21871-47-6 | 5-Benzylthio-1H-tetrazole

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$14.00	$10.00
5g	97%	in stock	$19.00	$13.00
25g	97%	in stock	$76.00	$53.00
100g	97%	in stock	$296.00	$207.00

Description

• Catalog Number: AB68677
• Chemical Name: 5-Benzylthio-1H-tetrazole
• CAS Number: 21871-47-6
• Molecular Formula: C8H8N4S
• Molecular Weight: 192.2409
• MDL Number: MFCD00068731
• SMILES: c1ccc(cc1)CSc1nnn[nH]1
• NSC Number: 282041

Computed Properties

• Complexity: 149
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 13
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 1.8

Upstream Synthesis Route

5-[(Phenylmethyl)thio]-2H-tetrazole is a versatile compound widely utilized in chemical synthesis for its unique properties and reactivity. As a sulfur-containing tetrazole, it serves as a valuable building block in the synthesis of various organic compounds. One of its key applications is in the preparation of pharmaceutical intermediates, where its structural features make it a valuable precursor in drug discovery and development. Additionally, 5-[(Phenylmethyl)thio]-2H-tetrazole is employed in the synthesis of novel materials with potential applications in the fields of materials science and catalysis. Its ability to participate in diverse chemical transformations makes it a valuable tool for organic chemists seeking to introduce functional groups or structural motifs into their target molecules efficiently and selectively.

Literature

• A rapid, cost-effective method of assembly and purification of synthetic DNA probes >100 bp.

  PloS one 20120101

• Synthesis of specifically modified oligonucleotides for application in structural and functional analysis of RNA.

  Journal of nucleic acids 20110101

• DMSO and betaine greatly improve amplification of GC-rich constructs in de novo synthesis.

  PloS one 20100101

• The 4-(N-dichloroacetyl-N-methylamino)benzyloxymethyl group for 2'-hydroxyl protection of ribonucleosides in the solid-phase synthesis of oligoribonucleotides.

  The Journal of organic chemistry 20080404

• RNA synthesis using 2'-O-(tert-butyldimethylsilyl) protection.

  Methods in molecular biology (Clifton, N.J.) 20050101

• Synthesis of selenium-derivatized cytidine and oligonucleotides for X-ray crystallography using MAD.

  Organic letters 20040401