2516-47-4 | Cyclopropylmethanamine

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$13.00	$9.00
5g	95%	in stock	$45.00	$32.00
10g	95%	in stock	$83.00	$58.00
25g	95%	in stock	$136.00	$95.00
100g	95%	in stock	$463.00	$324.00

Description

• Catalog Number: AB27714
• Chemical Name: Cyclopropylmethanamine
• CAS Number: 2516-47-4
• Molecular Formula: C4H9N
• Molecular Weight: 71.121
• MDL Number: MFCD12407110
• SMILES: NCC1CC1

Computed Properties

• Complexity: 30.6
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 5
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1

Upstream Synthesis Route

Cyclopropylmethanamine is a versatile chemical compound commonly used in chemical synthesis. Its unique cyclopropyl group imparts structural rigidity and reactivity that make it valuable in the creation of specialized organic molecules. In organic synthesis, it serves as a key building block for the construction of various pharmaceuticals, agrochemicals, and materials. Its small, three-membered ring structure allows for spatial constraints that can be advantageous in designing molecules with specific stereochemistry or conformational preferences. Additionally, the presence of the primary amine functional group in cyclopropylmethanamine enables easy manipulation through various chemical transformations, such as acylation, alkylation, and condensation reactions. This compound's utility extends to the synthesis of heterocyclic compounds, amino acids, and chiral ligands, highlighting its significance in modern chemical research and development.

Literature

• 7-Benzyl-2-[(cyclo-propyl-meth-yl)amino]-3-phenyl-5,6,7,8-tetra-hydro-pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(3H)-one.

  Acta crystallographica. Section E, Structure reports online 20110801

• Analogs of the CLV3 peptide: synthesis and structure-activity relationships focused on proline residues.

  Plant & cell physiology 20110101

• Selective 5-hydroxytryptamine 2C receptor agonists derived from the lead compound tranylcypromine: identification of drugs with antidepressant-like action.

  Journal of medicinal chemistry 20090409

• Conformationally restricted homotryptamines. Part 4: Heterocyclic and naphthyl analogs of a potent selective serotonin reuptake inhibitor.

  Bioorganic & medicinal chemistry letters 20071015

• Effect of high-dose milnacipran in patients with depression.

  Neuropsychiatric disease and treatment 20071001

• A novel polyamine analog (SL-11093) inhibits growth of human prostate tumor xenografts in nude mice.

  Cancer chemotherapy and pharmacology 20030601