22929-52-8 | 3-Oxotetrahydrofuran

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$6.00	$4.00
1g	97%	in stock	$8.00	$5.00
5g	97%	in stock	$12.00	$8.00
10g	97%	in stock	$18.00	$12.00
25g	97%	in stock	$29.00	$20.00
100g	97%	in stock	$109.00	$76.00

Description

• Catalog Number: AB21015
• Chemical Name: 3-Oxotetrahydrofuran
• CAS Number: 22929-52-8
• Molecular Formula: C4H6O2
• Molecular Weight: 86.0892
• MDL Number: MFCD07778393
• SMILES: O=C1COCC1

Computed Properties

• Complexity: 67.9
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• XLogP3: -0.4

Upstream Synthesis Route

Dihydrofuran-3(2H)-One, also known as gamma-butyrolactone, is a versatile compound commonly used in chemical synthesis. Its unique structure makes it a valuable building block in organic chemistry, where it serves various essential roles.In chemical synthesis, Dihydrofuran-3(2H)-One is commonly employed as a starting material for the production of a wide range of compounds. Its cyclic structure and functional groups make it particularly useful for forming complex molecules through different reaction pathways. One key application of Dihydrofuran-3(2H)-One is in the synthesis of pharmaceuticals, where it can be used as a precursor for active drug ingredients.Additionally, Dihydrofuran-3(2H)-One plays a crucial role in the preparation of fine chemicals, agrochemicals, and other specialty compounds. Its reactivity and versatility allow chemists to functionalize it in various ways, enabling the creation of novel molecules with tailored properties. Overall, the use of Dihydrofuran-3(2H)-One in chemical synthesis demonstrates its significance as a key intermediate in modern organic chemistry.

Literature

• Stereoselective synthesis of donor-acceptor substituted cyclopropafuranones by intramolecular cyclopropanation of vinylogous carbonates: divergent synthesis of tetrahydrofuran-3-one, tetrahydropyran-3-one, and lactones.

  Organic letters 20091203

• Caryophyllenes from a fungal culture of Chrysosporium pilosum.

  Journal of natural products 20090327

• Singlet-oxygen-mediated one-pot synthesis of 3-keto-tetrahydrofurans from 2-(beta-hydroxyalkyl) furans.

  Organic letters 20090115

• Antiplasmodial hirsutinolides from Vernonia staehelinoides and their utilization towards a simplified pharmacophore.

  Phytochemistry 20070401

• Structure-activity studies of cyclic ketone inhibitors of the serine protease plasmin: design, synthesis, and biological activity.

  Bioorganic & medicinal chemistry 20061215

• Modeling deoxyribose radicals by neutralization-reionization mass spectrometry. Part 2. Preparation, dissociations, and energetics of 3-hydroxyoxolan-3-yl radical and cation.

  Journal of the American Society for Mass Spectrometry 20040701

• Enantioselective total syntheses of slagenins A-C and their antipodes.

  The Journal of organic chemistry 20030321