22199-08-2 | 4-amino-N-argentio-N-(pyrimidin-2-yl)benzene-1-sulfonamide

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$8.00	$6.00
5g	97%	in stock	$31.00	$22.00
25g	97%	in stock	$108.00	$76.00

Description

• Catalog Number: AI45268
• Chemical Name: 4-amino-N-argentio-N-(pyrimidin-2-yl)benzene-1-sulfonamide
• CAS Number: 22199-08-2
• Molecular Formula: C10H9AgN4O2S
• Molecular Weight: 357.13726
• MDL Number: MFCD00072101
• SMILES: Nc1ccc(cc1)S1(=O)=[O][Ag+][N]2=CC=C[N-]C2=N1

Computed Properties

• Complexity: 327
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3

Literature

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• [Clinical observation of the efficacy of MEBO in the treatment of burn patients with burn area over 50% TBSA].

  Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20060201

• Adjuvant dressing for negative pressure wound therapy in burns.

  Ostomy/wound management 20060101

• Semapimod reduces the depth of injury resulting in enhanced re-epithelialization of partial-thickness burns in swine.

  Journal of burn care & research : official publication of the American Burn Association 20060101

• Aesthetic skin branding: a novel form of body art with adverse clinical sequela.

  Journal of burn care & research : official publication of the American Burn Association 20060101

• Healing at home: Comparing cohorts of children with medium-sized burns treated as outpatients with in-hospital applied Acticoat to those children treated as inpatients with silver sulfadiazine.

  Journal of burn care & research : official publication of the American Burn Association 20060101

• [Effect of silver nanoparticle dressing on second degree burn wound].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20060101

• Work-related burns.

  Clinics in occupational and environmental medicine 20060101

• The effect of topical application of human milk, ethyl alcohol 96%, and silver sulfadiazine on umbilical cord separation time in newborn infants.

  Archives of Iranian medicine 20060101

• Randomized clinical study of Hydrofiber dressing with silver or silver sulfadiazine in the management of partial-thickness burns.

  Journal of burn care & research : official publication of the American Burn Association 20060101

• Accidental burns during surgery.

  Journal of burn care & research : official publication of the American Burn Association 20060101

• Chlorhexidine and silver-sulfadiazine coated central venous catheters in haematological patients--a double-blind, randomised, prospective, controlled trial.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20051201

• Central venous catheter colonization in critically ill patients: a prospective, randomized, controlled study comparing standard with two antiseptic-impregnated catheters.

  Anesthesia and analgesia 20051201

• The use of topical negative pressure in a paediatric patient with extensive burns.

  Burns : journal of the International Society for Burn Injuries 20051201

• [Topical silver sulfadiazine-induced acute renal failure].

  Annales de dermatologie et de venereologie 20051101

• Summaries for patients. Can antibiotic-coated catheters help decrease the incidence of bloodstream infections in patients in the intensive care unit?

  Annals of internal medicine 20051018

• Effect of a second-generation venous catheter impregnated with chlorhexidine and silver sulfadiazine on central catheter-related infections: a randomized, controlled trial.

  Annals of internal medicine 20051018

• Infection and the chronic wound: a focus on silver.

  Advances in skin & wound care 20051001

• Octylcyanoacrylate for the treatment of small, superficial, partial-thickness burns: a pilot study.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20050901

• Reversal of silver sulfadiazine-impaired wound healing by epidermal growth factor.

  Biomaterials 20050801

• A silver coated dressing reduces the incidence of early burn wound cellulitis and associated costs of inpatient treatment: comparative patient care audits.

  Burns : journal of the International Society for Burn Injuries 20050801

• Treatment of second degree facial burns with allografts--preliminary results.

  Burns : journal of the International Society for Burn Injuries 20050801

• Second-degree burns: a comparative, multicenter, randomized trial of hyaluronic acid plus silver sulfadiazine vs. silver sulfadiazine alone.

  Current medical research and opinion 20050801

• Bacterial and fungal colonization of burn wounds.

  Memorias do Instituto Oswaldo Cruz 20050801

• The use of sandpaper as a precision tool for dermabrasion in burn surgery.

  Plastic and reconstructive surgery 20050701

• IPM/DOSS/water microemulsions as reactors for silver sulfadiazine nanocrystal synthesis.

  Journal of pharmaceutical sciences 20050601

• The use of Flammacerium in British Burns Units.

  Burns : journal of the International Society for Burn Injuries 20050501

• Bacterial resistance to silver in wound care.

  The Journal of hospital infection 20050501

• Reduction of catheter-related infections in neutropenic patients: a prospective controlled randomized trial using a chlorhexidine and silver sulfadiazine-impregnated central venous catheter.

  Annals of hematology 20050401

• FTR1335 is a novel synthetic inhibitor of Candida albicans N-myristoyltransferase with fungicidal activity.

  Biological & pharmaceutical bulletin 20050401

• Silver sulphadiazine.

  Nursing times 20050301

• Diagnosis: Urine scalding dermatitis.

  Lab animal 20050201

• Idiopathic necrotizing dermatitis: current management.

  Journal of paediatrics and child health 20050101

• Evaluation of cytotoxicity and antimicrobial activity of Acticoat Burn Dressing for management of microbial contamination in cultured skin substitutes grafted to athymic mice.

  The Journal of burn care & rehabilitation 20050101

• Efficacy of moist exposed burn ointment on burns.

  The Journal of burn care & rehabilitation 20050101

• A prospective, randomized trial of Acticoat versus silver sulfadiazine in the treatment of partial-thickness burns: which method is less painful?

  The Journal of burn care & rehabilitation 20050101

• Comparison of silver-coated dressing (Acticoat), chlorhexidine acetate 0.5% (Bactigrass), and silver sulfadiazine 1% (Silverdin) for topical antibacterial effect in Pseudomonas aeruginosa-contaminated, full-skin thickness burn wounds in rats.

  The Journal of burn care & rehabilitation 20050101

• [Microbiological evaluation of 1% silver sulfadiazine dressings].

  Revista latino-americana de enfermagem 20050101

• [The effect of silver sulfadiazine on Acinetobacter baumannii strains isolated in burn units].

  Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101

• The effect of essential oils on methicillin-resistant Staphylococcus aureus using a dressing model.

  Burns : journal of the International Society for Burn Injuries 20041201

• Susceptibility of coagulase-negative staphylococcal nosocomial bloodstream isolates to the chlorhexidine/silver sulfadiazine-impregnated central venous catheter.

  American journal of infection control 20041201

• Plantar burns in children: epidemiology and sequelae.

  Annals of plastic surgery 20041101

• Oxacillin- and mupirocin-resistant Staphylococcus aureus: in vitro activity of silver sulphadiazine and cerium nitrate in hospital strains.

  Journal of chemotherapy (Florence, Italy) 20041001

• The use of homograft compared to topical antimicrobial therapy in the treatment of second-degree burns of more than 40% total body surface area.

  Burns : journal of the International Society for Burn Injuries 20040901

• Tape blisters that develop after hip fracture surgery: a retrospective series and a review of the literature.

  American journal of orthopedics (Belle Mead, N.J.) 20040901

• Treatment of partial-thickness burns: a prospective, randomized trial using Transcyte.

  ANZ journal of surgery 20040801

• Treatment of minor burns: treatment of burns is controversial.

  BMJ (Clinical research ed.) 20040731

• Is there enough clinical evidence to use honey to manage wounds?

  Journal of wound care 20040701

• Endotracheal tubes coated with antiseptics decrease bacterial colonization of the ventilator circuits, lungs, and endotracheal tube.

  Anesthesiology 20040601

• Prevention of intravascular catheter-related infection with newer chlorhexidine-silver sulfadiazine-coated catheters: a randomized controlled trial.

  Intensive care medicine 20040501

• Grand mal seizure in a child 30 minutes after Cyclogyl (cyclopentolate hydrochloride) and 10% Neo-Synephrine (phenylephrine hydrochloride) eye drops were instilled.

  Pediatrics 20040501

• [The use of subatmospheric pressure to prevent burn wound progression: first experiences in burn wound treatment].

  Zentralblatt fur Chirurgie 20040501

• Catheter-associated infections: pathogenesis affects prevention.

  Archives of internal medicine 20040426

• Evaluation of a triple-lumen central venous heparin-coated catheter versus a catheter coated with chlorhexidine and silver sulfadiazine in critically ill patients.

  Intensive care medicine 20040401

• A randomized controlled trial of silver sulfadiazine, biafine, and saline-soaked gauze in the treatment of superficial partial-thickness burn wounds in pigs.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20040401

• A randomized, controlled trial of tea tree topical preparations versus a standard topical regimen for the clearance of MRSA colonization.

  The Journal of hospital infection 20040401

• Childhood shingles. Herpes zoster can occur in healthy children too.

  Postgraduate medicine 20040401

• How safe is silver in wound care?

  Journal of wound care 20040401

• A silver sulphadiazine-impregnated lipidocolloid wound dressing to treat second-degree burns.

  Journal of wound care 20040401

• Cytotoxicity of topical antimicrobial agents used in burn wounds in Australasia.

  ANZ journal of surgery 20040301

• A review of the use of silver in wound care: facts and fallacies.

  British journal of nursing (Mark Allen Publishing) 20040301

• Comparison of four different dressings on donor site wounds.

  British journal of nursing (Mark Allen Publishing) 20040301

• Plastic surgery.

  Journal of the Royal Army Medical Corps 20040301

• An in vitro study of the anti-microbial efficacy of a 1% silver sulphadiazine and 0.2% chlorhexidine digluconate cream, 1% silver sulphadiazine cream and a silver coated dressing.

  Burns : journal of the International Society for Burn Injuries 20040201

• Diagnosis and treatment of four stallions, carriers of the contagious metritis organism--case report.

  Theriogenology 20040115

• Unilateral aplasia cutis congenita on the leg.

  Pediatric dermatology 20040101

• [Hydro-cellular dressing and silver sulfadiazine. Evaluation of its combination in the treatment of infected skin ulcers].

  Revista de enfermeria (Barcelona, Spain) 20040101

• Topical treatment of partial thickness burns by silver sulfadiazine plus hyaluronic acid compared to silver sulfadiazine alone: a double-blind, clinical study.

  Drugs under experimental and clinical research 20040101

• Retardation of wound healing by silver sulfadiazine is reversed by Aloe vera and nystatin.

  Burns : journal of the International Society for Burn Injuries 20031201

• Scar-localized argyria secondary to silver sulfadiazine cream.

  Journal of the American Academy of Dermatology 20031001

• Effect of topically applied silver sulfadiazine on fibroblast cell proliferation and biomechanical properties of the wound.

  Archives of pharmacal research 20031001

• Comparison of microbial adherence to antiseptic and antibiotic central venous catheters using a novel agar subcutaneous infection model.

  The Journal of antimicrobial chemotherapy 20030901

• Chemical injuries: the Tasmanian burns unit experience.

  ANZ journal of surgery 20030901

• [Lipidocolloid dressing can be changed without wound damage. No adhesion to the wound].

  MMW Fortschritte der Medizin 20030821

• Synergistic effect of bismuth subgallate and borneol, the major components of Sulbogin, on the healing of skin wound.

  Biomaterials 20030801

• New choices for central venous catheters: potential financial implications.

  Chest 20030701

• Evaluation of the antimicrobial efficacy of urinary catheters impregnated with antiseptics in an in vitro urinary tract model.

  Infection control and hospital epidemiology 20030701

• Bacterial silver resistance: molecular biology and uses and misuses of silver compounds.

  FEMS microbiology reviews 20030601

• Colonization of burn wounds in Ain Shams University Burn Unit.

  Burns : journal of the International Society for Burn Injuries 20030501

• Bromoderma.

  International journal of dermatology 20030501

• Effect of central venous catheter type on infections: a prospective clinical trial.

  The Journal of hospital infection 20030501

• The relationship between methodological trial quality and the effects of impregnated central venous catheters.

  Intensive care medicine 20030301

• An interesting case of chemical burn injury of the genital perianal region caused by hydrochloric acid exposure.

  Burns : journal of the International Society for Burn Injuries 20030301

• Major burn injury caused by helium vapour.

  Burns : journal of the International Society for Burn Injuries 20030301

• Antibacterial activity and endotoxin-binding capacity of Actisorb Silver 220.

  The Journal of hospital infection 20030301

• Possible captopril-induced toxic epidermal necrolysis.

  The Annals of pharmacotherapy 20030301

• A reappraisal of the role of cerium in burn wound management.

  Journal of wound care 20030301

• Which antimicrobial impregnated central venous catheter should we use? Modeling the costs and outcomes of antimicrobial catheter use.

  American journal of infection control 20030201

• Modulation of inflammatory and catabolic responses in severely burned children by early burn wound excision in the first 24 hours.

  Archives of surgery (Chicago, Ill. : 1960) 20030201

• The antimicrobial benefits of silver and the relevance of microlattice technology.

  Ostomy/wound management 20030201

• Clinical experience using silver antimicrobial dressings on venous stasis ulcers.

  Ostomy/wound management 20030201

• Effects of topical application of antimicrobials and bandaging on healing and granulation tissue formation in wounds of the distal aspect of the limbs in horses.

  American journal of veterinary research 20030101

• Cost-effectiveness of an antiseptic-impregnated central venous catheter in the ICU.

  Intensive care medicine 20030101

• Comparison of silver sulfadiazine 1%, mupirocin 2%, and fusidic acid 2% for topical antibacterial effect in methicillin-resistant staphylococci-infected, full-skin thickness rat burn wounds.

  The Journal of burn care & rehabilitation 20030101

• Topical antimicrobial agents in dermatology.

  Clinics in dermatology 20030101

• Silver-sulfadiazine eschar pigmentation mimics invasive wound infection: a case report.

  The Journal of burn care & rehabilitation 20030101

• [Antimicrobial effect. Comparison of wound dressings containing silver].

  Krankenpflege Journal 20030101

• [Intensive care for burn patients].

  La Revue du praticien 20021215

• Central line infections.

  Current opinion in critical care 20021001

• The effects of a high-potency topical steroid on cutaneous healing of burns in pigs.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20021001

• Dressings for burn injury in a military conflict--change of practice based on current evidence.

  Journal of the Royal Army Medical Corps 20020901

• An infection-preventing bilayered collagen membrane containing antibiotic-loaded hyaluronan microparticles: physical and biological properties.

  Artificial organs 20020701

• Complete osseous regeneration of a large skull defect in a patient with cutis aplasia: a conservative approach.

  The Journal of craniofacial surgery 20020701

• Laminin modified infection-preventing collagen membrane containing silver sulfadiazine-hyaluronan microparticles.

  Artificial organs 20020601

• Anal canal amputation and necrosis of the anal sphinchter due to electric current injury.

  International journal of clinical practice 20020601

• Confocal laser microscopic observation of glycocalyx production by Staphylococcus aureus in vitro.

  Journal of dermatological science 20020501

• Silver. 2: Toxicity in mammals and how its products aid wound repair.

  Journal of wound care 20020501

• Control of wound infections using a bilayer chitosan wound dressing with sustainable antibiotic delivery.

  Journal of biomedical materials research 20020305

• Is a silver coating a silver lining?

  Chest 20020301

• Silver-coated endotracheal tubes associated with reduced bacterial burden in the lungs of mechanically ventilated dogs.

  Chest 20020301

• Deep partial thickness burn after contact with a Meal Ready-To-Eat heater.

  Military medicine 20020201

• Comparison of propolis skin cream to silver sulfadiazine: a naturopathic alternative to antibiotics in treatment of minor burns.

  Journal of alternative and complementary medicine (New York, N.Y.) 20020201

• [Increased serum and urinary levels of silver during treatment with topical silver sulfadiazine].

  Annales de dermatologie et de venereologie 20020201

• Evaluation of an antimicrobial-impregnated continuous ambulatory peritoneal dialysis catheter for infection control in rats.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20020101

• Antimicrobial-impregnated central venous catheters.

  The Pediatric infectious disease journal 20020101

• Effects of silver sulphadiazine on the production of exoproteins by Staphylococcus aureus.

  Journal of medical microbiology 20020101

• [A case of primary pyoderma-like aspergillosis occurring in a patient with a cervical spinal cord injury].

  Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20020101

• The beneficial toxicity paradox of antimicrobials in leg ulcer healing impaired by a polymicrobial flora: a proof-of-concept study.

  Dermatology (Basel, Switzerland) 20020101

• [Topic silver sulfadiazine bicytopenia: first case].

  Therapie 20020101

• A comparison of topical Phenytoin with Silverex in the treatment of superficial dermal burn wounds.

  The Central African journal of medicine 20020101

• Development of an artificial dermis preparation capable of silver sulfadiazine release.

  Journal of biomedical materials research 20011205

• Efficacy of antiadhesive, antibiotic and antiseptic coatings in preventing catheter-related infections: review.

  Journal of chemotherapy (Florence, Italy) 20011201

• Management of pressure ulcers.

  Oncology (Williston Park, N.Y.) 20011101

• Antimicrobial-coated/bonded and -impregnated intravascular catheters.

  The Annals of pharmacotherapy 20011001

• In vitro and in vivo efficacy of catheters impregnated with antiseptics or antibiotics: evaluation of the risk of bacterial resistance to the antimicrobials in the catheters.

  Infection control and hospital epidemiology 20011001

• Phase II study assessing the effectiveness of Biafine cream as a prophylactic agent for radiation-induced acute skin toxicity to the breast in women undergoing radiotherapy with concomitant CMF chemotherapy.

  International journal of radiation oncology, biology, physics 20010901

• Myth: silver sulfadiazine is the best treatment for minor burns.

  The Western journal of medicine 20010901

• [The preparation of collagen burn pellicle of compound sulfadiazine silver and assessment of its efficacy in an animal experiment on deep partial thickness burn wound].

  Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20010901

• A case of vaginal argyrosis: all that glistens isn't gold.

  BJOG : an international journal of obstetrics and gynaecology 20010801

• Flamazine is not a debriding agent.

  British journal of nursing (Mark Allen Publishing) 20010801

• Exposure to liquid sulfur mustard.

  Annals of emergency medicine 20010601

• Wound healing activity of the aqueous extract of Thespesia populnea fruit.

  Fitoterapia 20010601

• The effects of octylcyanoacrylate on scarring after burns.

  Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20010201

• An open study comparing topical silver sulfadiazine and topical silver sulfadiazine-cerium nitrate in the treatment of moderate and severe burns.

  Burns : journal of the International Society for Burn Injuries 20010201

• New technologies to prevent intravascular catheter-related bloodstream infections.

  Emerging infectious diseases 20010101

• Morphine-Infused silver sulfadiazine (MISS) cream for burn analgesia: a pilot study.

  The Journal of burn care & rehabilitation 20010101

• Antifungal activity of Ag(I) and Zn(II) complexes of aminobenzolamide (5-sulfanilylamido-1,3,4-thiadiazole-2-sulfonamide) derivatives.

  Journal of enzyme inhibition 20000101

• [An experimental study of metacresol burn].

  Zhonghua zheng xing shao shang wai ke za zhi = Zhonghua zheng xing shao shang waikf [i.e. waike] zazhi = Chinese journal of plastic surgery and burns 19990701

• Antimicrobial activity and action of silver.

  Progress in medicinal chemistry 19940101

• Argyria from excessive use of topical silver sulphadiazine.

  Lancet (London, England) 19920711

• Silver sulphadiazine-induced haemolytic anaemia in a glucose-6-phosphate dehydrogenase-deficient burn patient.

  Burns : journal of the International Society for Burn Injuries 19911001

• Patient tolerance study of topical chlorhexidine diphosphanilate: a new topical agent for burns.

  Burns : journal of the International Society for Burn Injuries 19900601

• Wound healing. The effects of topical antimicrobial agents.

  Archives of dermatology 19791101

• Nephrotic syndrome following topically applied sulfadiazine silver therapy.

  Archives of internal medicine 19740801

• Mechanism of silver sulfadiazine action on burn wound infections.

  Antimicrobial agents and chemotherapy 19740601