22252-43-3 | 7-Amino-3-methyl-3-cephem-4-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
5g	97%	in stock	$14.00	$10.00
10g	97%	in stock	$17.00	$12.00
25g	97%	in stock	$24.00	$17.00
100g	97%	in stock	$83.00	$58.00

Description

• Catalog Number: AB70036
• Chemical Name: 7-Amino-3-methyl-3-cephem-4-carboxylic acid
• CAS Number: 22252-43-3
• Molecular Formula: C8H10N2O3S
• Molecular Weight: 214.2416
• MDL Number: MFCD00151456
• SMILES: O=C1[C@@H](N)[C@@H]2N1C(=C(CS2)C)C(=O)O

Computed Properties

• Complexity: 353
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 2
• Heavy Atom Count: 14
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -3.1

Literature

• Anaerobic stabilization and conversion of transformed intermediates of antibiotic pharmaceutical effluent in a fluidized bed reactor.

  Journal of environmental science & engineering 20110701

• Effect of loading rate and HRT on the removal of cephalosporin and their intermediates during the operation of a membrane bioreactor treating pharmaceutical wastewater.

  Environmental technology 20090901

• Enzymatic preparation of cefaclor with immobilized penicillin acylase.

  Preparative biochemistry & biotechnology 20080101

• Penicillin acylase-catalyzed synthesis of beta-lactam antibiotics in highly condensed aqueous systems: beneficial impact of kinetic substrate supersaturation.

  Biotechnology and bioengineering 20040205

• Analysis of a substrate specificity switch residue of cephalosporin acylase.

  Biochemical and biophysical research communications 20031219

• Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of beta-lactam antibiotics.

  European journal of biochemistry 20030901

• Continuous cultivations of a Penicillium chrysogenum strain expressing the expandase gene from Streptomyces clavuligerus: Growth yields and morphological characterization.

  Biotechnology and bioengineering 20030805

• Enhanced enzymatic synthesis of a semi-synthetic cephalosprin, cefaclor, with in situ product removal.

  Biotechnology letters 20030701

• Integrated reactor concepts for the enzymatic kinetic synthesis of cephalexin.

  Biotechnology and bioengineering 20021020

• Quantitative characterization of the nucleophile reactivity in penicillin acylase-catalyzed acyl transfer reactions.

  Biochimica et biophysica acta 20020923

• Advantages of using non-isothermal bioreactors for the enzymatic synthesis of antibiotics: the penicillin G acylase as enzyme model.

  Biotechnology and bioengineering 20020805

• A two-step, one-pot enzymatic synthesis of cephalexin from D-phenylglycine nitrile.

  Biotechnology and bioengineering 20020805

• Enzyme reaction engineering: effect of methanol on the synthesis of antibiotics catalyzed by immobilized penicillin G acylase under isothermal and non-isothermal conditions.

  Biotechnology progress 20020101

• Modeling of the enzymatic kinetic synthesis of cephalexin--influence of substrate concentration and temperature.

  Biotechnology and bioengineering 20010505

• Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase.

  Cellular and molecular life sciences : CMLS 20010501