulomatous cheilitis with adalimumab.

  International journal of dermatology 20120101

• Mycobacterium riyadhense pulmonary infection, France and Bahrain.

  Emerging infectious diseases 20120101

• Rapid evaluation in whole blood culture of regimens for XDR-TB containing PNU-100480 (sutezolid), TMC207, PA-824, SQ109, and pyrazinamide.

  PloS one 20120101

• Inhibition of angiogenesis as a new therapeutic target in the treatment of lepromatous leprosy.

  Clinical, cosmetic and investigational dermatology 20120101

• Trends in tropical medicine research in India.

  Indian journal of pharmacology 20120101

• Drug-resistant tuberculosis: Study of clinical practices of chest physicians, Maharashtra, India.

  Lung India : official organ of Indian Chest Society 20120101

• Skin manifestations of inflammatory bowel disease.

  Frontiers in physiology 20120101

• Peptides Derived from Mycobacterium leprae ML1601c Discriminate between Leprosy Patients and Healthy Endemic Controls.

  Journal of tropical medicine 20120101

• Elimination of leprosy & possibility of eradication - the Indian scenario.

  The Indian journal of medical research 20120101

• Hansen's disease (Leprosy): current and future pharmacotherapy and treatment of disease-related immunologic reactions.

  Pharmacotherapy 20120101

• Early results of systematic drug susceptibility testing in pulmonary tuberculosis retreatment cases in Cameroon.

  BMC research notes 20120101

• Ashy dermatosis: a controversial entity.

  Indian journal of dermatology 20120101

• Extra-pulmonary primary multidrug-resistant tubercular lymphadenitis in an HIV negative patient.

  BMJ case reports 20120101

• Synergistic Antimycobacterial Actions of Knowltonia vesicatoria (L.f) Sims.

  Evidence-based complementary and alternative medicine : eCAM 20120101

• Multidrug and extensively drug-resistant tuberculosis management: Evidences and controversies.

  Lung India : official organ of Indian Chest Society 20120101

• Dapsone-induced neutropenia with invasive pulmonary aspergillosis.

  Lung India : official organ of Indian Chest Society 20120101

• Pharmacotherapy for multidrug resistant tuberculosis.

  Journal of pharmacology & pharmacotherapeutics 20120101

• Human immunodeficiency virus and leprosy coinfection: challenges in resource-limited setups.

  Case reports in medicine 20120101

• Lobomycosis.

  Clinics in dermatology 20120101

• Granzyme B-induced neurotoxicity is mediated via activation of PAR-1 receptor and Kv1.3 channel.

  PloS one 20120101

• Macrophages sequester clofazimine in an intracellular liquid crystal-like supramolecular organization.

  PloS one 20120101

• Cutaneous lupus erythematosus: update of therapeutic options part II.

  Journal of the American Academy of Dermatology 20111201

• Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

  PLoS computational biology 20111201

• Treatment and chemoprophylaxis for paratuberculosis.

  The Veterinary clinics of North America. Food animal practice 20111101

• Mycobacterium doricum osteomyelitis and soft tissue infection.

  Emerging infectious diseases 20111101

• Molecular imaging of intracellular drug-membrane aggregate formation.

  Molecular pharmaceutics 20111003

• Evaluation of multi-drug therapy for leprosy in the United States using daily rifampin.

  Southern medical journal 20111001

• Does clofazimine prevent erythema nodosum leprosum (ENL) in leprosy? A retrospective study, comparing the experience of multibacillary patients receiving either 12 or 24 months WHO-MDT.

  Leprosy review 20110901

• Chromoblastomycosis in a case of borderline lepromatous leprosy with recurrent type II lepra reaction.

  Leprosy review 20110901

• Synergistic drug combinations for tuberculosis therapy identified by a novel high-throughput screen.

  Antimicrobial agents and chemotherapy 20110801

• [In vitro activities of clofazimine against different drug-resistant types of Mycobacterium tuberculosis].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20110801

• An unusual cause of small-intestine mucosal pigmentation.

  Gastrointestinal endoscopy 20110601

• New and improved diagnostics for detection of drug-resistant pulmonary tuberculosis.

  Current opinion in pulmonary medicine 20110501

• Interferon-gamma receptor-1 gene promoter polymorphisms and susceptibility to leprosy in children of a single family.

  The American journal of tropical medicine and hygiene 20110405

• Wild-type distributions of seven oral second-line drugs against Mycobacterium tuberculosis.

  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20110401

• A phase two randomised controlled double blind trial of high dose intravenous methylprednisolone and oral prednisolone versus intravenous normal saline and oral prednisolone in individuals with leprosy type 1 reactions and/or nerve function impairment.

  PLoS neglected tropical diseases 20110401

• Reduction of clofazimine by mycobacterial type 2 NADH:quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species.

  The Journal of biological chemistry 20110325

• Severe refractory erythema nodosum leprosum successfully treated with the tumor necrosis factor inhibitor etanercept.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20110301

• Mycobacterium lentiflavum in drinking water supplies, Australia.

  Emerging infectious diseases 20110301

• Adverse effects of multi-drug therapy in leprosy, a two years' experience (2006-2008) in tertiary health care centre in the tribal region of Chhattisgarh State (Bastar, Jagdalpur).

  Leprosy review 20110301

• Detection of mutations in folp1, rpoB and gyrA genes of M. leprae by PCR- direct sequencing--a rapid tool for screening drug resistance in leprosy.

  Leprosy review 20110301

• Relapse study in smear positive multibacillary (MB) leprosy after 1 year WHO-multi-drug therapy (MDT) in Cebu, Philippines.

  Leprosy review 20110301

• Longitudinal ocular survey of 202 Filipino patients with multi-bacillary (MB) leprosy treated with 2 year WHO-multiple drug therapy.

  The Southeast Asian journal of tropical medicine and public health 20110301

• Leprosy in transplant recipients: report of a case after liver transplantation and review of the literature.

  Transplant infectious disease : an official journal of the Transplantation Society 20110201

• Segniliparus rugosus-associated bronchiolitis in California sea lion.

  Emerging infectious diseases 20110201

• [Childhood leprosy: Report of a case].

  Dermatology online journal 20110115

• Consensus Conference on Clinical Practice in Chronic GVHD: Second-Line Treatment of Chronic Graft-versus-Host Disease.

  Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110101

• HIV-Associated Tuberculosis in the Newborn and Young Infant.

  International journal of pediatrics 20110101

• Current and emerging drugs for the treatment of inflammatory bowel disease.

  Drug design, development and therapy 20110101

• Size and usage patterns of private TB drug markets in the high burden countries.

  PloS one 20110101

• Necrobiosis lipoidica: early diagnosis and treatment with tacrolimus.

  Case reports in dermatology 20110101

• Crystalline deposition in the cornea and conjunctiva secondary to long-term clofazimine therapy in a leprosy patient.

  Indian journal of ophthalmology 20110101

• Genetic approach for the fast discovery of phenazine producing bacteria.

  Marine drugs 20110101

• Confusion and slurred speech in a 34-year-old woman from India.

  Frontiers in neurology 20110101

• Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole.

  Molecular systems biology 20110101

• Lupus miliaris disseminatus faciei with unusual distribution of lesions.

  Indian journal of dermatology 20110101

• Co-existent acquired perforating collagenosis and lepromatous leprosy with erythema nodosum leprosum: response to treatment.

  Indian journal of dermatology, venereology and leprology 20110101

• Pyoderma gangrenosum: variation in clinical presentation at different ages.

  Indian journal of dermatology 20110101

• Tuberculosis in Birds: Insights into the Mycobacterium avium Infections.

  Veterinary medicine international 20110101

• Compression therapy: an adjuvant treatment for orofacial granulomatosis in Melkersson-Rosenthal syndrome?

  European journal of dermatology : EJD 20110101

• Treatment of tuberculosis in a region with high drug resistance: outcomes, drug resistance amplification and re-infection.

  PloS one 20110101

• Identification of novel functional inhibitors of acid sphingomyelinase.

  PloS one 20110101

• Antimicrobial therapy for the treatment of opportunistic infections in HIV/AIDS patients: a critical appraisal.

  HIV/AIDS (Auckland, N.Z.) 20110101

• Ulcerative pyoderma gangrenosum in mixed connective tissue disorder: a rare association and role of azathioprine in the management.

  Indian journal of dermatology 20110101

• Elimination of leprosy as a public health problem by 2000 AD: an epidemiological perspective.

  The Pan African medical journal 20110101

• Neglected tropical diseases and the millennium development goals: why the 'other diseases' matter: reality versus rhetoric.

  Parasites & vectors 20110101

• Nanosuspension: An approach to enhance solubility of drugs.

  Journal of advanced pharmaceutical technology & research 20110101

• Drug-resistant tuberculosis: emerging treatment options.

  Clinical pharmacology : advances and applications 20110101

• Arthritis in leprosy.

  Rheumatology (Oxford, England) 20101201

• Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.

  Toxicological sciences : an official journal of the Society of Toxicology 20101201

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Disseminated superficial porokeratosis and pyoderma gangrenosum.

  Dermatology online journal 20101015

• Short, highly effective, and inexpensive standardized treatment of multidrug-resistant tuberculosis.

  American journal of respiratory and critical care medicine 20100901

• Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis.

  The Lancet. Infectious diseases 20100901

• [A study on the activity of clofazimine with antituberculous drugs against Mycobacterium tuberculosis].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20100901

• Minocycline is effective and cosmetically preferred to clofazimine by leprosy patients in New York.

  Journal of drugs in dermatology : JDD 20100801

• Capreomycin-induced optic neuritis in a case of multidrug resistant pulmonary tuberculosis.

  Indian journal of pharmacology 20100801

• Colloid formation by drugs in simulated intestinal fluid.

  Journal of medicinal chemistry 20100527

• Clofazimine, an antimycobacterial with potent in vitro and in vivo leishmanicidal activity, is ineffective against cutaneous Leishmania major infection in humans.

  Journal of the American Academy of Dermatology 20100501

• High efficacy of clofazimine and its synergistic effect with amikacin against rapidly growing mycobacteria.

  International journal of antimicrobial agents 20100401

• Long-term antibiotic treatment for Crohn's disease: systematic review and meta-analysis of placebo-controlled trials.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20100215

• Plasma levels of chemokines during leprosy specific treatment.

  Acta tropica 20100201

• In vitro drug susceptibility of 2275 clinical non-tuberculous Mycobacterium isolates of 49 species in The Netherlands.

  International journal of antimicrobial agents 20100201

• Melkersson-Rosenthal syndrome in a patient with tubercular panuveitis.

  Indian journal of ophthalmology 20100101

• Sweet Syndrome due to Myelodysplastic Syndrome: Possible Therapeutic Role of Intravenous Immunoglobulin in Addition to Standard Treatment.

  Advances in hematology 20100101

• Optimal management of cytomegalovirus retinitis in patients with AIDS.

  Clinical ophthalmology (Auckland, N.Z.) 20100101

• Suspected intestinal tuberculosis might be Crohn's disease.

  Case reports in medicine 20100101

• Lobomycosis.

  Anais brasileiros de dermatologia 20100101

• Concomittant pulmonary tuberculosis and borderline leprosy with type-II lepra reaction in single patient.

  Lung India : official organ of Indian Chest Society 20100101

• Acute febrile neutrophilic dermatosis (Sweet's syndrome) in a child, associated with a rotavirus infection: a case report.

  Journal of medical case reports 20100101

• Identification of novel inhibitors of dietary lipid absorption using zebrafish.

  PloS one 20100101

• Methemoglobinemia and dapsone levels in patients with leprosy.

  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20100101

• Novel rodent models for macular research.

  PloS one 20100101

• Leprosy therapy, past and present: can we hope to eliminate it?

  Indian journal of dermatology 20100101

• Leprosy in a renal transplant recipient: review of the literature.

  Transplant infectious disease : an official journal of the Transplantation Society 20091201

• Nonpruritic erythematous plaques.

  The Journal of family practice 20091201

• Discovery of small molecule inhibitors of protein-protein interactions using combined ligand and target score normalization.

  Journal of chemical information and modeling 20091201

• Interventions for erythema nodosum leprosum. A Cochrane review.

  Leprosy review 20091201

• Treatment of recurrent aphthous stomatitis with clofazimine.

  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20091101

• Long-term relapse risk of multibacillary leprosy after completion of 2 years of multiple drug therapy (WHO-MDT) in Cebu, Philippines.

  The American journal of tropical medicine and hygiene 20091101

• Identification of potent chemotypes targeting Leishmania major using a high-throughput, low-stringency, computationally enhanced, small molecule screen.

  PLoS neglected tropical diseases 20091101

• Response of ulcerated necrobiosis lipoidica to clofazimine.

  Acta dermato-venereologica 20091101

• Lobomycosis. Literature review and future perspectives.

  Actas dermo-sifiliograficas 20091101

• Drugs for discoid lupus erythematosus.

  The Cochrane database of systematic reviews 20091007

• Persistent swelling of lip.

  Indian pediatrics 20091001

• Lucio's phenomenon: a report of three cases seen in Johor, Malaysia.

  International journal of dermatology 20090901

• Use of clofazimine in dermatology.

  Journal of drugs in dermatology : JDD 20090901

• Two patients with leprosy and the sudden appearance of inflammation in the skin and new sensory loss.

  PLoS neglected tropical diseases 20090901

• [Tissue distribution and deposition of clofazimine in mice following oral administration of isoniazid].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20090901

• Comparison of three methods for susceptibility testing of Mycobacterium avium subsp. paratuberculosis to 11 antimicrobial drugs.

  The Journal of antimicrobial chemotherapy 20090801

• A comparative clinical trial in multibacillary leprosy with long-term relapse rates of four different multidrug regimens.

  The American journal of tropical medicine and hygiene 20090801

• Type 1 leprosy reversal reaction treated with topical tacrolimus along with systemic corticosteroids.

  Indian journal of medical sciences 20090801

• Interventions for erythema nodosum leprosum.

  The Cochrane database of systematic reviews 20090708

• Twenty five years follow up of MB leprosy patients retreated with a modified MDT regimen after a full course of dapsone mono-therapy.

  Leprosy review 20090601

• Spatial distribution of leprosy in the Amazon region of Brazil.

  Emerging infectious diseases 20090401

• Agranulocytosis induced by multidrug therapy in leprosy treatment: a case report.

  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20090401

• Lest we forget Hansen's disease (leprosy): an unusual presentation with an acute onset of inflammatory polyarthritis and the rheumatology experience.

  International journal of rheumatic diseases 20090401

• [Persistent type 2 lepra reaction (erythema nodosum) and clofazimine-induced lethal enteropathy].

  Biomedica : revista del Instituto Nacional de Salud 20090301

• Nanoaggregates of a random amphiphilic polyanion to carry water-insoluble clofazimine in neutral aqueous media.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090215

• Leprosy: not always an easy diagnosis and often a management challenge.

  The Australasian journal of dermatology 20090201

• Hansen's disease in Portugal: multibacillary patients treated between 1988 and 2003.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20090101

• Autochthonous leprosy in metropolitan France presenting with a diffuse infiltration of the face and febrile illness.

  International journal of dermatology 20090101

• Single lesion multibacillary leprosy, a treatment enigma: a case report.

  Journal of medical case reports 20090101

• Question: Can you identify this condition? Tuberculoid leprosy.

  Canadian family physician Medecin de famille canadien 20090101

• Accidental Jorge Lobo's disease in a worker dealing with Lacazia loboi infected mice: a case report.

  Journal of medical case reports 20090101

• Granulomatous cheilitis: a condition that merits inclusion in the differential diagnosis of angioedema.

  Journal of investigational allergology & clinical immunology 20090101

• Relapse of leprosy presenting as nodular lymph node swelling.

  Indian journal of dermatology, venereology and leprology 20090101

• Monensin causes dose dependent inhibition of Mycobacterium avium subspecies paratuberculosis in radiometric culture.

  Gut pathogens 20090101

• Extensively drug resistance (XDR) tb is not always fatal.

  The Indian journal of tuberculosis 20090101

• Mycobacterium avium subspecies paratuberculosis, Crohn's disease and the Doomsday scenario.

  Gut pathogens 20090101

• Neutrophilic dermatoses: a review of current treatment options.

  American journal of clinical dermatology 20090101

• ['Rheumatoid arthritis' in a Surinamese man: leprosy].

  Nederlands tijdschrift voor geneeskunde 20090101

• Integration of leprosy elimination into primary health care in orissa, India.

  PloS one 20090101

• Drug usage evaluation of dapsone.

  Indian journal of pharmaceutical sciences 20090101

• Annular vesiculobullous eruptions in type 2 reaction in borderline lepromatous leprosy: a case report.

  Indian journal of leprosy 20090101

• Rhinoscleroma: a French national retrospective study of epidemiological and clinical features.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081201

• A retrospective study of the effect of modified multi-drug therapy in Nepali leprosy patients following the development of adverse effects due to dapsone.

  Leprosy review 20081201

• Dapsone-induced haemolytic anaemia, hepatitis and agranulocytosis in a leprosy patient with normal glucose-6-phosphate-dehydrogenase activity.

  Leprosy review 20081201

• Immune response following miltefosine therapy in a patient with post-kala-azar dermal leishmaniasis.

  Transactions of the Royal Society of Tropical Medicine and Hygiene 20081101

• [Sensory-motor neuropathy: a slow and misleading case of leprosy].

  Revue neurologique 20081101

• Mycobacterium haemophilum infection after alemtuzumab treatment.

  Emerging infectious diseases 20081101

• Type I reaction in a borderline leprosy case successfully treated with multidrug therapy and ofloxacin.

  International journal of dermatology 20081001

• [Activities of clofazimine against Mycobacterium tuberculosis in vitro and in vivo].

  Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20081001

• Tuberculoid leprosy and Type 1 lepra reaction.

  Travel medicine and infectious disease 20080901

• Does clofazimine (B663) reach Mycobacterium leprae persisting in Schwann cells and endothelial cells of endoneurial blood vessels in peripheral nerves?

  Microscopy research and technique 20080801

• Three indigenous cases of leprosy in the Mississippi delta.

  Southern medical journal 20080601

• Antimycobacterial therapy for Crohn's disease: a reanalysis.

  The Lancet. Infectious diseases 20080601

• International open trial of uniform multi-drug therapy regimen for 6 months for all types of leprosy patients: rationale, design and preliminary results.

  Tropical medicine & international health : TM & IH 20080501

• Activity of twelve second-line antimicrobial agents against Mycobacterium tuberculosis in Taiwan.

  Journal of chemotherapy (Florence, Italy) 20080401

• [Polyarthritis and papular eruption revealing leprosy].

  La Revue de medecine interne 20080301

• Mycobacterium xenopi clinical relevance and determinants, the Netherlands.

  Emerging infectious diseases 20080301

• Clofazimine.

  Tuberculosis (Edinburgh, Scotland) 20080301

• Early diagnosis of disseminated Mycobacterium genavense infection.

  Emerging infectious diseases 20080201

• [Hansen's disease: case report and review of literature].

  Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia 20080201

• [Melkersson-Rosenthal syndrome treated with clofazimine].

  Ugeskrift for laeger 20080114

• Adjuvant interferon gamma in patients with pulmonary atypical Mycobacteriosis: a randomized, double-blind, placebo-controlled study.

  BMC infectious diseases 20080101

• Mycobacterium chelonae keratitis in a patient with Sjögren's syndrome.

  European journal of ophthalmology 20080101

• The in vitro antitumour activity of novel, mitochondrial-interactive, gold-based lipophilic cations.

  Metal-based drugs 20080101

• Extensively drug resistant tuberculosis in a high income country: a report of four unrelated cases.

  BMC infectious diseases 20080101

• Corticosteroid pulse therapy for leprosy complicated by a severe type 1 reaction.

  Chang Gung medical journal 20080101

• On the action of cyclosporine A, rapamycin and tacrolimus on M. avium including subspecies paratuberculosis.

  PloS one 20080101

• Sweet's syndrome in a patient with Crohn's disease: a case report.

  Journal of medical case reports 20080101

• On the prevalence of M. avium subspecies paratuberculosis DNA in the blood of healthy individuals and patients with inflammatory bowel disease.

  PloS one 20080101

• Recurrent prurigo nodularis related to infected tonsils: a case report.

  Journal of medical case reports 20080101

• Histopathological study of ocular erythema nodosum leprosum and post-therapeutic scleral perforation: a case report.

  Indian journal of ophthalmology 20080101

• [Hematological, hemostatic and biochemical alterations induced by clofazimine and clarithromycin, in single and multiple doses, in rats].

  Revista da Sociedade Brasileira de Medicina Tropical 20080101

• Tuberculous meningitis presenting with unusual clinical features in Nigerians: Two case reports.

  Cases journal 20080101

• Intraneural injection of corticosteroids to treat nerve damage in leprosy: a case report and review of literature.

  Journal of medical case reports 20080101

• Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes.

  PloS one 20080101

• Necrotic erythema nodosum leprosum with oral mucosal involvement.

  Indian journal of leprosy 20080101

• [Atypical mycobacteriosis of the skin caused by Mycobacterium abscessus in an immunocompetent woman].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20071201

• Pure neural leprosy: steroids prevent neuropathy progression.

  Arquivos de neuro-psiquiatria 20071201

• Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions.

  Current neuropharmacology 20071201

• The Australian antibiotic trial in Crohn's disease: alternative conclusions from the same study.

  Gastroenterology 20071101

• Flawed Australian CD study does not end MAP controversy.

  Gastroenterology 20071101

• Australian Crohn's antibiotic study opens new horizons.

  Gastroenterology 20071101

• Importance of the Australian Crohn's disease antibiotic study.

  Gastroenterology 20071101

• Isotretinoin in acne agminata.

  Saudi medical journal 20071001

• Cheilitis granulomatosa and Melkersson-Rosenthal syndrome: evaluation of gastrointestinal involvement and therapeutic regimens in a series of 14 patients.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20070901

• Photosensitisation induced by clofazimine in a cat.

  Australian veterinary journal 20070901

• [Long-term follow-up of ofloxacin-combined therapy for leprosy patients].

  Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20070901

• Adverse effects from multi-drug therapy in leprosy: a Brazilian study.

  Leprosy review 20070901

• Evolution of vision reducing cataract in skin smear positive lepromatous patients: does it have an inflammatory basis?

  The British journal of ophthalmology 20070801

• A case of feline leprosy caused by Mycobacterium lepraemurium originating from the island of Kythira (Greece): diagnosis and treatment.

  Journal of feline medicine and surgery 20070601

• Two-year combination antibiotic therapy with clarithromycin, rifabutin, and clofazimine for Crohn's disease.

  Gastroenterology 20070601

• Antimycobacterial therapy in Crohn's disease: game over?

  Gastroenterology 20070601

• Anti-mycobacterial therapy in Crohn's disease heals mucosa with longitudinal scars.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20070501

• Drug resistance profile of human Mycobacterium avium complex strains from India.

  Indian journal of medical microbiology 20070401

• Crystal-storing histiocytosis due to massive accumulation of charcot-leyden crystals: a unique association producing colonic polyposis in a 78-year-old woman with eosinophilic colitis.

  The American journal of surgical pathology 20070301

• An unusual rash in an elderly man.

  JAAPA : official journal of the American Academy of Physician Assistants 20070301

• Leprosy in a preschool child--a case report.

  Journal of the Indian Medical Association 20070301

• Long-term cure of disseminated Mycobacterium avium infection in a cat.

  The Veterinary record 20070127

• In silico prediction of pregnane X receptor activators by machine learning approaches.

  Molecular pharmacology 20070101

• Leprosy.

  Clinics in dermatology 20070101

• Pyoderma gangrenosum--a review.

  Orphanet journal of rare diseases 20070101

• Cheilitis granulomatosa associated with Melkersson-Rosenthal syndrome.

  Brazilian journal of otorhinolaryngology 20070101

• Does concomitant hiv infection has any epidemiological, clinical, immunopathological and therapeutic relevance in leprosy?

  Indian journal of leprosy 20070101

• Concomitant age old infections of mankind - tuberculosis and leprosy: a case report.

  Journal of medical case reports 20070101

• Sweet's syndrome--a comprehensive review of an acute febrile neutrophilic dermatosis.

  Orphanet journal of rare diseases 20070101

• A overview of ocular leprosy after 2 decades of multidrug therapy.

  International ophthalmology clinics 20070101

• How can we help patients with refractory chronic graft versus host disease- single centre experience.

  Neoplasma 20070101

• Tissue distribution and deposition of clofazimine in mice following oral administration with or without isoniazid.

  Arzneimittel-Forschung 20070101

• Audiologic monitoring of multi-drug resistant tuberculosis patients on aminoglycoside treatment with long term follow-up.

  BMC ear, nose, and throat disorders 20070101

• Extensively drug-resistant tuberculosis (XDR-TB) - a potential threat in Ireland.

  The open respiratory medicine journal 20070101

• Multidrug therapy regimen for leprosy.

  Journal of the American Academy of Dermatology 20061201

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20061201

• Multidrug therapy in leprosy.

  Journal of the Indian Medical Association 20061201

• Lepromatous leprosy: a review and case report.

  Medicina oral, patologia oral y cirugia bucal 20061101

• Tuberculosis: A re-emerging enemy.

  Journal of molecular and genetic medicine : an international journal of biomedical research 20061101

• [Guideline for the treatment of Hansen's disease in Japan (Second edition)].

  Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20060901

• [Basic evaluation for new antimicrobial susceptibility testing of Mycobacterium leprae by bioluminescence assay (ATP method)].

  Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20060901

• Microspheres from new biodegradable poly(ester amide)s with different ratios of L- and D-alanine for controlled drug delivery.

  Journal of microencapsulation 20060901

• Epidemiology of leprosy and response to treatment in Hong Kong.

  Hong Kong medical journal = Xianggang yi xue za zhi 20060601

• Chronic inflammatory joint disease revealing borderline leprosy.

  Joint, bone, spine : revue du rhumatisme 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Histoid leprosy - unusual presentation.

  International journal of dermatology 20060401

• A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy.

  The American journal of tropical medicine and hygiene 20060301

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20060301

• HIV and lacaziosis, Brazil.

  Emerging infectious diseases 20060301

• Guillain-Barré syndrome-like presentation in borderline leprosy with type-2 reaction.

  Dermatology online journal 20060227

• [Long-term course of necrobiotic xanthogranuloma with ocular involvement].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20060201

• [Cheilitis granulomatosa Melkersson-Rosenthal syndrome].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20060201

• Remitting seronegative symmetrical synovitis with pitting edema in leprosy.

  Clinical rheumatology 20060201

• Disseminated Mycobacterium avium infection in young cats: overrepresentation of Abyssinian cats.

  Journal of feline medicine and surgery 20060201

• First report of leprosy presenting as acute polyarthritis in the setting of type I downgrading lepra reaction.

  Clinical rheumatology 20060201

• Effects of clofazimine on potassium uptake by a Trk-deletion mutant of Mycobacterium tuberculosis.

  The Journal of antimicrobial chemotherapy 20060101

• Onchocerca parasites and Wolbachia endosymbionts: evaluation of a spectrum of antibiotic types for activity against Onchocerca gutturosa in vitro.

  Filaria journal 20060101

• Mycobacterium haemophilum osteomyelitis: case report and review of the literature.

  BMC infectious diseases 20060101

• Tuberculosis chemotherapy: current drug delivery approaches.

  Respiratory research 20060101

• Clofazimine induced enteropathy--a case highlighting the importance of drug induced disease in differential diagnosis.

  Tropical gastroenterology : official journal of the Digestive Diseases Foundation 20060101

• [Dermopathy and peripheral neuropathy].

  Enfermedades infecciosas y microbiologia clinica 20051201

• Diagnosis and treatment of nontuberculous mycobacterial pulmonary diseases: a Korean perspective.

  Journal of Korean medical science 20051201

• The global campaign to eliminate leprosy.

  PLoS medicine 20051201

• Protective role of vitamin E on the oxidative stress in Hansen's disease (Leprosy) patients.

  European journal of clinical nutrition 20051001

• Mycobacterium kansasii: antibiotic susceptibility and PCR-restriction analysis of clinical isolates.

  Journal of medical microbiology 20051001

• Renal hypersensitivity vasculitis associated with dapsone.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20051001

• Double-blind, randomized, controlled clinical trial of clofazimine compared with chloroquine in patients with systemic lupus erythematosus.

  Arthritis and rheumatism 20051001

• Borderline lepromatous leprosy presenting as a single cutaneous plaque.

  The Australasian journal of dermatology 20050801

• Antimicrobial activities of seven novel tetramethylpiperidine-substituted phenazines against multiple-drug-resistant Gram-positive bacteria.

  Chemotherapy 20050801

• Leprosy in a renal transplant recipient: a case report and literature review.

  The Journal of dermatology 20050801

• Linezolid for the treatment of multidrug-resistant tuberculosis.

  The Journal of antimicrobial chemotherapy 20050701

• Partial intestinal obstruction due to clofazimine in a patient with multidrug-resistant tuberculosis.

  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20050601

• Aplastic anaemia associated with multidrug therapy (dapsone, rifampicin and clofazimine) in a patient with lepromatous leprosy.

  Leprosy review 20050601

• [Clofazimine. Current status of therapy with clofazimine (Lampren) for leprosy, erythema leprosum , and other dermatoses after donation of the medicine to the WHO by Novartis].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20050501

• A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR.

  Journal of medicinal chemistry 20050421

• Treatment of relapsing idiopathic nodular panniculitis with clofazimine.

  The British journal of dermatology 20050301

• Multidrug-resistant tuberculosis in Russia: clinical characteristics, analysis of second-line drug resistance and development of standardized therapy.

  European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20050201

• Should isoniazid and clofazimine be used to treat multidrug-resistant tuberculosis?

  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20050201

• Dapsone syndrome with acute renal failure during leprosy treatment: case report.

  The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases 20050201

• Persistent unilateral orbital and eyelid oedema as a manifestation of Melkersson-Rosenthal syndrome.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20050101

• Liposome-encapsulated antibiotics.

  Methods in enzymology 20050101

• Clofazimine as elective treatment for granulomatous cheilitis.

  Journal of drugs in dermatology : JDD 20050101

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20050101

• MDT-MB therapy in paucibacillary leprosy: a clinicopathological assessment.

  Indian journal of dermatology, venereology and leprology 20050101

• Drug-induced corneal complications.

  Current opinion in ophthalmology 20041201

• Comparison of assays for detection of agents causing membrane damage in Staphylococcus aureus.

  The Journal of antimicrobial chemotherapy 20041201

• Reactions and their management.

  Journal of the Indian Medical Association 20041201

• Chemotherapy of leprosy.

  Journal of the Indian Medical Association 20041201

• Present status and future prospects of chemotherapeutics for intractable infections due to Mycobacterium avium complex.

  Current drug discovery technologies 20041201

• DNA damage studies in untreated and treated leprosy patients.

  Mutagenesis 20041101

• Multidrug resistant miliary tuberculosis and Pott's disease in an immunocompetent patient.

  Saudi medical journal 20041001

• Infections due to non-tuberculous mycobacteria (NTM).

  The Indian journal of medical research 20041001

• 10-12 years follow-up of highly bacillated BL/LL leprosy patients on combined chemotherapy and immunotherapy.

  Vaccine 20040909

• Granulomatous glossitis: a case report.

  Journal of oral science 20040901

• Outcome of treatment of multidrug resistant tuberculosis.

  The Ceylon medical journal 20040901

• Gateways to clinical trials.

  Methods and findings in experimental and clinical pharmacology 20040901

• Antimicrobial activity of clofazimine is not dependent on mycobacterial C-type phospholipases.

  The Journal of antimicrobial chemotherapy 20040601

• Shiny red-brown papules in a 21-year-old man. Histoid leprosy.

  Archives of dermatology 20040601

• Intra-abdominal, crystal-storing histiocytosis due to clofazimine in a patient with lepromatous leprosy and concurrent carcinoma of the colon.

  Leprosy review 20040601

• Results of a standardised regimen for multidrug-resistant tuberculosis in Bangladesh.

  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20040501

• Regression of Novikoff rat hepatocellular carcinoma following locoregional administration of a novel formulation of clofazimine in lipiodol.

  Cancer letters 20040415

• Human case of lobomycosis.

  Emerging infectious diseases 20040401

• Tissue concentration, systemic distribution and toxicity of clofazimine--an autopsy study.

  Indian journal of pathology & microbiology 20040401

• Anti-staphylococcal activity and mode of action of clofazimine.

  The Journal of antimicrobial chemotherapy 20040301

• Erythema dyschromicum perstans: response to dapsone therapy.

  International journal of dermatology 20040301

• Relapses in multibacillary patients treated with multi-drug therapy until smear negativity: findings after twenty years.

  International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 20040301

• Parallel assessment of 24 monthly doses of rifampin, ofloxacin, and minocycline versus two years of World Health Organization multi-drug therapy for multi-bacillary leprosy.

  The American journal of tropical medicine and hygiene 20040201

• [Guideline for the treatment of leprosy by new quinolones].

  Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20040201

• A microplate indicator-based method for determining the susceptibility of multidrug-resistant Mycobacterium tuberculosis to antimicrobial agents.

  The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 20040201

• Morbihan's disease: treatment with CO2 laser blepharoplasty.

  The Journal of dermatology 20040201

• New agents active against Mycobacterium avium complex selected by molecular topology: a virtual screening method.

  The Journal of antimicrobial chemotherapy 20040101

• Cheilitis granulomatosa of Melkersson-Rosenthal syndrome: treatment with intralesional corticosteroid injections.

  Allergologia et immunopathologia 20040101

• Optimal management of recalcitrant disorders of hyperpigmentation in dark-skinned patients.

  American journal of clinical dermatology 20040101

• Pharmacokinetics and relative bioavailability of clofazimine in relation to food, orange juice and antacid.

  Tuberculosis (Edinburgh, Scotland) 20040101

• Dapsone hypersensitivity syndrome in an adolescent during treatment during of leprosy.

  Revista do Instituto de Medicina Tropical de Sao Paulo 20040101

• Incidence of neuritis among paucibacillary leprosy patients during treatment and surveillance.

  Indian journal of leprosy 20040101

• Primary multi-drug resistant tuberculosis presented as lymphadenitis in a patient without HIV infection.

  Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20040101

• Chronic recurrent ENL, steroid dependent: long-term treatment with high dose clofazimine.

  Leprosy review 20031201

• Long-term efficacy of 2 year WHO multiple drug therapy (MDT) in multibacillary (MB) leprosy patients.

  International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 20031201

• Ulcerated necrobiosis lipoidica: a combined treatment approach with dermatosurgery and PUVA.

  The international journal of lower extremity wounds 20031201

• Lepromatous leprosy and reversal reaction in a Micronesian immigrant.

  International journal of dermatology 20031101

• Invasive Mycobacterium marinum infections.

  Emerging infectious diseases 20031101

• Treatment of Mycobacterium avium-intracellulare complex lung disease with a macrolide, ethambutol, and clofazimine.

  Chest 20031001

• Along these lines..

  International journal of dermatology 20030901

• Determination of clofazimine in leprosy patients by high-performance liquid chromatography.

  Journal of analytical toxicology 20030901

• Viability and drug susceptibility testing of M. leprae using mouse footpad in 37 relapse cases of leprosy.

  International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 20030901

• [Systemic treatment of cutaneous lupus erythematosus].

  Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20030901

• [A case of Hansen's disease seen in an Indonesian resident, and tracing of the patient after coming back to Indonesia].

  Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20030801

• [A case of lepromatous type Hansen's disease].

  Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20030801

• Emerging aspects of Buruli ulcer.

  Expert review of anti-infective therapy 20030801

• Efficacy of clofazimine-modified cyclodextrin against Mycobacterium avium complex in human macrophages.

  International journal of pharmaceutics 20030709

• Leprosy in a Mexican immigrant.

  The Journal of the Kentucky Medical Association 20030701

• Effects of some antituberculous and anti-leprotic drugs on cathepsins B, H and L.

  Indian journal of clinical biochemistry : IJCB 20030701

• Disseminated Mycobacterium chelonae cutaneous infection: recalcitrant to combined antibiotic therapy.

  The Journal of dermatology 20030601

• Effectiveness of multidrug therapy in multibacillary leprosy: a long-term follow-up of 34 multibacillary leprosy patients treated with multidrug regimens till skin smear negativity.

  Leprosy review 20030601

• Anilinopyrimidines as novel antituberculosis agents.

  Bioorganic & medicinal chemistry letters 20030519

• Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.

  Pharmaceutical research 20030401

• Short report: Treatment failure in Hansen's disease.

  The American journal of tropical medicine and hygiene 20030201

• Less common methods to treat acne.

  Dermatology (Basel, Switzerland) 20030101

• A retrospective study regarding the treatment of lupoid onychodystrophy in 30 dogs and literature review.

  Journal of the American Animal Hospital Association 20030101

• [Leprosy in Brazil].

  Revista da Sociedade Brasileira de Medicina Tropical 20030101

• Dapsone induced cholangitis as a part of dapsone syndrome: a case report.

  BMC gastroenterology 20030101

• Probing cell chemistry with time-of-flight secondary ion mass spectrometry: development and exploitation of instrumentation for studies of frozen-hydrated biological material.

  Rapid communications in mass spectrometry : RCM 20030101

• [Hansen's disease in the laboratory].

  Historia, ciencias, saude--Manguinhos 20030101

• Use of infliximab, an anti-tumor necrosis alpha antibody, for inflammatory dermatoses.

  Journal of cutaneous medicine and surgery 20030101

• [Histoid leprosy with erythema nodosum leprosum].

  Acta leprologica 20030101

• Leprosy.

  Clinical evidence 20021201

• [Sucessful treatment with clofazimine and itraconazole in a 46 year old patient after 32 years duration of disease].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20021001

• [Pyoderma gangrenosum--positive effect of cyclosporin A therapy ].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20021001

• Evaluation of solid dispersions of Clofazimine.

  Drug development and industrial pharmacy 20020901

• Drug susceptibility of Mycobacterium leprae: a retrospective analysis of mouse footpad inoculation results from 1983 to 1997.

  Leprosy review 20020901

• Relapse rates and a 10-year follow-up of a 6-week quadruple drug regimen for multibacillary leprosy.

  Leprosy review 20020901

• Bullous reaction in leprosy: a rare phenomenon.

  International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 20020901

• Hansen's disease mimicking palmoplantar keratoderma.

  International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 20020901

• Biochemical and hematological side effects of clofazimine in leprosy patients.

  Pharmacological research 20020801

• Advances in the diagnosis and treatment of leprosy.

  Expert reviews in molecular medicine 20020722

• Treatment of Hansen's disease.

  American family physician 20020401

• Cheilitis granulomatosa: overview of 13 patients with long-term follow-up--results of management.

  International journal of dermatology 20020401

• Feline leprosy: two different clinical syndromes.

  Journal of feline medicine and surgery 20020301

• Successful treatment of postoperative pyoderma gangrenosum with cyclosporin.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20020301

• Activity of a new class of isonicotinoylhydrazones used alone and in combination with isoniazid, rifampicin, ethambutol, para-aminosalicylic acid and clofazimine against Mycobacterium tuberculosis.

  The Journal of antimicrobial chemotherapy 20020201

• Pyoderma gangrenosum: a report of 21 cases.

  International journal of dermatology 20020201

• [What is your diagnosis? Sensory motor polyneuropathy in borderline leprosy. Trophic skin disorders with ulcerations, local superinfection on the right foot with right inguinal lymphadenopathy].

  Praxis 20020116

• Sweet's syndrome: a review of current treatment options.

  American journal of clinical dermatology 20020101

• Treatment of severe Crohn's disease using antimycobacterial triple therapy--approaching a cure?

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20020101

• Treatment with drugs active against Mycobacterium avium subspecies paratuberculosis can heal Crohn's disease: more evidence for a neglected public health tragedy.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20020101

• Clinical management of pyoderma gangrenosum.

  American journal of clinical dermatology 20020101

• Topical treatment of pyoderma gangraenosum.

  Dermatology (Basel, Switzerland) 20020101

• [A 50-year history of new drugs in Japan: the developments of antileprosy drugs and their epidemiological aspects].

  Yakushigaku zasshi 20020101

• [Systematic search for parasites among leprosy patients in Mali].

  Medecine tropicale : revue du Corps de sante colonial 20020101

• [Adverse effects of multidrug therapy in leprosy patients: a five-year survey at a Health Center of the Federal University of Uberlândia].

  Revista da Sociedade Brasileira de Medicina Tropical 20020101

• Drug resistant-Mycobacterium leprae--results of mouse footpad studies from a laboratory in south India.

  Indian journal of leprosy 20020101

• Pulsed corticosteroid therapy in patients with chronic recurrent ENL: a pilot study.

  Indian journal of leprosy 20020101

• Protagonist. Mycobacterium avium subspecies paratuberculosis is a cause of Crohn's disease.

  Gut 20011201

• Sweet's syndrome in association with generalized granuloma annulare in a patient with previous breast carcinoma.

  Clinical and experimental dermatology 20011101

• Pharmacokinetics of para-aminosalicylic acid granules under four dosing conditions.

  The Annals of pharmacotherapy 20011101

• Nodular rash in an Indonesian girl.

  The Pediatric infectious disease journal 20011101

• Bilateral conjunctival lesions in Melkersson-Rosenthal syndrome.

  The British journal of ophthalmology 20011001

• Cheilitis granulomatosa Miescher: treatment with clofazimine and review of the literature.

  The Annals of otology, rhinology, and laryngology 20011001

• Effects of tetramethylpiperidine (TMP)-substituted phenazines on membrane stability and P-glycoprotein function.

  International journal of oncology 20010901

• Update on leprosy.

  Hospital medicine (London, England : 1998) 20010801

• [Chemotherapy of leprosy: theoretical basis of new guideline in Japan].

  Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20010801

• Pharmacokinetics of cycloserine under fasting conditions and with high-fat meal, orange juice, and antacids.

  Pharmacotherapy 20010801

• Nocardia farcinica pleuritis in a lepromatous patient with severe necrotizing reaction: an unusual presentation.

  International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 20010601

• Newer drugs in leprosy.

  International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 20010601

• Leprosy.

  Indian journal of medical sciences 20010501

• Pyoderma gangrenosum associated with sclerosing cholangitis, type 1 diabetes mellitus and ulcerative colitis.

  Journal of the European Academy of Dermatology and Venereology : JEADV 20010501

• Clofazimine enteropathy in a pediatric bone marrow transplant recipient.

  The Journal of pediatrics 20010401

• [Late reversal leprous reaction appearing 18 months after the termination of treatment].

  Presse medicale (Paris, France : 1983) 20010303

• Cutaneous lupus erythematosus.

  Seminars in cutaneous medicine and surgery 20010301

• [Pyoderma gangrenosum. 15 cases].

  Annales de medecine interne 20010201

• Pyodera gangrenosum after aortic valve replacement.

  The Annals of thoracic surgery 20010101

• Treatment of canine leproid granuloma syndrome: preliminary findings in seven dogs.

  Australian veterinary journal 20010101

• Drugs for discoid lupus erythematosus.

  The Cochrane database of systematic reviews 20010101

• Hansen's disease in a native-born, United States resident, after a brief stay in an endemic area abroad.

  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 20010101

• Assessment of antioxidant activity of some antileprotic drugs.

  Arzneimittel-Forschung 20010101

• Tetramethylpiperidine-substituted phenazines inhibit the proliferation of intrinsically multidrug resistant carcinoma cell lines.

  Investigational new drugs 20010101

• Hepatic and haematological adverse reactions associated with the use of multidrug therapy in leprosy--a five year retrospective study.

  Indian journal of leprosy 20010101

• Leprosy. Recognition and treatment.

  American journal of clinical dermatology 20010101

• Lucio leprosy with lucio phenomenon.

  Indian journal of leprosy 20010101

• [Immuno-allergic accidents with rifamipcin].

  Acta leprologica 20010101

• Use of genomics and combinatorial chemistry in the development of new antimycobacterial drugs.

  Biochemical pharmacology 20000201

• In vitro investigation of the antimicrobial activities of novel tetramethylpiperidine-substituted phenazines against Mycobacterium tuberculosis.

  Chemotherapy 20000101

• Effective treatment of acute and chronic murine tuberculosis with liposome-encapsulated clofazimine.

  Antimicrobial agents and chemotherapy 19990701

• Antimycobacterial activities of riminophenazines.

  The Journal of antimicrobial chemotherapy 19990501

• Activities of eighteen antimicrobial regimens against Mycobacterium avium infection in beige mice.

  Microbial drug resistance (Larchmont, N.Y.) 19990101

• Pulsed-exposure and postantibiotic leukocyte enhancement effects of amikacin, clarithromycin, clofazimine, and rifampin against intracellular Mycobacterium avium.

  Antimicrobial agents and chemotherapy 19981101

• Synergistic activities of antituberculous drugs with cerulenin and trans-cinnamic acid against Mycobacterium tuberculosis.

  FEMS immunology and medical microbiology 19980601

• Antimycobacterial activity of some 2,3-dianilinoquinoxaline derivatives.

  Die Pharmazie 19971001

• Dapsone-induced motor polyneuropathy in a patient with leprosy.

  International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association 19970601

• Microplate alamar blue assay versus BACTEC 460 system for high-throughput screening of compounds against Mycobacterium tuberculosis and Mycobacterium avium.

  Antimicrobial agents and chemotherapy 19970501

• Spectrum of activity of levofloxacin against nontuberculous mycobacteria and its activity against the Mycobacterium avium complex in combination with ethambutol, rifampin, roxithromycin, amikacin, and clofazimine.

  Antimicrobial agents and chemotherapy 19961101

• In vitro activities of fourteen antimicrobial agents against drug susceptible and resistant clinical isolates of Mycobacterium tuberculosis and comparative intracellular activities against the virulent H37Rv strain in human macrophages.

  Current microbiology 19960901

• Comparative activity of azithromycin against clinical isolates of mycobacteria.

  The Journal of antimicrobial chemotherapy 19960901

• Susceptibility testing of Mycobacterium avium complex isolates.

  Antimicrobial agents and chemotherapy 19960801

• Bioluminescence screening in vitro (Bio-Siv) assays for high-volume antimycobacterial drug discovery.

  Antimicrobial agents and chemotherapy 19960601

• Antituberculosis activities of clofazimine and its new analogs B4154 and B4157.

  Antimicrobial agents and chemotherapy 19960301

• Activity of seven antimicrobial agents, alone and in combination, against AIDS-associated isolates of Mycobacterium avium complex.

  The Journal of antimicrobial chemotherapy 19950901

• Determination of MICs for Mycobacterium avium-M. intracellulare complex in liquid medium by a colorimetric method.

  Journal of clinical microbiology 19950701

• [Extra and intracellular activity of dirithromycin against Mycobacterium avium].

  Pathologie-biologie 19950401

• Chemotherapeutic activity of clofazimine and its analogues against Mycobacterium tuberculosis. In vitro, intracellular, and in vivo studies.

  American journal of respiratory and critical care medicine 19950401

• Intracellular activities of roxithromycin used alone and in association with other drugs against Mycobacterium avium complex in human macrophages.

  Antimicrobial agents and chemotherapy 19950401

• Clofazimine: a review of its medical uses and mechanisms of action.

  Journal of the American Academy of Dermatology 19950201

• [New drugs against tuberculosis and nontuberculous mycobacterial infections: a review].

  Kekkaku : [Tuberculosis] 19941101

• Activities of roxithromycin used alone and in combination with ethambutol, rifampin, amikacin, ofloxacin, and clofazimine against Mycobacterium avium complex.

  Antimicrobial agents and chemotherapy 19940601

• Activity of aminosidine (paromomycin) for Mycobacterium tuberculosis and Mycobacterium avium.

  The Journal of antimicrobial chemotherapy 19940201

• In vitro activities of free and liposomal drugs against Mycobacterium avium-M. intracellulare complex and M. tuberculosis.

  Antimicrobial agents and chemotherapy 19931201

• Mycobacterium avium strains resistant to clarithromycin and azithromycin.

  Antimicrobial agents and chemotherapy 19931101

• Anti-Mycobacterium avium activity of quinolones: in vitro activities.

  Antimicrobial agents and chemotherapy 19930901

• Efficacy and safety of multidrug therapy in paucibacillary leprosy in Singapore.

  Leprosy review 19930601

• Evaluation of the activity of a number of antimicrobial agents against mycobacteria within mouse macrophages by a radiometric method.

  The Journal of antimicrobial chemotherapy 19930201

• In-vivo activity of streptomycin and clofazimine against established infections of Mycobacterium avium complex in beige mice.

  The Journal of antimicrobial chemotherapy 19921201

• Spectrum of drugs against atypical mycobacteria: how valid is the current practice of drug susceptibility testing and the choice of drugs?

  Zentralblatt fur Bakteriologie : international journal of medical microbiology 19921201

• Activity of clarithromycin against Mycobacterium avium complex infection in beige mice.

  Antimicrobial agents and chemotherapy 19921101

• TLC G-65 in combination with other agents in the therapy of Mycobacterium avium infection in beige mice.

  The Journal of antimicrobial chemotherapy 19920601

• In vivo activities of newer rifamycin analogs against Mycobacterium avium infection.

  Antimicrobial agents and chemotherapy 19911001

• Comparative in-vitro activity of fleroxacin and other 6-fluoroquinolones against mycobacteria.

  The Journal of antimicrobial chemotherapy 19881001

• In vivo activity of amikacin alone or in combination with clofazimine or rifabutin or both against acute experimental Mycobacterium avium complex infections in beige mice.

  Antimicrobial agents and chemotherapy 19880901

• Clofazimine and other rimino-compounds: minimal inhibitory and minimal bactericidal concentrations at different pHs for Mycobacterium avium complex.

  Tubercle 19880901

• Activity of rifabutin alone or in combination with clofazimine or ethambutol or both against acute and chronic experimental Mycobacterium intracellulare infections.

  The American review of respiratory disease 19870801

• Determination of MICs of conventional and experimental drugs in liquid medium by the radiometric method against Mycobacterium avium complex.

  Drugs under experimental and clinical research 19870101

• Intra-neural ceroid-like pigment following the treatment of lepromatous leprosy with clofazimine (B663; Lamprene).

  Journal of neurology, neurosurgery, and psychiatry 19810201

• Splenic infarction and tissue accumulation of crystals associated with the use of clofazimine (Lamprene; B663) in the treatment of pyoderma gangrenosum.

  The British journal of dermatology 19800201

• [The inhibitory effect of antisera to stable L forms (author's transl)].

  Annales de microbiologie 19730301