23899-73-2 | 4,5-Diaminopyrimidin-2(1H)-one

Packsize	Purity	Availability	Price	Discounted Price
50mg	95%	1 week	$313.00	$219.00
100mg	95%	1 week	$426.00	$299.00
250mg	95%	2 weeks	$543.00	$380.00
500mg	95%	2 weeks	$728.00	$510.00
1g	95%	2 weeks	$874.00	$612.00
5g	95%	2 weeks	$3,254.00	$2,278.00
10g	95%	2 weeks	$4,498.00	$3,149.00

Description

• Catalog Number: AF51633
• Chemical Name: 4,5-Diaminopyrimidin-2(1H)-one
• CAS Number: 23899-73-2
• Molecular Formula: C4H6N4O
• Molecular Weight: 126.1166
• MDL Number: MFCD19203456
• SMILES: Nc1nc(=O)[nH]cc1N

Computed Properties

• Complexity: 205
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 3
• XLogP3: -1.7

Literature

• Compound instability in dimethyl sulphoxide, case studies with 5-aminopyrimidines and the implications for compound storage and screening.

  Bioorganic & medicinal chemistry letters 20121015

• Role of increased guanosine triphosphate cyclohydrolase-1 expression and tetrahydrobiopterin levels upon T cell activation.

  The Journal of biological chemistry 20110422

• Two new polymorphs of 2,6-diaminopyrimidin-4(3H)-one monohydrate.

  Acta crystallographica. Section C, Crystal structure communications 20110101

• Insulin enhances nitric oxide production in trabecular meshwork cells via de novo pathway for tetrahydrobiopterin synthesis.

  Korean journal of ophthalmology : KJO 20070301

• Stable, specific, and reversible base pairing via Schiff base.

  Journal of the American Chemical Society 20051130

• Schiff base-mediated base pairing.

  Nucleic acids symposium series (2004) 20050101

• Phenylalanine improves dilation and blood pressure in GTP cyclohydrolase inhibition-induced hypertensive rats.

  Journal of cardiovascular pharmacology 20040601

• Overexpression of V-1 prevents nitric oxide-induced cell death: involvement of enhanced tetrahydrobiopterin biosynthesis.

  Journal of neuroscience research 20030615

• Regulation of the nitric oxide production resulting from the glucocorticoid-insensitive expression of iNOS in human osteoarthritic cartilage.

  Osteoarthritis and cartilage 20011001