2491-38-5 | 2-Bromo-4'-hydroxyacetophenone

Packsize	Purity	Availability	Price	Discounted Price
1g	90%	in stock	$13.00	$9.00
5g	90%	in stock	$15.00	$10.00
10g	90%	in stock	$20.00	$14.00
25g	90%	in stock	$45.00	$31.00
100g	90%	in stock	$129.00	$90.00
500g	90%	in stock	$510.00	$357.00

Description

• Catalog Number: AB26607
• Chemical Name: 2-Bromo-4'-hydroxyacetophenone
• CAS Number: 2491-38-5
• Molecular Formula: C8H7BrO2
• Molecular Weight: 215.044
• MDL Number: MFCD00072424
• SMILES: BrCC(=O)c1ccc(cc1)O

Computed Properties

• Complexity: 139
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 11
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 2
• XLogP3: 2.4

Upstream Synthesis Route

2-Bromo-4'-hydroxyacetophenone is a versatile compound commonly used in chemical synthesis as a key building block for the creation of various pharmaceuticals, agrochemicals, and organic compounds. Its unique structure allows for diverse functionalization and modification, making it an essential reagent in the production of complex organic molecules. In particular, 2-Bromo-4'-hydroxyacetophenone is frequently employed in the synthesis of drug intermediates, such as antiviral agents and anti-inflammatory compounds, due to its selective substitution patterns and reactivity. Additionally, this compound is utilized in the preparation of specialty chemicals and fine chemicals, enabling the development of novel materials and research compounds. Its role in chemical synthesis extends to the creation of advanced materials with specific properties, highlighting its significance in the field of organic chemistry.

Literature

• Preparation and photophysical properties of a caged kynurenine.

  Bioorganic & medicinal chemistry letters 20120415

• 2-Bromo-1-(4-hydroxy-phen-yl)ethanone.

  Acta crystallographica. Section E, Structure reports online 20091101

• Allergic contact dermatitis from a paper mill slimicide containing 2-bromo-4'-hydroxyacetophenone.

  American journal of contact dermatitis : official journal of the American Contact Dermatitis Society 20030301

• alpha-bromoacetophenone derivatives as neutral protein tyrosine phosphatase inhibitors: structure-Activity relationship.

  Bioorganic & medicinal chemistry letters 20021104

• Catalytic subunit of protein kinase A caged at the activating phosphothreonine.

  Journal of the American Chemical Society 20020717