26054-60-4 | N-Carbobenzoxy-L-serine beta-lactone

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$41.00	$29.00
1g	97%	in stock	$86.00	$60.00
5g	97%	in stock	$246.00	$172.00
10g	97%	in stock	$452.00	$317.00
25g	97%	in stock	$1,105.00	$773.00
100g	97%	in stock	$3,869.00	$2,708.00

Description

• Catalog Number: AB28793
• Chemical Name: N-Carbobenzoxy-L-serine beta-lactone
• CAS Number: 26054-60-4
• Molecular Formula: C11H11NO4
• Molecular Weight: 221.2093
• MDL Number: MFCD02684302
• SMILES: O=C(N[C@H]1COC1=O)OCc1ccccc1

Computed Properties

• Complexity: 273
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 16
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 4
• XLogP3: 1.2

Literature

• Assay and inhibition of diacylglycerol lipase activity.

  Bioorganic & medicinal chemistry letters 20120715

• N-(2-oxo-3-oxetanyl)carbamic acid esters as N-acylethanolamine acid amidase inhibitors: synthesis and structure-activity and structure-property relationships.

  Journal of medicinal chemistry 20120524

• Synthesis and structure-activity relationships of N-(2-oxo-3-oxetanyl)amides as N-acylethanolamine-hydrolyzing acid amidase inhibitors.

  Journal of medicinal chemistry 20100812

• Dual modes of modification of hepatitis A virus 3C protease by a serine-derived beta-lactone: selective crystallization and formation of a functional catalytic triad in the active site.

  Journal of molecular biology 20051209

• Serine and threonine beta-lactones: a new class of hepatitis A virus 3C cysteine proteinase inhibitors.

  The Journal of organic chemistry 20020308

• Beta-lactones as a new class of cysteine proteinase inhibitors: inhibition of hepatitis A virus 3C proteinase by N-Cbz-serine beta-lactone.

  Organic letters 19990909