2459-05-4 | Fumaric acid monoethyl ester

Packsize	Purity	Availability	Price	Discounted Price
25g	98%	in stock	$10.00	$7.00
100g	98%	in stock	$35.00	$24.00
500g	98%	in stock	$146.00	$102.00

Description

• Catalog Number: AB25104
• Chemical Name: Fumaric acid monoethyl ester
• CAS Number: 2459-05-4
• Molecular Formula: C6H8O4
• Molecular Weight: 144.12532
• MDL Number: MFCD00002699
• SMILES: CCOC(=O)/C=C/C(=O)O
• NSC Number: 244252

Computed Properties

• Complexity: 159
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 0.2

Literature

• Photo-crosslinked networks prepared from fumaric acid monoethyl ester-functionalized poly(D,L-lactic acid) oligomers and N-vinyl-2-pyrrolidone for the controlled and sustained release of proteins.

  Acta biomaterialia 20121001

• Photo-crosslinked biodegradable hydrogels prepared from fumaric acid monoethyl ester-functionalized oligomers for protein delivery.

  Macromolecular bioscience 20120501

• Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).

  Bioorganic & medicinal chemistry letters 20110501

• Treatment of recurrent aphthous stomatitis with fumaric acid esters.

  Archives of dermatology 20110301

• Rapid photo-crosslinking of fumaric acid monoethyl ester-functionalized poly(trimethylene carbonate) oligomers for drug delivery applications.

  Journal of controlled release : official journal of the Controlled Release Society 20101001

• Creep-resistant elastomeric networks prepared by photocrosslinking fumaric acid monoethyl ester-functionalized poly(trimethylene carbonate) oligomers.

  Acta biomaterialia 20090601

• Fumaric acid monoethyl ester-functionalized poly(D,L-lactide)/N-vinyl-2-pyrrolidone resins for the preparation of tissue engineering scaffolds by stereolithography.

  Biomacromolecules 20090209

• Fumaric acid esters in necrobiosis lipoidica: results of a prospective noncontrolled study.

  The British journal of dermatology 20051001

• Preparation of biodegradable networks by photo-crosslinking lactide, epsilon-caprolactone and trimethylene carbonate-based oligomers functionalized with fumaric acid monoethyl ester.

  Biomaterials 20050601

• Preparation of hydrogels by photo-crosslinking of fumaric acid monoethyl ester (fame) functionalized oligomers.

  Journal of controlled release : official journal of the Controlled Release Society 20050103

• In vitro pharmacokinetics of anti-psoriatic fumaric acid esters.

  BMC pharmacology 20040101

• Presystemic metabolism and intestinal absorption of antipsoriatic fumaric acid esters.

  Biopharmaceutics & drug disposition 20030901

• Treatment of disseminated granuloma annulare with fumaric acid esters.

  BMC dermatology 20020101

• Successful treatment of recalcitrant cutaneous sarcoidosis with fumaric acid esters.

  BMC dermatology 20020101