2441-41-0 | PalGly

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$34.00	$24.00
1g	97%	in stock	$58.00	$40.00
5g	97%	in stock	$216.00	$151.00
25g	97%	in stock	$782.00	$547.00

Description

• Catalog Number: AF31541
• Chemical Name: PalGly
• CAS Number: 2441-41-0
• Molecular Formula: C18H35NO3
• Molecular Weight: 313.4754
• MDL Number: MFCD00153471
• SMILES: CCCCCCCCCCCCCCCC(=O)NCC(=O)O

Computed Properties

• Complexity: 280
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 22
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 16
• XLogP3: 6.5

Literature

• Lipophilic amines as potent inhibitors of N-acylethanolamine-hydrolyzing acid amidase.

  Bioorganic & medicinal chemistry 20120601

• Two new lipoaminoacids with complementary modes of action: new prospects to fight out against skin aging.

  International journal of cosmetic science 20100201

• N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor.

  BMC neuroscience 20100101

• Orphan endogenous lipids and orphan GPCRs: a good match.

  Prostaglandins & other lipid mediators 20090901

• Novel endogenous N-acyl glycines identification and characterization.

  Vitamins and hormones 20090101

• Acylamido analogs of endocannabinoids selectively inhibit cancer cell proliferation.

  Bioorganic & medicinal chemistry 20081115

• A single mutation in P450BM-3 enhances acyl homoserine lactone: acyl homoserine substrate binding selectivity nearly 250-fold.

  Journal of biotechnology 20080731

• N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons.

  Molecular pharmacology 20080701

• Natural variation of potato allene oxide synthase 2 causes differential levels of jasmonates and pathogen resistance in Arabidopsis.

  Planta 20080701

• Interactions of substrates at the surface of P450s can greatly enhance substrate potency.

  Biochemistry 20071211

• Conformational dynamics of the cytochrome P450 BM3/N-palmitoylglycine complex: the proposed 'proximal-distal' transition probed by temperature-jump spectroscopy.

  The journal of physical chemistry. B 20070712

• Laser photoexcitation of NAD(P)H induces reduction of P450 BM3 heme domain on the microsecond time scale.

  Journal of the American Chemical Society 20070523

• Potential anti-inflammatory actions of the elmiric (lipoamino) acids.

  Bioorganic & medicinal chemistry 20070515

• Conformational dynamics of substrate in the active site of cytochrome P450 BM-3/NPG complex: insights from NMR order parameters.

  Journal of the American Chemical Society 20070124

• Conformational equilibrium of cytochrome P450 BM-3 complexed with N-palmitoylglycine: a replica exchange molecular dynamics study.

  Journal of the American Chemical Society 20060503

• Structure-guided recombination creates an artificial family of cytochromes P450.

  PLoS biology 20060501

• Observation of ligand binding to cytochrome P450 BM-3 by means of solid-state NMR spectroscopy.

  Journal of the American Chemical Society 20051012

• Thermal equilibrium of high- and low-spin forms of cytochrome P450 BM-3: repositioning of the substrate?

  Journal of the American Chemical Society 20051005

• Effects of feeding Spodoptera littoralis on lima bean leaves. I. Membrane potentials, intracellular calcium variations, oral secretions, and regurgitate components.

  Plant physiology 20040401

• HPLC analysis of fatty acyl-glycine in the aqueous methanesulfonic acid hydrolysates of N-terminally fatty acylated peptides.

  Biological & pharmaceutical bulletin 20030801

• Pivotal role of water in the mechanism of P450BM-3.

  Biochemistry 20011113