25137-00-2 | (R)-Piperidine-3-carboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
250mg	98%	in stock	$7.00	$5.00
1g	98%	in stock	$10.00	$7.00
5g	98%	in stock	$40.00	$28.00
25g	98%	in stock	$180.00	$126.00
500g	98%	in stock	$3,558.00	$2,491.00

Description

• Catalog Number: AI45823
• Chemical Name: (R)-Piperidine-3-carboxylic acid
• CAS Number: 25137-00-2
• Molecular Formula: C6H11NO2
• Molecular Weight: 129.15704
• MDL Number: MFCD01630787
• SMILES: OC(=O)[C@@H]1CCCNC1

Computed Properties

• Complexity: 114
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -2.9

Literature

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  ChemMedChem 20100705

• Azetidine derivatives as novel gamma-aminobutyric acid uptake inhibitors: synthesis, biological evaluation, and structure-activity relationship.

  European journal of medicinal chemistry 20100601

• Synthesis and biological evaluation of aminomethylphenol derivatives as inhibitors of the murine GABA transporters mGAT1-mGAT4.

  European journal of medicinal chemistry 20081101

• Synthesis and biological evaluation of (R)-N-(diarylmethylthio/sulfinyl)ethyl/propyl-piperidine-3-carboxylic acid hydrochlorides as novel GABA uptake inhibitors.

  Bioorganic & medicinal chemistry letters 20070701

• Design, synthesis, and biological evaluation of the N-diarylalkenyl-piperidinecarboxylic acid derivatives as GABA uptake inhibitors (I).

  Bioorganic & medicinal chemistry letters 20060101

• Novel secoergoline derivatives inhibit both GABA and glutamate uptake in rat brain homogenates: synthesis, in vitro pharmacology, and modeling.

  Journal of medicinal chemistry 20041104

• Assay for nipecotic acid in small blood samples by gas chromatography-mass spectroscopy.

  Journal of pharmaceutical and biomedical analysis 20040310

• Delta-Aminolevulinic acid transport in murine mammary adenocarcinoma cells is mediated by beta transporters.

  British journal of cancer 20020812

• Protein prosthesis: a semisynthetic enzyme with a beta-peptide reverse turn.

  Journal of the American Chemical Society 20020724

• Pharmacological evidence for GABAergic regulation of specific behaviors in Drosophila melanogaster.

  Journal of neurobiology 20020215

• Action of 4-amino-2-fluorobutanoic acid and other structural analogues on gamma-aminobutyric acid transport by channel catfish brain.

  Journal of basic and clinical physiology and pharmacology 20020101