20300-02-1 | Thiophene-2-thiocarboxamide

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$33.00	$23.00
5g	97%	in stock	$65.00	$45.00
10g	97%	in stock	$105.00	$74.00
25g	97%	in stock	$248.00	$174.00

Description

• Catalog Number: AB04318
• Chemical Name: Thiophene-2-thiocarboxamide
• CAS Number: 20300-02-1
• Molecular Formula: C5H5NS2
• Molecular Weight: 143.2299
• MDL Number: MFCD00052890
• SMILES: NC(=S)c1cccs1

Computed Properties

• Complexity: 103
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 1.3

Upstream Synthesis Route

Thiophene-2-carbothioamide, also known as thioacetamidothiophene, serves as a versatile building block in chemical synthesis due to its unique properties and reactivity. This compound is commonly utilized in the development of various organic molecules and pharmaceuticals.In chemical synthesis, Thiophene-2-carbothioamide plays a crucial role as a reactive intermediate for the preparation of diverse organic compounds. Its sulfur-containing functional group enables it to participate in a variety of reactions, including nucleophilic substitution, oxidation, and cyclization reactions. By reacting with different reagents and functional groups, this compound can be transformed into a wide range of derivatives with altered chemical structures and properties.One prominent application of Thiophene-2-carbothioamide is its use as a precursor in the synthesis of heterocyclic compounds. Through cyclization reactions, this molecule can be transformed into various functionalized thiophene derivatives, which are important structural motifs found in many biologically active compounds and materials. Additionally, the presence of the carbothioamide group in Thiophene-2-carbothioamide offers opportunities for further functionalization and diversification, allowing for the synthesis of complex organic molecules with tailored properties.Overall, the versatility and reactivity of Thiophene-2-carbothioamide make it a valuable building block in chemical synthesis, offering opportunities for the development of novel compounds with potential applications in pharmaceuticals, materials science, and other fields.

Literature

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101