22862-76-6 | 3,4-Pyrrolidinediol, 2-[(4-methoxyphenyl)methyl]-, 3-acetate,(2R,3S,4S)-

Packsize	Purity	Availability	Price	Discounted Price
1mg	95%	in stock	$22.00	$15.00
10mg	95%	in stock	$38.00	$26.00
50mg	95%	in stock	$98.00	$68.00
100mg	95%	in stock	$148.00	$103.00
250mg	95%	in stock	$293.00	$205.00
1g	95%	in stock	$1,003.00	$702.00

Description

• Catalog Number: AI66035
• Chemical Name: 3,4-Pyrrolidinediol, 2-[(4-methoxyphenyl)methyl]-, 3-acetate,(2R,3S,4S)-
• CAS Number: 22862-76-6
• Molecular Formula: C14H19NO4
• Molecular Weight: 265.305
• MDL Number: MFCD00077650
• SMILES: COc1ccc(cc1)C[C@H]1NC[C@@H]([C@H]1OC(=O)C)O
• NSC Number: 76712

Computed Properties

• Complexity: 302
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 3
• Heavy Atom Count: 19
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 5
• XLogP3: 0.9

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  Biochimica et biophysica acta 20080201

• Distinct single but not necessarily repeated tetanization is required to induce hippocampal late-LTP in the rat CA1.

  Learning & memory (Cold Spring Harbor, N.Y.) 20080201

• Long-lasting second stage of recognition memory consolidation in mice.

  Behavioural brain research 20080125

• Administration of the protein synthesis inhibitor, anisomycin, has distinct sleep-promoting effects in lateral preoptic and perifornical hypothalamic sites in rats.

  Neuroscience 20080102

• Protein synthesis inhibition before or after stress exposure results in divergent endocrine and BDNF responses disassociated from behavioral responses.

  Depression and anxiety 20080101

• Activation of p38 mitogen-activated protein kinase abolishes insulin-mediated myocardial protection against ischemia-reperfusion injury.

  American journal of physiology. Endocrinology and metabolism 20080101

• p38MAPK delta controls c-Myb degradation in response to stress.

  Blood cells, molecules & diseases 20080101

• Characterization of Ninjurin and TSC22 induction after X-irradiation of normal human skin cells.

  The Journal of dermatology 20080101

• Anisomycin inhibits the behaviors of T cells and the allogeneic skin transplantation in mice.

  Journal of immunotherapy (Hagerstown, Md. : 1997) 20080101

• The activity of caspase-1 is increased in lesional psoriatic epidermis.

  The Journal of investigative dermatology 20071201

• Central mineralocorticoid receptors are indispensable for corticosterone-induced impairment of memory retrieval in rats.

  Neuroscience 20071123

• Effects of protein synthesis inhibitors during reactivation of associative memory in the common snail induces reversible and irreversible amnesia.

  Neuroscience and behavioral physiology 20071101

• Long-acting kappa opioid antagonists disrupt receptor signaling and produce noncompetitive effects by activating c-Jun N-terminal kinase.

  The Journal of biological chemistry 20071012

• Translation of striatal-enriched protein tyrosine phosphatase (STEP) after beta1-adrenergic receptor stimulation.

  Journal of neurochemistry 20071001

• Lipopolysaccharide induces early tolerance to excitotoxicity via nitric oxide and cGMP.

  Stroke 20071001

• Malignant mesothelioma cells are rapidly sensitized to TRAIL-induced apoptosis by low-dose anisomycin via Bim.

  Molecular cancer therapeutics 20071001

• Rapid down-regulation of Ret following exposure of dopaminergic neurons to neurotoxins.

  Journal of neurochemistry 20070901

• A chemical screen identifies anisomycin as an anoikis sensitizer that functions by decreasing FLIP protein synthesis.

  Cancer research 20070901

• Application of Pd(0)-catalyzed intramolecular oxazine formation to the efficient total synthesis of (-)-anisomycin.

  Organic letters 20070830

• Different temporal profiles of amnesia after intra-hippocampus and intra-amygdala infusions of anisomycin.

  Behavioral neuroscience 20070801

• Ribotoxic stress sensitizes glioblastoma cells to death receptor induced apoptosis: requirements for c-Jun NH2-terminal kinase and Bim.

  Molecular cancer research : MCR 20070801

• Dual enzyme-linked immunosorbent assay system for detection of endogenous kinase activities of mitogen- and stress-activated protein kinase-1/2.

  Assay and drug development technologies 20070801

• Stretch and interleukin 1 beta: pro-labour factors with similar mitogen-activated protein kinase effects but differential patterns of transcription factor activation and gene expression.

  Journal of cellular physiology 20070701

• Low-frequency stimulation induces a pathway-specific late phase of LTP in the amygdala that is mediated by PKA and dependent on protein synthesis.

  Learning & memory (Cold Spring Harbor, N.Y.) 20070701

• Temporal requirement of C/EBPbeta in the amygdala following reactivation but not acquisition of inhibitory avoidance.

  Learning & memory (Cold Spring Harbor, N.Y.) 20070701

• Pharmaceutical metabolic down-regulation by protein synthesis inhibition in a conscious rat model.

  Resuscitation 20070601

• Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.

  European journal of pharmacology 20070601

• Synergistic requirements for the induction of dopaminergic D1/D5-receptor-mediated LTP in hippocampal slices of rat CA1 in vitro.

  Neuropharmacology 20070601

• Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.

  Nature chemical biology 20070601

• Anisomycin protects cortical neurons from prolonged hypoxia with differential regulation of p38 and ERK.

  Brain research 20070529

• Post-training, but not post-reactivation, administration of amphetamine and anisomycin modulates Pavlovian conditioned approach.

  Neurobiology of learning and memory 20070501

• Impaired p38 MAPK/HSP27 signaling underlies aging-related failure in opioid-mediated cardioprotection.

  Journal of molecular and cellular cardiology 20070501

• Reversible inactivation of amygdala and cerebellum but not perirhinal cortex impairs reactivated fear memories.

  The European journal of neuroscience 20070501

• Activation of silent synapses with sustained but not decremental long-term potentiation.

  Neuroscience letters 20070424

• Effects of anisomycin on consolidation and reconsolidation of a morphine-conditioned place preference.

  Behavioural brain research 20070312

• Mitogen-activated protein kinases, Erk and p38, phosphorylate and regulate Foxo1.

  Cellular signalling 20070301

• Marked small molecule libraries: a truncated approach to molecular probe design.

  Organic & biomolecular chemistry 20070221

• Anisomycin disrupts a contextual memory following reactivation in a cocaine-induced locomotor activity paradigm.

  Behavioral neuroscience 20070201

• The regulation of ATF3 gene expression by mitogen-activated protein kinases.

  The Biochemical journal 20070115

• Persistent (>24h) long-term depression in the dentate gyrus of freely moving rats is not dependent on activation of NMDA receptors, L-type voltage-gated calcium channels or protein synthesis.

  Neuropharmacology 20070101

• Human Langerhans-cell activation triggered in vitro by conditionally expressed MKK6 is counterregulated by the downstream effector RelB.

  Blood 20070101

• [Role of c-Jun NH (2)-terminal kinase in insulin resistance after burn].

  Zhonghua wai ke za zhi [Chinese journal of surgery] 20070101

• c-Jun N-terminal kinase (JNK) cooperates with Gsk3beta to regulate Dishevelled-mediated microtubule stability.

  BMC cell biology 20070101

• Biotinylated anisomycin: a comparison of classical and 'click' chemistry approaches.

  Bioconjugate chemistry 20070101

• The translation inhibitor anisomycin induces Elk-1-mediated transcriptional activation of egr-1 through multiple mitogen-activated protein kinase pathways.

  Experimental & molecular medicine 20061231

• Ventromedial prefrontal cortex is obligatory for consolidation and reconsolidation of object recognition memory.

  Cerebral cortex (New York, N.Y. : 1991) 20061201

• Involvement of p38 MAP kinase in not only activation of the phagocyte NADPH oxidase induced by formyl-methionyl-leucyl-phenylalanine but also determination of the extent of the activity.

  Journal of biochemistry 20061101

• Mitogen-activated protein kinase signaling is essential for activity-dependent dendritic protein synthesis.

  Neuroreport 20061023

• Intrathecal infusions of anisomycin impact the learning deficit but not the learning effect observed in spinal rats that have received instrumental training.

  Behavioural brain research 20061016

• Intra-hippocampal microinjections of anisomycin did not block glucocorticoid-induced impairment of memory retrieval in rats: an evidence for non-genomic effects of glucocorticoids.

  Behavioural brain research 20061002

• Anisomycin, a protein synthesis inhibitor, disrupts traumatic memory consolidation and attenuates posttraumatic stress response in rats.

  Biological psychiatry 20061001

• NMDA receptors are critical for unleashing consolidated auditory fear memories.

  Nature neuroscience 20061001

• Hippocampal neurons recycle BDNF for activity-dependent secretion and LTP maintenance.

  The EMBO journal 20060920

• The formation of auditory fear memory requires the synthesis of protein and mRNA in the auditory thalamus.

  Neuroscience 20060901

• C-jun N-terminal kinase mediates tumor necrosis factor-alpha suppression of differentiation in myoblasts.

  Endocrinology 20060901

• [Inhibition of protein synthesis during associative memory reactivation produces reversible or irreversible amnesia in the snail Helix lucorum].

  Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20060901

• Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression.

  Neuron 20060817

• p38 mitogen-activated protein kinase mediates the sustained phase of hypoxic pulmonary vasoconstriction and plays a role in phase I vasodilation.

  The Journal of surgical research 20060801

• Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-inflammatory cytokines.

  The Journal of investigative dermatology 20060801

• High-content screening analysis of the p38 pathway: profiling of structurally related p38alpha kinase inhibitors using cell-based assays.

  Assay and drug development technologies 20060801

• Neuronal nitric oxide synthase (nNOS) modulates the JNK1 activity through redox mechanism: a cGMP independent pathway.

  Biochemical and biophysical research communications 20060728

• Protein synthesis inhibition in the basolateral amygdala following retrieval does not impair expression of morphine-associated conditioned place preference.

  Behavioural brain research 20060715

• Regulation of JNK by MKK-7 in fibroblast-like synoviocytes.

  Arthritis and rheumatism 20060701

• Extinction is not a sufficient condition to prevent fear memories from undergoing reconsolidation in the basolateral amygdala.

  The European journal of neuroscience 20060701

• Retrieval induces hippocampal-dependent reconsolidation of spatial memory.

  Learning & memory (Cold Spring Harbor, N.Y.) 20060701

• Stability of recent and remote contextual fear memory.

  Learning & memory (Cold Spring Harbor, N.Y.) 20060701

• A role for hippocampal gastrin-releasing peptide receptors in extinction of aversive memory.

  Neuroreport 20060626

• p38 Mitogen-activated protein kinase mediates IL-8 induction by the ribotoxin deoxynivalenol in human monocytes.

  Toxicology and applied pharmacology 20060615

• Activation of p38 mitogen-activated protein kinase promotes epidermal growth factor receptor internalization.

  Traffic (Copenhagen, Denmark) 20060601

• A novel role for microtubules in apoptotic chromatin dynamics and cellular fragmentation.

  Journal of cell science 20060601

• Sustained activation of c-jun-N-terminal kinase plays a critical role in arsenic trioxide-induced cell apoptosis in multiple myeloma cell lines.

  Cancer science 20060601

• Essential role of somatic and synaptic protein synthesis and axonal transport in long-term synapse-specific facilitation at distal sensorimotor connections in Aplysia.

  The Biological bulletin 20060601

• A concise stereoselective synthesis of Preussin, 3-epi-Preussin, and analogues.

  Organic letters 20060525

• PIASxalpha differentially regulates the amplitudes of transcriptional responses following activation of the ERK and p38 MAPK pathways.

  Molecular cell 20060519

• Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt.

  Oncogene 20060518

• Memory reconsolidation: sensitivity of spatial memory to inhibition of protein synthesis in dorsal hippocampus during encoding and retrieval.

  Neuron 20060504

• Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060503

• Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome.

  Journal of neurophysiology 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Anisomycin activates p38 MAP kinase to induce LTD in mouse primary visual cortex.

  Brain research 20060426

• Microglia provide neuroprotection after ischemia.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060401

• Neuronal activity determines the protein synthesis dependence of long-term potentiation.

  Nature neuroscience 20060401

• Long-term stability of fear memory depends on the synthesis of protein but not mRNA in the amygdala.

  The European journal of neuroscience 20060401

• Persistent disruption of an established morphine conditioned place preference.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20060315

• Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: differential regulation in primary human hepatocytes versus transformed human cells.

  Biochemical and biophysical research communications 20060310

• MAP kinases p38 and JNK are activated by the steroid hormone 1alpha,25(OH)2-vitamin D3 in the C2C12 muscle cell line.

  Journal of cellular biochemistry 20060301

• Protein synthesis and the mechanisms of lasting change in anxiety induced by severe stress.

  Behavioural brain research 20060227

• Inhibition of ERK pathway or protein synthesis during reexposure to drugs of abuse erases previously learned place preference.

  Proceedings of the National Academy of Sciences of the United States of America 20060221

• Shiga toxin 1-induced cytokine production is mediated by MAP kinase pathways and translation initiation factor eIF4E in the macrophage-like THP-1 cell line.

  Journal of leukocyte biology 20060201

• Protein synthesis-dependent reactivation of a contextual conditioned reflex in the common snail.

  Neuroscience and behavioral physiology 20060201

• Protein expression of TNF-alpha in psoriatic skin is regulated at a posttranscriptional level by MAPK-activated protein kinase 2.

  Journal of immunology (Baltimore, Md. : 1950) 20060201

• Inhibition of myocardial apoptosis by ischaemic and beta-adrenergic preconditioning is dependent on p38 MAPK.

  Cardiovascular drugs and therapy 20060201

• Schistosoma mansoni excretory-secretory products stimulate a p38 signalling pathway in Biomphalaria glabrata embryonic cells.

  International journal for parasitology 20060101

• Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease.

  Molecular & cellular proteomics : MCP 20060101

• Anisomycin and the reconsolidation hypothesis.

  Learning & memory (Cold Spring Harbor, N.Y.) 20060101

• Anisomycin infused into the hippocampus fails to block 'reconsolidation' but impairs extinction: the role of re-exposure duration.

  Learning & memory (Cold Spring Harbor, N.Y.) 20060101

• Cytoplasmic domain phosphorylation of heparin-binding EGF-like growth factor.

  Cell structure and function 20060101

• Extinction of conditioned taste aversion depends on functional protein synthesis but not on NMDA receptor activation in the ventromedial prefrontal cortex.

  Learning & memory (Cold Spring Harbor, N.Y.) 20060101

• [Effect of protein synthesis inhibitors on sensitization of defence reaction and on cholinosensitivity of command neurons in Helix lucorum].

  Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova 20060101

• Inhibition of prefrontal protein synthesis following recall does not disrupt memory for trace fear conditioning.

  BMC neuroscience 20060101

• WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53.

  The Journal of biological chemistry 20051230

• Tyrosine phosphorylation of K(ir)3.1 in spinal cord is induced by acute inflammation, chronic neuropathic pain, and behavioral stress.

  The Journal of biological chemistry 20051216

• Ha-Ras sensitizes transformed mouse skin cells to Anisomycin-induced apoptosis.

  FEBS letters 20051121

• Insulin-stimulated glucose uptake does not require p38 mitogen-activated protein kinase in adipose tissue or skeletal muscle.

  Diabetes 20051101

• Apoptosis of bovine ovarian surface epithelial cells by Fas antigen/Fas ligand signaling.

  Reproduction (Cambridge, England) 20051101

• Reconsolidation of a context long-term memory in the terrestrial snail requires protein synthesis.

  Learning & memory (Cold Spring Harbor, N.Y.) 20051101

• AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart.

  Circulation research 20051028

• Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptor-independent synaptic plasticity and spatial memory.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20051026

• Phosphorylation of the retinoid x receptor at the omega loop, modulates the expression of retinoic-acid-target genes with a promoter context specificity.

  Cellular signalling 20051001

• Alpha-rhamnosidase inhibitory activities of polyhydroxylated pyrrolidine.

  Bioorganic & medicinal chemistry letters 20051001

• Local proteins associated with methamphetamine-induced nigrostriatal dopaminergic neurotoxicity.

  Journal of neurochemistry 20051001

• Arsenic trioxide inhibits nuclear receptor function via SEK1/JNK-mediated RXRalpha phosphorylation.

  The Journal of clinical investigation 20051001

• Anisomycin induces COX-2 mRNA expression through p38(MAPK) and CREB independent of small GTPases in intestinal epithelial cells.

  Biochimica et biophysica acta 20050930

• Roles of mTOR and JNK in serine phosphorylation, translocation, and degradation of IRS-1.

  Biochemical and biophysical research communications 20050930

• MSKs are required for the transcription of the nuclear orphan receptors Nur77, Nurr1 and Nor1 downstream of MAPK signalling.

  The Biochemical journal 20050915

• Solid-phase synthesis and anti-infective activity of a combinatorial library based on the natural product anisomycin.

  Bioorganic & medicinal chemistry letters 20050915

• Ribosomal frameshifting on MJD-1 transcripts with long CAG tracts.

  Human molecular genetics 20050915

• Chromosomal protein HMGN1 enhances the acetylation of lysine 14 in histone H3.

  The EMBO journal 20050907

• Cultured embryonic hippocampal neurons deficient in glucocorticoid (GC) receptor: a novel model for studying nongenomic effects of GC in the neural system.

  Endocrinology 20050901

• Lipid efflux in human and mouse macrophagic cells: evidence for differential regulation of phospholipid and cholesterol efflux.

  Journal of lipid research 20050901

• Linking new information to a reactivated memory requires consolidation and not reconsolidation mechanisms.

  PLoS biology 20050901

• Protein synthesis underlies post-retrieval memory consolidation to a restricted degree only when updated information is obtained.

  Learning & memory (Cold Spring Harbor, N.Y.) 20050901

• RACK1 mediates activation of JNK by protein kinase C [corrected].

  Molecular cell 20050805

• Activation of spinal d1/d5 receptors induces late-phase LTP of C-fiber-evoked field potentials in rat spinal dorsal horn.

  Journal of neurophysiology 20050801

• Initiating morphological changes associated with long-term facilitation in Aplysia is independent of transcription or translation in the cell body.

  Journal of neurobiology 20050801

• Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050713

• Downregulation of Ski and SnoN co-repressors by anisomycin.

  FEBS letters 20050704

• Social recognition memory requires two stages of protein synthesis in mice.

  Learning & memory (Cold Spring Harbor, N.Y.) 20050701

• Roles of Rac and p38 kinase in the activation of cytosolic phospholipase A2 in response to PMA.

  The Biochemical journal 20050601

• Ribotoxic stress response to the trichothecene deoxynivalenol in the macrophage involves the SRC family kinase Hck.

  Toxicological sciences : an official journal of the Society of Toxicology 20050601

• PKCdelta and mTOR interact to regulate stress and IGF-I induced IRS-1 Ser312 phosphorylation in breast cancer cells.

  Breast cancer research and treatment 20050601

• Spatial control of protein synthesis.

  Chemistry & biology 20050601

• Light-mediated inhibition of protein synthesis.

  Chemistry & biology 20050601

• Distribution and regulation of L-type calcium channels in deep dorsal horn neurons after sciatic nerve injury in rats.

  The European journal of neuroscience 20050601

• Rapid activation of JNK and p38 by glucocorticoids in primary cultured hippocampal cells.

  Journal of neuroscience research 20050515

• MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2.

  Journal of cell science 20050515

• Complete inhibition of anisomycin and UV radiation but not cytokine induced JNK and p38 activation by an aryl-substituted dihydropyrrolopyrazole quinoline and mixed lineage kinase 7 small interfering RNA.

  The Journal of biological chemistry 20050513

• Stereodivergent syntheses of anisomycin derivatives from D-tyrosine.

  The Journal of organic chemistry 20050513

• Caspase-8 sumoylation is associated with nuclear localization.

  Oncogene 20050505

• Critical roles of Raf/MEK/ERK and PI3K/AKT signaling and inactivation of p38 MAP kinase in the differentiation and survival of monocyte-derived immature dendritic cells.

  Experimental hematology 20050501

• Noradrenaline involvement in the memory-enhancing effects of exposure to a complex rhythm stimulus following discriminated passive avoidance training in the young chick.

  Behavioural brain research 20050415

• c-Jun NH2-terminal kinase-interacting protein-3 facilitates phosphorylation and controls localization of amyloid-beta precursor protein.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413

• Activation of p38 MAP kinase enhances sensitivity of muscle glucose transport to insulin.

  American journal of physiology. Endocrinology and metabolism 20050401

• Cell cycle profiles of EcR, USP, HR3 and B cyclin mRNAs associated to 20E-induced G2 arrest of Plodia interpunctella imaginal wing cells.

  Insect molecular biology 20050401

• Regulation of corticotropin-releasing factor receptor type 2beta mRNA by mitogen-activated protein kinases in aortic smooth muscle cells.

  Regulatory peptides 20050330

• Beta-adrenergic receptor activation facilitates induction of a protein synthesis-dependent late phase of long-term potentiation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050330

• HDM2 phosphorylation by MAPKAP kinase 2.

  Oncogene 20050317

• Developmental switch in synaptic mechanisms of hippocampal metabotropic glutamate receptor-dependent long-term depression.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050316

• Gene regulation of ENaC subunits by serum- and glucocorticoid-inducible kinase-1.

  American journal of physiology. Renal physiology 20050301

• Influence of mRNA and protein synthesis inhibitors on the long-term memory acquisition of classically conditioned earthworms.

  Neurobiology of learning and memory 20050301

• Reinforcement of rat hippocampal LTP by holeboard training.

  Learning & memory (Cold Spring Harbor, N.Y.) 20050301

• A single time-window for protein synthesis-dependent long-term memory formation after one-trial appetitive conditioning.

  The European journal of neuroscience 20050301

• Novel signaling stimulated by arsenite increases cholesterol metabolism through increases in unphosphorylated steroidogenic acute regulatory (StAR) protein.

  Molecular and cellular endocrinology 20050227

• Memory reconsolidation engages only a subset of immediate-early genes induced during consolidation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050223

• Persistent phosphorylation by protein kinase Mzeta maintains late-phase long-term potentiation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050223

• Acquisition, consolidation, reconsolidation, and extinction of eyelid conditioning responses require de novo protein synthesis.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050223

• Activity-dependent long-term potentiation of intrinsic excitability in hippocampal CA1 pyramidal neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050216

• Endocytosis-dependent desensitization and protein synthesis-dependent resensitization in retinal growth cone adaptation.

  Nature neuroscience 20050201

• The effect of intrahippocampal injection of testosterone enanthate (an androgen receptor agonist) and anisomycin (protein synthesis inhibitor) on spatial learning and memory in adult, male rats.

  Behavioural brain research 20050130

• Consolidation and reconsolidation of incentive learning in the amygdala.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20050126

• FGF2-mediated upregulation of urokinase-type plasminogen activator expression requires a MAP-kinase dependent activation of poly(ADP-ribose) polymerase.

  Journal of cellular physiology 20050101

• Autoantibodies specific for apoptotic U1-70K are superior serological markers for mixed connective tissue disease.

  Arthritis research & therapy 20050101

• [Effect of anisomycin on activation of early response genes c-fos, c-jun, Egr-1 in cells transformed by E1A and cHa-ras oncogenes].

  Molekuliarnaia biologiia 20050101

• Investigations of the protein synthesis dependency of mGluR-induced long-term depression in the dentate gyrus of freely moving rats.

  Neuropharmacology 20050101

• Group II mGluR-induced long term depression in the dentate gyrus in vivo is NMDA receptor-independent and does not require protein synthesis.

  Neuropharmacology 20050101

• Onset of amnesia is delayed with a decrease in inhibition of protein synthesis during odor-taste associative learning in the terrestrial slug Limax valentianus.

  Zoological science 20041201

• Memory-like alterations in Aplysia axons after nerve injury or localized depolarization.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20041117

• Memory consolidation and reconsolidation in the rat pup require protein synthesis.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20041117

• Long-term memory for instrumental responses does not undergo protein synthesis-dependent reconsolidation upon retrieval.

  Learning & memory (Cold Spring Harbor, N.Y.) 20041101

• Characterization of fear memory reconsolidation.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20041020

• Cleavage of proBDNF by tPA/plasmin is essential for long-term hippocampal plasticity.

  Science (New York, N.Y.) 20041015

• Hypoxia-responsive growth factors upregulate periostin and osteopontin expression via distinct signaling pathways in rat pulmonary arterial smooth muscle cells.

  Journal of applied physiology (Bethesda, Md. : 1985) 20041001

• Reduced IP receptors in STZ-induced diabetic rat kidneys and high-glucose-treated mesangial cells.

  American journal of physiology. Renal physiology 20041001

• Superinduction of CYP1A1 in MCF10A cultures by cycloheximide, anisomycin, and puromycin: a process independent of effects on protein translation and unrelated to suppression of aryl hydrocarbon receptor proteolysis by the proteasome.

  Molecular pharmacology 20041001

• Context memories and reactivation: constraints on the reconsolidation hypothesis.

  Behavioral neuroscience 20041001

• The type IV-specific phosphodiesterase inhibitor rolipram and its effect on hippocampal long-term potentiation and synaptic tagging.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040901

• Retrieval does not induce reconsolidation of inhibitory avoidance memory.

  Learning & memory (Cold Spring Harbor, N.Y.) 20040901

• Effects of post-session injections of anisomycin on the extinction of a spatial preference and on the acquisition of a spatial reversal preference.

  Behavioural brain research 20040831

• Chromosomal protein HMGN1 modulates histone H3 phosphorylation.

  Molecular cell 20040827

• Osteopontin increases CD44 expression and cell adhesion in RAW 264.7 murine leukemia cells.

  Immunology letters 20040815

• Signalling pathways involved in multisite phosphorylation of the transcription factor ATF-2.

  FEBS letters 20040813

• Inhibition of MKP-1 expression potentiates JNK related apoptosis in renal cancer cells.

  The Journal of urology 20040801

• Latent inhibition of cued fear conditioning: an NMDA receptor-dependent process that can be established in the presence of anisomycin.

  The European journal of neuroscience 20040801

• Phosphorylation of Ser19 increases both Ser40 phosphorylation and enzyme activity of tyrosine hydroxylase in intact cells.

  Journal of neurochemistry 20040801

• Motor skill learning depends on protein synthesis in motor cortex after training.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040721

• Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease.

  The Journal of biological chemistry 20040716

• JNK signaling involved in the effects of cyclic AMP on IL-1beta plus IFNgamma-induced inducible nitric oxide synthase expression in hepatocytes.

  Cellular signalling 20040701

• Mitochondrial signals initiate the activation of c-Jun N-terminal kinase (JNK) by hypoxia-reoxygenation.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701

• Stabilization of thalamo-cortical long-term potentiation by the amygdala: cholinergic and transcription-dependent mechanisms.

  The European journal of neuroscience 20040701

• Consolidation of fear extinction requires protein synthesis in the medial prefrontal cortex.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040623

• Non-genomic regulation of transmitter release by retinoic acid at developing motoneurons in Xenopus cell culture.

  Journal of cell science 20040615

• Evidence of a time-dependent long-term stage of memory for a spatial learning task in the chick (Callus gallus).

  Behavioral neuroscience 20040601

• Reminder effects: the molecular cascade following a reminder in young chicks does not recapitulate that following training on a passive avoidance task.

  The European journal of neuroscience 20040601

• Inhibition of neurotransmitter release by a nonphysiological target requires protein synthesis and involves cAMP-dependent and mitogen-activated protein kinases.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040526

• Facilitation of stress-induced phosphorylation of beta-amyloid precursor protein family members by X11-like/Mint2 protein.

  The Journal of biological chemistry 20040514

• Role of heat shock protein 27 in cytoskeletal remodeling of the airway smooth muscle cell.

  Journal of applied physiology (Bethesda, Md. : 1985) 20040501

• A new antimalarial quassinoid from Simaba orinocensis.

  Journal of natural products 20040501

• Ribosomal protein L3: influence on ribosome structure and function.

  RNA biology 20040501

• Anisomycin downregulates gap-junctional intercellular communication via the p38 MAP-kinase pathway.

  Journal of cell science 20040415

• Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation.

  Biochemical and biophysical research communications 20040402

• MAPK signaling pathways modulate IL-1beta expression in human keratinocytes.

  Archives of biochemistry and biophysics 20040401

• Interleukin (IL)-17 enhances tumor necrosis factor-alpha-stimulated IL-6 synthesis via p38 mitogen-activated protein kinase in osteoblasts.

  Journal of cellular biochemistry 20040401

• A lipid transfer protein gene BG-14 is differentially regulated by abiotic stress, ABA, anisomycin, and sphingosine in bromegrass (Bromus inermis).

  Journal of plant physiology 20040401

• Suppressor of cytokine signaling 6 associates with KIT and regulates KIT receptor signaling.

  The Journal of biological chemistry 20040326

• Platelet factor 4 (PF-4)-induced neutrophil adhesion is controlled by src-kinases, whereas PF-4-mediated exocytosis requires the additional activation of p38 MAP kinase and phosphatidylinositol 3-kinase.

  Blood 20040301

• Reciprocal regulation of beta-adrenergic receptor mRNA stability by mitogen activated protein kinase activation and inhibition.

  Molecular and cellular biochemistry 20040301

• Distinct roles of hippocampal de novo protein synthesis and actin rearrangement in extinction of contextual fear.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20040225

• Delayed preconditioning of the human myocardium: signal transduction and clinical implications.

  Cardiovascular research 20040215

• Early nuclear exclusion of the transcription factor max is associated with retinal ganglion cell death independent of caspase activity.

  Journal of cellular physiology 20040201

• Transcriptional regulation of TNF family receptors and Bcl-2 family by chemotherapeutic agents in murine CT26 cells.

  Journal of cellular biochemistry 20040201

• The amygdala modulates hippocampus-dependent context memory formation and stores cue-shock associations.

  Behavioral neuroscience 20040201

• Differential activation of MAPK signaling pathways by TGF-beta1 forms the molecular mechanism behind its dose-dependent bidirectional effects on hematopoiesis.

  Stem cells and development 20040201

• Anisomycin superinduces annexin V mRNA expression through the ERK1/2 but not the p38 MAP kinase pathway.

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  The European journal of neuroscience 20031201

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