23142-01-0 | Pentoxyverine citrate

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$19.00	$13.00
5g	95%	in stock	$44.00	$31.00
25g	95%	in stock	$122.00	$85.00
100g	95%	in stock	$381.00	$267.00

Description

• Catalog Number: AB22055
• Chemical Name: Pentoxyverine citrate
• CAS Number: 23142-01-0
• Molecular Formula: C26H39NO10
• Molecular Weight: 525.5886
• MDL Number: MFCD00055697
• SMILES: OC(=O)C(CC(=O)O)(CC(=O)O)O.CCN(CCOCCOC(=O)C1(CCCC1)c1ccccc1)CC
• NSC Number: 757833

Computed Properties

• Complexity: 583
• Covalently-Bonded Unit Count: 2
• Heavy Atom Count: 37
• Hydrogen Bond Acceptor Count: 11
• Hydrogen Bond Donor Count: 4
• Rotatable Bond Count: 16

Literature

• Examining protection from anoxic depolarization by the drugs dibucaine and carbetapentane using whole cell recording from CA1 neurons.

  Journal of neurophysiology 20120401

• Characterization of pentoxyverine metabolites in urine using GC/MS after intoxication with Silomat cough drops.

  Forensic science international 20120210

• Cutaneous analgesia and systemic toxicity of carbetapentane and caramiphen in rats.

  Regional anesthesia and pain medicine 20120101

• Simultaneous determination of potassium guaiacolsulfonate, guaifenesin, diphenhydramine HCl and carbetapentane citrate in syrups by using HPLC-DAD coupled with partial least squares multivariate calibration.

  Talanta 20110215

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• A sensitive liquid chromatography-electrospray ionization-mass spectrometry method for the simultaneous determination of pentoxyverine citrate and guaifenesin in human plasma---application to pharmacokinetic and bioequivalence studies.

  Biomedical chromatography : BMC 20100401

• [Quantification of pentoxyverine citrate in human plasma by LC-ESI/MS method and its application].

  Yao xue xue bao = Acta pharmaceutica Sinica 20091201

• Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

  Nature chemical biology 20091001

• Intrathecal administration of sigma-1 receptor agonists facilitates nociception: involvement of a protein kinase C-dependent pathway.

  Journal of neuroscience research 20081201

• Effects of common antitussive drugs on the hERG potassium channel current.

  Journal of cardiovascular pharmacology 20081201

• sigma-1 receptor modulation of acid-sensing ion channel a (ASIC1a) and ASIC1a-induced Ca2+ influx in rat cortical neurons.

  The Journal of pharmacology and experimental therapeutics 20081101

• Activation of the spinal sigma-1 receptor enhances NMDA-induced pain via PKC- and PKA-dependent phosphorylation of the NR1 subunit in mice.

  British journal of pharmacology 20080701

• Sigma-1 receptor activation prevents intracellular calcium dysregulation in cortical neurons during in vitro ischemia.

  The Journal of pharmacology and experimental therapeutics 20061201

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Synthesis and in vitro evaluation of iodinated derivatives of piperazine as a new ligand for sigma receptor imaging by single photon emission computed tomography.

  Chemical & pharmaceutical bulletin 20060401

• Study on the enhancement of Ru(bpy)3(2+) electrochemiluminescence by nanogold and its application for pentoxyverine detection.

  Electrophoresis 20051201

• Retinal bipolar cell input mechanisms in giant danio. I. Electroretinographic analysis.

  Journal of neurophysiology 20050101

• Antagonism of NMDA receptors by sigma receptor ligands attenuates chemical ischemia-induced neuronal death in vitro.

  European journal of pharmacology 20021129

• Spreading depression: imaging and blockade in the rat neocortical brain slice.

  Journal of neurophysiology 20021101

• A non-potentiometric sensing method for the determination of pentoxyverine with PQC sensors based on ion-pair complexes.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20011201

• Carbetapentane attenuates kainate-induced seizures via sigma-1 receptor modulation.

  Life sciences 20010713

• Propiverine-induced Parkinsonism: a case report and a pharmacokinetic/pharmacodynamic study in mice.

  Pharmaceutical research 20000501