2456-81-7 | 4-Pyrrolidinopyridine

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$9.00	$7.00
25g	98%	in stock	$17.00	$12.00
100g	98%	in stock	$55.00	$39.00

Description

• Catalog Number: AB24930
• Chemical Name: 4-Pyrrolidinopyridine
• CAS Number: 2456-81-7
• Molecular Formula: C9H12N2
• Molecular Weight: 148.205
• MDL Number: MFCD00006415
• SMILES: C1CCN(C1)c1ccncc1

Computed Properties

• Complexity: 113
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• XLogP3: 1.5

Upstream Synthesis Route

4-Pyrrolidinopyridine is a versatile organic compound widely used in chemical synthesis as a strong nucleophilic base. Its unique structure and properties make it an essential reagent in various reactions, particularly in the field of organic synthesis. One of the key applications of 4-Pyrrolidinopyridine is its role as a catalyst in the construction of carbon-carbon and carbon-heteroatom bonds. It acts as a highly efficient base in organic transformations such as acylation, alkylation, and condensation reactions. In addition, 4-Pyrrolidinopyridine is commonly used in the preparation of pharmaceuticals, agrochemicals, and other fine chemicals due to its ability to facilitate complex molecular rearrangements and functional group interconversions. Its broad utility in promoting chemical reactions with high efficiency and selectivity has made 4-Pyrrolidinopyridine a valuable tool in modern synthetic chemistry.

Literature

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  Journal of the American Chemical Society 20120606

• 1H and 13C NMR spectral assignments of pyridinium salts linked to a N-9 or N-3 adenine moiety.

  Magnetic resonance in chemistry : MRC 20120601

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  Journal of the American Chemical Society 20111214

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  Journal of the American Chemical Society 20110907

• A dual-catalysis/anion-binding approach to the kinetic resolution of allylic amines.

  Organic letters 20110506

• Tetra-μ-benzoato-bis-{[4-(pyrrolidin-1-yl)pyridine]zinc(II)}.

  Acta crystallographica. Section E, Structure reports online 20100101

• A rapid and sensitive method for the simultaneous analysis of aliphatic and polar molecules containing free carboxyl groups in plant extracts by LC-MS/MS.

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  Organic letters 20080605

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  Journal of the American Chemical Society 20080402

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  Journal of the American Chemical Society 20071024

• Enhancement of ninhydrin- or DFO-treated latent fingerprints on thermal paper.

  Journal of forensic sciences 20070501

• Facile syntheses of acyl dihydroxyacetone phosphates and lysophosphatidic acids having different acyl groups.

  Journal of lipid research 20060801

• From uncharged to decacationic molecules: syntheses and spectroscopic properties of heteroarenium-substituted pyridines.

  Organic & biomolecular chemistry 20051021

• Alpha- and beta- aspartyl peptide ester formation via aspartimide ring opening.

  Journal of peptide science : an official publication of the European Peptide Society 20051001

• Kinetic resolution of sec-alcohols using a new class of readily assembled (S)-proline-derived 4-(pyrrolidino)-pyridine analogues.

  Organic & biomolecular chemistry 20050321

• L-Phe end-capped poly(L-lactide) as macroinitiator for the synthesis of poly(L-lactide)-B-poly(L-lysine) block copolymer.

  Biomacromolecules 20050101

• A facile preparation of 1-(6-hydroxyindol-1-yl)-2,2-dimethylpropan-1-one.

  Chemical & pharmaceutical bulletin 20030101

• Enantioselective addition of amines to ketenes catalyzed by a planar-chiral derivative of PPY: possible intervention of chiral Brønsted-acid catalysis.

  Journal of the American Chemical Society 20020828

• Enantioselective Staudinger synthesis of beta-lactams catalyzed by a planar-chiral nucleophile.

  Journal of the American Chemical Society 20020227