22276-95-5 | 5-Bromo-4-chloro-7h-pyrrolo[2,3-d]pyrimidine

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$8.00	$5.00
5g	97%	in stock	$10.00	$7.00
10g	97%	in stock	$12.00	$9.00
25g	97%	in stock	$29.00	$21.00
100g	97%	in stock	$104.00	$73.00

Description

• Catalog Number: AB70071
• Chemical Name: 5-Bromo-4-chloro-7h-pyrrolo[2,3-d]pyrimidine
• CAS Number: 22276-95-5
• Molecular Formula: C6H3BrClN3
• Molecular Weight: 232.4651
• MDL Number: MFCD09702029
• SMILES: Brc1c[nH]c2c1c(Cl)ncn2
• NSC Number: 103801

Computed Properties

• Complexity: 157
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• XLogP3: 2.3

Upstream Synthesis Route

5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine, also known as $name$, is a versatile compound widely used in chemical synthesis. Its unique structure and reactivity make it a valuable building block in the creation of various pharmaceuticals, agrochemicals, and materials. In organic synthesis, $name$ serves as a key intermediate in the construction of complex molecules due to its ability to participate in diverse reactions such as cross-coupling, nucleophilic substitution, and heterocyclic ring formation. Its halogen substituents can be selectively modified to introduce specific functional groups, allowing for fine-tuning of the target molecule's properties. Furthermore, the presence of both bromine and chlorine atoms in $name$ provides opportunities for regioselective transformations, enabling precise control over the desired product outcomes. Researchers and chemists leverage the synthetic utility of 5-Bromo-4-chloro-7H-pyrrolo[2,3-d]pyrimidine to streamline the production of novel compounds with potential applications in various fields of science and technology.

Literature

• Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling.

  Nature chemical biology 20160501