2081-44-9 | Tetrahydro-2H-pyran-4-ol

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$6.00	$4.00
5g	98%	in stock	$8.00	$5.00
10g	98%	in stock	$8.00	$6.00
25g	98%	in stock	$15.00	$11.00
100g	98%	in stock	$56.00	$39.00
250g	98%	in stock	$139.00	$97.00
500g	98%	in stock	$275.00	$192.00

Description

• Catalog Number: AB18378
• Chemical Name: Tetrahydro-2H-pyran-4-ol
• CAS Number: 2081-44-9
• Molecular Formula: C5H10O2
• Molecular Weight: 102.1317
• MDL Number: MFCD00006633
• SMILES: OC1CCOCC1

Computed Properties

• Complexity: 48
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 7
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: -0.1

Upstream Synthesis Route

With its versatile reactivity and functionality, Tetrahydro-4-Pyranol plays a crucial role in chemical synthesis as a key building block. This compound is widely used in the preparation of a variety of organic compounds, serving as a valuable intermediate in the creation of pharmaceuticals, agrochemicals, and fine chemicals. Its cyclic structure and unique properties enable it to participate in a range of synthetic transformations, including cyclization reactions, ring-opening reactions, and nucleophilic substitutions. Additionally, Tetrahydro-4-Pyranol can be selectively functionalized at different positions, offering chemists a high degree of control over the structural modifications during the synthesis process. Its application in multi-step synthesis pathways highlights its significance in the development of complex molecules with potential applications in various industries such as pharmaceuticals, materials science, and biotechnology.

Literature

• Efficient, highly diastereoselective MS 4 Å-promoted one-pot, three-component synthesis of 2,6-disubstituted-4-tosyloxytetrahydropyrans via Prins cyclization.

  Beilstein journal of organic chemistry 20120101

• Rhenium(VII) catalysis of Prins cyclization reactions.

  Organic letters 20081106