21987-29-1 | 4,4-Difluoropiperidine

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$8.00	$5.00
1g	98%	in stock	$8.00	$6.00
5g	98%	in stock	$21.00	$15.00
10g	98%	in stock	$39.00	$28.00
25g	98%	in stock	$90.00	$63.00
100g	98%	in stock	$356.00	$250.00

Description

• Catalog Number: AF28988
• Chemical Name: 4,4-Difluoropiperidine
• CAS Number: 21987-29-1
• Molecular Formula: C5H9F2N
• Molecular Weight: 121.1285
• MDL Number: MFCD03094281
• SMILES: FC1(F)CCNCC1

Computed Properties

• Complexity: 74.5
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 1
• XLogP3: 1

Upstream Synthesis Route

4,4-Difluoropiperidine is a valuable building block in chemical synthesis, particularly in the pharmaceutical industry. Its unique structure and properties make it a versatile compound for creating a wide range of organic molecules. In the field of medicinal chemistry, 4,4-Difluoropiperidine can be used as a key intermediate in the synthesis of various pharmaceutical agents, including potential drug candidates. With its fluorine substituents and piperidine ring, this compound offers opportunities for introducing specific functional groups and enhancing the biological activity of the final products. Additionally, the stability and reactivity of 4,4-Difluoropiperidine make it a valuable tool for designing novel molecules with desired pharmacological properties. In summary, the application of 4,4-Difluoropiperidine in chemical synthesis plays a crucial role in the development of new pharmaceuticals and other biologically active compounds.

Literature

• SSR182289A, a selective and potent orally active thrombin inhibitor.

  Bioorganic & medicinal chemistry 20040401