203787-91-1 | Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, monosodium salt

Packsize	Purity	Availability	Price	Discounted Price
50mg	98%	in stock	$8.00	$5.00
100mg	98%	in stock	$10.00	$7.00
250mg	98%	in stock	$15.00	$10.00
1g	98%	in stock	$25.00	$17.00
5g	98%	in stock	$53.00	$37.00
10g	98%	in stock	$85.00	$59.00
25g	98%	in stock	$142.00	$99.00
100g	98%	in stock	$543.00	$380.00

Description

• Catalog Number: AB50378
• Chemical Name: Octanoic acid, 8-[(2-hydroxybenzoyl)amino]-, monosodium salt
• CAS Number: 203787-91-1
• Molecular Formula: C15H20NNaO4
• Molecular Weight: 301.3134
• MDL Number: MFCD00952954
• SMILES: [O-]C(=O)CCCCCCCNC(=O)c1ccccc1O.[Na+]

Computed Properties

• Complexity: 312
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 9

Literature

• Phase I clinical study to select a novel oral formulation for ibandronate containing the excipient sodium N-[8-(2-hydroxybenzoyl) amino] caprylate (SNAC).

  Die Pharmazie 20120301

• Orally administered glucagon-like peptide-1 affects glucose homeostasis following an oral glucose tolerance test in healthy male subjects.

  Clinical pharmacology and therapeutics 20091201

• Peri- and postnatal developmental toxicity of salcaprozate sodium (SNAC) in Sprague-Dawley rats.

  International journal of toxicology 20090101

• Subchronic oral toxicity of salcaprozate sodium (SNAC) in Sprague-Dawley and Wistar rats.

  International journal of toxicology 20090101

• Mechanistic understanding of oral drug absorption enhancement of cromolyn sodium by an amino acid derivative.

  Pharmaceutical research 20080101

• Modular polyketide synthases and cis double bond formation: establishment of activated cis-3-cyclohexylpropenoic acid as the diketide intermediate in phoslactomycin biosynthesis.

  Journal of the American Chemical Society 20070221

• Promiscuous fatty acyl CoA ligases produce acyl-CoA and acyl-SNAC precursors for polyketide biosynthesis.

  Journal of the American Chemical Society 20050706

• Investigation of the enhancing mechanism of sodium N-[8-(2-hydroxybenzoyl)amino]caprylate effect on the intestinal permeability of polar molecules utilizing a voltage clamp method.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050601

• Oral delivery of insulin with the eligen technology: mechanistic studies.

  Current drug delivery 20050401

• [Effect of casein and protamine on the enzymatic degradation and the orally hypoglycemic action of insulin].

  Yao xue xue bao = Acta pharmaceutica Sinica 20041001

• A novel per-oral insulin formulation: proof of concept study in non-diabetic subjects.

  Diabetic medicine : a journal of the British Diabetic Association 20040401

• Gastrointestinal absorption enhancement of insulin by administration of enteric microspheres and SNAC to rats.

  Journal of microencapsulation 20040201

• [Studies on gastrointestinal absorption enhancement effect and mechanism of sodium N-[8-(2-hydroxybenzyl)amino] caprylate to insulin solution].

  Yao xue xue bao = Acta pharmaceutica Sinica 20031201

• Pathway of oral absorption of heparin with sodium N-[8-(2-hydroxybenzoyl)amino] caprylate.

  Pharmaceutical research 20020801