21943-13-5 | 2-Amino-5-bromo-3-chloropyrazine

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$16.00	$11.00
1g	95%	in stock	$22.00	$15.00
10g	95%	in stock	$24.00	$17.00
25g	95%	in stock	$44.00	$31.00
100g	95%	in stock	$167.00	$117.00

Description

• Catalog Number: AD24394
• Chemical Name: 2-Amino-5-bromo-3-chloropyrazine
• CAS Number: 21943-13-5
• Molecular Formula: C4H3BrClN3
• Molecular Weight: 208.44371999999998
• MDL Number: MFCD11109828
• SMILES: Brc1cnc(c(n1)Cl)N

Computed Properties

• Complexity: 102
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.4

Upstream Synthesis Route

2-Pyrazinamine, 5-bromo-3-chloro- is a valuable chemical intermediate used in organic synthesis. This compound plays a crucial role in various chemical reactions, particularly in the pharmaceutical and agrochemical industries. Its unique properties make it an essential building block for the creation of complex molecules.In chemical synthesis, 2-Pyrazinamine, 5-bromo-3-chloro- is utilized as a key starting material for the preparation of biologically active compounds and pharmaceutical drugs. It serves as a versatile precursor in the development of novel molecules with potential therapeutic applications. By incorporating this compound into synthetic pathways, chemists can efficiently access a diverse range of target molecules with enhanced biological activities.Furthermore, the presence of both bromo and chloro functional groups in 2-Pyrazinamine, 5-bromo-3-chloro- offers synthetic chemists the ability to introduce further structural diversity into the target molecules. These functional groups can undergo various chemical transformations, such as substitution reactions, enabling the modification and fine-tuning of the final compound's properties.Overall, the application of 2-Pyrazinamine, 5-bromo-3-chloro- in chemical synthesis is instrumental in the development of new pharmaceuticals, agrochemicals, and materials. Its versatility and reactivity make it a valuable tool for synthetic chemists seeking to create innovative molecules with diverse applications.

Literature

• Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization.

  Journal of medicinal chemistry 20101111