24242-19-1 | 5-Aminonicotinic acid

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$14.00	$10.00
5g	98%	in stock	$19.00	$13.00
25g	98%	in stock	$21.00	$15.00

Description

• Catalog Number: AB68800
• Chemical Name: 5-Aminonicotinic acid
• CAS Number: 24242-19-1
• Molecular Formula: C6H6N2O2
• Molecular Weight: 138.12404
• MDL Number: MFCD00129116
• SMILES: Nc1cc(cnc1)C(=O)O
• NSC Number: 605539

Computed Properties

• Complexity: 138
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -0.3

Upstream Synthesis Route

5-Aminonicotinic acid, also known as 5-AN, is a versatile compound widely utilized in chemical synthesis for various applications. In organic chemistry, 5-AN serves as a key building block for the synthesis of heterocyclic compounds, particularly in the preparation of pharmaceuticals and agrochemicals. Its unique structure and reactivity make it an essential component in the development of novel drugs and bioactive molecules.One of the primary uses of 5-Aminonicotinic acid is as a precursor in the synthesis of pyridine derivatives. By incorporating 5-AN into complex molecules, chemists can modify the properties of the resulting compounds, enhancing their biological activity or altering their chemical reactivity. This ability to fine-tune the structure of organic molecules using 5-Aminonicotinic acid makes it a valuable tool in medicinal chemistry and drug discovery.Additionally, 5-AN can be employed in the production of ligands for metal-catalyzed reactions. Its nitrogen-containing functional group allows for coordination with transition metals, enabling the creation of catalysts with specific stereochemical properties and reactivity profiles. These metal complexes find applications in various organic transformations, such as cross-coupling reactions, hydrogenation, and C-H activation, expanding the synthetic possibilities in organic chemistry.Overall, the versatile nature of 5-Aminonicotinic acid makes it an indispensable reagent in chemical synthesis, providing chemists with a powerful tool to access complex molecules and facilitate the development of new chemical entities with potential therapeutic or industrial applications.

Literature

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501