-
Formation mechanism of a new carbamazepine/malonic acid cocrystal polymorph.
International journal of pharmaceutics 20120715
-
Olfactomedin-4 is a glycoprotein secreted into mucus in active IBD.
Journal of Crohn's & colitis 20120501
-
First and second generation γ-secretase modulators (GSMs) modulate amyloid-β (Aβ) peptide production through different mechanisms.
The Journal of biological chemistry 20120406
-
5-(Prop-2-yn-yl)-5H-dibenzo[b,f]azepine.
Acta crystallographica. Section E, Structure reports online 20120401
-
A multiparametric approach to monitor the effects of γ-secretase inhibition along the whole intestinal tract.
Disease models & mechanisms 20120101
-
Relationship of cardiovascular complications with level of consciousness in patients with acute carbamazepine intoxication.
Medicinski arhiv 20120101
-
Carbamazepine-induced hepato-splenomegaly with erythematous rashes in a child.
Indian journal of pharmacology 20120101
-
Development and validation of quantitative structure-activity relationship models for compounds acting on serotoninergic receptors.
TheScientificWorldJournal 20120101
-
Delta-like ligand 4-notch blockade and tumor radiation response.
Journal of the National Cancer Institute 20111207
-
[New antiepileptic drugs, and therapeutic considerations].
Ideggyogyaszati szemle 20110930
-
A chemical-genetic screen reveals a mechanism of resistance to PI3K inhibitors in cancer.
Nature chemical biology 20110925
-
DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo.
Cancer research 20110915
-
Notch signaling modulates MUC16 biosynthesis in an in vitro model of human corneal and conjunctival epithelial cell differentiation.
Investigative ophthalmology & visual science 20110701
-
Opipramol.
Acta crystallographica. Section E, Structure reports online 20110701
-
An efficient approach to azirino and pyrrolo-fused dibenzazepines. Conformations of substituted dibenzo[c,f]pyrrolo[1,2-a]azepines.
Organic & biomolecular chemistry 20110521
-
Effects of combination of notch inhibitor plus hedgehog inhibitor or Wnt inhibitor on growth of leukemia cells.
Anticancer research 20110301
-
Presence and ex vivo formation of acridone in blood of patients routinely treated with carbamazepine: exploration of the 9-acridinecarboxaldehyde pathway.
Xenobiotica; the fate of foreign compounds in biological systems 20110201
-
Effects of carbamazepine and metabolites on IL-2, IL-5, IL-6, IL-10 and IFN-γ secretion in epileptic patients: the influence of co-medication.
Pharmacological reports : PR 20110101
-
Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.
PloS one 20110101
-
Synthesis and antiulcer activity evaluation of conjugates of amino acids with N-aroyl- N, N'-dicyclohexyl urea.
Chemistry Central journal 20110101
-
Therapeutic targeting of cancer stem cells.
Frontiers in oncology 20110101
-
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Bioorganic & medicinal chemistry letters 20101101
-
Early-stage blocking of Notch signaling inhibits the depletion of goblet cells in dextran sodium sulfate-induced colitis in mice.
Journal of gastroenterology 20100601
-
Intestinal stem cells lacking the Math1 tumour suppressor are refractory to Notch inhibitors.
Nature communications 20100517
-
Preparation and physicochemical characterization of a novel water-soluble prodrug of carbamazepine.
Journal of pharmaceutical sciences 20100401
-
Trimipraminium maleate.
Acta crystallographica. Section E, Structure reports online 20100201
-
Synthesis and antioxidant properties of some novel 5H-dibenz[b,f]azepine derivatives in different in vitro model systems.
European journal of medicinal chemistry 20100101
-
Conversion of metaplastic Barrett's epithelium into post-mitotic goblet cells by gamma-secretase inhibition.
Disease models & mechanisms 20100101
-
Role of eslicarbazepine in the treatment of epilepsy in adult patients with partial-onset seizures.
Therapeutics and clinical risk management 20100101
-
Determination of carbamazepine and its impurities iminostilbene and iminodibenzyl in solid dosage form by column high-performance liquid chromatography.
Journal of AOAC International 20100101
-
Gene expression profile analysis of genes in rat hippocampus from antidepressant treated rats using DNA microarray.
BMC neuroscience 20100101
-
Studies of Antimicrobial Activities of some 4-Thiazolidinone Fused Pyrimidines, [1,5]-Benzodiazepines and their Oxygen Substituted Hydroxylamine Derivatives.
Indian journal of pharmaceutical sciences 20100101
-
Rational design and synthesis of potent dibenzazepine motifs as beta-secretase inhibitors.
Journal of medicinal chemistry 20091022
-
Fate of carbamazepine during water treatment.
Environmental science & technology 20090815
-
Novel imine antioxidants at low nanomolar concentrations protect dopaminergic cells from oxidative neurotoxicity.
Journal of neurochemistry 20090701
-
Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening.
PLoS neglected tropical diseases 20090701
-
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche.
Nature medicine 20090601
-
Presence and fate of carbamazepine, oxcarbazepine, and seven of their metabolites at wastewater treatment plants.
Archives of environmental contamination and toxicology 20090401
-
Notch inhibits expression of the Krüppel-like factor 4 tumor suppressor in the intestinal epithelium.
Molecular cancer research : MCR 20081201
-
Thermal ring contraction of dibenz[b,f]azepin-5-yl radicals: new routes to pyrrolo[3,2,1-jk]carbazoles.
The Journal of organic chemistry 20080905
-
Cytenamide-formic acid (1/1).
Acta crystallographica. Section E, Structure reports online 20080801
-
Cytenamide trifluoro-acetic acid solvate.
Acta crystallographica. Section E, Structure reports online 20080701
-
Cytenamide-butyric acid (1/1).
Acta crystallographica. Section E, Structure reports online 20080701
-
Cytenamide-1,4-dioxane (2/1).
Acta crystallographica. Section E, Structure reports online 20080701
-
Cytenamide acetic acid solvate.
Acta crystallographica. Section E, Structure reports online 20080601
-
The Notch pathway in podocytes plays a role in the development of glomerular disease.
Nature medicine 20080301
-
Notch signaling is required for exocrine regeneration after acute pancreatitis.
Gastroenterology 20080201
-
Spectrophotometric determination of etodolac in pure form and pharmaceutical formulations.
Chemistry Central journal 20080101
-
[Immunochemical properties of conjugated antigens from N-substituted phenothiazines and dibenzazepines with antiarrhythmic activity].
Prikladnaia biokhimiia i mikrobiologiia 20080101
-
Gamma-secretase inhibition combined with platinum compounds enhances cell death in a large subset of colorectal cancer cells.
Cell communication and signaling : CCS 20080101
-
Modifications of antiepileptic drugs for improved tolerability and efficacy.
Perspectives in medicinal chemistry 20080101
-
Design, synthesis and biological evaluation of new oligopyrrole carboxamides linked with tricyclic DNA-intercalators as potential DNA ligands or topoisomerase inhibitors.
European journal of medicinal chemistry 20070601
-
Free-radical-scavenging effect of carbazole derivatives on AAPH-induced hemolysis of human erythrocytes.
Bioorganic & medicinal chemistry 20070301
-
Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design.
Drug target insights 20070101
-
The role of serendipity in drug discovery.
Dialogues in clinical neuroscience 20060901
-
Activation of T cells by carbamazepine and carbamazepine metabolites.
The Journal of allergy and clinical immunology 20060701
-
Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
-
Liquid chromatography-electrospray mass spectrometry determination of carbamazepine, oxcarbazepine and eight of their metabolites in human plasma.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051215
-
Intravenous immunoglobulin for treatment of toxic epidermal necrolysis.
The American journal of the medical sciences 20050201
-
2,2'-Bipyridine as a new and sensitive spectrophotometric reagent for the determination of nanoamounts of certain dibenzazepine class of tricyclic antidepressant drugs.
Farmaco (Societa chimica italiana : 1989) 20050101
-
Neurotoxicity induced by antiepileptic drugs in cultured hippocampal neurons: a comparative study between carbamazepine, oxcarbazepine, and two new putative antiepileptic drugs, BIA 2-024 and BIA 2-093.
Epilepsia 20041201
-
Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation.
Toxicological sciences : an official journal of the Society of Toxicology 20041101
-
Synthesis of medium ring heterocycles using an intramolecular Heck reaction.
Organic letters 20040819
-
Homoheteroaromaticity: the case study of azepine and dibenzazepine.
Organic & biomolecular chemistry 20040607
-
Substituent-dependent reactivity in the photodimerization of N-substituted dibenz[b,f]azepines.
Chemistry (Weinheim an der Bergstrasse, Germany) 20040105
-
Glutathione S-transferase pi as a target for tricyclic antidepressants in human brain.
Acta biochimica Polonica 20040101
-
Functionally distinct dopamine and octopamine transporters in the CNS of the cabbage looper moth.
European journal of biochemistry 20030201
-
Design, synthesis, and evaluation of new chemosensitizers in multi-drug-resistant Plasmodium falciparum.
Journal of medicinal chemistry 20020620
-
Putative identification of functional interactions between DNA intercalating agents and topoisomerase II using the V79 in vitro micronucleus assay.
Mutation research 20020619
-
Structure-based enzyme inhibitor design: modeling studies and crystal structure analysis of Pneumocystis carinii dihydrofolate reductase ternary complex with PT653 and NADPH.
Acta crystallographica. Section D, Biological crystallography 20020601
-
[Tricyclic antidepressants as inhibitors of brain glutathione-S-transferase].
Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20011201
-
Protective activity of aromatic amines and imines against oxidative nerve cell death.
Biological chemistry 20011101
-
Hexamethonium-type allosteric modulators of the muscarinic receptors bearing lateral dibenzazepine moieties.
Archiv der Pharmazie 20010401
-
Interactions between carbamazepine and polyethylene glycol (PEG) 6000: characterisations of the physical, solid dispersed and eutectic mixtures.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010201
