-
Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis.
Chemical research in toxicology 20150518
-
A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans.
Toxicological sciences : an official journal of the Society of Toxicology 20140101
-
Detection of 22 antiepileptic drugs by ultra-performance liquid chromatography coupled with tandem mass spectrometry applicable to routine therapeutic drug monitoring.
Biomedical chromatography : BMC 20121201
-
Insights into the novel hydrolytic mechanism of a diethyl 2-phenyl-2-(2-arylacetoxy)methyl malonate ester-based microsomal triglyceride transfer protein (MTP) inhibitor.
Chemical research in toxicology 20121015
-
The cost effectiveness of newer epilepsy treatments: a review of the literature on partial-onset seizures.
PharmacoEconomics 20121001
-
Shape-based reprofiling of FDA-approved drugs for the H₁ histamine receptor.
Journal of medicinal chemistry 20120823
-
Chemical properties of antiepileptic drugs (AEDs).
Advanced drug delivery reviews 20120701
-
Pharmacokinetic drug interactions between clobazam and drugs metabolized by cytochrome P450 isoenzymes.
Pharmacotherapy 20120401
-
Syntheses and evaluation of anticonvulsant activity of novel branched alkyl carbamates.
Journal of medicinal chemistry 20120322
-
Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice.
Pharmacological research 20120301
-
Prevalence of treated epilepsy in Korea based on national health insurance data.
Journal of Korean medical science 20120301
-
Weight-reducing side effects of the antiepileptic agents topiramate and zonisamide.
Handbook of experimental pharmacology 20120101
-
Clinical utility of adjunctive retigabine in partial onset seizures in adults.
Therapeutics and clinical risk management 20120101
-
Clinical decision support of therapeutic drug monitoring of phenytoin: measured versus adjusted phenytoin plasma concentrations.
BMC medical informatics and decision making 20120101
-
Recent progress in anticonvulsant drug research: strategies for anticonvulsant drug development and applications of antiepileptic drugs for non-epileptic central nervous system disorders.
Current topics in medicinal chemistry 20120101
-
The nervous system and metabolic dysregulation: emerging evidence converges on ketogenic diet therapy.
Frontiers in neuroscience 20120101
-
Analysis of selected anticonvulsants by high performance liquid chromatography-tandem mass spectrometry.
Methods in molecular biology (Clifton, N.J.) 20120101
-
New developments in the treatment of partial-onset epilepsy.
Neuropsychiatric disease and treatment 20120101
-
Efficacy and tolerability of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-oestradiol in a 24/4 regimen, in comparison to an oral contraceptive containing ethinylestradiol and drospirenone in a 21/7 regimen.
The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception 20111201
-
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
PLoS computational biology 20111201
-
Nitric oxide, epileptic seizures, and action of antiepileptic drugs.
CNS & neurological disorders drug targets 20111101
-
Development of a highly sensitive cytotoxicity assay system for CYP3A4-mediated metabolic activation.
Drug metabolism and disposition: the biological fate of chemicals 20110801
-
Gabapentin: An update of its pharmacological properties and therapeutic use in epilepsy.
Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110801
-
Antiepileptic drugs and the immune system.
Epilepsia 20110501
-
Rufinamide for the treatment of Lennox-Gastaut syndrome.
Expert opinion on pharmacotherapy 20110401
-
Management of seizures in Lennox-Gastaut syndrome.
Paediatric drugs 20110401
-
Depressogenic effects of medications: a review.
Dialogues in clinical neuroscience 20110301
-
From toxins targeting ligand gated ion channels to therapeutic molecules.
Toxins 20110301
-
Rhythmic delta activity represents a form of nonconvulsive status epilepticus in anti-NMDA receptor antibody encephalitis.
Epilepsy & behavior : E&B 20110201
-
Felbamate as an add-on therapy for refractory epilepsy.
The Cochrane database of systematic reviews 20110119
-
Low dose of bupropion significantly enhances the anticonvulsant activity of felbamate, lamotrigine and topiramate in mice.
European journal of pharmacology 20110115
-
Association of antiepileptic drugs with nontraumatic fractures: a population-based analysis.
Archives of neurology 20110101
-
Traditional and non-traditional treatments for autism spectrum disorder with seizures: an on-line survey.
BMC pediatrics 20110101
-
Management of provoked seizure.
Annals of Indian Academy of Neurology 20110101
-
Update on rufinamide in childhood epilepsy.
Neuropsychiatric disease and treatment 20110101
-
Treatment options for refractory and difficult to treat seizures: focus on vigabatrin.
Therapeutics and clinical risk management 20110101
-
Epilepsy, anti-epileptic drugs and bone health in children.
Journal of pediatric neurosciences 20110101
-
Prescribing medications in patients with decompensated liver cirrhosis.
International journal of hepatology 20110101
-
A comprehensive review of the literature on epilepsy in selected countries in emerging markets.
Neuropsychiatric disease and treatment 20110101
-
Comparison of the efficacy of carbamazepine, gabapentin and lamotrigine for neuropathic pain in rats.
Indian journal of pharmacology 20110101
-
Clobazam as an adjunctive therapy in treating seizures associated with Lennox-Gastaut syndrome.
Neuropsychiatric disease and treatment 20110101
-
Effect of Gentiana olivieri on experimental epilepsy models.
Pharmacognosy magazine 20110101
-
Rapid and sensitive LC-MS/MS method for determination of felbamate in mouse plasma and tissues and human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20101215
-
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Drug metabolism and disposition: the biological fate of chemicals 20101201
-
Use of antiepileptic drugs for hyperkinetic movement disorders.
Current neuropharmacology 20101201
-
'Epileptic encephalopathy' of infancy and childhood: electro-clinical pictures and recent understandings.
Current neuropharmacology 20101201
-
Antiepileptic drug interactions - principles and clinical implications.
Current neuropharmacology 20100901
-
Periodic lateralized epileptiform discharges: Do they represent an ictal pattern requiring treatment?
Epilepsy & behavior : E&B 20100701
-
Update on antithrombotic therapy for stroke prevention in atrial fibrillation.
Current treatment options in cardiovascular medicine 20100601
-
Efficacy of felbamate in the treatment of intractable pediatric epilepsy.
Pediatric neurology 20100601
-
Effect of propranolol on functional connectivity in autism spectrum disorder--a pilot study.
Brain imaging and behavior 20100601
-
Diverse antiepileptic drugs increase the ratio of background synaptic inhibition to excitation and decrease neuronal excitability in neurones of the rat entorhinal cortex in vitro.
Neuroscience 20100505
-
Medical management of Lennox-Gastaut syndrome.
CNS drugs 20100501
-
[Antiepileptic drugs in North America].
Brain and nerve = Shinkei kenkyu no shinpo 20100501
-
Recent advances in adjunctive therapy for epilepsy: focus on sodium channel blockers as third-generation antiepileptic drugs.
Drugs of today (Barcelona, Spain : 1998) 20100401
-
A novel HPLC method for quantification of 10 antiepileptic drugs or metabolites in serum/plasma using a monolithic column.
Therapeutic drug monitoring 20100201
-
Simultaneous HPLC-UV analysis of rufinamide, zonisamide, lamotrigine, oxcarbazepine monohydroxy derivative and felbamate in deproteinized plasma of patients with epilepsy.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201
-
Behavioral and cognitive effects of anti-epileptic drugs.
Discovery medicine 20100201
-
Development of multi-electrode array screening for anticonvulsants in acute rat brain slices.
Journal of neuroscience methods 20100115
-
Drug interactions involving the new second- and third-generation antiepileptic drugs.
Expert review of neurotherapeutics 20100101
-
[Therapeutic drug monitoring of felbamate].
Therapie 20100101
-
Management of refractory complex partial seizures: current state of the art.
Neuropsychiatric disease and treatment 20100101
-
[Felbamate crystalluria].
Annales de biologie clinique 20100101
-
Treating Lennox-Gastaut syndrome in epileptic pediatric patients with third-generation rufinamide.
Neuropsychiatric disease and treatment 20100101
-
Bioassay-guided evaluation of antinociceptive effect of N-salicyloyltryptamine: a behavioral and electrophysiological approach.
Journal of biomedicine & biotechnology 20100101
-
Genetic variations in human glutathione transferase enzymes: significance for pharmacology and toxicology.
Human genomics and proteomics : HGP 20100101
-
Lennox-Gastaut syndrome: An overview.
Journal of pediatric neurosciences 20100101
-
Advances in epilepsy: new perspectives on new-onset epilepsy, comorbidities, and pharmacotherapy.
F1000 medicine reports 20100101
-
Selected pharmacokinetic issues of the use of antiepileptic drugs and parenteral nutrition in critically ill patients.
Nutrition journal 20100101
-
Weight-gain in psychiatric treatment: risks, implications, and strategies for prevention and management.
Mens sana monographs 20100101
-
Antiepileptic drugs and suicidality.
Drug, healthcare and patient safety 20100101
-
The interaction between clopidogrel and proton pump inhibitors (PPI): is there any clinical relevance?
Clinical pharmacology : advances and applications 20100101
-
Neuronal potassium channel openers in the management of epilepsy: role and potential of retigabine.
Clinical pharmacology : advances and applications 20100101
-
Medical treatment of pediatric urolithiasis.
Pediatric nephrology (Berlin, Germany) 20091101
-
Long-term use of felbamate: clinical outcomes and effect of age and concomitant antiepileptic drug use on its clearance.
Epilepsia 20091101
-
Metabolomics in drug intolerance.
Current drug metabolism 20091101
-
Iatrogenic QT Abnormalities and Fatal Arrhythmias: Mechanisms and Clinical Significance.
Current cardiology reviews 20090801
-
Treatment of Lennox-Gastaut syndrome.
The Cochrane database of systematic reviews 20090708
-
Antiepileptic drug monotherapy: the initial approach in epilepsy management.
Current neuropharmacology 20090601
-
Transitional polytherapy: tricks of the trade for monotherapy to monotherapy AED conversions.
Current neuropharmacology 20090601
-
Truly 'rational' polytherapy: maximizing efficacy and minimizing drug interactions, drug load, and adverse effects.
Current neuropharmacology 20090601
-
Minimizing AED adverse effects: improving quality of life in the interictal state in epilepsy care.
Current neuropharmacology 20090601
-
VEP indices of cortical lateral interactions in epilepsy treatment.
Vision research 20090501
-
Allopregnanolone (3alpha-hydroxy-5alpha-pregnan-20-one) derivatives with a polar chain in position 16alpha: synthesis and activity.
Journal of medicinal chemistry 20090409
-
[Empirical evidence for the use of anticonvulsants in personality disorders].
Fortschritte der Neurologie-Psychiatrie 20090301
-
Onset of action and seizure control in Lennox-Gaustaut syndrome: focus on rufinamide.
Therapeutics and clinical risk management 20090101
-
Current trends in the treatment of infantile spasms.
Neuropsychiatric disease and treatment 20090101
-
Neurological and neurobehavioral assessment of experimental subarachnoid hemorrhage.
BMC neuroscience 20090101
-
Symptomatic hypocalcemia in an epileptic child treated with valproic acid plus lamotrigine: a case report.
Cases journal 20090101
-
Update on the management of Lennox-Gastaut syndrome with a focus on rufinamide.
Neuropsychiatric disease and treatment 20090101
-
Drug-induced hematologic syndromes.
Advances in hematology 20090101
-
Felbamate in an adult population with severe refractory epilepsy.
Irish medical journal 20090101
-
Anticonvulsant Activity of Argyreia speciosa in Mice.
Indian journal of pharmaceutical sciences 20090101
-
ATP signalling in epilepsy.
Purinergic signalling 20081201
-
Mechanistic and pharmacologic aspects of status epilepticus and its treatment with new antiepileptic drugs.
Epilepsia 20081201
-
Treatment of Lennox-Gastaut syndrome: overview and recent findings.
Neuropsychiatric disease and treatment 20081201
-
Cross-sensitivity of skin rashes with antiepileptic drug use.
Neurology 20081104
-
New antiepileptic drugs in pediatric epilepsy.
Brain & development 20081001
-
Efficacy and safety of felbamate in children under 4 years of age: a retrospective chart review.
European journal of neurology 20080901
-
Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose.
Chemical research in toxicology 20080901
-
Cognitive effects of antiepileptic drugs.
Journal of clinical neurology (Seoul, Korea) 20080901
-
Approaches to treatment of type 2 diabetes.
Diabetes care 20080801
-
Greater response to placebo in children than in adults: a systematic review and meta-analysis in drug-resistant partial epilepsy.
PLoS medicine 20080801
-
Drug interactions between chemotherapeutic regimens and antiepileptics.
Clinical therapeutics 20080801
-
Tiagabine: efficacy and safety in partial seizures - current status.
Neuropsychiatric disease and treatment 20080801
-
Drug monitoring and toxicology: a simple procedure for the monitoring of felbamate by HPLC-UV detection.
Journal of analytical toxicology 20080601
-
Molecular determinants of the anticonvulsant felbamate binding site in the N-methyl-D-aspartate receptor.
Journal of medicinal chemistry 20080327
-
GABA(A) receptors in normal development and seizures: friends or foes?
Current neuropharmacology 20080301
-
Monotherapy for partial epilepsy: focus on levetiracetam.
Neuropsychiatric disease and treatment 20080201
-
Interactions of MRZ 2/576 with felbamate, lamotrigine, oxcarbazepine and topiramate in the mouse maximal electroshock-induced seizure model.
Pharmacology 20080101
-
Lennox gastaut syndrome, review of the literature and a case report.
Head & face medicine 20080101
-
Use of second-generation antiepileptic drugs in the pediatric population.
Paediatric drugs 20080101
-
Improvement in depressive symptoms with felbamate: a case report.
Primary care companion to the Journal of clinical psychiatry 20080101
-
Pharmacological management of epilepsy: recent advances and future prospects.
Drugs 20080101
-
The role of NMDA receptor subtypes in short-term plasticity in the rat entorhinal cortex.
Neural plasticity 20080101
-
Seizure control in patients with epilepsy: the physician vs. medication factors.
BMC health services research 20080101
-
[Endocrine effects of antiepileptic drugs].
Przeglad lekarski 20080101
-
[Effects of antiepileptic drugs on immune system].
Przeglad lekarski 20080101
-
Effects of new antiepileptic drugs and progabide on the mitogen-induced proliferative activity of mouse splenocytes.
Pharmacological reports : PR 20080101
-
Modifications of antiepileptic drugs for improved tolerability and efficacy.
Perspectives in medicinal chemistry 20080101
-
[Treatment of epilepsy with third-line antiepileptic drugs: felbamate, tiagabine, and sulthiame].
Der Nervenarzt 20071201
-
Felbamate but not phenytoin or gabapentin reduces glutamate release by blocking presynaptic NMDA receptors in the entorhinal cortex.
Epilepsy research 20071201
-
Topiramate in the treatment of partial and generalized epilepsy.
Neuropsychiatric disease and treatment 20071201
-
Development of membrane electrodes for selective determination of some antiepileptic drugs in pharmaceuticals, plasma and urine.
Analytical and bioanalytical chemistry 20071101
-
Treatment of drop attacks in Coffin-Lowry syndrome with the use of sodium oxybate.
Pediatric neurology 20071101
-
Assessment of antiepileptic drugs as substrates for canine P-glycoprotein.
American journal of veterinary research 20071001
-
Extracellular proton-modulated pore-blocking effect of the anticonvulsant felbamate on NMDA channels.
Biophysical journal 20070915
-
Characterization of the gating conformational changes in the felbamate binding site in NMDA channels.
Biophysical journal 20070715
-
Influence of levetiracetam on the anticonvulsant efficacy of conventional antiepileptic drugs against audiogenic seizures in DBA/2 mice.
Epilepsy research 20070701
-
Antiepileptic drugs and visual function.
Pediatric neurology 20070601
-
Comparison and predictors of rash associated with 15 antiepileptic drugs.
Neurology 20070515
-
A new look at the second-generation antiepileptic drugs: a decade of experience.
The neurologist 20070501
-
Levetiracetam and felbamate interact both pharmacodynamically and pharmacokinetically: an isobolographic analysis in the mouse maximal electroshock model.
Epilepsia 20070401
-
Evaluation of felbamate and other antiepileptic drug toxicity potential based on hepatic protein covalent binding and gene expression.
Chemical research in toxicology 20070401
-
NMDA receptor antagonist felbamate reduces behavioral deficits and blood-brain barrier permeability changes after experimental subarachnoid hemorrhage in the rat.
Journal of neurotrauma 20070401
-
Comparison of cognitive effects of lamotrigine and oxcarbazepine in epilepsy patients.
Journal of clinical neurology (Seoul, Korea) 20070301
-
[Psychotropic drug-induced change of weight: a review].
Fortschritte der Neurologie-Psychiatrie 20070201
-
Psychiatric and behavioral side effects of the newer antiepileptic drugs in adults with epilepsy.
Epilepsy & behavior : E&B 20070201
-
[Newer antiepileptic drugs].
No to shinkei = Brain and nerve 20070201
-
[Newer antiepileptic drugs].
Brain and nerve = Shinkei kenkyu no shinpo 20070201
-
Role of rufinamide in the management of Lennox-Gastaut syndrome (childhood epileptic encephalopathy).
Neuropsychiatric disease and treatment 20070201
-
Progress report on new antiepileptic drugs: a summary of the Eigth Eilat Conference (EILAT VIII).
Epilepsy research 20070101
-
Targets for antiepileptic drugs in the synapse.
Medical science monitor : international medical journal of experimental and clinical research 20070101
-
Discovery of antiepileptic drugs.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101
-
Fluorofelbamate.
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101
-
Mechanisms of action of antiepileptic drugs.
International review of neurobiology 20070101
-
Negative effects of antiepileptic drugs on mood in patients with epilepsy.
Drug safety 20070101
-
[New antiepileptics in development].
Pharmazie in unserer Zeit 20070101
-
Enhanced glutamatergic transmission reduces the anticonvulsant potential of lamotrigine but not of felbamate against tonic-clonic seizures.
Pharmacological reports : PR 20070101
-
Weight issues for people with epilepsy--a review.
Epilepsia 20070101
-
Effects of some new antiepileptic drugs and progabide on glucocorticoid receptor-mediated gene transcription in LMCAT cells.
Pharmacological reports : PR 20070101
-
Optimizing therapy of seizures in patients with renal or hepatic dysfunction.
Neurology 20061226
-
Optimizing therapy of seizures in women who use oral contraceptives.
Neurology 20061226
-
Felbamate is a subunit selective modulator of recombinant gamma-aminobutyric acid type A receptors expressed in Xenopus oocytes.
European journal of pharmacology 20061215
-
Psychopharmacology of topiramate: from epilepsy to bipolar disorder.
Neuropsychiatric disease and treatment 20061201
-
Felbamate: consensus of current clinical experience.
Epilepsy research 20061001
-
Lamotrigine as a possible cause of QRS prolongation in a patient with known seizure disorder.
CJEM 20060901
-
Topiramate monotherapy in infantile spasm.
Yonsei medical journal 20060831
-
Enhancement of brain kynurenic acid production by anticonvulsants--novel mechanism of antiepileptic activity?
European journal of pharmacology 20060717
-
Diverse mechanisms of antiepileptic drugs in the development pipeline.
Epilepsy research 20060601
-
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
-
Clinically relevant drug interactions with antiepileptic drugs.
British journal of clinical pharmacology 20060301
-
Interactions between antiepileptic and antipsychotic drugs.
Drug safety 20060101
-
Behavioral effects of ketamine and toxic interactions with psychostimulants.
BMC neuroscience 20060101
-
Clinical pharmacokinetics of new-generation antiepileptic drugs at the extremes of age.
Clinical pharmacokinetics 20060101
-
An epidemiological study on anemia among institutionalized people with intellectual and/or motor disability with special reference to its frequency, severity and predictors.
BMC public health 20060101
-
Pharmacokinetic variability of newer antiepileptic drugs: when is monitoring needed?
Clinical pharmacokinetics 20060101
-
Influence of NG-nitro-L-arginine on the anticonvulsant and acute adverse effects of some newer antiepileptic drugs in the maximal electroshock-induced seizures and chimney test in mice.
Pharmacological reports : PR 20060101
-
Simultaneous liquid chromatographic determination of lamotrigine, oxcarbazepine monohydroxy derivative and felbamate in plasma of patients with epilepsy.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051215
-
Alteration of thyroid hormone homeostasis by antiepileptic drugs in humans: involvement of glucuronosyltransferase induction.
European journal of clinical pharmacology 20051201
-
Household disposal of pharmaceuticals as a pathway for aquatic contamination in the United kingdom.
Environmental health perspectives 20051201
-
Stability and comparative metabolism of selected felbamate metabolites and postulated fluorofelbamate metabolites by postmitochondrial suspensions.
Chemical research in toxicology 20051201
-
Pharmacokinetic variability of new antiepileptic drugs at different ages.
Therapeutic drug monitoring 20051201
-
The pharmacokinetics and interactions of new antiepileptic drugs: an overview.
Therapeutic drug monitoring 20051201
-
Induction of endogenous pathways by antiepileptics and clinical implications.
Fundamental & clinical pharmacology 20051001
-
Effect of antiepileptic drug comedication on lamotrigine clearance.
Archives of neurology 20050901
-
Effects of anticonvulsants on soman-induced epileptiform activity in the guinea-pig in vitro hippocampus.
European journal of pharmacology 20050822
-
Prediction of genotoxicity of chemical compounds by statistical learning methods.
Chemical research in toxicology 20050601
-
NMDA/NR2B selective antagonists in the treatment of ischemic brain injury.
Current drug targets. CNS and neurological disorders 20050401
-
Interaction between lamotrigine and felbamate in the maximal electroshock-induced seizures in mice: an isobolographic analysis.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050301
-
Felbamate reduces hormone release and locomotor hypoactivity induced by repeated stress of social defeat in mice.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20050301
-
Pharmacodynamic and pharmacokinetic interaction studies of loreclezole with felbamate, lamotrigine, topiramate, and oxcarbazepine in the mouse maximal electroshock seizure model.
Epilepsia 20050301
-
Analysis of antiepileptic drugs in biological fluids by means of electrokinetic chromatography.
Electrophoresis 20050201
-
Mechanisms of action of antiepileptic drugs.
Current topics in medicinal chemistry 20050101
-
Bupropion-induced convulsions: preclinical evaluation of antiepileptic drugs.
Epilepsy research 20050101
-
Acute felbamate overdose with crystalluria.
Clinical toxicology (Philadelphia, Pa.) 20050101
-
Ion channels and epilepsy.
Current pharmaceutical design 20050101
-
[Pharmacokinetic mechanisms underlying resistance in psychopharmacological treatment. The role of P-glycoprotein].
Vertex (Buenos Aires, Argentina) 20050101
-
[The effect of MDR1 gene polymorphism in the pathogenesis and the treatment of drug-resistant epilepsy].
Neurologia i neurochirurgia polska 20050101
-
Management of Landau-Kleffner syndrome.
Paediatric drugs 20050101
-
Profile of anticonvulsant activity and neuroprotective effects of novel and potential antiepileptic drugs--an update.
Pharmacological reports : PR 20050101
-
[Therapies for Lennox-Gastaut syndrome].
Srpski arhiv za celokupno lekarstvo 20050101
-
[Current pharmacotherapy of epilepsy in adults].
Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg 20050101
-
Investigating the role of 2-phenylpropenal in felbamate-induced idiosyncratic drug reactions.
Chemical research in toxicology 20041201
-
Efficacy and tolerability of the new antiepileptic drugs: comparison of two recent guidelines.
The Lancet. Neurology 20041001
-
Isobolographic and subthreshold analysis of interactions among felbamate and four conventional antiepileptic drugs in pentylenetetrazole-induced seizures in mice.
Epilepsia 20041001
-
Side effects of antiepileptics--a review.
Pain practice : the official journal of World Institute of Pain 20040901
-
Preclinical profile of combinations of some second-generation antiepileptic drugs: an isobolographic analysis.
Epilepsia 20040801
-
Pharmacodynamic interaction studies with topiramate in the pentylenetetrazol and maximal electroshock seizure models.
Seizure 20040701
-
[Treatment protocol for long-term anti-epilepsy drugs in adults with refractory partial epilepsy].
Revue neurologique 20040601
-
Regulation of cellular plasticity and resilience by mood stabilizers: the role of AMPA receptor trafficking.
Dialogues in clinical neuroscience 20040601
-
Effect of felbamate and its combinations with conventional antiepileptics in amygdala-kindled rats.
Pharmacology, biochemistry, and behavior 20040501
-
Adverse effects of new antiepileptic drugs.
Drugs of today (Barcelona, Spain : 1998) 20040401
-
[Drug interactions with antiepileptic agents].
Wiener klinische Wochenschrift 20040227
-
A new linker for glucuronylated anticancer prodrugs.
Bioorganic & medicinal chemistry 20040215
-
The new antiepileptic drugs: scientific review.
JAMA 20040204
-
Use-dependent inhibition of the N-methyl-D-aspartate currents by felbamate: a gating modifier with selective binding to the desensitized channels.
Molecular pharmacology 20040201
-
Influence of carbenoxolone on the anticonvulsant efficacy of conventional antiepileptic drugs against audiogenic seizures in DBA/2 mice.
European journal of pharmacology 20040119
-
Behavioural effects of the newer antiepileptic drugs: an update.
Expert opinion on drug safety 20040101
-
Treatment of partial seizures in childhood : an overview.
CNS drugs 20040101
-
Effects of seven clinically important antiepileptic drugs on inhibitory glycine receptor currents in hippocampal neurons.
Epilepsy research 20040101
-
New antiepileptic agents.
Pediatric dentistry 20040101
-
Is there any future for felbamate treatment?
Polish journal of pharmacology 20040101
-
Pharmacologic treatment of the catastrophic epilepsies.
Epilepsia 20040101
-
Significance of MDR1 and multiple drug resistance in refractory human epileptic brain.
BMC medicine 20040101
-
Influence of felbamate on selected central effects of ethanol in experimental animals.
Acta poloniae pharmaceutica 20040101
-
Progress report on new antiepileptic drugs: a summary of the Seventh Eilat Conference (EILAT VII).
Epilepsy research 20040101
-
Therapeutic drug monitoring of old and newer anti-epileptic drugs.
Clinical chemistry and laboratory medicine 20040101
-
Effect of lamotrigine combined with felbamate on the horizontal (ambulatory) activity in mice.
Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20040101
-
[Anticonvulsive activity of antiepileptic drugs and quantum-chemical modelling of their interaction with GABA(A) receptor].
Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101
-
Treatment of refractory primary generalized epilepsy.
Reviews in neurological diseases 20040101
-
Brain access and anticonvulsant efficacy of carbamazepine, lamotrigine, and felbamate in ABCC2/MRP2-deficient TR- rats.
Epilepsia 20031201
-
Epilepsy and adolescents.
Panminerva medica 20031201
-
Infantile spasms.
Expert opinion on pharmacotherapy 20031101
-
Effects of antiepileptic drugs on refractory seizures in the intact immature corticohippocampal formation in vitro.
Epilepsia 20031101
-
Relationship between extent of inhibition and inhibitor dose: literature evaluation based on the metabolism and transport drug interaction database.
Current drug metabolism 20031001
-
Is the interaction between felbamate and valproate against seizures induced by 4-aminopyridine and pentylenetetrazole in mice beneficial?
Pharmacological research 20030801
-
Synthesis and anticonvulsant activity of novel bicyclic acidic amino acids.
Journal of medicinal chemistry 20030703
-
In vivo CYP3A4 heteroactivation is a possible mechanism for the drug interaction between felbamate and carbamazepine.
The Journal of pharmacology and experimental therapeutics 20030601
-
Therapeutic drug monitoring of the newer antiepileptic drugs.
Therapeutic drug monitoring 20030601
-
Interactions of tiagabine with some antiepileptics in the maximal electroshock in mice.
Pharmacology, biochemistry, and behavior 20030501
-
The ideal pharmacokinetic properties of an antiepileptic drug: how close does levetiracetam come?
Epileptic disorders : international epilepsy journal with videotape 20030501
-
Synergistic interaction between felbamate and lamotrigine against seizures induced by 4-aminopyridine and pentylenetetrazole in mice.
European journal of pharmacology 20030328
-
[New epileptic treatments. Current modalities and their utilization].
Presse medicale (Paris, France : 1983) 20030308
-
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Neuroscience letters 20030102
-
Drug treatment of epilepsy in elderly people: focus on valproic Acid.
Drugs & aging 20030101
-
Interlaboratory variability in the quantification of new generation antiepileptic drugs based on external quality assessment data.
Epilepsia 20030101
-
Pharmacogenetics--the horizon.
Reviews in gastroenterological disorders 20030101
-
Selection criteria for the clinical use of the newer antiepileptic drugs.
CNS drugs 20030101
-
Clinical care of pregnant women with epilepsy: neural tube defects and folic acid supplementation.
Epilepsia 20030101
-
Treatment of Lennox-Gastaut syndrome.
The Cochrane database of systematic reviews 20030101
-
Effect of antiepileptic drugs on bodyweight: overview and clinical implications for the treatment of epilepsy.
CNS drugs 20030101
-
Influence of felbamate on the antinociceptive action of morphine, metamizol and indomethacin in mice.
Acta poloniae pharmaceutica 20030101
-
Influence of some convulsant agents on the protective activity of a novel antiepileptic drug, felbamate, against maximal electroshock in mice.
Polish journal of pharmacology 20030101
-
Rapid and simple high-performance liquid chromatographic determination of felbamate in serum.
Acta poloniae pharmaceutica 20030101
-
Antiepileptic drug therapy for adults: when to initiate and how to choose.
Mayo Clinic proceedings 20021201
-
Mechanisms of idiosyncratic drug reactions: the case of felbamate.
Chemico-biological interactions 20021110
-
Reactivity of atropaldehyde, a felbamate metabolite in human liver tissue in vitro.
Chemico-biological interactions 20021110
-
Polytherapy in epilepsy: the experimental evidence.
Epilepsy research 20021101
-
New antiepileptic drug therapies.
Neurologic clinics 20021101
-
Anticonvulsant and antiepileptogenic effects of fluorofelbamate in experimental status epilepticus.
Seizure 20021001
-
Vagus nerve stimulation in a case of epilepsy with CSWSS: respiratory side effects during sleep.
Epilepsia 20021001
-
New antiepileptic drugs in childhood.
Panminerva medica 20020901
-
[Monitoring serum levels of new antiepileptics].
Revista de neurologia 20020901
-
P-Glycoprotein-mediated efflux of phenobarbital, lamotrigine, and felbamate at the blood-brain barrier: evidence from microdialysis experiments in rats.
Neuroscience letters 20020726
-
Interaction between human serum albumin and the felbamate metabolites 4-Hydroxy-5-phenyl-[1,3]oxazinan-2-one and 2-phenylpropenal.
Chemical research in toxicology 20020601
-
[New antiepileptic drugs: new therapeutic options].
Revue neurologique 20020501
-
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.
The Journal of biological chemistry 20020419
-
Some common issues in the use of antiepileptic drugs.
Seminars in neurology 20020301
-
New antiepileptic drugs.
The neurologist 20020301
-
Marketed new antiepileptic drugs: are they better than old-generation agents?
Therapeutic drug monitoring 20020201
-
New antiepileptic drugs: review on drug interactions.
Therapeutic drug monitoring 20020201
-
Mechanisms underlying the nociception and paw oedema caused by injection of glutamate into the mouse paw.
Brain research 20020111
-
Felbamate-induced apoptosis of hematopoietic cells is mediated by redox-sensitive and redox-independent pathways.
Epilepsy research 20020101
-
Anticonvulsants: aspects of their mechanisms of action.
European journal of pain (London, England) 20020101
-
Pediatric partial and generalized seizures.
Journal of child neurology 20020101
-
Interactions between antiepileptic drugs and hormonal contraception.
CNS drugs 20020101
-
Medical treatment of patients with infantile spasms.
Clinical neuropharmacology 20020101
-
Antiepileptic drugs and agents that inhibit voltage-gated sodium channels prevent NMDA antagonist neurotoxicity.
Molecular psychiatry 20020101
-
Anticonvulsant drug hypersensitivity.
Journal of investigational allergology & clinical immunology 20020101
-
Pharmacological characterization of the 6 Hz psychomotor seizure model of partial epilepsy.
Epilepsy research 20011201
-
Clinical pharmacology and therapeutic use of the new antiepileptic drugs.
Fundamental & clinical pharmacology 20011201
-
The long-term use of felbamate in children with severe refractory epilepsy.
Epilepsy research 20011101
-
The NMDA receptor complex: a promising target for novel antiepileptic strategies.
Current medicinal chemistry 20010901
-
Newer antiepileptic drugs: advantages and disadvantages.
Brain & development 20010801
-
The chemistry, toxicology, and identification in rat and human urine of 4-hydroxy-5-phenyl-1,3-oxazaperhydroin-2-one: a reactive metabolite in felbamate bioactivation.
Chemical research in toxicology 20010801
-
Treatment of partial seizures and seizure-like activity with felbamate in six dogs.
The Journal of small animal practice 20010801
-
Advances in the treatment of epilepsy.
American family physician 20010701
-
The role of new antiepileptic drugs.
The American journal of managed care 20010701
-
Role of glutathione S-transferases A1-1, M1-1, and P1-1 in the detoxification of 2-phenylpropenal, a reactive felbamate metabolite.
Chemical research in toxicology 20010501
-
Felbamate urolithiasis.
Epilepsia 20010501
-
Monotherapy trials: presurgical studies.
Epilepsy research 20010501
-
Second generation anticonvulsant medications: their use in children.
The Journal of school nursing : the official publication of the National Association of School Nurses 20010401
-
Influence of retigabine on the anticonvulsant activity of some antiepileptic drugs against audiogenic seizures in DBA/2 mice.
Naunyn-Schmiedeberg's archives of pharmacology 20010301
-
[Antiepileptic drugs and neuropathic pain].
Revista de neurologia 20010201
-
Progress report on new antiepileptic drugs: a summary of the Fifth Eilat Conference (EILAT V).
Epilepsy research 20010101
-
[Controversies about the new anti-epileptic drugs].
Revista de neurologia 20010101
-
Pharmacologic management of epilepsy in the elderly.
Journal of the American Pharmaceutical Association (Washington,D.C. : 1996) 20010101
-
Felbamate, gabapentin and topiramate as adjuvant antiepileptic drugs in experimental models of epilepsy.
Polish journal of pharmacology 20010101
-
[New antiepileptic drugs in childhood epilepsies: indications and limits].
Epileptic disorders : international epilepsy journal with videotape 20010101
-
[West syndrome--new therapeutic approach].
Srpski arhiv za celokupno lekarstvo 20010101
-
A self-complementary, self-assembling microsphere system: application for intravenous delivery of the antiepileptic and neuroprotectant compound felbamate.
Journal of pharmaceutical sciences 20000701
-
Felbamate block of recombinant N-methyl-D-aspartate receptors: selectivity for the NR2B subunit.
Epilepsy research 20000301
-
Felbamate in experimental model of status epilepticus.
Epilepsia 20000201
-
Preclinical evaluation of newly approved and potential antiepileptic drugs against cocaine-induced seizures.
The Journal of pharmacology and experimental therapeutics 19990901
-
Subtype-selective antagonism of N-methyl-D-aspartate receptors by felbamate: insights into the mechanism of action.
The Journal of pharmacology and experimental therapeutics 19990501
-
Effects of anti-epileptic drugs on glutamine synthetase activity in mouse brain.
British journal of pharmacology 19990401
-
Acute, subchronic, and chronic toxicity studies with felbamate, 2-phenyl-1,3-propanediol dicarbamate.
Toxicological sciences : an official journal of the Society of Toxicology 19981001
-
Excitatory amino acid antagonists alleviate convulsive and toxic properties of lindane in mice.
Pharmacology & toxicology 19980301
-
Effects of new anticonvulsant medications on porphyrin synthesis in cultured liver cells: potential implications for patients with acute porphyria.
Neurology 19970701
-
Antagonism of convulsions but failure to enhance GABA(A) receptor function by felbamate in mice tolerant to diazepam.
Neurochemical research 19970601
-
Lamotrigine pharmacokinetics in patients receiving felbamate.
Epilepsy research 19970401
-
Felbamate decreases synaptic transmission in the CA1 region of rat hippocampal slices.
The Journal of pharmacology and experimental therapeutics 19961201
-
Anticonvulsant activity of 5,7DCKA, NBQX, and felbamate against some chemoconvulsants in DBA/2 mice.
Pharmacology, biochemistry, and behavior 19961001
-
Felbamate protects CA1 neurons from apoptosis in a gerbil model of global ischemia.
Stroke 19960701
-
Effects of felbamate on muscarinic and metabotropic-glutamate agonist-mediated responses and magnesium-free or 4-aminopyridine-induced epileptiform activity in guinea pig olfactory cortex neurons in vitro.
The Journal of pharmacology and experimental therapeutics 19960601
-
The effect of age on the apparent clearance of felbamate: a retrospective analysis using nonlinear mixed-effects modeling.
Therapeutic drug monitoring 19960201
-
Neuropsychiatric side effects related to treatment with felbamate.
The Journal of neuropsychiatry and clinical neurosciences 19960101
-
Excitoprotective effect of felbamate in cultured cortical neurons.
Brain research 19951224
-
The severity of naloxone-precipitated opiate withdrawal is attenuated by felbamate, a possible glycine antagonist.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 19951201
-
Felbamate modulates the strychnine-insensitive glycine receptor.
Epilepsy research 19950101
-
Felbamate displays in vitro antiepileptic effects as a broad spectrum excitatory amino acid receptor antagonist.
European journal of pharmacology 19941227
-
Felbamate antagonizes isoniazid- and FG 7142-induced reduction of GABAA receptor function in mouse brain.
European journal of pharmacology 19941124
-
Felbamate, an anti-convulsive drug, has anti-parkinsonian potential in rats.
Neuroscience letters 19940926
-
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice.
European journal of pharmacology 19940901
-
Felbamate, a novel antiepileptic agent, does not affect cognition in rodents.
Behavioural pharmacology 19940601
-
Comparative effects of felbamate and other compounds on N-methyl-D-aspartic acid-induced convulsions and lethality in mice.
Pharmacological research 19940101
-
Posthypoxic treatment with felbamate is neuroprotective in a rat model of hypoxia-ischemia.
Neurology 19931101
-
Effects of felbamate and other anticonvulsant drugs in two models of status epilepticus in the rat.
Research communications in chemical pathology and pharmacology 19930301
-
Effects of anticonvulsant drugs on 4-aminopyridine-induced seizures in mice.
Epilepsy research 19920301
-
Felbamate for partial seizures: results of a controlled clinical trial.
Neurology 19911101
-
Interaction of felbamate and diazepam against maximal electroshock seizures and chemoconvulsants in mice.
Pharmacology, biochemistry, and behavior 19910901
-
The effect of chronic felbamate administration on anticonvulsant activity and hepatic drug-metabolizing enzymes in mice and rats.
Epilepsia 19870101
-
Comparative anticonvulsant activity and neurotoxicity of felbamate and four prototype antiepileptic drugs in mice and rats.
Epilepsia 19860101