2140-72-9 | 2'-O-Methylcytidine

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$25.00	$18.00
1g	98%	in stock	$30.00	$21.00
5g	98%	in stock	$85.00	$59.00
10g	98%	in stock	$165.00	$115.00
25g	98%	in stock	$410.00	$287.00

Description

• Catalog Number: AI44960
• Chemical Name: 2'-O-Methylcytidine
• CAS Number: 2140-72-9
• Molecular Formula: C10H15N3O5
• Molecular Weight: 257.2432
• MDL Number: MFCD11519076
• SMILES: CO[C@@H]1[C@H](O)[C@H](O[C@H]1n1ccc(nc1=O)N)CO

Computed Properties

• Complexity: 397
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 3
• XLogP3: -1.6

Literature

• Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5'-monophosphates bearing a biodegradable protecting group.

  Organic & biomolecular chemistry 20100507

• The transition from noncoded to coded protein synthesis: did coding mRNAs arise from stability-enhancing binding partners to tRNA?

  Biology direct 20100101

• Transfer RNA modifications and genes for modifying enzymes in Arabidopsis thaliana.

  BMC plant biology 20100101

• Fluorinated methylenecyclopropane analogues of nucleosides. Synthesis and antiviral activity of (Z)- and (E)-9-{[(2-fluoromethyl-2-hydroxymethyl)-cyclopropylidene]methyl}adenine and -guanine.

  Bioorganic & medicinal chemistry 20080301

• Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA.

  Journal of molecular biology 20080125

• Control of gag-pol gene expression in the Candida albicans retrotransposon Tca2.

  BMC molecular biology 20070101

• Inhibitory effect of 2'-substituted nucleosides on hepatitis C virus replication correlates with metabolic properties in replicon cells.

  Antimicrobial agents and chemotherapy 20050501

• Synthesis and evaluation of S-acyl-2-thioethyl esters of modified nucleoside 5'-monophosphates as inhibitors of hepatitis C virus RNA replication.

  Journal of medicinal chemistry 20050224

• Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro.

  The Journal of biological chemistry 20031205

• Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs.

  The Journal of biological chemistry 20030404

• Using capillary electrophoresis to study methylation effect on RNA-peptide interaction.

  Acta biochimica Polonica 20030101

• Synthesis of new 3'-, 5-, and N(4)-modified 2'-O-methylcytidine libraries on solid support.

  Journal of combinatorial chemistry 20030101

• Interaction of RNA with phage display selected peptides analyzed by capillary electrophoresis mobility shift assay.

  RNA (New York, N.Y.) 20020501

• Anticodon domain methylated nucleosides of yeast tRNA(Phe) are significant recognition determinants in the binding of a phage display selected peptide.

  Biochemistry 20011127