2127-10-8 | 1,2-Bis(5-nitropyridin-2-yl)disulfane

Packsize	Purity	Availability	Price	Discounted Price
100mg	97%	in stock	$17.00	$12.00
250mg	97%	in stock	$26.00	$19.00
1g	97%	in stock	$51.00	$36.00
5g	97%	in stock	$120.00	$84.00
10g	97%	in stock	$224.00	$157.00
100g	97%	in stock	$1,879.00	$1,316.00

Description

• Catalog Number: AB57057
• Chemical Name: 1,2-Bis(5-nitropyridin-2-yl)disulfane
• CAS Number: 2127-10-8
• Molecular Formula: C10H6N4O4S2
• Molecular Weight: 310.3090399999999
• MDL Number: MFCD00006453
• SMILES: [O-][N+](=O)c1ccc(nc1)SSc1ccc(cn1)[N+](=O)[O-]

Computed Properties

• Complexity: 328
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 20
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• XLogP3: 2.2

Literature

• The use of 2,2'-dithiobis(5-nitropyridine) (DTNP) for deprotection and diselenide formation in protected selenocysteine-containing peptides.

  Journal of peptide science : an official publication of the European Peptide Society 20120301

• 2,2'-Dithiobis(5-nitropyridine) (DTNP) as an effective and gentle deprotectant for common cysteine protecting groups.

  Journal of peptide science : an official publication of the European Peptide Society 20120101

• Redox modulation of A-type K+ currents in pain-sensing dorsal root ganglion neurons.

  Biochemical and biophysical research communications 20080606

• Studies on deprotection of cysteine and selenocysteine side-chain protecting groups.

  Journal of peptide science : an official publication of the European Peptide Society 20070201

• Nitric oxide activates TRP channels by cysteine S-nitrosylation.

  Nature chemical biology 20061101

• Disinactivation of N-type inactivation of voltage-gated K channels by an erbstatin analogue.

  The Journal of biological chemistry 20040709

• Inactivation of the human papillomavirus-16 E6 oncoprotein by organic disulfides.

  Bioorganic & medicinal chemistry 20001101

• Evaluation of selected chemotypes in coupled cellular and molecular target-based screens identifies novel HIV-1 zinc finger inhibitors.

  Journal of medicinal chemistry 19960913