2107-76-8 | 5,7-Dihydroxy-4-methylcoumarin

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$62.00	$44.00
1g	95%	in stock	$66.00	$47.00
5g	95%	in stock	$249.00	$175.00
25g	95%	in stock	$820.00	$574.00

Description

• Catalog Number: AB20243
• Chemical Name: 5,7-Dihydroxy-4-methylcoumarin
• CAS Number: 2107-76-8
• Molecular Formula: C10H8O4
• Molecular Weight: 192.1681
• MDL Number: MFCD00016966
• SMILES: Oc1cc(O)c2c(c1)oc(=O)cc2C
• NSC Number: 5302

Computed Properties

• Complexity: 284
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• XLogP3: 1.1

Literature

• In vitro platelet antiaggregatory properties of 4-methylcoumarins.

  Biochimie 20121201

• Structure-anti-leukemic activity relationship study of ortho-dihydroxycoumarins in U-937 cells: key role of the δ-lactone ring in determining differentiation-inducing potency and selective pro-apoptotic action.

  Bioorganic & medicinal chemistry 20120915

• Biotransformation of hydroxycoumarin derivatives by cultured suspension cells of Catharanthus roseus.

  Die Pharmazie 20120501

• Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents.

  Bioorganic & medicinal chemistry letters 20110201

• Structure-activity relationship of dihydroxy-4-methylcoumarins as powerful antioxidants: correlation between experimental & theoretical data and synergistic effect.

  Biochimie 20100901

• Discovery and optimization of novel 3-piperazinylcoumarin antagonist of chemokine-like factor 1 with oral antiasthma activity in mice.

  Journal of medicinal chemistry 20100225

• Rotational diffusion of dihydroxy coumarins: Effect of OH groups and their relative position on solute-solvent interactions.

  The journal of physical chemistry. B 20090625

• Coumarin as attractive casein kinase 2 (CK2) inhibitor scaffold: an integrate approach to elucidate the putative binding motif and explain structure-activity relationships.

  Journal of medicinal chemistry 20080227

• Antifungal and antibacterial activities of Mexican tarragon (Tagetes lucida).

  Journal of agricultural and food chemistry 20060517

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Inhibitory activity of polyhydroxycarboxylate chelators against recombinant NF-kappaB p50 protein-DNA binding.

  Bioorganic chemistry 20050401

• Crystal structure of 7,8-dihydroxy-4-methylcoumarin.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030401