22259-53-6 | (1H-Indol-3-yl)methanamine

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$79.00	$55.00
5g	98%	in stock	$352.00	$246.00
10g	98%	in stock	$586.00	$410.00
25g	98%	in stock	$1,435.00	$1,005.00

Description

• Catalog Number: AI45286
• Chemical Name: (1H-Indol-3-yl)methanamine
• CAS Number: 22259-53-6
• Molecular Formula: C9H10N2
• Molecular Weight: 146.1891
• MDL Number: MFCD01631210
• SMILES: NCc1c[nH]c2c1cccc2

Computed Properties

• Complexity: 136
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 0.8

Literature

• Discovery of the first irreversible small molecule inhibitors of the interaction between the vitamin D receptor and coactivators.

  Journal of medicinal chemistry 20120524

• Discovery of inhibitors and substrates of brassinin hydrolase: Probing selectivity with dithiocarbamate bioisosteres.

  Bioorganic & medicinal chemistry 20120101

• Dinuclear zinc catalyzed asymmetric Friedel-Crafts amidoalkylation of indoles with aryl aldimines.

  Organic & biomolecular chemistry 20110421

• Synthesis and in vitro antifungal evaluation of 2-(2,4-difluorophenyl)-1-[(1H-indol-3-ylmethyl)methylamino]-3-(1H-1,2,4-triazol-1-yl)propan-2-ols.

  Journal of enzyme inhibition and medicinal chemistry 20110401

• Squaramide-catalyzed enantioselective Friedel-Crafts reaction of indoles with imines.

  Chemical communications (Cambridge, England) 20100507

• Substrate specificity and inhibition of brassinin hydrolases, detoxifying enzymes from the plant pathogens Leptosphaeria maculans and Alternaria brassicicola.

  The FEBS journal 20091201

• N-Methyltransferase involved in gramine biosynthesis in barley: cloning and characterization.

  Phytochemistry 20060901

• Asymmetric Friedel-Crafts addition of indoles to N-sulfonyl aldimines: a simple approach to optically active 3-indolyl-methanamine derivatives.

  Organic letters 20060413

• Binding of beta-carbolines at imidazoline I2 receptors: a structure-affinity investigation.

  Bioorganic & medicinal chemistry letters 20040223

• An MCASE approach to the search of a cure for Parkinson's Disease.

  BMC pharmacology 20020101

• [Antimycobacterial indole derivatives].

  Archiv der Pharmazie 19940201