26159-34-2 | sodium (2S)-2-(6-methoxynaphthalen-2-yl)propanoate

Packsize	Purity	Availability	Price	Discounted Price
1g	99%	in stock	$8.00	$5.00
5g	99%	in stock	$10.00	$7.00
25g	99%	in stock	$25.00	$17.00
100g	99%	in stock	$76.00	$53.00
500g	99%	in stock	$299.00	$209.00

Description

• Catalog Number: AI46064
• Chemical Name: sodium (2S)-2-(6-methoxynaphthalen-2-yl)propanoate
• CAS Number: 26159-34-2
• Molecular Formula: C14H13NaO3
• Molecular Weight: 252.24098999999998
• MDL Number: MFCD00058507
• SMILES: COc1ccc2c(c1)ccc(c2)[C@@H](C(=O)[O-])C.[Na+]

Computed Properties

• Complexity: 282
• Covalently-Bonded Unit Count: 2
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 18
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3

Literature

• ATB-346, a novel hydrogen sulfide-releasing anti-inflammatory drug, induces apoptosis of human melanoma cells and inhibits melanoma development in vivo.

  Pharmacological research 20161201

• Hydrogen sulfide releasing naproxen offers better anti-inflammatory and chondroprotective effect relative to naproxen in a rat model of zymosan induced arthritis.

  European review for medical and pharmacological sciences 20150401

• Naproxcinod shows significant advantages over naproxen in the mdx model of Duchenne Muscular Dystrophy.

  Orphanet journal of rare diseases 20150101

• Effects of conventional and hydrogen sulfide-releasing non-steroidal anti-inflammatory drugs in rats with stress-induced and epinephrine-induced gastric damage.

  Stress (Amsterdam, Netherlands) 20141201

• Precision cut intestinal slices are an appropriate ex vivo model to study NSAID-induced intestinal toxicity in rats.

  Toxicology in vitro : an international journal published in association with BIBRA 20141001

• Enhanced chemopreventive effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer.

  Nitric oxide : biology and chemistry 20140915

• Naproxen and cromolyn as new glycogen synthase kinase 3β inhibitors for amelioration of diabetes and obesity: an investigation by docking simulation and subsequent in vitro/in vivo biochemical evaluation.

  Journal of biochemical and molecular toxicology 20130901

• TRPV1 antagonistic analgesic effect: a randomized study of AZD1386 in pain after third molar extraction.

  Pain 20130601

• (S)-Naproxen as a platform to develop chiral derivatizing reagent for reversed-phase high-performance liquid chromatographic enantioseparation of analytes having a carbonyl functional group.

  Biomedical chromatography : BMC 20121201

• Relating hydrogen-bonding interactions with the phase behavior of naproxen/PVP K 25 solid dispersions: evaluation of solution-cast and quench-cooled films.

  Molecular pharmaceutics 20121105

• Nonlinear optical imaging for sensitive detection of crystals in bulk amorphous powders.

  Journal of pharmaceutical sciences 20121101

• Determination of non-steroidal anti-inflammatory drugs in urine by hollow-fiber liquid membrane-protected solid-phase microextraction based on sol-gel fiber coating.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121101

• Single-pass intestinal perfusion to establish the intestinal permeability of model drugs in mouse.

  International journal of pharmaceutics 20121015

• The role of microbial adaptation and biodegradable dissolved organic carbon on the attenuation of trace organic chemicals during groundwater recharge.

  The Science of the total environment 20121015

• Plasma and cerebrospinal fluid pharmacokinetics of naproxen in children.

  Journal of clinical pharmacology 20121001

• Effects of non-steroidal antiinflammatory drugs on D-serine-induced oxidative stress in vitro.

  Drug and chemical toxicology 20121001

• An investigation of the adsorption of hydroxypropylmethyl cellulose 2910 5 mPa s and polyvinylpyrrolidone K90 around Naproxen nanocrystals.

  Journal of pharmaceutical sciences 20121001

• Nanostructured conducting molecularly imprinted polymer for selective uptake/release of naproxen by the electrochemically controlled sorbent.

  Analytical biochemistry 20120915

• Effects of naproxen on the hypobaric hypoxia-induced immune changes in male rats.

  European journal of applied physiology 20120901

• Physicochemical characterization and structural evaluation of a specific 2:1 cocrystal of naproxen-nicotinamide.

  Journal of pharmaceutical sciences 20120901

• Dissolution of weak acids under laminar flow and rotating disk hydrodynamic conditions: application of a comprehensive convection-diffusion-migration-reaction transport model.

  Journal of pharmaceutical sciences 20120901

• Reduced ulcerogenic potential and antiarthritic effect of chitosan-naproxen sodium complexes.

  AAPS PharmSciTech 20120901

• An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee.

  Pain 20120901

• Reversible renal glycosuria in acute interstitial nephritis.

  The American journal of the medical sciences 20120901

• Pre-concentration of non-steroidal anti-inflammatory drugs in water using dispersive liquid-liquid and single-drop microextraction with high-performance liquid chromatography.

  Journal of separation science 20120901

• Efficacy, end points and eventualities: sumatriptan/naproxen versus butalbital/paracetamol/caffeine in the treatment of migraine.

  Expert review of clinical pharmacology 20120901

• Rejection of pharmaceuticals by forward osmosis membranes.

  Journal of hazardous materials 20120815

• Is the amorphous fraction of a dried nanosuspension caused by milling or by drying? A case study with Naproxen and Cinnarizine.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120801

• Bioavailability of pharmaceuticals in waters close to wastewater treatment plants: use of fish bile for exposure assessment.

  Environmental toxicology and chemistry 20120801

• Sodium-23 solid-state nuclear magnetic resonance of commercial sodium naproxen and its solvates.

  Journal of pharmaceutical sciences 20120801

• Copper(II) coordination properties of the integrin ligand sequence PHSRN and its new β-cyclodextrin conjugates.

  Journal of inorganic biochemistry 20120801

• Challenges in the simultaneous quantitation of sumatriptan and naproxen in human plasma: application to a bioequivalence study.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120801

• Naproxen-induced ST-elevation myocardial infarction in a 33-year-old man.

  Journal of cardiovascular medicine (Hagerstown, Md.) 20120701

• Insight into NSAID-induced membrane alterations, pathogenesis and therapeutics: characterization of interaction of NSAIDs with phosphatidylcholine.

  Biochimica et biophysica acta 20120701

• Determination of non-steroidal anti-inflammatory drugs in urine by the combination of stir membrane liquid-liquid-liquid microextraction and liquid chromatography.

  Analytical and bioanalytical chemistry 20120701

• Naproxcinod.

  Prescrire international 20120701

• Differential contribution of Igepal and CnTAB micelles on the photophysics of nonsteroidal drug Naproxen.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120615

• Celecoxib or naproxen treatment does not benefit depressive symptoms in persons age 70 and older: findings from a randomized controlled trial.

  The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20120601

• pH sensitive silica nanotubes as rationally designed vehicles for NSAIDs delivery.

  Colloids and surfaces. B, Biointerfaces 20120601

• Intramuscular ketorolac inhibits activation of rat peripheral NMDA receptors.

  Journal of neurophysiology 20120601

• Novel brain targeting prodrugs of naproxen based on dimethylamino group with various linkages.

  Arzneimittel-Forschung 20120601

• Responsiveness of the OARSI-OMERACT osteoarthritis pain and function measures.

  Osteoarthritis and cartilage 20120601

• Sorption and desorption of carbamazepine, naproxen and triclosan in a soil irrigated with raw wastewater: estimation of the sorption parameters by considering the initial mass of the compounds in the soil.

  Chemosphere 20120601

• Prevention of pegfilgrastim-induced bone pain: a phase III double-blind placebo-controlled randomized clinical trial of the university of rochester cancer center clinical community oncology program research base.

  Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120601

• Randomized trial of sumatriptan and naproxen sodium combination in adolescent migraine.

  Pediatrics 20120601

• Triplet excimers of fluoroquinolones in aqueous media.

  The journal of physical chemistry. A 20120531

• Low crosslinking imprinted coatings based on liquid crystal for capillary electrochromatography.

  Journal of chromatography. A 20120511

• The inhibitory action of the antimigraine nonsteroidal anti-inflammatory drug naproxen on P2X3 receptor-mediated responses in rat trigeminal neurons.

  Neuroscience 20120503

• Correlations between electrochemical behaviors and DNA photooxidative properties of non-steroïdal anti-inflammatory drugs and their photoproducts.

  Journal of photochemistry and photobiology. B, Biology 20120502

• Pharmacokinetics and relative bioavailability of a fixed-dose combination of enteric-coated naproxen and non-enteric-coated esomeprazole magnesium.

  Journal of clinical pharmacology 20120501

• Silver nanoparticle-enhanced chemiluminescence method for determining naproxen based on europium(III)-sensitized Ce(IV)-Na2S2O4 reaction.

  Journal of fluorescence 20120501

• Can compression induce demixing in amorphous solid dispersions? A case study of naproxen-PVP K25.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120501

• Risk assessment of premature drug release during wet granulation of ordered mesoporous silica loaded with poorly soluble compounds itraconazole, fenofibrate, naproxen, and ibuprofen.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120501

• Prevention of bleomycin-induced lung fibrosis in mice by a novel approach of parallel inhibition of cyclooxygenase and nitric-oxide donation using NCX 466, a prototype cyclooxygenase inhibitor and nitric-oxide donor.

  The Journal of pharmacology and experimental therapeutics 20120501

• A fluorescent chiral chemosensor for the recognition of the two enantiomers of chiral carboxylates.

  Chirality 20120501

• Calf thymus DNA binding studies of the new neodymium-naproxen complex.

  Journal of biochemical and molecular toxicology 20120501

• Thermo-sensitive chitosan based semi-IPN hydrogels for high loading and sustained release of anionic drugs.

  International journal of biological macromolecules 20120501

• Preparation of high solubilizable microemulsion of naproxen and its solubilization mechanism.

  International journal of pharmaceutics 20120415

• Effects of non-steroidal anti-inflammatory drug treatments on cognitive decline vary by phase of pre-clinical Alzheimer disease: findings from the randomized controlled Alzheimer's Disease Anti-inflammatory Prevention Trial.

  International journal of geriatric psychiatry 20120401

• Efficacy of transcutaneous electrical nerve stimulation for pain relief in women undergoing office endometrial biopsy.

  Archives of gynecology and obstetrics 20120401

• Sumatriptan-naproxen and butalbital: a double-blind, placebo-controlled crossover study.

  Headache 20120401

• Biofilm controlled sorption of selected acidic drugs on river sediments characterized by different organic carbon content.

  Chemosphere 20120401

• Pharmacological synergy: the next frontier on therapeutic advancement for migraine.

  Headache 20120401

• Enhancement of the activity and enantioselectivity of lipase by sol-gel encapsulation immobilization onto β-cyclodextrin-based polymer.

  Applied biochemistry and biotechnology 20120401

• The effect of non-steroidal anti-inflammatory drugs on the endothelial function of patients with osteoarthritis in short term.

  International journal of rheumatic diseases 20120401

• Adsorptive removal of naproxen and clofibric acid from water using metal-organic frameworks.

  Journal of hazardous materials 20120330

• Determination of non-steroidal anti-inflammatory drugs in water samples by solid-phase microextraction based sol-gel technique using poly(ethylene glycol) grafted multi-walled carbon nanotubes coated fiber.

  Analytica chimica acta 20120330

• Liposomes self-assembled from electrosprayed composite microparticles.

  Nanotechnology 20120316

• Hydrogen sulfide-releasing NSAIDs inhibit the growth of human cancer cells: a general property and evidence of a tissue type-independent effect.

  Biochemical pharmacology 20120315

• A double-blind controlled trial of a single dose naproxen and an amino acid medical food theramine for the treatment of low back pain.

  American journal of therapeutics 20120301

• Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs.

  Toxicology in vitro : an international journal published in association with BIBRA 20120301

• Emerging pollutants in sewage, surface and drinking water in Galicia (NW Spain).

  Chemosphere 20120301

• Gastrointestinal bleeding and possible hypothyroidism.

  The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20120301

• Pharmacokinetic and ulcerogenic studies of naproxen prodrugs designed for specific brain delivery.

  Archives of pharmacal research 20120301

• Preparation and characterization of hydroxypropyl methyl cellulose films containing stable BCS Class II drug nanoparticles for pharmaceutical applications.

  International journal of pharmaceutics 20120227

• In vitro release from oil injectables for intra-articular administration: Importance of interfacial area, diffusivity and partitioning.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120214

• Probing influence of mesophasic transformation on performance of self-emulsifying system: effect of ion.

  Molecular pharmaceutics 20120206

• Nonsteroidal anti-inflammatory drugs-induced generalized fixed drug eruption: two cases.

  Human & experimental toxicology 20120201

• Biotransformation of three pharmaceutical active compounds by the fungus Phanerochaete chrysosporium in a fed batch stirred reactor under air and oxygen supply.

  Biodegradation 20120201

• Quantum chemistry study of molecular structure and vibrational spectrum of naproxen.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20120201

• Naproxen or estradiol for bleeding and spotting with the levonorgestrel intrauterine system: a randomized controlled trial.

  American journal of obstetrics and gynecology 20120201

• An examination of the thermodynamics of fusion, vaporization, and sublimation of ibuprofen and naproxen by correlation gas chromatography.

  Journal of pharmaceutical sciences 20120201

• Carboxylesterases 1 and 2 hydrolyze phospho-nonsteroidal anti-inflammatory drugs: relevance to their pharmacological activity.

  The Journal of pharmacology and experimental therapeutics 20120201

• Biological evaluation of cobalt(II) complexes with non-steroidal anti-inflammatory drug naproxen.

  Journal of inorganic biochemistry 20120201

• Naproxen glycine conjugate-synthesis, pharmaceutical preformulation and pharmacodynamic evaluation.

  Drug delivery 20120201

• Effect of carboxylic acid on micelles of a neutral amphiphilic dendro-calix[4]arene.

  Organic & biomolecular chemistry 20120128

• A connection between the binding properties of imprinted and nonimprinted polymers: a change of perspective in molecular imprinting.

  Journal of the American Chemical Society 20120125

• Pain management for inflammatory arthritis (rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and other spondylarthritis) and gastrointestinal or liver comorbidity.

  The Cochrane database of systematic reviews 20120118

• Influence of solvent composition on the miscibility and physical stability of naproxen/PVP K 25 solid dispersions prepared by cosolvent spray-drying.

  Pharmaceutical research 20120101

• Sumatriptan-naproxen migraine efficacy in allodynic patients: early intervention.

  Headache 20120101

• Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial.

  International endodontic journal 20120101

• Effects of cyclooxygenase inhibition on cardiovascular function in a hypercholesterolemic swine model of chronic ischemia.

  American journal of physiology. Heart and circulatory physiology 20120101

• Identification of cytokines and signaling proteins differentially regulated by sumatriptan/naproxen.

  Headache 20120101

• Inflammatory and noninflammatory arthropathy in patients with 18q deletion syndrome.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20120101

• Kashin-Beck disease in Sichuan, China: report of a pilot open therapeutic trial.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20120101

• Adult-onset Still's disease in an 83-year-old.

  Journal of the American Geriatrics Society 20120101

• Novel multi-biotin grafted poly(lactic acid) and its self-assembling nanoparticles capable of binding to streptavidin.

  International journal of nanomedicine 20120101

• Gastrointestinal-sparing effects of novel NSAIDs in rats with compromised mucosal defence.

  PloS one 20120101

• A fatal case of cutaneous adverse drug-induced toxic epidermal necrolysis associated with severe rhabdomyolysis.

  Annals of Saudi medicine 20120101

• Pharmacological differences of endothelin receptors-mediated modulation in cultured interstitial cells of Cajal from the murine small and large intestine.

  Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101

• Comparison of the analgesic effects of oral tramadol and naproxen sodium on pain relief during IUD insertion.

  Journal of minimally invasive gynecology 20120101

• Crystal structures of three classes of non-steroidal anti-inflammatory drugs in complex with aldo-keto reductase 1C3.

  PloS one 20120101

• Efficacy and tolerability of celecoxib versus naproxen in patients with osteoarthritis of the knee: a randomized, double-blind, double-dummy trial.

  The Journal of international medical research 20120101

• [Development of novel methods for preparing chiral non-steroidal anti-inflammatory drugs (NSAIDs) by asymmetric esterification].

  Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20120101

• Effect of feeding strategies on pharmaceutical removal by subsurface flow constructed wetlands.

  Journal of environmental quality 20120101

• Degradation of naproxen by combination of Fenton reagent and ultrasound irradiation: optimization using response surface methodology.

  Water science and technology : a journal of the International Association on Water Pollution Research 20120101

• High density micromass cultures of a human chondrocyte cell line: a reliable assay system to reveal the modulatory functions of pharmacological agents.

  Biochemical pharmacology 20111215

• A high-throughput spectrophotometric approach for evaluation of precipitation resistance.

  Journal of pharmaceutical and biomedical analysis 20111205

• Therapeutic and cytotoxic effects of the novel antipsoriasis codrug, naproxyl-dithranol, on HaCaT cells.

  Molecular pharmaceutics 20111205

• Unusual chromatographic enantioseparation behavior of naproxen on an immobilized polysaccharide-based chiral stationary phase.

  Journal of chromatography. A 20111202

• Effect of anthocyanins on expression of matrix metalloproteinase-2 in naproxen-induced gastric ulcers.

  The British journal of nutrition 20111201

• A fixed-dose combination of naproxen and esomeprazole magnesium has comparable upper gastrointestinal tolerability to celecoxib in patients with osteoarthritis of the knee: results from two randomized, parallel-group, placebo-controlled trials.

  Annals of medicine 20111201

• Stereoselective inhibitory effect of flurbiprofen, ibuprofen and naproxen on human organic anion transporters hOAT1 and hOAT3.

  Biopharmaceutics & drug disposition 20111201

• Impact of a fixed-dose combination of naproxen and esomeprazole magnesium on serum thromboxane B2 inhibition by low-dose aspirin over 5 days in healthy adults: a phase I, randomized, double-blind, placebo-controlled, noninferiority trial.

  Clinical therapeutics 20111201

• Photosensitivity induced by naproxen.

  Photodermatology, photoimmunology & photomedicine 20111201

• Evaluation of the migraine treatment sumatriptan/naproxen sodium on blood pressure following long-term administration.

  Journal of clinical hypertension (Greenwich, Conn.) 20111201

• A microfluidic platform for pharmaceutical salt screening.

  Lab on a chip 20111121

• Enantiospecific fate of ibuprofen, ketoprofen and naproxen in a laboratory-scale membrane bioreactor.

  Water research 20111115

• Naproxen-induced fixed drug eruption: a case report.

  Human & experimental toxicology 20111101

• Chemiluminescence of the reaction system Ce(IV)-non-steroidal anti-inflammatory drugs containing europium(III) ions and its application to the determination of naproxen in pharmaceutical preparations and urine.

  Journal of fluorescence 20111101

• Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats.

  Cancer prevention research (Philadelphia, Pa.) 20111101

• Characterization and relative response factor determination of process related impurity in Naproxen by nuclear magnetic resonance spectroscopy.

  Journal of pharmaceutical and biomedical analysis 20111101

• Risk of ST versus non-ST elevation myocardial infarction associated with non-steroidal anti-inflammatory drugs.

  Heart (British Cardiac Society) 20111101

• Bromination of selected pharmaceuticals in water matrices.

  Chemosphere 20111101

• Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish.

  Chemosphere 20111101

• Bead layering as a process to stabilize nanosuspensions: influence of drug hydrophobicity on nanocrystal reagglomeration following in-vitro release from sugar beads.

  The Journal of pharmacy and pharmacology 20111101

• Naproxen as prophylaxis against atrial fibrillation after cardiac surgery: the NAFARM randomized trial.

  The American journal of medicine 20111101

• Pre-cut dried blood spot (PCDBS): an alternative to dried blood spot (DBS) technique to overcome hematocrit impact.

  Rapid communications in mass spectrometry : RCM 20111015

• An enantioselective, intermolecular α-arylation of ester enolates to form tertiary stereocenters.

  Journal of the American Chemical Society 20111012

• Coamorphous drug systems: enhanced physical stability and dissolution rate of indomethacin and naproxen.

  Molecular pharmaceutics 20111003

• Tailor-made release triggering from hot-melt extruded complexes of basic polyelectrolyte and poorly water-soluble drugs.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20111001

• Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis.

  Gastroenterology 20111001

• Long-term evaluation of sumatriptan and naproxen sodium for the acute treatment of migraine in adolescents.

  Headache 20111001

• Quiz Page October 2011: An under-recognized cause of CKD.

  American journal of kidney diseases : the official journal of the National Kidney Foundation 20111001

• Naproxen-induced liver injury.

  Hepatobiliary & pancreatic diseases international : HBPD INT 20111001

• Evaluation of the use of sumatriptan-naproxen sodium for menstrual migraine and dysmenorrhea.

  Expert review of neurotherapeutics 20111001

• Coatings of one monomer molecularly imprinted polymers for open tubular capillary electrochromatography.

  Journal of chromatography. A 20110916

• Evaluation of skin permeation and anti-inflammatory and analgesic effects of new naproxen microemulsion formulations.

  International journal of pharmaceutics 20110915

• [F-18]FDDNP microPET imaging correlates with brain Aβ burden in a transgenic rat model of Alzheimer disease: effects of aging, in vivo blockade, and anti-Aβ antibody treatment.

  Neurobiology of disease 20110901

• Design, synthesis and biological evaluation of brain-specific glucosyl thiamine disulfide prodrugs of naproxen.

  European journal of medicinal chemistry 20110901

• High-fat diet alters prostanoid balance and perfusion in ischemic myocardium of naproxen-treated swine.

  Surgery 20110901

• Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies.

  PLoS medicine 20110901

• BTK gene mutation in two non-identical twins with X-linked agammaglobulinemia associated with polyarticular juvenile idiopathic arthritis.

  The Israel Medical Association journal : IMAJ 20110901

• Interaction of naproxen amphiphilic derivatives with biomembrane models evaluated by differential scanning calorimetry and Langmuir-Blodgett studies.

  Journal of colloid and interface science 20110815

• Enantiomeric separation of (R, S)-naproxen by recycling high speed counter-current chromatography with hydroxypropyl-β-cyclodextrin as chiral selector.

  Journal of chromatography. A 20110812

• Microbial transformation of pharmaceuticals naproxen, bisoprolol, and diclofenac in aerobic and anaerobic environments.

  Archives of environmental contamination and toxicology 20110801

• Risk factors predictive of joint replacement in a 2-year multicentre clinical trial in knee osteoarthritis using MRI: results from over 6 years of observation.

  Annals of the rheumatic diseases 20110801

• Mast cells drive mesenteric afferent signalling during acute intestinal ischaemia.

  The Journal of physiology 20110801

• A practical approach to reduce interference due to in-source collision-induced dissociation of acylglucuronides in LC-MS/MS.

  Bioanalysis 20110801

• Enantioselective analysis of ibuprofen, ketoprofen and naproxen in wastewater and environmental water samples.

  Journal of chromatography. A 20110722

• Erythema nodosum induced by kerion celsi of the scalp in a woman.

  Mycoses 20110701

• Pharmacokinetic-pharmacodynamic modeling of the inhibitory effects of naproxen on the time-courses of inflammatory pain, fever, and the ex vivo synthesis of TXB2 and PGE2 in rats.

  Pharmaceutical research 20110701

• Harmful effects of NSAIDs among patients with hypertension and coronary artery disease.

  The American journal of medicine 20110701

• Extended results of the Alzheimer's disease anti-inflammatory prevention trial.

  Alzheimer's & dementia : the journal of the Alzheimer's Association 20110701

• Synthesis of (S)-naproxen-benzotriazole and its application as chiral derivatizing reagent for microwave-assisted synthesis and indirect high performance liquid chromatographic separation of diastereomers of penicillamine, cysteine and homocysteine.

  Journal of chromatography. A 20110610

• Detection of naproxen and its metabolites in fish bile following intraperitoneal and aqueous exposure.

  Environmental science and pollution research international 20110601

• Modelling of pain intensity and informative dropout in a dental pain model after naproxcinod, naproxen and placebo administration.

  British journal of clinical pharmacology 20110601

• Uptake from water, biotransformation, and biliary excretion of pharmaceuticals by rainbow trout.

  Environmental toxicology and chemistry 20110601

• Fixed-dose combination of enteric-coated naproxen and immediate-release esomeprazole has comparable efficacy to celecoxib for knee osteoarthritis: two randomized trials.

  Current medical research and opinion 20110601

• An LC-MS/MS procedure for the quantification of naproxen in human plasma: development, validation, comparison with other methods, and application to a pharmacokinetic study.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110601

• Multi-center comparison of response to a single tablet of sumatriptan 85 mg and naproxen 500 mg vs usual therapy treating multiple migraine attacks as measured by the completeness of response survey.

  Headache 20110601

• An investigation of formulation factors affecting feasibility of alginate-chitosan microparticles for oral delivery of naproxen.

  Archives of pharmacal research 20110601

• [Low dosage acetylsalicylic acid plus naproxen--a small risk of interaction].

  Lakartidningen 20110601

• Duration of treatment with nonsteroidal anti-inflammatory drugs and impact on risk of death and recurrent myocardial infarction in patients with prior myocardial infarction: a nationwide cohort study.

  Circulation 20110524

• [Synergistic combination therapy in osteoporosis. Strategies against painful bone loss].

  MMW Fortschritte der Medizin 20110512

• Naproxen test for neoplastic fever may reduce suffering.

  Journal of palliative medicine 20110501

• Effects of naproxcinod on blood pressure in patients with osteoarthritis.

  The American journal of cardiology 20110501

• Quality-by-design: an integrated process analytical technology approach to determine the nucleation and growth mechanisms during a dynamic pharmaceutical coprecipitation process.

  Journal of pharmaceutical sciences 20110501

• Oral naproxen versus oral tramadol for analgesia after cesarean delivery.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20110501

• Sumatriptan-naproxen sodium for menstrual migraine and dysmenorrhea: satisfaction, productivity, and functional disability outcomes.

  Headache 20110501

• Effects of selected pharmaceutically active compounds on treatment performance in sequencing batch reactors mimicking wastewater treatment plants operations.

  Water research 20110501

• Blood pressure effects of naproxcinod in hypertensive patients.

  Journal of clinical hypertension (Greenwich, Conn.) 20110501

• Fluorous derivatization and fluorous-phase separation for fluorometric determination of naproxen and felbinac in human plasma.

  Journal of pharmaceutical and biomedical analysis 20110428

• Naphthalene triplet excited state as a probe for the assessment of drug distribution in binary protein systems.

  The journal of physical chemistry. B 20110421

• Naproxen interferes with the assembly of Aβ oligomers implicated in Alzheimer's disease.

  Biophysical journal 20110420

• Palmar fasciitis with polyarthritis syndrome in a patient with breast cancer.

  Clinical rheumatology 20110401

• Sorption and degradation of wastewater-associated non-steroidal anti-inflammatory drugs and antibiotics in soils.

  Chemosphere 20110401

• Long-term safety of naproxen and esomeprazole magnesium fixed-dose combination: phase III study in patients at risk for NSAID-associated gastric ulcers.

  Current medical research and opinion 20110401

• [Spondylodiscitis caused by Streptococcus pneumonia associated with an infected abdominal aortic aneurysm].

  Enfermedades infecciosas y microbiologia clinica 20110401

• Separation of the two enantiomers of naproxcinod by chiral normal-phase liquid chromatography.

  Journal of chromatographic science 20110401

• Application of London-type dispersion corrections to the solid-state density functional theory simulation of the terahertz spectra of crystalline pharmaceuticals.

  Physical chemistry chemical physics : PCCP 20110314

• Ethanesulfohydroxamic acid ester prodrugs of nonsteroidal anti-inflammatory drugs (NSAIDs): synthesis, nitric oxide and nitroxyl release, cyclooxygenase inhibition, anti-inflammatory, and ulcerogenicity index studies.

  Journal of medicinal chemistry 20110310

• Indirect enantioresolution of (R,S)-mexiletine by reversed-phase high-performance liquid chromatography via diastereomerization with [(S,S)-O,O'-di-p-toluoyl tartaric acid anhydride], (S)-naproxen and nine chiral reagents synthesized as variants of Marfey's reagent.

  Biomedical chromatography : BMC 20110301

• Development of a polymeric patch impregnated with naproxen as a model of transdermal sustained release system.

  Journal of pharmaceutical sciences 20110301

• Interaction of copper(II) with the non-steroidal anti-inflammatory drugs naproxen and diclofenac: synthesis, structure, DNA- and albumin-binding.

  Journal of inorganic biochemistry 20110301

• Naproxen-eudragit RS100 nanoparticles: preparation and physicochemical characterization.

  Colloids and surfaces. B, Biointerfaces 20110301

• Improvement of catalytic activity of lipase from Candida rugosa via sol-gel encapsulation in the presence of calix(aza)crown.

  Bioresource technology 20110301

• Naproxen/esomeprazole fixed-dose combination: for the treatment of arthritic symptoms and to reduce the risk of gastric ulcers.

  Drugs & aging 20110301

• Low-dose naproxen interferes with the antiplatelet effects of aspirin in healthy subjects: recommendations to minimize the functional consequences.

  Arthritis and rheumatism 20110301

• Quality-by-Design (QbD): An integrated process analytical technology (PAT) approach for a dynamic pharmaceutical co-precipitation process characterization and process design space development.

  International journal of pharmaceutics 20110227

• Preparation, in vitro characterization and in vivo release of naproxen loaded in poly-caprolactone nanoparticles.

  Pharmaceutical development and technology 20110201

• Folate-targeted drug-delivery systems prepared by nano-comminution.

  Drug development and industrial pharmacy 20110201

• Efficacy and safety of naproxcinod in patients with osteoarthritis of the knee: a 53-week prospective randomized multicenter study.

  Seminars in arthritis and rheumatism 20110201

• Efficacy and safety of Derris scandens Benth extracts in patients with knee osteoarthritis.

  Journal of alternative and complementary medicine (New York, N.Y.) 20110201

• Coaxial electrospinning with organic solvent for controlling the size of self-assembled nanoparticles.

  Chemical communications (Cambridge, England) 20110128

• ¹H NMR-based metabolic profiling of naproxen-induced toxicity in rats.

  Toxicology letters 20110115

• Synthesis of hollow CaCO3 nanospheres templated by micelles of poly(styrene-b-acrylic acid-b-ethylene glycol) in aqueous solutions.

  Langmuir : the ACS journal of surfaces and colloids 20110104

• Polymer-conjugated albumin and fibrinogen composite hydrogels as cell scaffolds designed for affinity-based drug delivery.

  Acta biomaterialia 20110101

• Structural evaluation of crystalline ternary γ-cyclodextrin complex.

  Journal of pharmaceutical sciences 20110101

• Immobilization of Candida rugosa lipase on glass beads for enantioselective hydrolysis of racemic naproxen methyl ester.

  Bioresource technology 20110101

• Demographic, medical, and behavioral characteristics associated with over the counter non-steroidal anti-inflammatory drug use in a population-based cohort: results from the Multi-Ethnic Study of Atherosclerosis.

  Pharmacoepidemiology and drug safety 20110101

• Effects of analgesics on orthodontic pain.

  American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics 20110101

• Effects of naproxen and sulphasalazine or methotrexate on hypothalamic-pituitary-adrenal axis activity in patients with rheumatoid arthritis.

  Clinical and experimental rheumatology 20110101

• [Clostridium difficile-associated diarrhea: causes and relationship to reactive arthritis].

  Harefuah 20110101

• Fixed drug eruption due to nabumetone in a patient with previous fixed drug eruptions due to naproxen.

  Journal of investigational allergology & clinical immunology 20110101

• Crystal forms of naproxen.

  Archives of pharmacal research 20110101

• [Cyclooxygenases inhibitors and other compounds with antiinflammatory potential in osteoarthrosis--part II].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20110101

• Longitudinal numbers-needed-to-treat (NNT) for achieving various levels of analgesic response and improvement with etoricoxib, naproxen, and placebo in ankylosing spondylitis.

  BMC musculoskeletal disorders 20110101

• Novel PEG-graft-PLA nanoparticles with the potential for encapsulation and controlled release of hydrophobic and hydrophilic medications in aqueous medium.

  International journal of nanomedicine 20110101

• NSAID-sensitive antihistamine-induced urticaria/angioedema.

  Journal of investigational allergology & clinical immunology 20110101

• [Fever of unknown origin and digestive hemorrhage].

  Medicina 20110101

• Synergistic effect of the interaction between naproxen and citral on inflammation in rats.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20101215

• NO-releasing NSAIDs suppress NF-κB signaling in vitro and in vivo through S-nitrosylation.

  Cancer letters 20101208

• Decrease in serum level of matrix metalloproteinases is predictive of the disease-modifying effect of osteoarthritis drugs assessed by quantitative MRI in patients with knee osteoarthritis.

  Annals of the rheumatic diseases 20101201

• Relationship between bone marrow lesions, cartilage loss and pain in knee osteoarthritis: results from a randomised controlled clinical trial using MRI.

  Annals of the rheumatic diseases 20101201

• Preparation and physicochemical characterization of naproxen-PLGA nanoparticles.

  Colloids and surfaces. B, Biointerfaces 20101201

• Efficacy, safety, and effects on blood pressure of naproxcinod 750 mg twice daily compared with placebo and naproxen 500 mg twice daily in patients with osteoarthritis of the hip: a randomized, double-blind, parallel-group, multicenter study.

  Arthritis and rheumatism 20101201

• A novel controlled release drug delivery system for multiple drugs based on electrospun nanofibers containing nanoparticles.

  Journal of pharmaceutical sciences 20101201

• Topical delivery of a naproxen-dithranol co-drug: in vitro skin penetration, permeation, and staining.

  Pharmaceutical research 20101201

• Efficacy and safety of flavocoxid compared with naproxen in subjects with osteoarthritis of the knee- a subset analysis.

  Advances in therapy 20101201

• An enhanced bunionectomy model as a potential tool for early decision-making in the development of new analgesics.

  Advances in therapy 20101201

• Nonsteroidal anti-inflammatory drug naproxen destabilizes Aβ amyloid fibrils: a molecular dynamics investigation.

  The journal of physical chemistry. B 20101125

• Occurrence, temporal evolution and risk assessment of pharmaceutically active compounds in Doñana Park (Spain).

  Journal of hazardous materials 20101115

• Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen.

  The Journal of biological chemistry 20101105

• The adsorption of Naproxen enantiomers on the chiral stationary phase Whelk-O1 under reversed-phase conditions: the effect of buffer composition.

  Journal of chromatography. A 20101105

• Efficient production of (S)-naproxen with (R)-substrate recycling using an overexpressed carboxylesterase BsE-NP01.

  Applied biochemistry and biotechnology 20101101

• A quantitative evaluation of the regulatory assessment of the benefits and risks of rofecoxib relative to naproxen: an application of the incremental net-benefit framework.

  Pharmacoepidemiology and drug safety 20101101

• Clinical trial: endoscopic evaluation of naproxen etemesil, a naproxen prodrug, vs. naproxen - a proof-of-concept, randomized, double-blind, active-comparator study.

  Alimentary pharmacology & therapeutics 20101101

• Effects of selective cyclooxygenase-2 and nonselective cyclooxygenase inhibition on ischemic myocardium.

  The Journal of thoracic and cardiovascular surgery 20101101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Capacity of a horizontal subsurface flow constructed wetland system for the removal of emerging pollutants: an injection experiment.

  Chemosphere 20101101

• A primer on pain relief.

  Consumer reports 20101101

• Brain-specific delivery of naproxen using different carrier systems.

  Archiv der Pharmazie 20101101

• Persistent arthritis following Chikungunya virus infection.

  The New Zealand medical journal 20101015

• The effects of COX-2 inhibitor during osteogenic differentiation of bone marrow-derived human mesenchymal stem cells.

  Stem cells and development 20101001

• Binding of nonsteroidal anti-inflammatory drugs to Abeta fibril.

  Proteins 20101001

• Antibacterial and ulcer healing effects of organoselenium compounds in naproxen induced and Helicobacter pylori infected Wistar rat model.

  Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20101001

• Management of menstrual migraine: a review of current abortive and prophylactic therapies.

  Current pain and headache reports 20101001

• Determination of non-steroidal anti-inflammatory drugs in sewage sludge by direct hollow fiber supported liquid membrane extraction and liquid chromatography-mass spectrometry.

  Journal of chromatography. A 20101001

• Efficacy and safety of flavocoxid, a novel therapeutic, compared with naproxen: a randomized multicenter controlled trial in subjects with osteoarthritis of the knee.

  Advances in therapy 20101001

• Effect of cytochrome P450 and aldo-keto reductase inhibitors on progesterone inactivation in primary bovine hepatic cell cultures.

  Journal of dairy science 20101001

• Consistency of response to sumatriptan/naproxen sodium in a placebo-controlled cross-over study.

  Cephalalgia : an international journal of headache 20101001

• Development and validation of a RP-HPLC method for simultaneous estimation of naproxen and ranitidinehydrochloride.

  Pakistan journal of pharmaceutical sciences 20101001

• The combination of naproxen and citral reduces nociception and gastric damage in rats.

  Archives of pharmacal research 20101001

• Phase behavior of ketoprofen-poly(lactic acid) drug particles formed by rapid expansion of supercritical solutions.

  Langmuir : the ACS journal of surfaces and colloids 20100921

• Naproxen/esomeprazole (Vimovo).

  The Medical letter on drugs and therapeutics 20100920

• Effective polymeric dispersants for vacuum, convection and freeze drying of drug nanosuspensions.

  International journal of pharmaceutics 20100915

• Stereoselective interaction of epimeric naproxen-RGD peptides with human serum albumin.

  Biomacromolecules 20100913

• Primary dysmenorrhea among Mexican university students: prevalence, impact and treatment.

  European journal of obstetrics, gynecology, and reproductive biology 20100901

• Celecoxib, but not rofecoxib or naproxen, attenuates cardiac hypertrophy and fibrosis induced in vitro by angiotensin and aldosterone.

  Clinical and experimental pharmacology & physiology 20100901

• Copper (II) complexes of the anti-inflammatory drug naproxen and 3-pyridylmethanol as auxiliary ligand. Characterization, superoxide dismutase and catecholase--mimetic activities.

  European journal of medicinal chemistry 20100901

• Evaluation of glycofurol-based gel as a new vehicle for topical application of naproxen.

  AAPS PharmSciTech 20100901

• Cost analysis of flavocoxid compared to naproxen for management of mild to moderate OA.

  Current medical research and opinion 20100901

• Electrokinetic supercharging focusing in capillary zone electrophoresis of weakly ionizable analytes in environmental and biological samples.

  Electrophoresis 20100901

• Neurovascular orofacial pain.

  Journal of the American Dental Association (1939) 20100901

• Angioedema after nonsteroidal antiinflammatory drug initiation in a patient stable on an angiotensin-converting-enzyme inhibitor.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100815

• Theoretical and experimental investigation on the solid solubility and miscibility of naproxen in poly(vinylpyrrolidone).

  Molecular pharmaceutics 20100802

• Clinical trial: evaluation of gastric acid suppression with three doses of immediate-release esomeprazole in the fixed-dose combination of PN 400 (naproxen/esomeprazole magnesium) compared with naproxen 500 mg and enteric-coated esomeprazole 20 mg: a randomized, open-label, Phase I study in healthy volunteers.

  Alimentary pharmacology & therapeutics 20100801

• Clinical trial: the incidence of NSAID-associated endoscopic gastric ulcers in patients treated with PN 400 (naproxen plus esomeprazole magnesium) vs. enteric-coated naproxen alone.

  Alimentary pharmacology & therapeutics 20100801

• Ester prodrug-loaded electrospun cellulose acetate fiber mats as transdermal drug delivery systems.

  Journal of materials science. Materials in medicine 20100801

• Intra-renal oxygenation in rat kidneys during water loading: effects of cyclooxygenase (COX) inhibition and nitric oxide (NO) donation.

  Journal of magnetic resonance imaging : JMRI 20100801

• Determination of naproxen using DBS: evaluation & pharmacokinetic comparison of human plasma versus human blood DBS.

  Bioanalysis 20100801

• Naproxen degradation test to monitor Trametes versicolor activity in solid-state bioremediation processes.

  Journal of hazardous materials 20100715

• The role of the acquisition methods in the analysis of the non-steroidal anti-inflammatory drugs in Danube River by gas chromatography-mass spectrometry.

  Talanta 20100715

• Growth, shrinking, and breaking of pluronic micelles in the presence of drugs and/or beta-cyclodextrin, a study by small-angle neutron scattering and fluorescence spectroscopy.

  Langmuir : the ACS journal of surfaces and colloids 20100706

• Treating headache recurrence after emergency department discharge: a randomized controlled trial of naproxen versus sumatriptan.

  Annals of emergency medicine 20100701

• Kinetics of aqueous chlorination of some pharmaceuticals and their elimination from water matrices.

  Water research 20100701

• Second interlaboratory exercise on non-steroidal anti-inflammatory drug analysis in environmental aqueous samples.

  Talanta 20100615

• Evaluation of percutaneous absorption of naproxen from different liposomal formulations.

  Journal of pharmaceutical sciences 20100601

• Synthesis of novel dendrimers having aspartate grafts and their ability to enhance the aqueous solubility of model drugs.

  European journal of medicinal chemistry 20100601

• Effect of maximum OTC doses of naproxen sodium or acetaminophen on low-dose aspirin inhibition of serum thromboxane B2.

  Current medical research and opinion 20100601

• Naproxen metabolites interfere with certain bilirubin assays: elimination of interference by using a Roche bilirubin assay on the Hitachi 917 analyzer.

  American journal of clinical pathology 20100601

• Periorbital edema associated with separate courses of ibuprofen and naproxen.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100601

• Pharmacokinetics and tolerability of sumatriptan after single-dose administration of a fixed-dose combination tablet of sumatriptan/naproxen sodium 85/500 mg followed two hours later by subcutaneous sumatriptan 4- or 6-mg injection: a randomized, open-label, three-period crossover study in healthy volunteers.

  Clinical therapeutics 20100601

• DRESS-syndrome on sulfasalazine and naproxen treatment for juvenile idiopathic arthritis and reactivation of human herpevirus 6 in an 11-year-old Caucasian boy.

  Journal of clinical pharmacy and therapeutics 20100601

• On the use of carbon blacks as potential low-cost adsorbents for the removal of non-steroidal anti-inflammatory drugs from river water.

  Journal of hazardous materials 20100515

• Compression behaviour of anhydrous and hydrate forms of sodium naproxen.

  International journal of pharmaceutics 20100510

• D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model.

  NeuroImage 20100501

• A walking model to assess the onset of analgesia in osteoarthritis knee pain.

  Osteoarthritis and cartilage 20100501

• Efficacy and safety of naproxcinod in the treatment of patients with osteoarthritis of the knee: a 13-week prospective, randomized, multicenter study.

  Osteoarthritis and cartilage 20100501

• Analgesic and anti-inflammatory effects of oxaprozin and naproxen sodium after removal of impacted lower third molars: a randomized, double-blind, placebo-controlled crossover study.

  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20100501

• Meta-analysis of the efficacy and safety of naproxen sodium in the acute treatment of migraine.

  Headache 20100501

• Changes in salivary prostaglandin levels during menstrual migraine with associated dysmenorrhea.

  Headache 20100501

• Indirect reperfusion in the setting of symptomatic carotid occlusion by treatment of bilateral vertebral artery origin stenoses.

  Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 20100501

• Simultaneous dissolution of naproxen and flurbiprofen from a novel ternary gamma-cyclodextrin complex.

  Chemical & pharmaceutical bulletin 20100501

• Tenosynovitis caused by texting: an emerging disease.

  The Journal of the American Osteopathic Association 20100501

• Clinical pharmacokinetic drug interaction studies of gabapentin enacarbil, a novel transported prodrug of gabapentin, with naproxen and cimetidine.

  British journal of clinical pharmacology 20100501

• The adsorption of Naproxen enantiomers on the chiral stationary phase (R,R)-Whelk-O1 under reversed-phase conditions: the effect of mobile phase composition.

  Journal of chromatography. A 20100423

• [Visceral leishmaniasis infection in a rheumatoid arthritis patient treated with adalimumab: a case description and literature review].

  Enfermedades infecciosas y microbiologia clinica 20100401

• High-dose naproxen aggravates pancreatic fibrosis in a rat model of chronic pancreatitis.

  Pancreas 20100401

• Can L(+)-lactate be used as a marker of experimentally induced inflammation in rats?

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20100401

• Infusions of albumin increase free fraction of naproxen in healthy volunteers: a randomized crossover study.

  Acta anaesthesiologica Scandinavica 20100401

• Biodegradability of pharmaceutical industrial wastewater and formation of recalcitrant organic compounds during aerobic biological treatment.

  Bioresource technology 20100401

• Biodegradation of the analgesic naproxen by Trametes versicolor and identification of intermediates using HPLC-DAD-MS and NMR.

  Bioresource technology 20100401

• Degradation of naproxen and carbamazepine in spiked sludge by slurry and solid-phase Trametes versicolor systems.

  Bioresource technology 20100401

• Screening agents for preventive efficacy in a bladder cancer model: study design, end points, and gefitinib and naproxen efficacy.

  The Journal of urology 20100401

• Flow induced dispersion analysis quantifies noncovalent interactions in nanoliter samples.

  Journal of the American Chemical Society 20100331

• The interplay of membrane formation and drug release in solution-cast films of polylactide polymers.

  International journal of pharmaceutics 20100330

• Retention of Naproxen enantiomers on the chiral stationary phase Whelk-O1 under reversed-phase conditions. A reconsideration of the adsorption mechanism in the light of new experimental data.

  Journal of chromatography. A 20100305

• Optimizing the polarization matrix for ex situ dynamic nuclear polarization.

  Journal of the American Chemical Society 20100303

• Impact of chronic inflammation on the pharmacokinetic-pharmacodynamic relationship of naproxen.

  European journal of pain (London, England) 20100301

• Quality-by-Design (QbD): an integrated process analytical technology (PAT) approach for real-time monitoring and mapping the state of a pharmaceutical coprecipitation process.

  Journal of pharmaceutical sciences 20100301

• Clinical relevance of C-reactive protein in ankylosing spondylitis and evaluation of the NSAIDs/coxibs' treatment effect on C-reactive protein.

  Rheumatology (Oxford, England) 20100301

• Effects of the nonsteroidal anti-inflammatory drug naproxen on human erythrocytes and on cell membrane molecular models.

  Biophysical chemistry 20100301

• Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346).

  British journal of pharmacology 20100301

• Effect of oppositely charged polymer and dissolution media on rheology of spray-dried ionic complexes.

  AAPS PharmSciTech 20100301

• Distinct pharmacokinetic profile and safety of a fixed-dose tablet of sumatriptan and naproxen sodium for the acute treatment of migraine.

  Headache 20100301

• [Necrotizing cutaneous vasculitis with massive gastrointestinal bleeding following naproxen treatment].

  Harefuah 20100301

• Preparative enantioseparation of (+/-)-N-(3,4-cis-3-decyl-1,2,3,4-tetrahydrophenanthren-4-yl)-3,5-dinitrobenzamide by centrifugal partition chromatography.

  Journal of chromatography. A 20100219

• On the enantioselectivity of the mass transfer kinetics and the adsorption equilibrium of Naproxen on the chiral stationary phase (R,R)-Whelk-O1 under reversed-phase conditions.

  Journal of chromatography. A 20100219

• Modeling the influence of cyclodextrins on oral absorption of low solubility drugs: II. Experimental validation.

  Biotechnology and bioengineering 20100201

• Sorption of the pharmaceuticals carbamazepine and naproxen to dissolved organic matter: role of structural fractions.

  Water research 20100201

• High concentrations of commonly used drugs can inhibit the in vitro glucuronidation of bisphenol A and nonylphenol in rats.

  Xenobiotica; the fate of foreign compounds in biological systems 20100201

• Protective effects of selective and non-selective cyclooxygenase inhibitors in an animal model of chronic stress.

  Neuroscience bulletin 20100201

• A molecular mechanism for ibuprofen-mediated RhoA inhibition in neurons.

  The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120

• Features of the adsorption of Naproxen on the chiral stationary phase (S,S)-Whelk-O1 under reversed-phase conditions.

  Journal of chromatography. A 20100115

• Identification and enantioselective gas chromatographic mass-spectrometric separation of O-desmethylnaproxen, the main metabolite of the drug naproxen, as a new environmental contaminant.

  Journal of chromatography. A 20100115

• Chemiluminescence determination of naproxen based on europium(III)-sensitized KIO4-H2O2 reaction.

  Luminescence : the journal of biological and chemical luminescence 20100101

• Investigating the chlorination of acidic pharmaceuticals and by-product formation aided by an experimental design methodology.

  Water research 20100101

• The ethanol metabolite acetaldehyde increases paracellular drug permeability in vitro and oral bioavailability in vivo.

  The Journal of pharmacology and experimental therapeutics 20100101

• Alterations in skin immune response throughout chronic UVB irradiation-skin cancer development and prevention by naproxen.

  Photochemistry and photobiology 20100101

• Effects of acetaminophen, naproxen, and acetylsalicylic acid on tapentadol pharmacokinetics: results of two randomized, open-label, crossover, drug-drug interaction studies.

  Pharmacotherapy 20100101

• Overexpression of cyclooxygenase-2 in rat oral cancers and prevention of oral carcinogenesis in rats by selective and nonselective COX inhibitors.

  Cancer prevention research (Philadelphia, Pa.) 20100101

• Bone infarctions in a patient with systemic lupus erythematosus and anti-cardiolipin antibodies.

  Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20100101

• Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT.

  PloS one 20100101

• Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDS in the treatment of ankylosing spondylitis.

  PharmacoEconomics 20100101

• Sumatriptan-naproxen fixed combination for acute treatment of migraine: a critical appraisal.

  Drug design, development and therapy 20100101

• Chronic nonbacterial osteomyelitis in childhood: prospective follow-up during the first year of anti-inflammatory treatment.

  Arthritis research & therapy 20100101

• Adult-Onset Still Disease (AOSD).

  Journal of the American Board of Family Medicine : JABFM 20100101

• In vitro dissolution profile comparison of an anti-migraine combinational drug in dosage form.

  Se pu = Chinese journal of chromatography 20100101

• APP intracellular domain impairs adult neurogenesis in transgenic mice by inducing neuroinflammation.

  PloS one 20100101

• Evaluation of phenoxybenzamine in the CFA model of pain following gene expression studies and connectivity mapping.

  Molecular pain 20100101

• Pharmaceutical advertisements, citations, and trust.

  Family medicine 20100101

• Effects of analgesics on pre- and post-separator pain.

  Today's FDA : official monthly journal of the Florida Dental Association 20100101

• Cryoprotectants for freeze drying of drug nano-suspensions: effect of freezing rate.

  Journal of pharmaceutical sciences 20091201

• Differential afferent sensitivity to mucosal lipopolysaccharide from Salmonella typhimurium and Escherichia coli in the rat jejunum.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20091201

• NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease.

  The Journal of clinical investigation 20091201

• Eisenmenger syndrome and juvenile rheumatoid arthritis--a case of double diagnosis.

  Kardiologia polska 20091201

• Lipase-catalyzed esterification of (S)-naproxen ethyl ester in supercritical carbon dioxide.

  Journal of microbiology and biotechnology 20091201

• Gouty tophi caused limited knee range of motion: a case report.

  Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20091201

• Multiple dual-mode countercurrent chromatography applied to chiral separations using a (S)-naproxen derivative as chiral selector.

  Journal of chromatography. A 20091127

• Naproxen-induced generalized bullous fixed drug eruption.

  Dermatology online journal 20091115

• A conditional sequential sampling procedure for drug safety surveillance.

  Statistics in medicine 20091110

• Differences in the interaction between aryl propionic acid derivatives and poly(vinylpyrrolidone) K30: A multi-methodological approach.

  Journal of pharmaceutical sciences 20091101

• Effects of liquisolid formulations on dissolution of naproxen.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20091101

• Fluorescent polyacrylamide nanoparticles for naproxen recognition.

  Analytical and bioanalytical chemistry 20091101

• Degradation and adsorption of selected pharmaceuticals and personal care products (PPCPs) in agricultural soils.

  Chemosphere 20091101

• Chemopreventive efficacy of naproxen and nitric oxide-naproxen in rodent models of colon, urinary bladder, and mammary cancers.

  Cancer prevention research (Philadelphia, Pa.) 20091101

• The regeneration of the tail fin actinotrichia of carp (Cyprinus carpio, Linnaeus, 1758) under the action of naproxen.

  Brazilian journal of biology = Revista brasleira de biologia 20091101

• Oral contraceptive pill for heavy menstrual bleeding.

  The Cochrane database of systematic reviews 20091007

• A novel second-order standard addition analytical method based on data processing with multidimensional partial least-squares and residual bilinearization.

  Analytica chimica acta 20091005

• Preparation and characterization of nanoparticles based on dextran-drug conjugates.

  Journal of colloid and interface science 20091001

• Platelet inhibitory effects of OTC doses of naproxen sodium compared with prescription dose naproxen sodium and low-dose aspirin.

  Current medical research and opinion 20091001

• Role of aromatic amino acid tryptophan UVA-photoproducts in the determination of drug photosensitization mechanism: a comparison between methylene blue and naproxen.

  Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20091001

• Hyperkalemia-induced paralysis.

  Pharmacotherapy 20091001

• Fixed drug eruptions: a case report and review of the literature.

  Cutis 20091001

• Formation of naproxen-polylactic acid nanoparticles from supercritical solutions and their characterization in the aerosol phase.

  Physical chemistry chemical physics : PCCP 20090928

• Effects of the cyclooxygenase inhibiting nitric oxide donator naproxcinod versus naproxen on systemic blood pressure in patients with osteoarthritis.

  The American journal of cardiology 20090915

• Effect of increasing concentration of ammonium acetate as an additive in supercritical fluid chromatography using CO2-methanol mobile phase.

  Journal of chromatography. A 20090904

• Influence of N-terminal domain histidine and proline residues on the substrate selectivities of human UDP-glucuronosyltransferase 1A1, 1A6, 1A9, 2B7, and 2B10.

  Drug metabolism and disposition: the biological fate of chemicals 20090901

• Determination of pKa values of nonsteroidal antiinflammatory drug-oxicams by RP-HPLC and their analysis in pharmaceutical dosage forms.

  Journal of separation science 20090901

• A phase II trial of calcitriol and naproxen in recurrent prostate cancer.

  Anticancer research 20090901

• A randomized, controlled, dose-ranging study investigating single doses of GW406381, naproxen sodium, or placebo in patients with acute pain after third molar tooth extraction.

  The Clinical journal of pain 20090901

• A unique presentation of complex regional pain syndrome type I treated with a continuous sciatic peripheral nerve block and parenteral ketamine infusion: a case report.

  Pain medicine (Malden, Mass.) 20090901

• Rapid molecular imaging using attenuated total internal reflection planar array infrared spectroscopy for the analysis of counterfeit pharmaceutical tablets.

  Applied spectroscopy 20090901

• Pain relief balancing act. For people with heart disease, naproxen may be the best choice for easing pain.

  Harvard heart letter : from Harvard Medical School 20090901

• Determination of naproxen in human urine by high-performance liquid chromatography with direct electrogenerated chemiluminescence detection.

  Talanta 20090815

• Rational optimization of the Whelk-O1 chiral stationary phase using molecular dynamics simulations.

  Journal of chromatography. A 20090807

• Influence of chiral ionic liquids on stereoselective fluorescence quenching by photoinduced electron transfer in a naproxen dyad.

  The journal of physical chemistry. B 20090806

• Effect of chirality on PVP/drug interaction within binary physical mixtures of ibuprofen, ketoprofen, and naproxen: a DSC study.

  Chirality 20090801

• Consistency of response to sumatriptan/naproxen sodium in a placebo-controlled, crossover study.

  Cephalalgia : an international journal of headache 20090801

• Glycerolysis of acyl glucuronides as an artifact of in vitro drug metabolism incubations.

  Drug metabolism and disposition: the biological fate of chemicals 20090801

• Amidine derived inhibitors of acid-sensing ion channel-3 (ASIC3).

  Bioorganic & medicinal chemistry letters 20090801

• Synthesis and preliminary evaluation in vitro of novel naproxen-dendritic peptide conjugates.

  Drug delivery 20090801

• Interventions for pain with intrauterine device insertion.

  The Cochrane database of systematic reviews 20090708

• NSAID-induced antral ulcers are associated with distinct changes in mucosal gene expression.

  Alimentary pharmacology & therapeutics 20090701

• Arrestin3 mediates D(2) dopamine receptor internalization.

  Synapse (New York, N.Y.) 20090701

• Fixed-dose sumatriptan and naproxen in poor responders to triptans with a short half-life.

  Headache 20090701

• Combination treatment for menstrual migraine and dysmenorrhea using sumatriptan-naproxen: two randomized controlled trials.

  Obstetrics and gynecology 20090701

• Protective effects of licofelone, a 5-lipoxygenase and cyclo-oxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: a first multicentre clinical trial using quantitative MRI.

  Annals of the rheumatic diseases 20090601

• The impact of selective and non-selective non-steroid anti-inflammatory drugs on secondary hemostasis in healthy volunteers.

  Thrombosis research 20090601

• Hepatic stellate cells promote hepatocyte engraftment in rat liver after prostaglandin-endoperoxide synthase inhibition.

  Gastroenterology 20090601

• The membrane-activity of Ibuprofen, Diclofenac, and Naproxen: a physico-chemical study with lecithin phospholipids.

  Biochimica et biophysica acta 20090601

• Efficacy, safety, and tolerability of the cyclooxygenase-inhibiting nitric oxide donator naproxcinod in treating osteoarthritis of the hip or knee.

  The Journal of rheumatology 20090601

• Convenient synthesis of Ibuprofen and naproxen aminoacyl, dipeptidoyl and ester derivatives.

  Chemical biology & drug design 20090601

• Celecoxib in the treatment of primary dysmenorrhea: results from two randomized, double-blind, active- and placebo-controlled, crossover studies.

  Clinical therapeutics 20090601

• Enhanced dissolution rate and synchronized release of drugs in binary systems through formulation: Amorphous naproxen-cimetidine mixtures prepared by mechanical activation.

  Journal of controlled release : official journal of the Controlled Release Society 20090521

• Development and validation of a composite disease activity score for juvenile idiopathic arthritis.

  Arthritis and rheumatism 20090515

• Determination of widely used non-steroidal anti-inflammatory drugs in water samples by in situ derivatization, continuous hollow fiber liquid-phase microextraction and gas chromatography-flame ionization detector.

  Analytica chimica acta 20090508

• Idiopathic chondrolysis condition in two young, wild-caught Cynomolgus monkeys (Macaca fascicularis) reared in captivity.

  Veterinary pathology 20090501

• A randomized, controlled study on the influence of acetaminophen, diclofenac, or naproxen on aspirin-induced inhibition of platelet aggregation.

  European journal of pharmacology 20090501

• Enantiomeric separation of acidic compounds by nano-liquid chromatography with methylated-beta-cyclodextrin as a mobile phase additive.

  Journal of separation science 20090501

• Naproxcinod, a new cyclooxygenase-inhibiting nitric oxide donator (CINOD).

  Expert opinion on biological therapy 20090501

• Long open tubular molecule imprinted polymer capillary columns with excellent separation efficiencies in chiral and non-chiral separation by capillary electrochromatography.

  Electrophoresis 20090501

• Naproxen induced pustular eruption.

  Indian pediatrics 20090501

• Fatal acute hepatitis after sequential treatment with levofloxacin, doxycycline, and naproxen in a patient presenting with acute Mycoplasma pneumoniae infection.

  Clinical therapeutics 20090501

• Flavocoxid is as effective as naproxen for managing the signs and symptoms of osteoarthritis of the knee in humans: a short-term randomized, double-blind pilot study.

  Nutrition research (New York, N.Y.) 20090501

• Cardiovascular risks of nonsteroidal antiinflammatory drugs in patients after hospitalization for serious coronary heart disease.

  Circulation. Cardiovascular quality and outcomes 20090501

• [Fever in patients with cancer].

  Rinsho byori. The Japanese journal of clinical pathology 20090501

• Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis.

  The Cochrane database of systematic reviews 20090415

• Multimechanistic (sumatriptan-naproxen) early intervention for the acute treatment of migraine.

  Neurology 20090414

• Counter-flow electrokinetic supercharging for the determination of non-steroidal anti-inflammatory drugs in water samples.

  Journal of chromatography. A 20090410

• Diffusion of an ionic drug in micellar aqueous solutions.

  Langmuir : the ACS journal of surfaces and colloids 20090409

• Chemoenzymatic and microbial dynamic kinetic resolutions.

  Chirality 20090401

• Assessment of the pharmaceutical active compounds removal in wastewater treatment systems at enantiomeric level. Ibuprofen and naproxen.

  Chemosphere 20090401

• A randomized, placebo-controlled study of the effects of naproxen, aspirin, celecoxib or clopidogrel on gastroduodenal mucosal healing.

  Alimentary pharmacology & therapeutics 20090401

• Rationale, design, and governance of Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen Or Naproxen (PRECISION), a cardiovascular end point trial of nonsteroidal antiinflammatory agents in patients with arthritis.

  American heart journal 20090401

• Can treatment with nonsteroidal anti-inflammatory drugs protect from dementia?

  Archives of neurology 20090401

• Effect of honey on the common cold.

  Archives of medical research 20090401

• Flocculation of polymer stabilized nanocrystal suspensions to produce redispersible powders.

  Drug development and industrial pharmacy 20090301

• Physicomechanical properties of naproxen-loaded microparticles prepared from Eudragit l100.

  AAPS PharmSciTech 20090301

• Cyclooxygenase-inhibiting nitric oxide donators for osteoarthritis.

  Trends in pharmacological sciences 20090301

• Alzheimer's Disease Anti-inflammatory Prevention Trial: design, methods, and baseline results.

  Alzheimer's & dementia : the journal of the Alzheimer's Association 20090301

• Feasibility and efficacy of intraarticular steroids (IAS) in juvenile idiopathic arthritis (JIA).

  Indian pediatrics 20090301

• Saturation transfer difference nuclear magnetic resonance study on the specific binding of ligand to protein.

  Analytical biochemistry 20090215

• Novel beta-cyclodextrin derivative functionalized polymethacrylate-based monolithic columns for enantioselective separation of ibuprofen and naproxen enantiomers in capillary electrochromatography.

  Journal of chromatography. A 20090206

• High-speed microchip electrophoresis method for the separation of (R,S)-naproxen.

  Chirality 20090201

• Consideration of the linear concentration increase of the unbound drug fraction in plasma.

  Journal of pharmaceutical sciences 20090201

• Naproxen-PC: a GI safe and highly effective anti-inflammatory.

  Inflammopharmacology 20090201

• Cardiovascular risk associated with nonsteroidal anti-inflammatory drugs.

  Current rheumatology reports 20090201

• Effect of CYP2C9*3 allele on the pharmacokinetics of naproxen in Korean subjects.

  Archives of pharmacal research 20090201

• Bioavailability of two oral-tablet and two oral-suspension formulations of naproxen sodium/paracetamol (acetaminophen): single-dose, randomized, open-label, two-period crossover comparisons in healthy Mexican adult subjects.

  Clinical therapeutics 20090201

• Effect of surfactant mixing on partitioning of model hydrophobic drug, naproxen, between aqueous and micellar phases.

  The journal of physical chemistry. B 20090129

• Single dose oral naproxen and naproxen sodium for acute postoperative pain in adults.

  The Cochrane database of systematic reviews 20090121

• Naproxen-induced anemia and hypoalbuminemia in a 16-month-old child.

  Clinical pediatrics 20090101

• Estimation of drug solubility in polymers via differential scanning calorimetry and utilization of the fox equation.

  Pharmaceutical development and technology 20090101

• Spurious hyperbilirubinemia caused by naproxen.

  Clinical biochemistry 20090101

• A prospective study comparing celecoxib with naproxen in children with juvenile rheumatoid arthritis.

  The Journal of rheumatology 20090101

• Fish skin as a model membrane: structure and characteristics.

  The Journal of pharmacy and pharmacology 20090101

• Effect of naproxen on the hypothalamic-pituitary-adrenal axis in healthy volunteers.

  British journal of clinical pharmacology 20090101

• Simultaneous determination of the two non-steroidal anti-inflammatory drugs ; diflunisal and naproxen in their tablets by chemometric spectrophotometry and HPLC.

  Pakistan journal of pharmaceutical sciences 20090101

• Preparation of microparticles of naproxen with Eudragit RS and talc by spherical crystallization technique.

  Pharmaceutical development and technology 20090101

• Effects of alcohol and buffer treatments on the activity and enantioselectivity of Candida rugosa lipase.

  Preparative biochemistry & biotechnology 20090101

• Fast attrition-enhanced deracemization of naproxen by a gradual in situ feed.

  Angewandte Chemie (International ed. in English) 20090101

• Design and synthesis of some (S)-2-(6-methoxynaphthalen-2-yl)-N-substituted ethyl propanamide derivatives as potent non-ulcerogenic anti-inflammatory and analgesic agents.

  Arzneimittel-Forschung 20090101

• [Insufficient evidence for oral glucocorticoids as first-line therapy for acute gout].

  Nederlands tijdschrift voor geneeskunde 20090101

• Nonsteroidal anti-inflammatory drug hypersensitivity syndrome. A multicenter study. I. Clinical findings and in vitro diagnosis.

  Journal of investigational allergology & clinical immunology 20090101

• Physiotherapy alone or in combination with corticosteroid injection for acute lateral epicondylitis in general practice: a protocol for a randomised, placebo-controlled study.

  BMC musculoskeletal disorders 20090101

• Macrophage activation syndrome in an inadequately treated patient with systemic onset juvenile idiopathic arthritis.

  Kathmandu University medical journal (KUMJ) 20090101

• Physico-chemical and technological properties of sodium naproxen granules prepared in a high-shear mixer-granulator.

  Journal of pharmaceutical sciences 20081201

• Hydroxychloroquine-induced hyperpigmentation: the staining pattern.

  Journal of cutaneous pathology 20081201

• The risk of acute myocardial infarction with etodolac is not increased compared to naproxen: a historical cohort analysis of a generic COX-2 selective inhibitor.

  Journal of cardiovascular pharmacology and therapeutics 20081201

• Tolerability and efficacy of a combination of paracetamol and caffeine in the treatment of tension-type headache: a randomised, double-blind, double-dummy, cross-over study versus placebo and naproxen sodium.

  The journal of headache and pain 20081201

• A lipid extract of Perna canaliculus affects the expression of pro-inflammatory cytokines in a rat adjuvant-induced arthritis model.

  European annals of allergy and clinical immunology 20081201

• [Application of genetic algorithm in formulation optimization of microemulsion for transdermal delivery].

  Yao xue xue bao = Acta pharmaceutica Sinica 20081201

• Nanocomposites of 2-arylpropionic acid drugs based on Mg-Al layered double hydroxide for dissolution enhancement.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20081115

• Blockade of cytosolic phospholipase A2 alpha prevents experimental autoimmune encephalomyelitis and diminishes development of Th1 and Th17 responses.

  Journal of neuroimmunology 20081115

• Supramolecular solid-phase extraction of ibuprofen and naproxen from sewage based on the formation of mixed supramolecular aggregates prior to their liquid chromatographic/photometric determination.

  Journal of chromatography. A 20081107

• Does the varied use of NSAIDs explain the differences in the risk of myocardial infarction?

  Journal of internal medicine 20081101

• Comparison of naproxen with placebo for the management of noncyclical breast pain: a randomized, double-blind, controlled trial.

  World journal of surgery 20081101

• Hydroformylation and carbonylation processes: new trends in the synthesis of pharmaceuticals.

  Current opinion in drug discovery & development 20081101

• Aspirin, NSAIDs, and cardiovascular risk: is there a link?

  The American journal of medicine 20081101

• Skin disposition of menthol after its application in the presence of drug substances.

  Biopharmaceutics & drug disposition 20081101

• Seeds of doubt--ADVANTAGE no one.

  International journal of clinical practice 20081101

• A randomised, double-blind study comparing lumiracoxib with naproxen for acute musculoskeletal pain.

  International journal of clinical practice 20081101

• Advances in stir bar sorptive extraction for the determination of acidic pharmaceuticals in environmental water matrices Comparison between polyurethane and polydimethylsiloxane polymeric phases.

  Journal of chromatography. A 20081031

• Synthesis of succinimidyl-(S)-naproxen ester and its application for indirect enantioresolution of penicillamine by reversed-phase high-performance liquid chromatography.

  Journal of chromatography. A 20081031

• The effects of etodolac, nimesulid and naproxen sodium on the frequency of sister chromatid exchange after enclused third molars surgery.

  Yonsei medical journal 20081031

• Theoretical study of the phototoxicity of naproxen and the active form of nabumetone.

  The journal of physical chemistry. A 20081030

• Localized episcleritis-like lesions on both eyes in a patient with para nasal sinusitis.

  International ophthalmology 20081001

• Fate of the nonsteroidal anti-inflammatory drug naproxen in agricultural soil receiving liquid municipal biosolids.

  Environmental toxicology and chemistry 20081001

• Time-course evaluation and treatment of skin inflammatory immune response after ultraviolet B irradiation.

  Cytokine 20081001

• Non-operative management of femoral neuropathy secondary to a traumatic iliacus haematoma in an adolescent.

  The Journal of bone and joint surgery. British volume 20081001

• New therapies may ease headache symptoms. A two-drug combo and two kinds of oxygen therapy show promise for relieving migraine and cluster headache pain.

  DukeMedicine healthnews 20081001

• Drug contamination of the equine racetrack environment: a preliminary examination.

  Journal of veterinary pharmacology and therapeutics 20081001

• Prostaglandin inhibitors in the treatment of single-system Langerhans cell histiocytosis: pharmacologic rationale and report of two cases.

  Journal of pediatric hematology/oncology 20081001

• Subarachnoid haemorrhage: possibly caused by the illegitimate use of sildenafil citrate.

  The Journal of the Association of Physicians of India 20081001

• Influence of crystal hydration on the mechanical properties of sodium naproxen.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080901

• Kinetic brain analysis and whole-body imaging in monkey of [11C]MNPA: a dopamine agonist radioligand.

  Synapse (New York, N.Y.) 20080901

• Cyclooxygenase inhibitors down regulate P-glycoprotein in human colorectal Caco-2 cell line.

  Pharmaceutical research 20080901

• Comparison of oral naproxen and intrauterine lignocaine instillation for pain relief during hysterosalpingography.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20080901

• Sumatriptan/naproxen sodium combination for the treatment of migraine.

  Expert review of neurotherapeutics 20080901

• Anti-inflammatory drugs fall short in Alzheimer's disease.

  Nature medicine 20080901

• Reiter's syndrome in a patient with polyarthritis and nail involvement.

  Iranian journal of allergy, asthma, and immunology 20080901

• Ionic liquid-based dynamic liquid-phase microextraction: application to the determination of anti-inflammatory drugs in urine samples.

  Journal of chromatography. A 20080815

• Design and characterization of a new miniaturized rotating disk equipment for in vitro dissolution rate studies.

  Journal of pharmaceutical sciences 20080801

• Primary prevention of adverse gastroduodenal effects from short-term use of non-steroidal anti-inflammatory drugs by omeprazole 20 mg in healthy subjects: a randomized, double-blind, placebo-controlled study.

  Digestive diseases and sciences 20080801

• A comparison of the blood pressure changes of lumiracoxib with those of ibuprofen and naproxen.

  Journal of clinical hypertension (Greenwich, Conn.) 20080801

• Identification and quantification of ibuprofen, naproxen, ketoprofen and diclofenac present in waste-waters, as their trimethylsilyl derivatives, by gas chromatography mass spectrometry.

  Talanta 20080730

• Monitoring the synthetic procedures of commercial drugs by 2H NMR spectroscopy: the case of ibuprofen and naproxen.

  Talanta 20080730

• Multimechanistic (sumatriptan-naproxen) early intervention for the acute treatment of migraine.

  Neurology 20080708

• Drug permeability across a phospholipid vesicle-based barrier 4. The effect of tensides, co-solvents and pH changes on barrier integrity and on drug permeability.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080703

• Naproxen suppository for perineal pain after vaginal delivery.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20080701

• Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib.

  Archives of neurology 20080701

• Oral colon targeted delivery systems for treatment of inflammatory bowel diseases: synthesis, in vitro and in vivo assessment.

  International journal of pharmaceutics 20080624

• A fixed-dose combination of sumatriptan and naproxen for migraine.

  The Medical letter on drugs and therapeutics 20080616

• Lipid nanoparticles for prolonged topical delivery: an in vitro and in vivo investigation.

  International journal of pharmaceutics 20080605

• The pH-controlled dual-drug release from mesoporous bioactive glass/polypeptide graft copolymer nanomicelle composites.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080601

• Adsorption characteristics of selected pharmaceuticals and an endocrine disrupting compound-Naproxen, carbamazepine and nonylphenol-on activated carbon.

  Water research 20080601

• Risk of ischaemic cardiovascular events from selective cyclooxygenase-2 inhibitors in osteoarthritis.

  Pharmacoepidemiology and drug safety 20080601

• Evaluation of the quality of four Mexican drug products containing sodium naproxen.

  Journal of clinical pharmacy and therapeutics 20080601

• Images from headache: a costly attack of migraine.

  Headache 20080601

• Dissolution and permeation properties of naproxen from solid-state systems with chitosan.

  Drug delivery 20080601

• Use of oral prednisolone or naproxen for the treatment of gout arthritis: a double-blind, randomised equivalence trial.

  Lancet (London, England) 20080531

• Features of the adsorption of naproxen enantiomers on weak chiral anion-exchangers in nonlinear chromatography.

  Journal of chromatography. A 20080523

• Design, synthesis and in vitro evaluation of vinyl ether type polymeric prodrugs of ibuprofen, ketoprofen and naproxen.

  International journal of pharmaceutics 20080522

• Development of a reaction-limited model of dissolution: application to official dissolution tests experiments.

  International journal of pharmaceutics 20080501

• Clinical trial: comparison of the gastrointestinal safety of lumiracoxib with traditional nonselective nonsteroidal anti-inflammatory drugs early after the initiation of treatment--findings from the Therapeutic Arthritis Research and Gastrointestinal Event Trial.

  Alimentary pharmacology & therapeutics 20080501

• Less small-bowel injury with lumiracoxib compared with naproxen plus omeprazole.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20080501

• Patterns of pregnancy exposure to prescription FDA C, D and X drugs in a Canadian population.

  Journal of perinatology : official journal of the California Perinatal Association 20080501

• Identification of the carboxylic acid functionality by using electrospray ionization and ion-molecule reactions in a modified linear quadrupole ion trap mass spectrometer.

  Analytical chemistry 20080501

• A double-blind, randomized, placebo-controlled, single-dose study of the cyclooxygenase-2 inhibitor, GW406381, as a treatment for acute migraine.

  European journal of neurology 20080401

• Pharmacological treatment of heterotopic ossification following hip and acetabular surgery.

  Expert opinion on pharmacotherapy 20080401

• Efficacy and tolerability of lumiracoxib 200 mg once daily for treatment of primary dysmenorrhea: results from two randomized controlled trials.

  Journal of women's health (2002) 20080401

• Acute allergic interstitial nephritis and eosinophiluria.

  Kidney international 20080401

• Impact of naproxen sodium at over-the-counter doses on cyclooxygenase isoforms in human volunteers.

  International journal of clinical pharmacology and therapeutics 20080401

• Particle design of naproxen-disintegrant agglomerates for direct compression by a crystallo-co-agglomeration technique.

  International journal of pharmaceutics 20080303

• Effect of arginine hydrochloride and hydroxypropyl cellulose as stabilizers on the physical stability of high drug loading nanosuspensions of a poorly soluble compound.

  International journal of pharmaceutics 20080303

• Endoscopic ulcer rates in healthy subjects associated with use of aspirin (81 mg q.d.) alone or coadministered with celecoxib or naproxen: a randomized, 1-week trial.

  Digestive diseases and sciences 20080301

• Infusion of albumin attenuates changes in serum protein binding of drugs in surgical patients compared with volume replacement with HAES.

  Acta anaesthesiologica Scandinavica 20080301

• Sensitivity enhancement for the analysis of naproxen in tap water by solid-phase extraction coupled in-line to capillary electrophoresis.

  Journal of separation science 20080301

• Cyclooxygenase-2 inhibitors and most traditional nonsteroidal anti-inflammatory drugs cause similar moderately increased risks of cardiovascular disease.

  Journal of cardiovascular pharmacology and therapeutics 20080301

• Cyclooxygenase-2 inhibition improves amyloid-beta-mediated suppression of memory and synaptic plasticity.

  Brain : a journal of neurology 20080301

• Effect of drying methods on swelling, erosion and drug release from chitosan-naproxen sodium complexes.

  AAPS PharmSciTech 20080301

• Preparation of spherical crystal agglomerates of naproxen containing disintegrant for direct tablet making by spherical crystallization technique.

  AAPS PharmSciTech 20080301

• Colonic release and reduced intestinal tissue damage of coated tablets containing naproxen inclusion complex.

  International journal of pharmaceutics 20080227

• Binding characteristics of bovine serum albumin encapsulated in sol-gel glasses: an alternative for protein interaction studies.

  Analytical biochemistry 20080215

• Photocatalytic degradation of non-steroidal anti-inflammatory drugs with TiO2 and simulated solar irradiation.

  Water research 20080201

• Structural basis for the binding of naproxen to human serum albumin in the presence of fatty acids and the GA module.

  Acta crystallographica. Section F, Structural biology and crystallization communications 20080201

• Sensitization of meningeal nociceptors: inhibition by naproxen.

  The European journal of neuroscience 20080201

• Fluorescent high-performance liquid chromatographic analysis of vigabatrin enantiomers after derivatizing with naproxen acyl chloride.

  Journal of chromatography. A 20080118

• Pharmacologic evaluation of pressor and visceromotor reflex responses to bladder distension.

  Neurourology and urodynamics 20080101

• Effects of cyclooxygenase inhibition on canine coronary artery blood flow and thrombosis.

  American journal of physiology. Heart and circulatory physiology 20080101

• Naproxen, meloxicam and methylprednisolone inhibit urokinase plasminogen activator and inhibitor and gelatinases expression during the early stage of osteoarthritis.

  Clinica chimica acta; international journal of clinical chemistry 20080101

• Airplane headache: a neurologist's personal experience.

  Cephalalgia : an international journal of headache 20080101

• The effect of naproxen sodium on experimental otitis media.

  Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat 20080101

• Rapid characterization of drug-drug interaction in plasma protein binding using a surface plasmon resonance biosensor.

  Drug metabolism and pharmacokinetics 20080101

• Singlet oxygen scavenging activity of non-steroidal anti-inflammatory drugs.

  Redox report : communications in free radical research 20080101

• Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.

  Water science and technology : a journal of the International Association on Water Pollution Research 20080101

• Analysis of the precision and sensitivity to change of different approaches to assess cartilage loss by quantitative MRI in a longitudinal multicentre clinical trial in patients with knee osteoarthritis.

  Arthritis research & therapy 20080101

• Prednisolone and naproxen both work for pain relief in acute gout.

  Medscape journal of medicine 20080101

• Prostaglandins are necessary and sufficient to induce contextual fear learning impairments after interleukin-1 beta injections into the dorsal hippocampus.

  Neuroscience 20071219

• Effects of selective COX-2 inhibition on prostanoids and platelet physiology in young healthy volunteers.

  Journal of thrombosis and haemostasis : JTH 20071201

• Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet.

  Journal of clinical pharmacology 20071201

• Early detection of adverse drug events within population-based health networks: application of sequential testing methods.

  Pharmacoepidemiology and drug safety 20071201

• NSAIDs, coxibs, CINOD and H2S-releasing NSAIDs: what lies beyond the horizon.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20071201

• Fever of unknown origin: focused diagnostic approach based on clinical clues from the history, physical examination, and laboratory tests.

  Infectious disease clinics of North America 20071201

• Etoricoxib: new drug. Avoid using cox-2 inhibitors for pain.

  Prescrire international 20071201

• Clinical and pathologic manifestations of necrobiosis lipoidica-like skin involvement in sarcoidosis.

  Joint, bone, spine : revue du rhumatisme 20071201

• Signal suppression/enhancement in HPLC-ESI-MS/MS from concomitant medications.

  Biomedical chromatography : BMC 20071101

• Polymorphic variants of CYP2C9: mechanisms involved in reduced catalytic activity.

  Molecular pharmacology 20071101

• Human renal cortical and medullary UDP-glucuronosyltransferases (UGTs): immunohistochemical localization of UGT2B7 and UGT1A enzymes and kinetic characterization of S-naproxen glucuronidation.

  The Journal of pharmacology and experimental therapeutics 20071101

• Non-carboxylic analogues of naproxen: design, synthesis, and pharmacological evaluation of some 1,3,4-oxadiazole/thiadiazole and 1,2,4-triazole derivatives.

  Archiv der Pharmazie 20071101

• Correlated theoretical, spectroscopic and X-ray crystallographic studies of a non-covalent molecularly imprinted polymerisation system.

  The Analyst 20071101

• Inflammatory pseudotumor of the liver successfully treated with nonsteroidal anti-inflammatory drugs: a challenge diagnosis for one not so rare entity.

  European journal of gastroenterology & hepatology 20071101

• Improved compaction and packing properties of naproxen agglomerated crystals obtained by spherical crystallization technique.

  Drug development and industrial pharmacy 20071101

• Celecoxib plus aspirin versus naproxen and lansoprazole plus aspirin: a randomized, double-blind, endoscopic trial.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20071001

• Frovatriptan vs. transdermal oestrogens or naproxen sodium for the prophylaxis of menstrual migraine.

  The journal of headache and pain 20071001

• Elucidation of the naproxen sodium adsorption onto activated carbon prepared from waste apricot: kinetic, equilibrium and thermodynamic characterization.

  Journal of hazardous materials 20070930

• Combination of sumatriptan and naproxen for migraine.

  JAMA 20070919

• Determination of non-steroidal anti-inflammatory drugs in pharmaceuticals and human serum by dual-mode gradient HPLC and fluorescence detection.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070915

• Rationally designing molecularly imprinted polymer towards predetermined high selectivity by using metal as assembled pivot.

  Macromolecular bioscience 20070911

• Degradation of high-molar-mass hyaluronan by an oxidative system comprising ascorbate, Cu(II), and hydrogen peroxide: inhibitory action of antiinflammatory drugs--naproxen and acetylsalicylic acid.

  Journal of pharmaceutical and biomedical analysis 20070903

• Acute spinal cord injury changes the disposition of some, but not all drugs given intravenously.

  Spinal cord 20070901

• Naproxen versus acetaminophen for therapy of soft tissue injuries to the ankle in children.

  The Annals of pharmacotherapy 20070901

• Etoricoxib versus naproxen in patients with rheumatoid arthritis: a prospective, randomized, comparator-controlled 121-week trial.

  Current medical research and opinion 20070901

• Clinical and ultrasound assessment of the knee in children with juvenile rheumatoid arthritis.

  Indian journal of pediatrics 20070901

• [Acute migraine. Sumatriptan-naproxen combination tablets work better than a single substance].

  Medizinische Monatsschrift fur Pharmazeuten 20070901

• The influence of mobile phase demixion on thin-layer chromatographic enantioseparation of ibuprofen and naproxen.

  Journal of chromatographic science 20070901

• Clinical safety and efficacy of NG440: a novel combination of rho iso-alpha acids from hops, rosemary, and oleanolic acid for inflammatory conditions.

  Canadian journal of physiology and pharmacology 20070901

• Sensitization of central trigeminovascular neurons: blockade by intravenous naproxen infusion.

  Neuroscience 20070824

• Synthesis and pharmacological evaluation of condensed heterocyclic 6-substituted-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazole derivatives of naproxen.

  Bioorganic & medicinal chemistry letters 20070815

• Pharmacological, pharmacokinetic, and primate analgesic efficacy profile of the novel bradykinin B1 Receptor antagonist ELN441958.

  The Journal of pharmacology and experimental therapeutics 20070801

• Human pharmacology of naproxen sodium.

  The Journal of pharmacology and experimental therapeutics 20070801

• Accumulation of topical naproxen by cultured oral epithelium.

  Journal of dental research 20070801

• Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms.

  Gastroenterology 20070801

• [Developmental toxicity of naproxen].

  Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070801

• Effects of activity modification on the patients with osteoarthritis of the knee.

  Bangladesh Medical Research Council bulletin 20070801

• Opioids for chronic low-back pain.

  The Cochrane database of systematic reviews 20070718

• Evaluation of the efficacy and safety of etoricoxib compared with naproxen in two, 138-week randomised studies of patients with osteoarthritis.

  Annals of the rheumatic diseases 20070701

• Effectiveness of gabapentin in the treatment of chronic post-thoracotomy pain.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20070701

• Risk of myocardial infarction associated with selective COX-2 inhibitors: meta-analysis of randomised controlled trials.

  Pharmacoepidemiology and drug safety 20070701

• Oral naproxen but not oral paracetamol reduces the need for rescue analgesic after adenoidectomy in children.

  Acta anaesthesiologica Scandinavica 20070701

• Intercellular communication in plants: evidence for two rapidly transmitted systemic signals generated in response to electromagnetic field stimulation in tomato.

  Plant, cell & environment 20070701

• Determination of drug-serum protein interactions via fluorescence polarization measurements.

  Analytical and bioanalytical chemistry 20070701

• Effect of risk factors on complicated and uncomplicated ulcers in the TARGET lumiracoxib outcomes study.

  Gastroenterology 20070701

• Treatment of menstrual migraine: evidence-based review.

  Managed care (Langhorne, Pa.) 20070701

• Electrokinetic migration of acidic drugs across a supported liquid membrane.

  Journal of chromatography. A 20070608

• Cardiovascular outcomes in high risk patients with osteoarthritis treated with ibuprofen, naproxen or lumiracoxib.

  Annals of the rheumatic diseases 20070601

• Cyclooxygenase inhibition attenuates 3-nitropropionic acid-induced neurotoxicity in rats: possible antioxidant mechanisms.

  Fundamental & clinical pharmacology 20070601

• Effect of oppositely charged polymer and dissolution medium on swelling, erosion, and drug release from chitosan matrices.

  AAPS PharmSciTech 20070601

• [Corneal edema and systemic NSAIDs].

  Journal francais d'ophtalmologie 20070601

• Efficacy and tolerability of valdecoxib in treating the signs and symptoms of severe rheumatoid arthritis: a 12-week, multicenter, randomized, double-blind, placebo-controlled study.

  Clinical therapeutics 20070601

• The effects of AZD3582 [4-(nitroxy)butyl-(2S)-2-(6-methoxy-2-naphthyl) propanoate], and naproxen on key pathogenic steps in NSAID-enteropathy in the rat.

  Inflammopharmacology 20070601

• Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial.

  Neurology 20070522

• Micelle formation and drug release behavior of polypeptide graft copolymer and its mixture with polypeptide block copolymer.

  International journal of pharmaceutics 20070504

• In vitro evaluation of dendrimer prodrugs for oral drug delivery.

  International journal of pharmaceutics 20070504

• Effect of systemically administered naproxen sodium on clinical parameters and myeloperoxidase and elastase-like activity levels in gingival crevicular fluid.

  Journal of periodontology 20070501

• A variant of thyrotoxicosis associated with chronic thyroiditis characterized by prolonged fever, absence of anti-thyroidal antibodies, and favorable response to naproxen.

  The American journal of the medical sciences 20070501

• Naproxen sodium in short-term prophylaxis of pure menstrual migraine: pathophysiological and clinical considerations.

  Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20070501

• A comparison of four disability scales for Turkish patients with neck pain.

  Journal of rehabilitation medicine 20070501

• [Back pain and acne conglobata: SAPHO syndrome].

  Praxis 20070411

• Sumatriptan-naproxen for acute treatment of migraine: a randomized trial.

  JAMA 20070404

• Quantitative assessment of the gastrointestinal and cardiovascular risk-benefit of celecoxib compared to individual NSAIDs at the population level.

  Pharmacoepidemiology and drug safety 20070401

• Rivaroxaban (BAY 59-7939)--an oral, direct Factor Xa inhibitor--has no clinically relevant interaction with naproxen.

  British journal of clinical pharmacology 20070401

• Inhibition of cAMP-dependent protein kinase A: a novel cyclo-oxygenase-independent effect of non-steroidal anti-inflammatory drugs in adipocytes.

  Autonomic & autacoid pharmacology 20070401

• Smoking, caffeine, and nonsteroidal anti-inflammatory drugs in families with Parkinson disease.

  Archives of neurology 20070401

• Multicommuted fluorometric multiparameter sensor for simultaneous determination of naproxen and salicylic acid in biological fluids.

  Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070401

• Deterministic and probabilistic acute-based environmental risk assessment for naproxen for western Europe.

  Environmental toxicology and chemistry 20070401

• [A novel class of anti-inflammatory and analgesic drugs--NO-donating NSAIDs].

  Yao xue xue bao = Acta pharmaceutica Sinica 20070401

• Sequential injection affinity chromatography utilizing an albumin immobilized monolithic column to study drug-protein interactions.

  Journal of chromatography. A 20070309

• [By what means does the rheumatic patient with gastrointestinal risks fare best?].

  MMW Fortschritte der Medizin 20070308

• Solid molecular dispersions of poorly water-soluble drugs in poly(2-hydroxyethyl methacrylate) hydrogels.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070301

• N-Alkyl-N-alkyloxycarbonylaminomethyl (NANAOCAM) prodrugs of carboxylic acid containing drugs.

  Bioorganic & medicinal chemistry letters 20070301

• Drug permeability across a phospholipid vesicle based barrier: 3. Characterization of drug-membrane interactions and the effect of agitation on the barrier integrity and on the permeability.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070301

• Risks and benefits of COX-2 inhibitors vs non-selective NSAIDs: does their cardiovascular risk exceed their gastrointestinal benefit? A retrospective cohort study.

  Rheumatology (Oxford, England) 20070301

• Bullous amyloidosis presenting as naproxen-induced photosensitivity.

  International journal of dermatology 20070301

• In vitro and in vivo studies on HPMC-K-100 M matrices containing naproxen sodium.

  Drug delivery 20070301

• Ethyl cellulose-based solid matrix system for sustaining release of naproxen.

  Pakistan journal of biological sciences : PJBS 20070215

• The assignment of the absolute configuration of diethyl hydroxy- and aminophosphonates by 1H and 31P NMR using naproxen as a reliable chiral derivatizing agent.

  The Journal of organic chemistry 20070202

• On the calculation of the concentration dependence of drug binding to plasma proteins with multiple binding sites of different affinities: determination of the possible variation of the unbound drug fraction and calculation of the number of binding sites of the protein.

  Journal of pharmaceutical sciences 20070201

• Factors affecting the formation of eutectic solid dispersions and their dissolution behavior.

  Journal of pharmaceutical sciences 20070201

• Non-carboxylic analogues of arylpropionic acids: synthesis, anti-inflammatory activity and ulcerogenic potential.

  European journal of medicinal chemistry 20070201

• Synthesis, characterisation, and biological studies of CdTe quantum dot-naproxen conjugates.

  ChemMedChem 20070201

• A randomized, double-blind, one-week study comparing effects of a novel COX-2 inhibitor and naproxen on the gastric mucosa.

  Digestive diseases and sciences 20070201

• 12 things you should know about pain relievers. A dozen take-home messages about the pills that take the hurt away.

  Harvard health letter 20070201

• Calculation methods to perform mass balances of micropollutants in sewage treatment plants. application to pharmaceutical and personal care products (PPCPs).

  Environmental science & technology 20070201

• Nonaqueous capillary electrophoretic behavior of 2-aryl propionic acids in the presence of an achiral ionic liquid. A chemometric approach.

  Journal of chromatography. A 20070105

• A new tetrahydrated form of sodium naproxen.

  Journal of pharmaceutical sciences 20070101

• Naproxen treatment prevents periprocedural inflammatory response but not myocardial injury after percutaneous coronary intervention.

  Thrombosis research 20070101

• Chronic multifocal non-bacterial osteomyelitis in hypophosphatasia mimicking malignancy.

  BMC pediatrics 20070101

• Controlling the association of adamantyl-substituted poly{N-[tris(hydroxymethyl)methyl]acrylamide} and a beta-cyclodextrin/epichlorohydrin polymer by a small drug molecule--naproxen.

  Chemistry & biodiversity 20070101

• Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis.

  Arthritis research & therapy 20070101

• Twelve-month tolerability and safety of sumatriptan-naproxen sodium for the treatment of acute migraine.

  Mayo Clinic proceedings 20070101

• Naproxen still rules.

  DukeMedicine healthnews 20070101

• Case reports: selected dermatoses in children of color.

  Journal of drugs in dermatology : JDD 20070101

• The prevalence of postoperative pain in a cross-sectional group of patients after day-case surgery in a university hospital.

  The Clinical journal of pain 20070101

• Naproxcinod: AZD 3582, HCT 3012, naproxen nitroxybutylester, nitronaproxen, NO-naproxen.

  Drugs in R&D 20070101

• An economic model of long-term use of celecoxib in patients with osteoarthritis.

  BMC gastroenterology 20070101

• A biological rationale for the cardiotoxic effects of rofecoxib: comparative analysis with other COX-2 selective agents and NSAids.

  Sub-cellular biochemistry 20070101

• [Electroencephalographic changes in headaches under the influence of pharmaceuticals].

  Medicinski arhiv 20070101

• Anti-inflammatory and side effects of cyclooxygenase inhibitors.

  Pharmacological reports : PR 20070101

• Photochemical degradation of naproxen in the aquatic environment.

  Water science and technology : a journal of the International Association on Water Pollution Research 20070101

• Idiosyncratic toxic hepatitis secondary to single dose of naproxen.

  Acta gastro-enterologica Belgica 20070101

• Two double-blind, multicenter, randomized, placebo-controlled, single-dose studies of sumatriptan/naproxen sodium in the acute treatment of migraine: function, productivity, and satisfaction outcomes.

  MedGenMed : Medscape general medicine 20070101

• Equilibrium solubilization of lipophilic therapeutic agents by aqueous solutions of products of catalytic oxyethylation of Croda-type lanolin as model excipients of the class of non-ionic surface active agents.

  Polimery w medycynie 20070101

• Fixed drug eruption: primary site involvement on maximal points of Head's zones.

  Acta dermato-venereologica 20070101

• Methotrexate/naproxen-associated severe hepatitis in a child with juvenile idiopathic arthritis.

  Clinical and experimental rheumatology 20070101

• Protective effect of non-selective and selective COX-2-inhibitors in acute immobilization stress-induced behavioral and biochemical alterations.

  Pharmacological reports : PR 20070101

• Solubilizing and lithogenolitic properties of water solutions of non-ionic surfactants of cholesterol oxyethylenation products.

  Polimery w medycynie 20070101

• The effects of G-CSF and naproxen sodium on the serum TGF-beta1 level and fracture healing in rat tibias.

  Life sciences 20061203

• Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats.

  European journal of pharmacology 20061203

• The efficacy and safety of aceclofenac versus placebo and naproxen in women with primary dysmenorrhoea.

  European journal of obstetrics, gynecology, and reproductive biology 20061201

• Charge transfer complex studies between some non-steroidal anti-inflammatory drugs and pi-electron acceptors.

  Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061201

• In vitro assessment of drug release rates from oil depot formulations intended for intra-articular administration.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20061201

• Oral treatment with rofecoxib reduces hippocampal excitotoxic neurodegeneration.

  The Journal of pharmacology and experimental therapeutics 20061201

• Acute pancreatitis following naproxen intake.

  European journal of emergency medicine : official journal of the European Society for Emergency Medicine 20061201

• Update on the medical treatment of juvenile idiopathic arthritis.

  Current rheumatology reports 20061201

• Is any one analgesic superior for episodic tension-type headache?

  The Journal of family practice 20061201

• Do selective COX-2 inhibitors increase the risk of cerebrovascular events? A meta-analysis of randomized controlled trials.

  Journal of clinical pharmacy and therapeutics 20061201

• Binding of naproxen and amitriptyline to bovine serum albumin: biophysical aspects.

  The journal of physical chemistry. B 20061130

• Nonsteroidal anti-inflammatory drug use in ankylosing spondylitis--a population-based survey.

  Clinical rheumatology 20061101

• Effects of cyclooxygenase inhibition on the gastrointestinal tract.

  Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20061101

• Eicosanoid biosynthesis inhibitors influence mortality of Pieris brassicae larvae co-injected with fungal conidia.

  Archives of insect biochemistry and physiology 20061101

• Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysis.

  Arthritis and rheumatism 20061101

• Nonsteroidal anti-inflammatory drugs: cyclooxygenase 2 inhibitors.

  Jornal de pediatria 20061101

• New warnings about painkillers, new advice on what you can do.

  Heart advisor 20061101

• Methotrexate for ankylosing spondylitis.

  The Cochrane database of systematic reviews 20061018

• Signal enhancement in HPLC/microcoil NMR using automated column trapping.

  Analytical chemistry 20061015

• Macrocyclic chiral receptors toward enantioselective recognition of naproxen.

  Organic letters 20061012

• Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2.

  JAMA 20061004

• Amiodarone analog-dependent effects on CYP2C9-mediated metabolism and kinetic profiles.

  Drug metabolism and disposition: the biological fate of chemicals 20061001

• Permeability assessment of poorly water-soluble compounds under solubilizing conditions: the reciprocal permeability approach.

  Journal of pharmaceutical sciences 20061001

• Simultaneous effect of cyclodextrin complexation, pH, and hydrophilic polymers on naproxen solubilization.

  Journal of pharmaceutical and biomedical analysis 20060911

• Synthesis of 1-beta-O-acyl glucuronides of diclofenac, mefenamic acid and (S)-naproxen by the chemo-selective enzymatic removal of protecting groups from the corresponding methyl acetyl derivatives.

  Organic & biomolecular chemistry 20060907

• Chondroitin sulfate-based anti-inflammatory macromolecular prodrugs.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060901

• Fluorescence determination of enantiomeric composition of pharmaceuticals via use of ionic liquid that serves as both solvent and chiral selector.

  Analytical biochemistry 20060901

• Renal tubular dysgenesis with atypical histology and in-utero exposure to naproxen sodium.

  Annals of tropical paediatrics 20060901

• Overuse of over-the-counter analgesics by emergency department patients.

  Annals of emergency medicine 20060901

• Epstein-Barr virus associated Hodgkin lymphoma in a 9-year-old girl receiving long-term methotrexate therapy for juvenile idiopathic arthritis.

  Journal of pediatric hematology/oncology 20060901

• Analgesic efficacy of the cyclooxygenase-inhibiting nitric oxide donor AZD3582 in postoperative dental pain: Comparison with naproxen and rofecoxib in two randomized, double-blind, placebo-controlled studies.

  Clinical therapeutics 20060901

• [What do we know about the cardiovascular toxicity of the NSAIDs?].

  Presse medicale (Paris, France : 1983) 20060901

• [Are the NSAIDs able to compromising the cardio-preventive efficacy of aspirin?].

  Presse medicale (Paris, France : 1983) 20060901

• A teenager with fever, rash and arthritis.

  CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20060815

• [Overestimated].

  Medizinische Klinik (Munich, Germany : 1983) 20060815

• Assay of naproxen by high-performance liquid chromatography and identification of its photoproducts by LC-ESI MS.

  Biomedical chromatography : BMC 20060801

• Pharmacokinetic interactions of concomitant administration of febuxostat and NSAIDs.

  Journal of clinical pharmacology 20060801

• Sumatriptan: update and review.

  Expert opinion on pharmacotherapy 20060801

• Primary dysmenorrhea: advances in pathogenesis and management.

  Obstetrics and gynecology 20060801

• Lapses at the new England journal of medicine.

  Journal of the Royal Society of Medicine 20060801

• Implication of substrate-assisted catalysis on improving lipase activity or enantioselectivity in organic solvents.

  Biochimica et biophysica acta 20060801

• Improved anti-inflammatory properties for naproxen with cyclodextrin-grafted polysaccharides.

  Macromolecular bioscience 20060714

• Evaluation of intra-renal oxygenation during water diuresis: a time-resolved study using BOLD MRI.

  Kidney international 20060701

• Abnormal blink reflex studies in a patient with supraorbital neuralgia.

  Cephalalgia : an international journal of headache 20060701

• Development of an in vitro rat intestine segmental perfusion model to investigate permeability and predict oral fraction absorbed.

  Pharmaceutical research 20060701

• Meta-analysis: cardiovascular events associated with nonsteroidal anti-inflammatory drugs.

  The American journal of medicine 20060701

• Emergency department treatment of anaphylaxis: is epinephrine always indicated?

  Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060701

• Naproxen release from sustained release matrix system and effect of cellulose derivatives.

  Pakistan journal of pharmaceutical sciences 20060701

• Factors involved in upregulation of inducible nitric oxide synthase in rat small intestine following administration of nonsteroidal anti-inflammatory drugs.

  Digestive diseases and sciences 20060701

• Profiling urinary metabolites of naproxen by liquid chromatography-electrospray mass spectrometry.

  Journal of pharmaceutical and biomedical analysis 20060616

• Effect of naproxen on gastric acid secretion and gastric pH.

  Alimentary pharmacology & therapeutics 20060615

• Altering lipase activity and enantioselectivity in organic media using organo-soluble bases: Implication for rate-limiting proton transfer in acylation step.

  Biotechnology and bioengineering 20060605

• Greater reduction of knee than hip pain in osteoarthritis treated with naproxen, as evaluated by WOMAC and SF-36.

  Annals of the rheumatic diseases 20060601

• Correlation between in vitro and in vivo concentration-effect relationships of naproxen in rats and healthy volunteers.

  British journal of pharmacology 20060601

• Effect of oil phase lipophilicity on in vitro drug release from o/w microemulsions with low surfactant content.

  Drug development and industrial pharmacy 20060601

• Increased risk of myocardial infarction as first manifestation of ischaemic heart disease and nonselective nonsteroidal anti-inflammatory drugs.

  British journal of clinical pharmacology 20060601

• Naproxen-induced lichen planus: report of 55 cases.

  International journal of dermatology 20060601

• Treating axial manifestations in ankylosing spondylitis in the presence of peripheral arthritis.

  Nature clinical practice. Rheumatology 20060601

• The impact of low-dose aspirin on endoscopic gastric and duodenal ulcer rates in users of a non-selective non-steroidal anti-inflammatory drug or a cyclo-oxygenase-2-selective inhibitor.

  Alimentary pharmacology & therapeutics 20060515

• Evaluation of the comparative efficacy and tolerability of rofecoxib and naproxen in children and adolescents with juvenile rheumatoid arthritis: a 12-week randomized controlled clinical trial with a 52-week open-label extension.

  The Journal of rheumatology 20060501

• Microsphere-based protease assays and screening application for lethal factor and factor Xa.

  Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

• Lichenoid and granulomatous stomatitis: an entity or a non-specific inflammatory process?

  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20060501

• Accumulation of non-steroidal anti-inflammatory drugs by gingival fibroblasts.

  Journal of dental research 20060501

• Ability of practitioners to identify solid oral dosage tablets.

  American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060501

• Synthesis and anti-inflammatory activity of a series of N-substituted naproxen glycolamides: nitric oxide-donor naproxen prodrugs.

  Bioorganic & medicinal chemistry 20060415

• Comparative assessment of two indices of drug induced permeability changes in the perfused rat intestine.

  International journal of pharmaceutics 20060407

• Arthritis accompanying ileal pouchitis or undifferentiated HLA B27-related spondyloarthropathy?

  Rheumatology international 20060401

• Drug entrapment in silica microspheres through a single step sol-gel process and in vitro release behavior.

  Journal of biomedical materials research. Part B, Applied biomaterials 20060401

• Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: a comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride.

  Synapse (New York, N.Y.) 20060401

• Nitric oxide and prostacyclin pathways: an integrated mechanism that limits myocardial infarction progression in anaesthetized rats.

  Pharmacological research 20060401

• Cardiovascular risk with cyclooxygenase inhibitors: general problem with substance specific differences?

  Naunyn-Schmiedeberg's archives of pharmacology 20060401

• Chemometric determination of naproxen sodium and pseudoephedrine hydrochloride in tablets by HPLC.

  Chemical & pharmaceutical bulletin 20060401

• Effect of laparoscopic versus open gastric bypass surgery on postoperative pain and bowel function.

  Obesity surgery 20060401

• Nitric oxide and inflammation.

  Inflammation & allergy drug targets 20060401

• NO-NSAIDs: from inflammatory mediators to clinical readouts.

  Inflammation & allergy drug targets 20060401

• How high should total pain-relief score be to obviate the need for analgesic remedication in acute pain? Estimation using signal detection theory and individual-patient meta-analysis.

  Journal of clinical pharmacy and therapeutics 20060401

• Protective effect of naproxen (non-selective COX-inhibitor) or rofecoxib (selective COX-2 inhibitor) on immobilization stress-induced behavioral and biochemical alterations in mice.

  European journal of pharmacology 20060327

• Effect of glutamate receptor antagonists and antirheumatic drugs on proliferation of synoviocytes in vitro.

  European journal of pharmacology 20060327

• Naproxen-induced oxidative stress in the isolated perfused rat liver.

  Chemico-biological interactions 20060325

• Expression of concern reaffirmed.

  The New England journal of medicine 20060316

• Response to expression of concern regarding VIGOR study.

  The New England journal of medicine 20060316

• Response to expression of concern regarding VIGOR study.

  The New England journal of medicine 20060316

• Cyclodextrin-grafted polysaccharides as supramolecular carrier systems for naproxen.

  Bioorganic & medicinal chemistry letters 20060315

• Modulation of insulin-like growth factor 1 levels in human osteoarthritic subchondral bone osteoblasts.

  Bone 20060301

• Development and evaluation of an in vitro method for prediction of human drug absorption I. Assessment of artificial membrane composition.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060301

• Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301

• Celecoxib versus naproxen and diclofenac in osteoarthritis patients: SUCCESS-I Study.

  The American journal of medicine 20060301

• Dose-effect comparisons of the CINOD AZD3582 and naproxen on upper gastrointestinal tract mucosal injury in healthy subjects.

  Scandinavian journal of gastroenterology 20060301

• [Analysis of the use and adverse effects of non-steroidal anti-inflammatory drugs: a pilot study].

  Vojnosanitetski pregled 20060301

• Non-steroidal antiinflammatory drugs and the risk of acute myocardial infarction.

  Basic & clinical pharmacology & toxicology 20060301

• A multicenter, randomized, double-blind, active-comparator, placebo-controlled, parallel-group comparison of the incidence of endoscopic gastric and duodenal ulcer rates with valdecoxib or naproxen in healthy subjects aged 65 to 75 years.

  Clinical therapeutics 20060301

• Preparation of controlled release microspheres using supercritical fluid technology for delivery of anti-inflammatory drugs.

  International journal of pharmaceutics 20060203

• Synthesis, characterization and stability of dendrimer prodrugs.

  International journal of pharmaceutics 20060203

• Dense gas processing of micron-sized drug formulations incorporating hydroxypropylated and methylated beta-cyclodextrin.

  Pharmaceutical research 20060201

• Prevalence and mechanism of nonsteroidal anti-inflammatory drug-induced clinical relapse in patients with inflammatory bowel disease.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060201

• Potentiation of antinociceptive effect of NSAIDs by a specific lipooxygenase inhibitor, acetyl 11-keto-beta boswellic acid.

  Indian journal of experimental biology 20060201

• A comparison of valdecoxib and naproxen in the treatment of rheumatoid arthritis symptoms.

  Clinical therapeutics 20060201

• Multicenter, randomized, double-blind, active-controlled, parallel-group trial of the long-term (6-12 months) safety of acetaminophen in adult patients with osteoarthritis.

  Clinical therapeutics 20060201

• Application of solid-phase microextraction in the investigation of protein binding of pharmaceuticals.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060118

• Pharmacokinetic interaction of tetracycline with non-steroidal anti-inflammatory drugs via organic anion transporters in rats.

  Pharmacological research 20060101

• Bleeding colonic ulcer and eosinophilic colitis: a rare complication of nonsteroidal anti-inflammatory drugs.

  Journal of clinical gastroenterology 20060101

• Altered pharmacokinetics of zalcitabine by concurrent use of NSAIDs in rats.

  Acta pharmacologica Sinica 20060101

• The effect of single-dose naproxen on eicosanoid formation in human gastroduodenal mucosa.

  Alimentary pharmacology & therapeutics 20060101

• Cyclooxygenase-2 induction after oral surgery does not entirely account for analgesia after selective blockade of cyclooxygenase 2 in the preoperative period.

  Anesthesiology 20060101

• [A new cause of intra and extrahepatic cholangitis: the drug hypersensitivity syndrome or DRESS (Drug Rash with Eosinophilia and Systemic Symptoms)].

  Gastroenterologie clinique et biologique 20060101

• [Postoperative pain management in clinics of otolaryngology].

  Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat 20060101

• Measurement of naproxen in human plasma by chip-based immunoaffinity capillary electrophoresis.

  Biomedical chromatography : BMC 20060101

• Naproxen sodium/metoclopramide: metoclopramide/naproxen-sodium, MT 100, naproxen-sodium/metoclopramide.

  Drugs in R&D 20060101

• Nitronaproxen: AZD 3582, HCT 3012, Naproxen Nitroxybutylester, NO-Naproxen.

  Drugs in R&D 20060101

• Effective NSAID treatment indicates that hyperprostaglandinism is affecting the clinical severity of childhood hypophosphatasia.

  Orphanet journal of rare diseases 20060101

• Temporal relationship between use of NSAIDs, including selective COX-2 inhibitors, and cardiovascular risk.

  Drug safety 20060101

• Gastrointestinal complications of over-the-counter nonsteroidal antiinflammatory drugs.

  Journal of pain & palliative care pharmacotherapy 20060101

• Fever of unknown origin (FUO) caused by multiple myeloma: the diagnostic value of the Naprosyn test.

  Heart & lung : the journal of critical care 20060101

• Comparative bioavailability of two oral suspensions of naproxen sodium.

  Arzneimittel-Forschung 20060101

• Design and evaluation of a self-adhesive naproxen-loaded film prepared from a nanoparticle dispersion.

  Journal of nanoscience and nanotechnology 20060101

• Micellar solubilization of selected non-steroidal therapeutic agents by new surface-active agents of the class of the products of oxyethylation of ursodeoxycholic acid.

  Polimery w medycynie 20060101

• A comparison of the lidocaine patch 5% vs naproxen 500 mg twice daily for the relief of pain associated with carpal tunnel syndrome: a 6-week, randomized, parallel-group study.

  MedGenMed : Medscape general medicine 20060101

• Drug testing. Massive trial of Celebrex seeks to settle safety concerns.

  Science (New York, N.Y.) 20051223

• Increased susceptibility of ethanol-treated gastric mucosa to naproxen and its inhibition by DA-9601, an Artemisia asiatica extract.

  World journal of gastroenterology 20051221

• Comparison of the COX-inhibiting nitric oxide donator AZD3582 and rofecoxib in treating the signs and symptoms of Osteoarthritis of the knee.

  Arthritis and rheumatism 20051215

• Sulphation of o-desmethylnaproxen and related compounds by human cytosolic sulfotransferases.

  British journal of clinical pharmacology 20051201

• Protective effect of cyclooxygenase-2 (COX-2) inhibitors but not non-selective cyclooxygenase (COX)-inhibitors on ethanol withdrawal-induced behavioural changes.

  Addiction biology 20051201

• Risk of serious upper gastrointestinal toxicity with over-the-counter nonaspirin nonsteroidal anti-inflammatory drugs.

  Gastroenterology 20051201

• Clinical pharmacokinetics of the cyclooxygenase inhibiting nitric oxide donator (CINOD) AZD3582.

  The Journal of pharmacy and pharmacology 20051201

• [Study results of routine clinical practice. Do rheumatism patients get substandard care?].

  MMW Fortschritte der Medizin 20051124

• [Do selective COX-2 inhibitors have adverse renal and cardiovascular effects?].

  Praxis 20051123

• Efficacy of cyclo-oxygenase-2 inhibition by etoricoxib and naproxen on the axial manifestations of ankylosing spondylitis in the presence of peripheral arthritis.

  Annals of the rheumatic diseases 20051101

• Neoplastic fever: a neglected paraneoplastic syndrome.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20051101

• Neoplastic fever: all who shiver are not infected.

  Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20051101

• Prediction of CYP2C9-mediated drug-drug interactions: a comparison using data from recombinant enzymes and human hepatocytes.

  Drug metabolism and disposition: the biological fate of chemicals 20051101

• A comparison of the cyclooxygenase inhibitor-NO donors (CINOD), NMI-1182 and AZD3582, using in vitro biochemical and pharmacological methods.

  Biochemical pharmacology 20051101

• The post-operative analgesic efficacy and tolerability of lumiracoxib compared with placebo and naproxen after total knee or hip arthroplasty.

  Acta anaesthesiologica Scandinavica 20051101

• Nitric oxide-modulating agents for gastrointestinal disorders.

  Expert opinion on investigational drugs 20051101

• Risk of hospitalization with peptic ulcer disease or gastrointestinal hemorrhage associated with nabumetone, Arthrotec, diclofenac, and naproxen in a population based cohort study.

  The Journal of rheumatology 20051101

• Patterns of use and public perception of over-the-counter pain relievers: focus on nonsteroidal antiinflammatory drugs.

  The Journal of rheumatology 20051101

• Celecoxib compared with lansoprazole and naproxen to prevent gastrointestinal ulcer complications.

  The American journal of medicine 20051101

• Effects of pine needle extract on pacemaker currents in interstitial cells of Cajal from the murine small intestine.

  Molecules and cells 20051031

• A comparison of two primary care trials on tennis elbow: issues of external validity.

  Annals of the rheumatic diseases 20051001

• Coadministration of lansoprazole and naproxen does not affect the pharmacokinetic profile of methotrexate in adult patients with rheumatoid arthritis.

  Journal of clinical pharmacology 20051001

• S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.

  British journal of clinical pharmacology 20051001

• Is there an association between the use of different types of nonsteroidal antiinflammatory drugs and radiologic progression of osteoarthritis? The Rotterdam Study.

  Arthritis and rheumatism 20051001

• The lessons of Vioxx.

  The New England journal of medicine 20050929

• Simultaneous determination of naproxen, ketoprofen and phenol red in samples from rat intestinal permeability studies: HPLC method development and validation.

  Journal of pharmaceutical and biomedical analysis 20050915

• Determination of naproxen in human urine by solid-phase microextraction coupled to liquid chromatography.

  Journal of pharmaceutical and biomedical analysis 20050915

• Focused microwave-assisted extraction and LC determination of the active ingredient in naproxen-based suppositories.

  Journal of pharmaceutical and biomedical analysis 20050915

• Separation of naproxen enantiomers by supercritical/subcritical fluid chromatography.

  Journal of pharmaceutical and biomedical analysis 20050915

• Ecotoxicity of naproxen and its phototransformation products.

  The Science of the total environment 20050915

• Solubility and prediction of the heat of solution of sodium naproxen in aqueous solutions.

  Journal of pharmaceutical sciences 20050901

• Hyperkalaemia with cyclooxygenase-2 inhibition and hypoaldosteronism.

  Internal medicine journal 20050901

• Role of monocarboxylic acid transporters in the cellular uptake of NSAIDs.

  The Journal of pharmacy and pharmacology 20050901

• Sumatriptan and naproxen sodium for the acute treatment of migraine.

  Headache 20050901

• The effect of non-steroidal anti-inflammatory drugs on inflammatory cystoid macular edema.

  American journal of ophthalmology 20050901

• Effects of preoperative ibuprofen and naproxen sodium on orthodontic pain.

  The Angle orthodontist 20050901

• Effects of non-ionic surfactants on isotachophoretic separations of 2-arylpropionic acids.

  Journal of chromatography. A 20050819

• Lipopolysaccharide-induced changes in mesenteric afferent sensitivity of rat jejunum in vitro: role of prostaglandins.

  American journal of physiology. Gastrointestinal and liver physiology 20050801

• Probing for affective side effects of drugs used in geriatric practice: use of daily diaries to test for effects of metoclopramide and naproxen.

  Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050801

• Peak shape modeling by Haarhoff-Van der Linde function for the determination of correct migration times: a new insight into affinity capillary electrophoresis.

  Electrophoresis 20050801

• Report of specific cardiovascular outcomes of the ADVANTAGE trial.

  Annals of internal medicine 20050719

• Stable isotopic composition of the active pharmaceutical ingredient (API) naproxen.

  Journal of pharmaceutical and biomedical analysis 20050715

• Partially purified Carica papaya lipase: a versatile biocatalyst for the hydrolytic resolution of (R,S)-2-arylpropionic thioesters in water-saturated organic solvents.

  Biotechnology and bioengineering 20050705

• Direct gas measurements indicate that the novel cyclooxygenase inhibitor AZD3582 is an effective nitric oxide donor in vivo.

  British journal of pharmacology 20050701

• Safety of short-term administration of celecoxib in decompensated cirrhosis.

  Hepatology (Baltimore, Md.) 20050701

• The cardiovascular toxicity of selective and nonselective cyclooxygenase inhibitors: comparisons, contrasts, and aspirin confounding.

  Journal of clinical pharmacology 20050701

• Neutrophilic fixed drug eruption caused by naproxen: a real entity or a stage in the histopathologic evolution of the disease?

  Journal of the American Academy of Dermatology 20050701

• Pathways and metabolites of microbial degradation of selected acidic pharmaceutical and their occurrence in municipal wastewater treated by a membrane bioreactor.

  Water research 20050701

• Effect of naproxen, a non-selective cyclo-oxygenase inhibitor, on pentylenetetrazol-induced kindling in mice.

  Clinical and experimental pharmacology & physiology 20050701

• Improvement of the clinical outcome in Ankylosing spondylitis by balneotherapy.

  Joint, bone, spine : revue du rhumatisme 20050701

• On the incorporation of the non-steroidal anti-inflammatory naproxen into cationic O/W microemulsions.

  Colloids and surfaces. B, Biointerfaces 20050625

• A simple construction of a bile acid based dendritic light harvesting system.

  Organic letters 20050623

• The lessons of Vioxx--drug safety and sales.

  The New England journal of medicine 20050623

• Sensing of antipyretic carboxylates by simple chromogenic calix[4]pyrroles.

  Journal of the American Chemical Society 20050615

• Determination of protein-ligand binding affinity by NMR: observations from serum albumin model systems.

  Magnetic resonance in chemistry : MRC 20050601

• AZD3582 increases heme oxygenase-1 expression and antioxidant activity in vascular endothelial and gastric mucosal cells.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050601

• Occurrence of acidic pharmaceuticals in raw and treated sewages and in receiving waters.

  Water research 20050601

• Possible analgesic and anti-inflammatory interactions of aspartame with opioids and NSAIDs.

  Indian journal of experimental biology 20050601

• Photodegradation of common environmental pharmaceuticals and estrogens in river water.

  Environmental toxicology and chemistry 20050601

• Reversal of elution order for profen acid enantiomers in packed-column SFC on Chiralpak AD.

  Chirality 20050515

• Measuring the mass of an electron by LC/TOF-MS: a study of 'twin ions'.

  Analytical chemistry 20050515

• Protective effect of astaxanthin on naproxen-induced gastric antral ulceration in rats.

  European journal of pharmacology 20050502

• The effect of analgesic agents on the healing rat medial collateral ligament.

  The American journal of sports medicine 20050501

• Eicosanoids mediate the laminarin-induced nodulation response in larvae of the flesh fly, Neobellieria bullata.

  Archives of insect biochemistry and physiology 20050501

• Valdecoxib is associated with improved dyspepsia-related health compared with nonspecific NSAIDs in patients with osteoarthritis or rheumatoid arthritis.

  The American journal of gastroenterology 20050501

• Re: Efficacy of celecoxib, a COX-2-specific inhibitor, and naproxen in the management of acute ankle sprain: results of a double-blind, randomized controlled trial.

  Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine 20050501

• Renal effects of the cyclooxygenase-inhibiting nitric oxide donator AZD3582 compared with rofecoxib and naproxen during normal and low sodium intake.

  Clinical pharmacology and therapeutics 20050501

• Pre-clinical pharmacokinetics of the cyclooxygenase-inhibiting nitric oxide donor (CINOD) AZD3582.

  The Journal of pharmacy and pharmacology 20050501

• Interactions of poly(vinylpyrrolidone) with ibuprofen and naproxen: experimental and modeling studies.

  Pharmaceutical research 20050501

• Association between health-related quality of life and clinical efficacy endpoints in rheumatoid arthritis patients after four weeks treatment with anti-inflammatory agents.

  International journal of clinical pharmacology and therapeutics 20050501

• In vivo skin permeation of sodium naproxen formulated in pluronic F-127 gels: effect of Azone and Transcutol.

  Drug development and industrial pharmacy 20050501

• What to take for pain now. New warnings abound, but there are good alternatives.

  Heart advisor 20050501

• What are the effects of cyclooxygenase-2-specific inhibitors on the small bowel?

  Nature clinical practice. Gastroenterology & hepatology 20050501

• Interaction of naproxen with ionic cyclodextrins in aqueous solution and in the solid state.

  Journal of pharmaceutical and biomedical analysis 20050429

• Novel composite poly(4-vinylpyridine)/polypropylene membranes with recognition properties for (S)-naproxen.

  Journal of pharmaceutical and biomedical analysis 20050429

• Arthritis medications and cardiovascular events.

  JAMA 20050427

• Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects.

  Journal of the American College of Cardiology 20050419

• The use of anti-inflammatory analgesics in the patient with cardiovascular disease: what a pain.

  Journal of the American College of Cardiology 20050419

• Minimizing complications from nonsteroidal antiinflammatory drugs: cost-effectiveness of competing strategies in varying risk groups.

  Arthritis and rheumatism 20050415

• Cellular mechanisms of acetaminophen: role of cyclo-oxygenase.

  FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050401

• A case of toxic epidermal necrolysis with lesions mostly on sun-exposed skin.

  Photodermatology, photoimmunology & photomedicine 20050401

• Leukotriene and prostaglandin synthesis pathways in osteoarthritic synovial membranes: regulating factors for interleukin 1beta synthesis.

  The Journal of rheumatology 20050401

• Evaluation of the efficacy of etoricoxib in ankylosing spondylitis: results of a fifty-two-week, randomized, controlled study.

  Arthritis and rheumatism 20050401

• Increased risk of cardiovascular events with coxibs and NSAIDs.

  Lancet (London, England) 20050401

• AntiArthritis Therapies 2005.

  Expert opinion on investigational drugs 20050401

• Synthesis and in vitro skin permeation of naproxen conjugates with alpha-alkylamino acids.

  Current drug delivery 20050401

• A randomised, placebo controlled, comparative trial of the gastrointestinal safety and efficacy of AZD3582 versus naproxen in osteoarthritis.

  Annals of the rheumatic diseases 20050301

• Effects of celecoxib and naproxen on renal function in nonazotemic patients with cirrhosis and ascites.

  Hepatology (Baltimore, Md.) 20050301

• The withdrawal of rofecoxib.

  Pharmacoepidemiology and drug safety 20050301

• Influence of the pulpal components on human dentine permeability in vitro.

  International endodontic journal 20050301

• Effects of non-steroidal anti-inflammatory drugs on the pharmacokinetics and elimination of aciclovir in rats.

  The Journal of pharmacy and pharmacology 20050301

• Pain control during fixed orthodontic appliance therapy.

  The Angle orthodontist 20050301

• Multiple ligand binding sites on A beta(1-40) fibrils.

  Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20050301

• Lessons to learn from the COX-2 saga. Yes, FDA reforms are needed. And marketing distorts how medications are used. But one moral to the story is that all drugs have risks.

  Harvard health letter 20050301

• Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo.

  The Journal of biological chemistry 20050218

• Combined liquid and solid-surface room temperature fluorimetric determination of naproxen and salicylate in serum.

  Journal of pharmaceutical and biomedical analysis 20050207

• A case of anaphylaxis to naproxen.

  Allergy 20050201

• Chronic non-bacterial osteomyelitis in children.

  Annals of the rheumatic diseases 20050201

• Isothermal titration calorimetry method for determination of cyclodextrin complexation thermodynamics between artemisinin and naproxen under varying environmental conditions.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050201

• Sensitization of mesenteric afferents to chemical and mechanical stimuli following systemic bacterial lipopolysaccharide.

  Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20050201

• Patients exposed to rofecoxib and celecoxib have different odds of nonfatal myocardial infarction.

  Annals of internal medicine 20050201

• A randomized, double-blind clinical trial of two doses of meloxicam compared with naproxen in children with juvenile idiopathic arthritis: short- and long-term efficacy and safety results.

  Arthritis and rheumatism 20050201

• Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20050201

• Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study.

  Lancet (London, England) 20050201

• Naproxen removal from water by chlorination and biofilm processes.

  Water research 20050201

• Chiral recognition ability of an (S)-naproxen- imprinted monolith by capillary electrochromatography.

  Electrophoresis 20050201

• Restorative impact of rabeprazole on gastric mucus and mucin production impairment during naproxen administration: its potential clinical significance.

  Digestive diseases and sciences 20050201

• Ask the doctor. I am a 60-year-old man with several risk factors for heart disease. I take Aleve twice a day. Do I still need to take aspirin, or is the Aleve enough? I often take ibuprofen for my headaches or aching back. Now my doctor wants me to start taking aspirin, and she suggested that I ease up on the ibuprofen. Why?

  Harvard heart letter : from Harvard Medical School 20050201

• NSAIDs increase GM-CSF release by human synoviocytes: comparison with nitric oxide-donating derivatives.

  European journal of pharmacology 20050131

• Rofecoxib for rheumatoid arthritis.

  The Cochrane database of systematic reviews 20050125

• The Effects of cyclooxygenase-2 inhibitors and nonsteroidal anti-inflammatory therapy on 24-hour blood pressure in patients with hypertension, osteoarthritis, and type 2 diabetes mellitus.

  Archives of internal medicine 20050124

• Hydrolytic resolution of (R,S)-naproxen 2,2,2-trifluoroethyl thioester by Carica papaya lipase in water-saturated organic solvents.

  Biotechnology and bioengineering 20050105

• Solid-state characterization and dissolution properties of naproxen-arginine-hydroxypropyl-beta-cyclodextrin ternary system.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20050101

• In vitro inhibitory effects of non-steroidal antiinflammatory drugs on UDP-glucuronosyltransferase 1A1-catalysed estradiol 3beta-glucuronidation in human liver microsomes.

  Biopharmaceutics & drug disposition 20050101

• Discontinuation of Vioxx.

  Lancet (London, England) 20050101

• Discontinuation of Vioxx.

  Lancet (London, England) 20050101

• Discontinuation of Vioxx.

  Lancet (London, England) 20050101

• Recombinant human lactoferrin prevents NSAID-induced intestinal bleeding in rodents.

  The Journal of pharmacy and pharmacology 20050101

• Tracking acidic pharmaceuticals, caffeine, and triclosan through the wastewater treatment process.

  Environmental toxicology and chemistry 20050101

• Valdecoxib for treatment of primary dysmenorrhea. A randomized, double-blind comparison with placebo and naproxen.

  Journal of general internal medicine 20050101

• Monitoring of a pharmaceutical nanomilling process using grating light reflection spectroscopy.

  Applied spectroscopy 20050101

• Electrospray ionization mass spectrometry as a tool for determination of drug binding sites to human serum albumin by noncovalent interaction.

  Rapid communications in mass spectrometry : RCM 20050101

• Local steroid injections for tennis elbow: does the pain get worse before it gets better?: Results from a randomized controlled trial.

  The Clinical journal of pain 20050101

• Orbital pseudotumor in a child with juvenile rheumatoid arthritis.

  Journal of pediatric ophthalmology and strabismus 20050101

• Topical nonsteroidal anti-inflammatory drugs in uncomplicated cataract surgery: effect of sodium naproxen.

  European journal of ophthalmology 20050101

• NMI-1182, a gastro-protective cyclo-oxygenase-inhibiting nitric oxide donor.

  Inflammopharmacology 20050101

• The murky waters of the coxibs: a review of the current state of play.

  Inflammopharmacology 20050101

• Competitive binding of ibuprofen and naproxen to bovine serum albumin : modified form of drug-drug displacement interaction at the binding site.

  Pakistan journal of pharmaceutical sciences 20050101

• Application of thin-layer chromatography to investigate oscillatory instability of the selected profen enantiomers in dichloromethane.

  Journal of chromatographic science 20050101

• Selected Rofams as a micellar solubilizers for diclofenac and naproxen in the environment of the standard vehicle for eye drops.

  Polimery w medycynie 20050101

• Lysine clonixinate vs naproxen sodium for the acute treatment of migraine: a double-blind, randomized, crossover study.

  MedGenMed : Medscape general medicine 20050101

• A new molecularly imprinted polymer for the selective extraction of naproxen from urine samples by solid-phase extraction.

  Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225

• Nitric oxide (NO)-releasing naproxen (HCT-3012 [(S)-6-methoxy-alpha-methyl-2-naphthaleneacetic Acid 4-(nitrooxy)butyl ester]) interactions with aspirin in gastric mucosa of arthritic rats reveal a role for aspirin-triggered lipoxin, prostaglandins, and NO in gastric protection.

  The Journal of pharmacology and experimental therapeutics 20041201

• Sulfone COX-2 inhibitors increase susceptibility of human LDL and plasma to oxidative modification: comparison to sulfonamide COX-2 inhibitors and NSAIDs.

  Atherosclerosis 20041201

• The effects of naproxen sodium on specific parameters of L-strain cells over guided bone regeneration barrier materials.

  Clinical oral implants research 20041201

• Nanoparticle based systemic gene therapy for lung cancer: molecular mechanisms and strategies to suppress nanoparticle-mediated inflammatory response.

  Technology in cancer research & treatment 20041201

• Risk of cardiovascular events and rofecoxib: cumulative meta-analysis.

  Lancet (London, England) 20041201

• A randomized open label study of pain medications (naproxen, acetaminophen and ibuprofen) for controlling side effects during initiation of IFN beta-1a therapy and during its ongoing use for relapsing-remitting multiple sclerosis.

  Multiple sclerosis (Houndmills, Basingstoke, England) 20041201

• Nonprescription dental pain relief.

  Dentistry today 20041201

• A presumptive case of toxocariasis associated with eosinophilic pleural effusion: case report and literature review.

  The American journal of tropical medicine and hygiene 20041201

• Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract.

  Biochimica et biophysica acta 20041118

• Calculation of cyclodextrin binding affinities: energy, entropy, and implications for drug design.

  Biophysical journal 20041101

• Immunosuppressants, infection, and inflammation.

  Clinical immunology (Orlando, Fla.) 20041101

• Risks of clinically significant upper gastrointestinal events with etodolac and naproxen: a historical cohort analysis.

  Gastroenterology 20041101

• Evidence in practice--number 3: Cox 2 inhibitors.

  The British journal of general practice : the journal of the Royal College of General Practitioners 20041101

• Development and characterization of a scalable controlled precipitation process to enhance the dissolution of poorly water-soluble drugs.

  Pharmaceutical research 20041101

• Efficacy, safety and tolerability of lumiracoxib in patients with rheumatoid arthritis.

  International journal of clinical practice 20041101

• Effect of binary and ternary polyvinylpyrrolidone and/or hydroxypropyl-beta-cyclodextrin complexes on the photochemical and photosensitizing properties of Naproxen.

  Journal of photochemistry and photobiology. B, Biology 20041025

• Coxibs and cardiovascular disease.

  The New England journal of medicine 20041021

• Multiple comparisons with a control in families with both one-sided and two-sided hypotheses.

  Statistics in medicine 20041015

• Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion.

  Muscle & nerve 20041001

• Postoperative naproxen after coronary artery bypass surgery: a double-blind randomized controlled trial.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20041001

• Determination of some acidic drugs in surface and sewage treatment plant waters by capillary electrophoresis-electrospray ionization-mass spectrometry.

  Electrophoresis 20041001

• Differential effects of naproxen and rofecoxib on the development of hypersensitivity following nerve injury in rats.

  Pharmacology, biochemistry, and behavior 20041001

• Nanosizing drug particles in supercritical fluid processing.

  Journal of the American Chemical Society 20040908

• Comparison of serum nitric oxide levels in active juvenile rheumatoid arthritis with those of patients in remission.

  Rheumatology international 20040901

• An intravitreal biodegradable sustained release naproxen and 5-fluorouracil system for the treatment of experimental post-traumatic proliferative vitreoretinopathy.

  The British journal of ophthalmology 20040901

• Treatment of painful temporomandibular joints with a cyclooxygenase-2 inhibitor: a randomized placebo-controlled comparison of celecoxib to naproxen.

  Pain 20040901

• Cost-effectiveness of treatment strategies for osteoarthritis of the knee in Taiwan.

  The Journal of rheumatology 20040901

• The flow-cytometric determination of basophil activation induced by aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) is useful for in vitro diagnosis of the NSAID hypersensitivity syndrome.

  Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040901

• [Nummular headache: case report].

  Arquivos de neuro-psiquiatria 20040901

• The nitric oxide-releasing naproxen derivative displays cardioprotection in perfused rabbit heart submitted to ischemia-reperfusion.

  The Journal of pharmacology and experimental therapeutics 20040801

• Presentation and treatment of complex regional pain syndrome type 1 in a 3 year old.

  Anesthesiology 20040801

• Celecoxib effectively treats patients with acute shoulder tendinitis/bursitis.

  The Journal of rheumatology 20040801

• Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), reduction in ulcer complications: randomised controlled trial.

  Lancet (London, England) 20040801

• Comparison of lumiracoxib with naproxen and ibuprofen in the Therapeutic Arthritis Research and Gastrointestinal Event Trial (TARGET), cardiovascular outcomes: randomised controlled trial.

  Lancet (London, England) 20040801

• Risk of serious upper gastrointestinal and cardiovascular thromboembolic complications with meloxicam.

  The American journal of medicine 20040715

• Drug carrier systems based on water-soluble cationic beta-cyclodextrin polymers.

  International journal of pharmaceutics 20040708

• Effect of anti-inflammatories on Pluronic F127: micellar assembly, gelation and partitioning.

  International journal of pharmaceutics 20040708

• Chromatographic behaviour of naproxen-cyclodextrin complexes stationary phase C8 alkyl chain as competitor for the drug release from cyclodextrin cavity.

  Journal of chromatography. A 20040702

• Acute phase response in patients undergoing lumbar spinal surgery: modulation by perioperative treatment with naproxen and famotidine.

  European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20040701

• Effect of COX-1/COX-2 inhibition versus selective COX-2 inhibition on coronary vasodilator responses to arachidonic acid and acetylcholine.

  Pharmacology 20040701

• Bilateral cleft lip and palate, hypertelorism and hypoplastic toes.

  Clinical dysmorphology 20040701

• Therapeutic arthritis research and gastrointestinal event trial of lumiracoxib - study design and patient demographics.

  Alimentary pharmacology & therapeutics 20040701

• Comparison of the analgesic efficacy and safety of nonprescription doses of naproxen sodium and Ibuprofen in the treatment of osteoarthritis of the knee.

  The Journal of rheumatology 20040701

• Dissolution characteristics of megaloporous tablets prepared with two kinds of matrix granules.

  Farmaco (Societa chimica italiana : 1989) 20040701

• Nanosuspensions: a promising drug delivery strategy.

  The Journal of pharmacy and pharmacology 20040701

• Topical provocation in fixed drug eruption due to metamizol and naproxen.

  Clinical and experimental dermatology 20040701

• Naproxen-induced generalized bullous fixed drug eruption.

  The British journal of dermatology 20040701

• Efficacy of celecoxib, a COX-2-specific inhibitor, and naproxen in the management of acute ankle sprain: results of a double-blind, randomized controlled trial.

  Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine 20040701

• Isobolographic analysis of interaction between cyclooxygenase inhibitors and tramadol in acetic acid-induced writhing in mice.

  Progress in neuro-psychopharmacology & biological psychiatry 20040701

• [Extra-thermodynamic properties of 2-arylpropionic acids on a chiral-AGP column by high performance liquid chromatography].

  Se pu = Chinese journal of chromatography 20040701

• Nonsteroidal antiinflammatory drugs and the risk of myocardial infarction in the general population.

  Circulation 20040622

• Tolerability of rofecoxib versus naproxen.

  Annals of internal medicine 20040615

• Tolerability of rofecoxib versus naproxen.

  Annals of internal medicine 20040615

• Tolerability of rofecoxib versus naproxen.

  Annals of internal medicine 20040615

• Over-the-counter pain reliever and aspirin use within a sample of long-term cyclooxygenase 2 users.

  Archives of internal medicine 20040614

• Naproxen reduces excitotoxic neurodegeneration in vivo with an extended therapeutic window.

  The Journal of pharmacology and experimental therapeutics 20040601

• Chiral recognition of zinc(II) ion complexes composed of bicyclo[3.3.0] octane-2,6-diol and s-naproxen probed by collisional-induced dissociation.

  Journal of the American Society for Mass Spectrometry 20040601

• Fish oil supplementation in F1 generation associated with naproxen, clenbuterol, and insulin administration reduce tumor growth and cachexia in Walker 256 tumor-bearing rats.

  The Journal of nutritional biochemistry 20040601

• Migraine headache.

  Clinical evidence 20040601

• Effect of binary and ternary polyethyleneglycol and/or beta-cyclodextrin complexes on the photochemical and photosensitizing properties of Naproxen.

  Journal of photochemistry and photobiology. B, Biology 20040527

• Differential activation of CYP2C9 variants by dapsone.

  Biochemical pharmacology 20040515

• Effects of rofecoxib and naproxen on life expectancy among patients with rheumatoid arthritis: a decision analysis.

  The American journal of medicine 20040501

• A population based historical cohort study of the mortality associated with nabumetone, Arthrotec, diclofenac, and naproxen.

  The Journal of rheumatology 20040501

• Another patient with chromosome 18 deletion syndrome and juvenile rheumatoid arthritis.

  The Journal of rheumatology 20040501

• Spectroscopic behavior of copper complexes of nonsteroidal anti-inflammatory drugs.

  Biopolymers 20040501

• Interspecies differences in the nephrotoxic response to cyclooxygenase inhibition.

  Drug and chemical toxicology 20040501

• Synthesis of precursor of anti-inflammatory agents by using highly reactive zinc.

  The Medical journal of Malaysia 20040501

• [Selective cox-2 inhibitors. Better tolerance than NSAID plus antacid].

  MMW Fortschritte der Medizin 20040408

• Assessment of arginine 97 and lysine 72 as determinants of substrate specificity in cytochrome P450 2C9 (CYP2C9).

  Drug metabolism and disposition: the biological fate of chemicals 20040401

• Assessment of visual analog versus categorical scale for measurement of osteoarthritis pain.

  Journal of clinical pharmacology 20040401

• A randomized, controlled comparison of ibuprofen at the maximal over-the-counter dose compared with prescription-dose celecoxib on upper gastrointestinal mucosal injury.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20040401

• The gastrointestinal tolerability of the LOX/COX inhibitor, licofelone, is similar to placebo and superior to naproxen therapy in healthy volunteers: results from a randomized, controlled trial.

  The American journal of gastroenterology 20040401

• [The effects of application of rectal naproxen on postoperative analgesia, sedation and morphine use in heart surgery operations].

  Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology 20040401

• Clinical pharmacology of platelet, monocyte, and vascular cyclooxygenase inhibition by naproxen and low-dose aspirin in healthy subjects.

  Circulation 20040330

• [Coxib instead of NSAID plus gastric acid inhibitor. Protection for the small intestine].

  MMW Fortschritte der Medizin 20040325

• Thermodynamics of solutions III: comparison of the solvation of (+)-naproxen with other NSAIDs.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20040301

• Influence of chitosan and its glutamate and hydrochloride salts on naproxen dissolution rate and permeation across Caco-2 cells.

  International journal of pharmaceutics 20040301

• [New evaluation by the EU approval committee. Benefits of cox-2 inhibitors outweigh possible risks (interview by Dr. Thomas Meissner)].

  MMW Fortschritte der Medizin 20040226

• Nonsteroidal anti-Inflammatory drugs and cardiovascular risk.

  Journal of the American College of Cardiology 20040218

• Antitumoral properties of two new vanadyl(IV) complexes in osteoblasts in culture: role of apoptosis and oxidative stress.

  Cancer chemotherapy and pharmacology 20040201

• Anesthetic effect of intrauterine lidocaine plus naproxen sodium in endometrial biopsy.

  Obstetrics and gynecology 20040201

• A common pathway of nitric oxide release from AZD3582 and glyceryl trinitrate.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040201

• Application of capillary electrophoresis with different sample stacking strategies for the determination of a group of nonsteroidal anti-inflammatory drugs in the low microg x L(-1) concentration range.

  Electrophoresis 20040201

• Longer use of COX-2-specific inhibitors compared to nonspecific nonsteroidal antiinflammatory drugs: a longitudinal study of 3639 patients in community practice.

  The Journal of rheumatology 20040201

• Naproxen affects Ca(2+) fluxes in mitochondria, microsomes and plasma membrane vesicles.

  Chemico-biological interactions 20040115

• Pharmacological characterisation of a rat model of incisional pain.

  British journal of pharmacology 20040101

• Potential interaction between acenocoumarol and diclofenac, naproxen and ibuprofen and role of CYP2C9 genotype.

  Thrombosis and haemostasis 20040101

• Comparison of the effect of chitosan and polyvinylpyrrolidone on dissolution properties and analgesic effect of naproxen.

  European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20040101

• Chiral separation by HPLC with pirkle-type chiral stationary phases.

  Methods in molecular biology (Clifton, N.J.) 20040101

• Synthesis, characterization and antiinflammatory-analgesic properties of 6-(alpha-amino-4-chlorobenzyl)thiazolo [3,2-b]-1,2,4-triazol-5-ols.

  Arzneimittel-Forschung 20040101

• Analgesic efficacy and safety of nonprescription doses of naproxen sodium compared with acetaminophen in the treatment of osteoarthritis of the knee.

  American journal of therapeutics 20040101

• Pharmaceutical-grade albumin: impaired drug-binding capacity in vitro.

  BMC clinical pharmacology 20040101

• A randomized, double-blind, parallel-group study comparing the analgesic effect of etoricoxib to placebo, naproxen sodium, and acetaminophen with codeine using the dental impaction pain model.

  The Clinical journal of pain 20040101

• Update on nonprescription pain relievers for dental pain.

  General dentistry 20040101

• A 4-1/2 year-old with a swollen knee.

  Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & Practitioners 20040101

• A two-year study of chondroitin sulfate in erosive osteoarthritis of the hands: behavior of erosions, osteophytes, pain and hand dysfunction.

  Drugs under experimental and clinical research 20040101

• Effects of nonsteroidal anti-inflammatory drugs on bone formation and soft-tissue healing.

  The Journal of the American Academy of Orthopaedic Surgeons 20040101

• Drug delivery devices based on mesoporous silicate.

  Drug delivery 20040101

• Methotrexate for ankylosing spondylitis.

  The Cochrane database of systematic reviews 20040101

• Comparative antiplatelet activity of COX1 NSAIDS versus aspirin, encompassing regimen simplification and gastroprotection: a call for a controlled study.

  Reumatismo 20040101

• Effect of naproxen on tail fin regeneration in teleost.

  Journal of submicroscopic cytology and pathology 20040101

• Delayed-release lansoprazole plus naproxen.

  Drugs 20040101

• Single dose oral naproxen and naproxen sodium for acute postoperative pain.

  The Cochrane database of systematic reviews 20040101

• [Severe toxic liver failure after acute poisoning with paracetamol, ferrous sulphate and naproxen].

  Przeglad lekarski 20040101

• In vitro effects of selective and non-selective nonsteroidal anti-inflammatory drugs on the frequency of sister chromatid exchanges.

  Drugs in R&D 20040101

• Biowaivers for oral immediate-release products: implications of linear pharmacokinetics.

  Clinical pharmacokinetics 20040101

• Characterization of the chick carrageenan response.

  Brain research 20031224

• Use of stable emulsion to improve stability, activity, and enantioselectivity of lipase immobilized in a membrane reactor.

  Biotechnology and bioengineering 20031220

• Specific site involvement in fixed drug eruption.

  Journal of the American Academy of Dermatology 20031201

• Dysmenorrhea treatment with a single daily dose of rofecoxib.

  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20031201

• [Clinical pharmacology of the selective COX-2 inhibitors].

  Der Orthopade 20031201

• Safety of cyclooxygenase 2 inhibitors and increased leukotriene synthesis in chronic idiopathic urticaria with sensitivity to nonsteroidal anti-inflammatory drugs.

  Archives of dermatology 20031201

• Incidence of outpatient physician claims for upper gastrointestinal symptoms among new users of celecoxib, ibuprofen, and naproxen in an insured population in the United States.

  The American journal of gastroenterology 20031201

• Migraine headache.

  Clinical evidence 20031201

• [Management of postoperative inflammatory response and pain with nimesulide after cardiac surgery].

  Orvosi hetilap 20031130

• Naproxen, clenbuterol and insulin administration ameliorates cancer cachexia and reduce tumor growth in Walker 256 tumor-bearing rats.

  Cancer letters 20031125

• Gastrointestinal safety of AZD3582, a cyclooxygenase inhibiting nitric oxide donator: proof of concept study in humans.

  Gut 20031101

• Maternal drug use and infant cleft lip/palate with special reference to corticoids.

  The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association 20031101

• Lack of value of the naproxen test in the differential diagnosis of prolonged febrile illnesses.

  The American journal of medicine 20031101

• Pseudoporphyria secondary to non-steroidal anti-inflammatory drugs.

  Archives of disease in childhood 20031101

• [Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs].

  Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20031101

• A water-insoluble drug monolithic osmotic tablet system utilizing gum arabic as an osmotic, suspending and expanding agent.

  Journal of controlled release : official journal of the Controlled Release Society 20031030

• Ternary naproxen: beta-cyclodextrin:polyethylene glycol complex formation.

  International journal of pharmaceutics 20031020

• [Pain therapy in rheumatism. After 65 years of age coxibs are the best choice].

  MMW Fortschritte der Medizin 20031016

• Stimulation of proteinase-activated receptor 2 excites jejunal afferent nerves in anaesthetised rats.

  The Journal of physiology 20031015

• Gastrointestinal tolerability and effectiveness of rofecoxib versus naproxen in the treatment of osteoarthritis: a randomized, controlled trial.

  Annals of internal medicine 20031007

• Summaries for patients. Gastrointestinal side effects of rofecoxib and naproxen.

  Annals of internal medicine 20031007

• Lower gastrointestinal complications of nonsteroidal anti-inflammatory drugs.

  Current gastroenterology reports 20031001

• A comparative study of the effect of rofecoxib (a COX 2 inhibitor) and naproxen sodium on analgesic requirements after abdominal hysterectomy.

  Archives of gynecology and obstetrics 20031001

• Facilitation of iontophoretic drug delivery through intact and caries-affected dentine.

  International endodontic journal 20031001

• Effect of transdermal glyceryl trinitrate and anti-inflammatory gel in infusion phlebitis.

  ANZ journal of surgery 20031001

• Selective COX-2 inhibition and cardiovascular effects: a review of the rofecoxib development program.

  American heart journal 20031001

• Persistence with COX-2 inhibitors in managed care: an analysis of claims data.

  Managed care interface 20031001

• Effect of NSAIDs on risk of Alzheimer's disease: confounding factors were not discussed.

  BMJ (Clinical research ed.) 20030927

• Polyamines reverse non-steroidal anti-inflammatory drug-induced toxicity in human colorectal cancer cells.

  The Biochemical journal 20030901

• Effects of naratriptan versus naproxen on daily functioning in the acute treatment of migraine: a randomized, double-blind, double-dummy, crossover study.

  Headache 20030901

• NSAIDs and Alzheimer's disease: how far to generalise from trials?

  The Lancet. Neurology 20030901

• Gastroduodenal tolerability of lumiracoxib vs placebo and naproxen: a pilot endoscopic study in healthy male subjects.

  Alimentary pharmacology & therapeutics 20030901

• Complexation trends and binding constants between dextrin oligomers and small molecules as measured through affinity capillary electrophoresis.

  Electrophoresis 20030901

• Naproxen as an alternative to aspirin for the treatment of arthritis of rheumatic fever: a randomized trial.

  The Journal of pediatrics 20030901

• HPLC determination of naproxen in plasma.

  Die Pharmazie 20030901

• Inflammation 2003-Sixth World Congress. Nitric oxide and IBD. 2-6 August 2003, Vancouver, Canada.

  IDrugs : the investigational drugs journal 20030901

• Simultaneous determination of naproxen and related compounds by HPLC using porous graphitic carbon column.

  Journal of pharmaceutical and biomedical analysis 20030808

• [Selective COX 2 inhibitor rofecoxib. To 'defy' the pain].

  MMW Fortschritte der Medizin 20030807

• Renal papillary necrosis induced by naproxen.

  Pediatric nephrology (Berlin, Germany) 20030801

• Pass the tablet please.

  Alternative medicine review : a journal of clinical therapeutic 20030801

• Naproxen 500 mg bid versus acetaminophen 1000 mg qid: effect on swelling and other acute postoperative events after bilateral third molar surgery.

  Journal of clinical pharmacology 20030801

• Zinc-naproxen complex: synthesis, physicochemical and biological evaluation.

  International journal of pharmaceutics 20030724

• Ternary systems of naproxen with hydroxypropyl-beta-cyclodextrin and aminoacids.

  International journal of pharmaceutics 20030724

• A comparison of the upper gastrointestinal mucosal effects of valdecoxib, naproxen and placebo in healthy elderly subjects.

  Alimentary pharmacology & therapeutics 20030701

• The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy.

  Prostaglandins & other lipid mediators 20030701

• Naproxen's interaction with aspirin may affect its cardioprotective effect.

  Archives of internal medicine 20030609

• [Progress in therapy of rheumatism. New coxib works especially fast].

  MMW Fortschritte der Medizin 20030605

• Effects of rofecoxib or naproxen vs placebo on Alzheimer disease progression: a randomized controlled trial.

  JAMA 20030604

• Effects of cyclooxygenases inhibitors on vasoactive prostanoids and thrombin generation at the site of microvascular injury in healthy men.

  Arteriosclerosis, thrombosis, and vascular biology 20030601

• Incidence of gastroduodenal ulcers in patients with rheumatoid arthritis after 12 weeks of rofecoxib, naproxen, or placebo: a multicentre, randomised, double blind study.

  Gut 20030601

• Effects of antiinflammatory drugs on arthritic cartilage: a high-frequency quantitative ultrasound study in rats.

  Arthritis and rheumatism 20030601

• NO-naproxen (AstraZeneca).

  IDrugs : the investigational drugs journal 20030601

• Characterization of etoricoxib, a novel, selective COX-2 inhibitor.

  Journal of clinical pharmacology 20030601

• Rofecoxib in rheumatoid arthritis: new indication. No better that other NSAIDS.

  Prescrire international 20030601

• Microbial transformations of S-naproxen by Aspergillus niger ATCC 9142.

  Die Pharmazie 20030601

• Sulindac sulfide is a noncompetitive gamma-secretase inhibitor that preferentially reduces Abeta 42 generation.

  The Journal of biological chemistry 20030516

• NSAIDs and hypertension.

  Archives of internal medicine 20030512

• Development and characterization of naproxen-chitosan solid systems with improved drug dissolution properties.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030501

• Juvenile chronic arthritis in a monozygotic twin couple.

  Rheumatology international 20030501

• Microbial transformation of naproxen by Cunninghamella species.

  Acta pharmacologica Sinica 20030501

• Identification of coenzyme A-related tolmetin metabolites in rats: relationship with reactive drug metabolites.

  Xenobiotica; the fate of foreign compounds in biological systems 20030501

• NO-NSAIDs and cancer: promising novel agents.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20030501

• Nitric oxide-releasing mesalamine: potential utility for treatment of inflammatory bowel disease.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20030501

• ESR detection and dosimetric properties of irradiated naproxen sodium.

  International journal of pharmaceutics 20030414

• Development of a HPLC method for the determination of cyclosporin-A in rat blood and plasma using naproxen as an internal standard.

  Journal of pharmaceutical and biomedical analysis 20030410

• Pharmaco-toxicological study of diterpenoids.

  Bioorganic & medicinal chemistry 20030403

• Unilateral presentation of a large epidural hematoma.

  Anesthesiology 20030401

• Permeation of naproxen from saturated solutions and commercial formulations through synthetic membranes.

  Drug development and industrial pharmacy 20030401

• Release and skin permeation studies of Naproxen from hydrophillic gels and effect of terpenes as enhancers on its skin permeation.

  Bollettino chimico farmaceutico 20030401

• Use of a sample translation technique to minimize adverse effects of laser irradiation in surface-enhanced Raman spectrometry.

  Applied spectroscopy 20030401

• Effect of PVP K-25 on the formation of the naproxen:beta-ciclodextrin complex.

  International journal of pharmaceutics 20030306

• Laparoscopic presacral neurolysis for endometriosis-related pelvic pain.

  Human reproduction (Oxford, England) 20030301

• A comparative study of electroporation and iontophoresis for percutaneous penetration of naproxen.

  Die Pharmazie 20030301

• Effect of immobilization site and membrane materials on multiphasic enantiocatalytic enzyme membrane reactors.

  Annals of the New York Academy of Sciences 20030301

• Lipase-catalyzed enantioselective esterification of (S)-naproxen hydroxyalkyl ester in organic media.

  Biotechnology letters 20030301

• Effect of selective cyclooxygenase 2 inhibitors and naproxen on short-term risk of acute myocardial infarction in the elderly.

  Archives of internal medicine 20030224

• Serious lower gastrointestinal clinical events with nonselective NSAID or coxib use.

  Gastroenterology 20030201

• Comparison of effects of phonophoresis and iontophoresis of naproxen in the treatment of lateral epicondylitis.

  Clinical rehabilitation 20030201

• Prodrugs and mutual prodrugs: synthesis of some new pyrazolone and oxadiazole analogues of a few non-steroidal anti-inflammatory drugs.

  Die Pharmazie 20030201

• Characterization of the in vitro anti-inflammatory activity of AL-5898 and related benzopyranyl esters and amides.

  Inflammation 20030201

• Identification of the amino acids of human serum albumin involved in the reaction with the naproxen acyl coenzyme A thioester using liquid chromatography combined with fluorescence and mass spectrometric detection.

  Analytical biochemistry 20030115

• A compaction process to enhance dissolution of poorly water-soluble drugs using hydroxypropyl methylcellulose.

  International journal of pharmaceutics 20030102

• Chitinosan-drug complexes: effect of electrolyte on naproxen release in vitro.

  International journal of pharmaceutics 20030102

• American pain society pain questionnaire and other pain measures in the assessment of osteoarthritis pain: a pooled analysis of three celecoxib pivotal studies.

  American journal of therapeutics 20030101

• MT 100.

  Drugs in R&D 20030101

• Effects of selective cyclooxygenase-2 inhibition on gingival tissue levels of prostaglandin E2 and prostaglandin F2alpha and clinical parameters of chronic periodontitis.

  Journal of periodontology 20030101

• COX-2 selective non-steroidal anti-inflammatory drugs and cardiovascular disease.

  Pharmacoepidemiology and drug safety 20030101

• In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-[6-[(2-[(18)F]fluoroethyl)(methyl)amino]-2-naphthyl]ethylidene)malononitrile.

  Neuroscience 20030101

• Product ion scanning using a Q-q-Q linear ion trap (Q TRAP) mass spectrometer.

  Rapid communications in mass spectrometry : RCM 20030101

• Celecoxib is as efficacious as naproxen in the management of acute shoulder pain.

  The Journal of international medical research 20030101

• Analgesic efficacy of etoricoxib in primary dysmenorrhea: results of a randomized, controlled trial.

  Gynecologic and obstetric investigation 20030101

• Strategic selection of hyperthermophilic esterases for resolution of 2-arylpropionic esters.

  Biotechnology progress 20030101

• An evidence-based approach to studies of gastrointestinal therapies.

  Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20030101

• Formulation and roentgenographic studies of naproxen-pectin-based matrix tablets for colon drug delivery.

  The Yale journal of biology and medicine 20030101

• The relationship between oxidative metabolism and lipid peroxidation in rat liver microsomes.

  Research communications in molecular pathology and pharmacology 20030101

• Lack of cardioprotective effect of naproxen.

  Archives of internal medicine 20021201

• Recurrent blisters on the hands and face.

  Archives of dermatology 20021201

• Assessment of solid-state interactions of naproxen with amorphous cyclodextrin derivatives by DSC.

  Journal of pharmaceutical and biomedical analysis 20021107

• Activation of CYP2C9-mediated metabolism by a series of dapsone analogs: kinetics and structural requirements.

  Drug metabolism and disposition: the biological fate of chemicals 20021101

• Biological and metabolic study of naproxen-propyphenazone mutual prodrug.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20021101

• Gabapentin and pregabalin can interact synergistically with naproxen to produce antihyperalgesia.

  Anesthesiology 20021101

• Efficacy and safety of acetaminophen and naproxen in the treatment of tension-type headache. A randomized, double-blind, placebo-controlled trial.

  Cephalalgia : an international journal of headache 20021101

• COX-2 selective NSAID decreases bone ingrowth in vivo.

  Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20021101

• Interaction of ochratoxin A with human serum albumin. Binding sites localized by competitive interactions with the native protein and its recombinant fragments.

  Chemico-biological interactions 20021020

• COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease.

  Lancet (London, England) 20021005

• Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells.

  Cancer chemotherapy and pharmacology 20021001

• Stratifying the risk of NSAID-related upper gastrointestinal clinical events: results of a double-blind outcomes study in patients with rheumatoid arthritis.

  Gastroenterology 20021001

• A 52-year-old man with sudden onset of a facial rash.

  Cleveland Clinic journal of medicine 20021001

• First- and second-order multivariate calibration applied to biological samples: determination of anti-inflammatories in serum and urine.

  Analytical and bioanalytical chemistry 20021001

• [Adverse effects of NSAID are insidious. No pain--despite life threatening gastric hemorrhage].

  MMW Fortschritte der Medizin 20020912

• Kinetics of the radicals induced in gamma-irradiated naproxen sodium and apranax. Applicability of ESR technique to monitor radiosterilization of naproxen sodium-containing drugs.

  International journal of pharmaceutics 20020905

• A randomized controlled trial examining the effect of naproxen on analgesia during the second day after cesarean delivery.

  Anesthesia and analgesia 20020901

• Efficacy and safety of valdecoxib in treating the signs and symptoms of rheumatoid arthritis: a randomized, controlled comparison with placebo and naproxen.

  Rheumatology (Oxford, England) 20020901

• Antimicrobial action of Nitens mouthwash (cetyltrimethylammonium naproxenate) on multiple isolates of pharyngeal microbes: a controlled study against chlorhexidine, benzydamine, hexetidine, amoxicillin, amoxicillin-clavulanate, clarithromycin, and cefaclor.

  Chemotherapy 20020901

• Bioactive phenolic derivatives from Acaena splendens methanol extract.

  Phytotherapy research : PTR 20020901

• Comparison of the efficacy and safety of nonprescription doses of naproxen and naproxen sodium with ibuprofen, acetaminophen, and placebo in the treatment of primary dysmenorrhea: a pooled analysis of five studies.

  Clinical therapeutics 20020901

• NSAIDS for prevention? Protecting the brain while killing pain?

  Science (New York, N.Y.) 20020823

• Characterization of physicochemical properties of naproxen systems with amorphous beta-cyclodextrin-epichlorohydrin polymers.

  Journal of pharmaceutical and biomedical analysis 20020801

• Valdecoxib, a cyclooxygenase-2-specific inhibitor, is effective in treating primary dysmenorrhea.

  Obstetrics and gynecology 20020801

• Another selective COX-2 inhibitor: more questions than answers?

  The Journal of rheumatology 20020801

• A randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis.

  The Journal of rheumatology 20020801

• Synthesis and properties of a naproxen polymeric prodrug.

  The Journal of pharmacy and pharmacology 20020801

• Ask the doctor. I have atherosclerosis in the arteries of my heart and neck, and my doctors want me to take aspirin. I also have arthritis and take Naprosyn for it every day. I have heard that Naprosyn can prevent blood clots, just like aspirin does. Can I just take Naprosyn, or do I still need to take aspirin, too, to protect my heart and brain from blood clots?

  Harvard heart letter : from Harvard Medical School 20020801

• Oligoethylene ester derivatives of ketoprofen, naproxen and diclofenac as oral prodrugs: a pharmacological evaluation.

  Die Pharmazie 20020801

• Differential effects of nonsteroidal antiinflammatory drugs on the IL-1 altered expression of plasminogen activators and plasminogen activator inhibitor-1 by articular chondrocytes.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020801

• Investigation of lipase-catalysed hydrolysis of naproxen methyl ester: use of NMR spectroscopy methods to study substrate-enzyme interaction.

  Bioorganic chemistry 20020801

• NO-donors (VII [1]): synthesis and cyclooxygenase inhibitory properties of N-and S-nitrooxypivaloyl-cysteine derivatives of naproxen -- a novel type of NO-NSAID.

  Archiv der Pharmazie 20020801

• Severe neutropenia due to naproxen therapy in rheumatoid arthritis: a case report and review of literature.

  The Netherlands journal of medicine 20020801

• Integration of reactive membrane extraction with lipase-hydrolysis dynamic kinetic resolution of naproxen 2,2,2-trifluoroethyl thioester in isooctane.

  Biotechnology and bioengineering 20020720

• Modulatory role of cyclooxygenase inhibitors in aging- and scopolamine or lipopolysaccharide-induced cognitive dysfunction in mice.

  Behavioural brain research 20020718

• Enantiomeric resolution of 2-aryl propionic esters with hyperthermophilic and mesophilic esterases: contrasting thermodynamic mechanisms.

  Journal of the American Chemical Society 20020717

• Preparation of nanosized drug particles by the coating of inorganic cores: naproxen and ketoprofen on alumina.

  Journal of colloid and interface science 20020715

• Enantioselective hydrolysis of naproxen ethyl ester catalyzed by monoclonal antibodies.

  Bioorganic & medicinal chemistry 20020701

• Valdecoxib does not impair platelet function.

  The American journal of emergency medicine 20020701

• Transcutaneous electrical nerve stimulation for pain management in patients with uncomplicated minor rib fractures.

  European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20020701

• Comparison of rofecoxib, celecoxib, and naproxen on renal function in elderly subjects receiving a normal-salt diet.

  Clinical pharmacology and therapeutics 20020701

• Chemical reactivity of the naproxen acyl glucuronide and the naproxen coenzyme A thioester towards bionucleophiles.

  Journal of pharmaceutical and biomedical analysis 20020620

• Spectrofluorometric determination of naproxen in tablets.

  Journal of pharmaceutical and biomedical analysis 20020620

• Juvenile idiopathic arthritis with pulmonary hemosiderosis: a case report.

  Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 20020601

• Randomized placebo-controlled trial comparing efficacy and safety of valdecoxib with naproxen in patients with osteoarthritis.

  The Journal of family practice 20020601

• Right ballpark, wrong base: assessing safety of NSAIDs.

  The Journal of family practice 20020601

• Case 1: Naproxen-induced pseudoporphyria.

  Clinical and experimental dermatology 20020601

• Selective COX-2 Inhibitors, NSAIDs, aspirin, and myocardial infarction.

  Archives of internal medicine 20020527

• Nonsteroidal anti-inflammatory drug use and acute myocardial infarction.

  Archives of internal medicine 20020527

• Lower risk of thromboembolic cardiovascular events with naproxen among patients with rheumatoid arthritis.

  Archives of internal medicine 20020527

• Association between naproxen use and protection against acute myocardial infarction.

  Archives of internal medicine 20020527

• Stereospecific pH-dependent degradation kinetics of R- and S-naproxen-beta-l-O-acyl-glucuronide.

  Chirality 20020505

• Modulation of NSAID-induced antinociceptive and anti-inflammatory effects by alpha2-adrenoceptor agonists with gastroprotective effects.

  Life sciences 20020503

• Awareness and use of over-the-counter pain medications: a survey of emergency department patients.

  Southern medical journal 20020501

• Trends in medication use for osteoarthritis treatment.

  The Journal of rheumatology 20020501

• Topical naproxen sodium for inhibition of miosis during cataract surgery. Prospective, randomized clinical trials.

  Eye (London, England) 20020501

• Effect of inflammatory mediators on the physiology of the human Fallopian tube.

  Human fertility (Cambridge, England) 20020501

• Characterization, quantification, and bioactivities of anthocyanins in Cornus species.

  Journal of agricultural and food chemistry 20020424

• Why do COX-2 inhibitors increase risk of cardiovascular events?

  Lancet (London, England) 20020420

• Biomedicine. Back to an aspirin a day?

  Science (New York, N.Y.) 20020419

• Nonsteroidal drugs and Alzheimer's disease.

  The New England journal of medicine 20020411

• Prostaglandin biosynthesis by midgut tissue isolated from the tobacco hornworm, Manduca sexta.

  Insect biochemistry and molecular biology 20020401

• Polymorphic variants (CYP2C9*3 and CYP2C9*5) and the F114L active site mutation of CYP2C9: effect on atypical kinetic metabolism profiles.

  Drug metabolism and disposition: the biological fate of chemicals 20020401

• An in-vivo study on placental transfer of naproxen in early human pregnancy.

  Human reproduction (Oxford, England) 20020401

• Efficacy and safety of the COX-2 specific inhibitor valdecoxib in the management of osteoarthritis of the hip: a randomized, double-blind, placebo-controlled comparison with naproxen.

  Osteoarthritis and cartilage 20020401

• Platelet function is inhibited by non-selective non-steroidal anti-inflammatory drugs but not by cyclo-oxygenase-2-selective inhibitors in patients with rheumatoid arthritis.

  Rheumatology (Oxford, England) 20020401

• Non-steroidal anti-inflammatory drugs inhibit epinephrine- and cAMP-mediated lipolysis in isolated rat adipocytes.

  The Journal of pharmacy and pharmacology 20020401

• A randomized, double-blind, multicenter trial of nimesulide-beta-cyclodextrin versus naproxen in patients with osteoarthritis.

  Clinical therapeutics 20020401

• Bioactivity of alkamides isolated from Echinacea purpurea (L.) Moench.

  Phytomedicine : international journal of phytotherapy and phytopharmacology 20020401

• Plasticizer effect and comparative evaluation of cellulose acetate and ethylcellulose-HPMC combination coatings as semipermeable membranes for oral osmotic pumps of naproxen sodium.

  Drug development and industrial pharmacy 20020401

• Adverse cutaneous reaction to naproxen: a missed diagnosis fortuitously resolved.

  International journal of clinical practice 20020301

• Conjugation of desmethylnaproxen in the rat--a novel acyl glucuronide-sulfate diconjugate as a major biliary metabolite.

  Drug metabolism and disposition: the biological fate of chemicals 20020201

• Interaction of naproxen with noncrystalline acetyl beta- and acetyl gamma-cyclodextrins in the solid and liquid state.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020201

• Prostaglandin biosynthesis by fat body from larvae of the beetle Zophobas atratus.

  Archives of insect biochemistry and physiology 20020201

• Naproxen ophthalmic solution to manage inflammation after phacoemulsification.

  Journal of cataract and refractive surgery 20020201

• [Long-term prophylaxis with omeprazol is superior to eradication therapy in H. pylori-positive NSAIDs taking patients].

  Zeitschrift fur Gastroenterologie 20020201

• Selective cyclooxygenase-2 inhibitors: after the smoke has cleared.

  Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20020201

• [Prophylaxis against non-steroidal anti-inflammatory drug-associated ulcers and erosions].

  Nihon rinsho. Japanese journal of clinical medicine 20020201

• Peculiar unilateral fixed drug eruption of the breast.

  International journal of dermatology 20020201

• Osteoid osteoma in a young child: successful non-operative management.

  ANZ journal of surgery 20020201

• Non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease: an observational cohort study.

  Lancet (London, England) 20020112

• Three new vanadyl(IV) complexes with non-steroidal anti-inflammatory drugs (Ibuprofen, Naproxen and Tolmetin). Bioactivity on osteoblast-like cells in culture.

  Journal of inorganic biochemistry 20020101

• Mechanism for further enhancement in drug dissolution from solid-dispersion granules upon storage.

  Pharmaceutical development and technology 20020101

• NSAID gastric ulceration: predictive value of gastric pH, mucosal density of polymorphonuclear leukocytes, or levels of IL-8 or nitrite.

  Digestive diseases and sciences 20020101

• Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2).

  Journal of molecular graphics & modelling 20020101

• Influence of irradiation sterilization on poly(lactide-co-glycolide) microspheres containing anti-inflammatory drugs.

  Farmaco (Societa chimica italiana : 1989) 20020101

• Controlled-release naproxen using micronized ethyl cellulose by wet-granulation and solid-dispersion method.

  Drug development and industrial pharmacy 20020101

• [Bullae, erosions and scars in the face of 2 girls with idiopathic arthritis. Naproxen-induced pseudoporphyria].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20020101

• Leukonychia following high altitude exposure.

  High altitude medicine & biology 20020101

• Chondroitin sulfate in erosive osteoarthritis of the hands.

  International journal of tissue reactions 20020101

• Efficacy and tolerability profile of etoricoxib in patients with osteoarthritis: A randomized, double-blind, placebo and active-comparator controlled 12-week efficacy trial.

  Current medical research and opinion 20020101

• A multinational randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis [ISRCTN25142273].

  BMC family practice 20020101

• Effect of combined chemotherapy and anti-inflammatory drugs on murine schistosomiasis.

  Arzneimittel-Forschung 20020101

• Rofecoxib for the treatment of rheumatoid arthritis.

  The Cochrane database of systematic reviews 20020101

• Developing an economic rationale for the use of selective COX-2 inhibitors for patients at risk for NSAID gastropathy.

  Cleveland Clinic journal of medicine 20020101

• Kinetics and hydrolysis mechanism of polymeric prodrugs containing ibuprofen, ketoprofen, and naproxen as pendent agents.

  Journal of biomaterials science. Polymer edition 20020101

• Rofecoxib for the treatment of rheumatoid arthritis.

  The Cochrane database of systematic reviews 20020101

• Naproxen ion-selective electrode and its application to pharmaceutical analysis.

  Acta poloniae pharmaceutica 20020101

• A placebo and active comparator-controlled trial of rofecoxib for the treatment of rheumatoid arthritis.

  Scandinavian journal of rheumatology 20020101

• Pathogenic importance of intestinal hypermotility in NSAID-induced small intestinal damage in rats.

  Digestion 20020101

• Multicentric reticulohistiocytosis in a 14-year-old girl.

  Pediatric dermatology 20020101

• Comparison of low-dose rofecoxib versus 1000 mg naproxen in patients with osteoarthritis. Results of two randomized treatment trials of six weeks duration.

  Scandinavian journal of rheumatology 20020101

• A selective COX-2 inhibitor, meloxicam, as a treatment option in patients with juvenile idiopathic arthritis and gastrointestinal side effects from naproxen.

  Clinical and experimental rheumatology 20020101

• [Colonic stenosis secondary to non-steroid anti-inflammatory agents as a cause of anemia and chronic diarrhea].

  Revista de gastroenterologia de Mexico 20020101

• Ulcers, Helicobacter pylori infection, platelets and gastrointestinal complications of non-steroidal anti-inflammatory drugs: what are the connections?

  The European journal of surgery. Supplement. : = Acta chirurgica. Supplement 20020101

• Activation of peroxisome proliferator-activated receptor isoforms and inhibition of prostaglandin H(2) synthases by ibuprofen, naproxen, and indomethacin.

  Biochemical pharmacology 20011215

• Cyclooxygenase-2 blockade does not impair endothelial vasodilator function in healthy volunteers: randomized evaluation of rofecoxib versus naproxen on endothelium-dependent vasodilatation.

  Circulation 20011211

• Physical characterization of naproxen sodium hydrate and anhydrate forms.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20011201

• Hypersensitivity reactions associated with exposure to naproxen and ibuprofen: a cohort study.

  Journal of clinical epidemiology 20011201

• Acquired Brown's syndrome in a child with poststreptococcal reactive arthritis.

  The Journal of rheumatology 20011201

• Gastrointestinal safety of COX-2 specific inhibitors.

  Gastroenterology clinics of North America 20011201

• Comparison of the efficacy and safety of naproxen CR and nabumetone in the treatment of patients with osteoarthritis of the knee.

  International journal of clinical pharmacology and therapeutics 20011201

• Occurrence of pharmaceutical contaminants and screening of treatment alternatives for southeastern Louisiana.

  Annals of the New York Academy of Sciences 20011201

• Design and evaluation of osmotic pump tablets of naproxen sodium.

  Die Pharmazie 20011201

• Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.

  Chemical communications (Cambridge, England) 20011121

• Cardiovascular thrombotic events in controlled, clinical trials of rofecoxib.

  Circulation 20011106

• Acute gastrointestinal permeability responses to different non-steroidal anti-inflammatory drugs.

  Gut 20011101

• [Naproxen-induced pseudoporphyria].

  Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20011101

• Fulminant necrotizing fasciitis and nonsteroidal anti-inflammatory drugs.

  Intensive care medicine 20011101

• [Renal tolerance of selective inhibitors of cyclooxygenase type 2].

  Presse medicale (Paris, France : 1983) 20011020

• Influence of betacyclodextrin on the release of poorly soluble drugs from inert and hydrophilic heterogeneous polymeric matrices.

  Biomaterials 20011001

• HPLC/1H NMR spectroscopic studies of the reactive alpha-1-O-acyl isomer formed during acyl migration of S-naproxen beta-1-O-acyl glucuronide.

  Chemical research in toxicology 20011001

• Nonsteroidal anti-inflammatory drugs for perioperative pain control.

  Medicine and health, Rhode Island 20011001

• Double-blind study comparing the long-term efficacy of the COX-2 inhibitor nimesulide and naproxen in patients with osteoarthritis.

  International journal of clinical practice 20011001

• Tegumental alterations in Schistosoma mansoni worms induced by treatment of infected mice with naproxen pre- and/or post-infection.

  Arzneimittel-Forschung 20011001

• Effect of water-soluble polymers on naproxen complexation with natural and chemically modified beta-cyclodextrins.

  Drug development and industrial pharmacy 20011001

• Lipopolysaccharide-mediated immobility in mice: reversal by cyclooxygenase enzyme inhibitors.

  Methods and findings in experimental and clinical pharmacology 20011001

• In vitro and in vivo evaluation of polyoxyethylene esters as dermal prodrugs of ketoprofen, naproxen and diclofenac.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010901

• High-performance liquid chromatography determination of bis(monoacylglycerol) phosphate and other lysophospholipids.

  Analytical biochemistry 20010901

• Eosinophilic pustular folliculitis treated with naproxen.

  The British journal of dermatology 20010901

• Non-steroidal anti-inflammatory drugs in the treatment of hyper-IgD syndrome.

  Annals of the rheumatic diseases 20010901

• Upper gastrointestinal safety evaluation of parecoxib sodium, a new parenteral cyclooxygenase-2-specific inhibitor, compared with ketorolac, naproxen, and placebo.

  Clinical therapeutics 20010901

• Dexamethasone decreases migraine recurrence observed after treatment with a triptan combined with a nonsteroidal anti-inflammatory drug.

  Arquivos de neuro-psiquiatria 20010901

• pH-Metric log K calculations of famotidine, naproxen, nizatidine, ranitidine and salicylic acid.

  Farmaco (Societa chimica italiana : 1989) 20010901

• Cyclooxygenase selectivity of non-steroid anti-inflammatory drugs in humans: ex vivo evaluation.

  European journal of pharmacology 20010824

• Palladium-catalyzed alpha-arylation of esters.

  Journal of the American Chemical Society 20010822

• Localization of cyclooxygenase isozymes in cardiovascular tissues of dogs treated with naproxen.

  Veterinary immunology and immunopathology 20010810

• I'm taking over-the-counter ibuprofen every day for neck pain. Recently, my doctor gave me a prescription for naproxen for my arthritis. Should I be concerned about taking these two together?

  Mayo Clinic health letter (English ed.) 20010801

• Nonsteroidal anti-inflammatory therapy after eccentric exercise in healthy older individuals.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20010801

• Osteoid osteoma in a young child: successful non-operative management.

  ANZ journal of surgery 20010801

• Binding constant determination of drugs toward subdomain IIIA of human serum albumin by near-infrared dye-displacement capillary electrophoresis.

  Electrophoresis 20010801

• Synthesis and pharmacological activities of some new 2-[1-(6-methoxy-2-naphthyl)ethyl]-6-(substituted)benzylidene thiazolo[3,2-b]-1,2,4-triazole-5(6H)-one derivatives.

  Die Pharmazie 20010801

• [Safety of specific cyclo-oxygenase 2 inhibitors].

  Nederlands tijdschrift voor geneeskunde 20010728

• Enantiomeric separation of R,S-naproxen by conventional and nano-liquid chromatography with methyl-beta-cyclodextrin as a mobile phase additive.

  Journal of chromatography. A 20010727

• Determination of apparent binding constants of drugs by capillary electrophoresis using beta-cyclodextrin as ligand and three different linear plotting methods.

  Journal of chromatography. A 20010727

• Determination of ibuprofen and naproxen in tablets.

  Journal of pharmaceutical and biomedical analysis 20010701

• Enantioselective inhibition of the binding of rac-profens to human serum albumin induced by lithocholate.

  Chirality 20010701

• Addition of hydrogen bond donating excipients to oil solution: effect on in vitro drug release rate and viscosity.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010701

• Dapsone activation of CYP2C9-mediated metabolism: evidence for activation of multiple substrates and a two-site model.

  Drug metabolism and disposition: the biological fate of chemicals 20010701

• Effects of non-steroidal antiinflammatory drugs and dexamethasone on the activity and expression of matrix metalloproteinase-1, matrix metalloproteinase-3 and tissue inhibitor of metalloproteinases-1 by bovine articular chondrocytes.

  Osteoarthritis and cartilage 20010701

• A possible mechanism of naproxen-induced lipid peroxidation in rat liver microsomes.

  Pharmacology & toxicology 20010701

• Immune thrombocytopenia resulting from sensitivity to metabolites of naproxen and acetaminophen.

  Blood 20010615

• Inhibition of tendon cell proliferation and matrix glycosaminoglycan synthesis by non-steroidal anti-inflammatory drugs in vitro.

  Journal of hand surgery (Edinburgh, Scotland) 20010601

• Treatment of de Quervain's disease:role of conservative management.

  Journal of hand surgery (Edinburgh, Scotland) 20010601

• Fixed drug eruption due to naproxen; lack of cross-reactivity with other propionic acid derivatives.

  The British journal of dermatology 20010601

• By the way, doctor. Which drugs cause problems in the sun?

  Harvard women's health watch 20010601

• Determination of naproxen in pharmaceutical preparations by room-temperature phosphorescence. A comparative study of several organized media.

  The Analyst 20010601

• Disposition of naproxen, naproxen acyl glucuronide and its rearrangement isomers in the isolated perfused rat liver.

  Xenobiotica; the fate of foreign compounds in biological systems 20010601

• Effect of hydroxypropyl methylcellulose and hydrogenated castor oil on naproxen release from sustained-release tablets.

  AAPS PharmSciTech 20010601

• Stereoselective synthesis of (S)-(+)-Naproxen catalyzed by carboxyl esterase in a multicompartment electrolyzer.

  Journal of biochemical and biophysical methods 20010528

• Isotachophoretic determination of naproxen in the presence of its metabolite in human serum.

  Journal of chromatography. A 20010504

• Upper gastrointestinal toxicity of rofecoxib and naproxen.

  The New England journal of medicine 20010503

• Upper gastrointestinal toxicity of rofecoxib and naproxen.

  The New England journal of medicine 20010503

• The influence of polyvinylpyrrolidone on naproxen complexation with hydroxypropyl-beta-cyclodextrin.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010501

• Severe reversible renal failure due to naproxen-associated acute interstitial nephritis.

  European journal of pediatrics 20010501

• [The selective Cox-2 inhibition by rofecoxib reduces risk of severe gastrointestinal complications of anti-inflammatory therapy by more than 50%].

  Zeitschrift fur Gastroenterologie 20010501

• Synthesis, in vitro skin permeation studies, and PLS-analysis of new naproxen derivatives.

  Pharmaceutical research 20010501

• [Acupuncture contra antiphlogistics in acute lumbago].

  Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20010420

• Uniformly sized molecularly imprinted polymer for (S)-naproxen retention and molecular recognition properties in aqueous mobile phase.

  Journal of chromatography. A 20010413

• S-naproxen-beta-1-O-acyl glucuronide degradation kinetic studies by stopped-flow high-performance liquid chromatography-1H NMR and high-performance liquid chromatography-UV.

  Drug metabolism and disposition: the biological fate of chemicals 20010401

• Pharmacokinetic/pharmacodynamic modeling of antipyretic and anti-inflammatory effects of naproxen in the rat.

  The Journal of pharmacology and experimental therapeutics 20010401

• Risk of ulcer soars with combination of arthritis drugs.

  The Western journal of medicine 20010401

• Endogenous prostaglandin E2 and insulin-like growth factor 1 can modulate the levels of parathyroid hormone receptor in human osteoarthritic osteoblasts.

  Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010401

• Reduced incidence of gastroduodenal ulcers with celecoxib, a novel cyclooxygenase-2 inhibitor, compared to naproxen in patients with arthritis.

  The American journal of gastroenterology 20010401

• Naproxen-Eudragit microspheres: screening of process and formulation variables for the preparation of extended release tablets.

  Die Pharmazie 20010401

• Naproxen particle design using porous starch.

  Drug development and industrial pharmacy 20010401

• Celecoxib in osteoarthritis and rheumatoid arthritis: new preparation. As disappointing as rofecoxib.

  Prescrire international 20010401

• Preventing recurrent upper gastrointestinal bleeding in patients with Helicobacter pylori infection who are taking low-dose aspirin or naproxen.

  The New England journal of medicine 20010329

• Prostaglandin biosynthesis by fat body from true armyworms, Pseudaletia unipuncta.

  Insect biochemistry and molecular biology 20010315

• Selective inhibition of COX-2 in humans is associated with less gastrointestinal injury: a comparison of nimesulide and naproxen.

  Gut 20010301

• Effect of antipyretic drugs in children with malaria.

  Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010301

• Analysis of nonsteroidal antiinflammatory drugs in meconium and its relation to persistent pulmonary hypertension of the newborn.

  Pediatrics 20010301

• Rofecoxib, a COX-2 inhibitor, does not inhibit human gastric mucosal prostaglandin production.

  Gastroenterology 20010301

• Is rofecoxib safer than naproxen?

  The Journal of family practice 20010301

• Functional status and health-related quality of life of elderly osteoarthritic patients treated with celecoxib.

  The journals of gerontology. Series A, Biological sciences and medical sciences 20010301

• Neuroprotective effects of non-steroidal anti-inflammatory drugs by direct scavenging of nitric oxide radicals.

  Journal of neurochemistry 20010301

• Pharmacokinetics, safety, and tolerability of BAY 12-9566 and nonsteroidal anti-inflammatory agents (naproxen, ibuprofen) during coadministration in patients with osteoarthritis.

  Journal of clinical pharmacology 20010301

• High-performance liquid chromatographic method development and validation for the simultaneous quantitation of naproxen sodium and pseudoephedrine hydrochloride impurities.

  Journal of chromatographic science 20010301

• Anti-lymphoma effect of naproxen and indomethacin in a patient with relapsed diffuse large B-cell lymphoma.

  American journal of hematology 20010301

• Acute postoperative swelling after hand surgery: an exploratory, double-blind, randomised study with paracetamol, naproxen, and placebo.

  Scandinavian journal of plastic and reconstructive surgery and hand surgery 20010301

• Interleukin-6 (IL-6) producing phaeochromocytoma: direct IL-6 suppression by non-steroidal anti-inflammatory drugs.

  Clinical endocrinology 20010301

• Peroxisomal proliferator-activated ligand therapy for HIV lipodystrophy.

  Clinical and experimental dermatology 20010301

• Synthesis and cyclooxygenase inhibitory properties of novel (+) 2-(6-methoxy-2-naphthyl)propanoic acid (naproxene) derivatives.

  Archiv der Pharmazie 20010301

• [Chronic recurrent multifocal osteomyelitis].

  Anales espanoles de pediatria 20010201

• A look at the safety profile of over-the-counter naproxen sodium: a meta-analysis.

  Journal of clinical pharmacology 20010201

• Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen.

  Journal of pharmaceutical and biomedical analysis 20010201

• Alendronate and naproxen are synergistic for development of gastric ulcers.

  Archives of internal medicine 20010108

• Randomized trial of low-dose misoprostol and naproxen vs. nabumetone to prevent recurrent upper gastrointestinal haemorrhage in users of non-steroidal anti-inflammatory drugs.

  Alimentary pharmacology & therapeutics 20010101

• Successful use of propranolol in migraine associated with electroconvulsive therapy.

  Headache 20010101

• Isolated tuberculous monoarthritis mimicking oligoarticular juvenile rheumatoid arthritis.

  The Journal of rheumatology 20010101

• Efficacy of single-dose and multidose rofecoxib in the treatment of post-orthopedic surgery pain.

  American journal of orthopedics (Belle Mead, N.J.) 20010101

• LC-1H NMR used for determination of the elution order of S-naproxen glucuronide isomers in two isocratic reversed-phase LC-systems.

  Journal of pharmaceutical and biomedical analysis 20010101

• Rhein, an active metabolite of diacerein, suppresses the interleukin-1alpha-induced proteoglycan degradation in cultured rabbit articular chondrocytes.

  Japanese journal of pharmacology 20010101

• Naproxen availability from variable-dose and weight sustained-release tablets.

  Drug development and industrial pharmacy 20010101

• [Drug-induced aphthae].

  Annales de dermatologie et de venereologie 20010101

• Nimesulide, a balanced drug for the treatment of osteoarthritis.

  Clinical and experimental rheumatology 20010101

• Differential regulation of interleukin-1 beta-induced cyclooxygenase-2 gene expression by nimesulide in human synovial fibroblasts.

  Clinical and experimental rheumatology 20010101

• In vitro evaluation and intra-articular administration of biodegradable microspheres containing naproxen sodium.

  Journal of microencapsulation 20010101

• [Two complex suicidal poisonings with drugs and their medicolegal aspects].

  Przeglad lekarski 20010101

• Nonsteroidal anti-inflammatory drugs in early pregnancy.

  Reproductive toxicology (Elmsford, N.Y.) 20010101

• Response surface methodology to obtain naproxen controlled release tablets from its microspheres with Eudragit L100-55.

  Journal of microencapsulation 20010101

• [Effect of naproxen on serum concentrations of IL-I, IL-6, and TNF in patients with osteoarthritis].

  Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20010101

• Pharmacokinetic and pharmacodynamic aspects of the ideal COX-2 inhibitor: a rheumatologist's perspective.

  Clinical and experimental rheumatology 20010101

• The role of anti-inflammatory drugs in the treatment of osteoarthritis: a European viewpoint.

  Clinical and experimental rheumatology 20010101

• Clinical investigation of methotrexate in the treatment of ankylosing spondylitis.

  Scandinavian journal of rheumatology 20010101

• Influence of pump compliance (peristaltic vs. infusion) on urodynamic measurement during cystometry in conscious rats.

  Journal of pharmacological and toxicological methods 20010101

• [Effects of paracetamol and naproxen on pain syndromes of various genesis].

  Eksperimental'naia i klinicheskaia farmakologiia 20010101

• Comparative efficacy and safety of celecoxib and naproxen in the treatment of osteoarthritis of the hip.

  The Journal of international medical research 20010101

• Clinical evaluation of the effective use of magnetic fields in podology.

  La Chirurgia degli organi di movimento 20010101

• Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis. VIGOR Study Group.

  The New England journal of medicine 20001123

• [Aspirin-induced angioedema of the nape of the neck with naproxen cross-reaction: a case report].

  Annales de medecine interne 20000501

• Naproxen-induced leukocytoclastic vasculitis.

  Clinical rheumatology 20000101

• Persistent pulmonary hypertension after maternal naproxen ingestion in a term newborn: a case report.

  American journal of perinatology 20000101

• Long-term followup of naproxen-induced pseudoporphyria in juvenile rheumatoid arthritis.

  Arthritis and rheumatism 19991001

• Low-dose diclofenac, naproxen, and ibuprofen cohort study.

  Pharmacotherapy 19990701

• Renal changes associated with naproxen sodium administration in cynomolgus monkeys.

  Toxicologic pathology 19990101

• Naproxen-associated sudden sensorineural hearing loss.

  Military medicine 19981101

• [Pain therapy after tonsillectomy in adults].

  HNO 19980101

• Effect of a nitric oxide-releasing naproxen derivative on hypertension and gastric damage induced by chronic nitric oxide inhibition in the rat.

  Life sciences 19980101

• Nonsteroidal anti-inflammatory drugs as scaffolds for the design of 5-lipoxygenase inhibitors.

  Journal of medicinal chemistry 19970227

• Serum protein binding of nonsteroidal antiinflammatory drugs: a comparative study.

  Journal of pharmacokinetics and biopharmaceutics 19970201

• [Leukocytoclastic vasculitis associated with naproxen].

  Harefuah 19960501

• Tepoxalin blocks neutrophil migration into cutaneous inflammatory sites by inhibiting Mac-1 and E-selectin expression.

  European journal of immunology 19960101

• Exacerbation of idiopathic Parkinson's disease by naproxen.

  BMJ (Clinical research ed.) 19950812

• Suppression of NF kappa B activation and NF kappa B-dependent gene expression by tepoxalin, a dual inhibitor of cyclooxygenase and 5-lipoxygenase.

  Journal of cellular biochemistry 19950201

• Renal impairment after acute diclofenac, naproxen, and sulindac overdoses.

  Journal of toxicology. Clinical toxicology 19950101

• LTB4-induced transient neutropenia in the rat: a model for evaluating efficacy and bioavailability of LTB4 receptor antagonists.

  Journal of pharmacological and toxicological methods 19931101

• Reinduction of the hypnotic effects of thiopental with NSAIDs by decreasing thiopental plasma protein binding in humans.

  Acta anaesthesiologica Scandinavica 19930401

• [Daily chronic headache in patients with migraine induced by abuse of ergotamine-analgesics: response due to a protocol of outpatient treatment].

  Neurologia (Barcelona, Spain) 19930101

• Nonsteroidal antiinflammatory drugs and certain rare, serious adverse events: a cohort study.

  Pharmacotherapy 19930101

• Naproxen-associated vasculitis.

  Postgraduate medical journal 19920901

• Reversible bone marrow aplasia induced by naproxen.

  Annals of hematology 19920701

• [Vasculitic skin lesions caused by nonsteroidal anti-inflammatory agents].

  Schweizerische medizinische Wochenschrift 19920613

• A study of betel quid carcinogenesis--VIII. Carcinogenicity of 3-(methylnitrosamino)propionaldehyde in F344 rats.

  Carcinogenesis 19920301

• The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis.

  European journal of clinical pharmacology 19920101

• Naproxen-induced recurrent aseptic meningitis.

  DICP : the annals of pharmacotherapy 19911101

• Abrupt outpatient withdrawal of medication in analgesic-abusing migraineurs.

  Lancet (London, England) 19910615

• Progression of a naproxen and amoxicillin induced acute interstitial nephritis with nephrotic syndrome: case report.

  Clinical nephrology 19910501

• Neurological adverse effects of naproxen and misoprostol combination.

  The British journal of general practice : the journal of the Royal College of General Practitioners 19901001

• Effects of sulindac and naproxen on prostaglandin excretion in patients with impaired renal function and rheumatoid arthritis.

  The American journal of medicine 19900901

• Acute interstitial nephritis with nephrotic syndrome after intake of naproxen and amoxycillin.

  Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19900101

• Naproxen-induced nephropathy in systemic lupus erythematosus.

  Nephron 19900101

• Naproxen-associated fatal acute renal failure in multiple myeloma.

  Nephron 19900101

• Naproxen reversal of nortriptyline-induced orthostatic hypotension.

  The Journal of clinical psychiatry 19890901

• Hypersensitivity angiitis associated with naproxen.

  Annals of allergy 19890801

• [Acute anemia, rectorrhagia and hematuria caused by ingestion of naproxen].

  Anales espanoles de pediatria 19890401

• Two double blind trials of diclofenac sodium with aspirin and with naproxen in the treatment of patients with rheumatoid arthritis.

  The Journal of rheumatology 19880801

• Hyperkalemia induced by indomethacin and naproxen and reversed by fludrocortisone.

  Southern medical journal 19880601

• Naproxen nephrotoxicity in a 2-year-old child.

  American journal of diseases of children (1960) 19880501

• Aseptic meningitis associated with naproxen.

  Drug intelligence & clinical pharmacy 19880501

• Naproxen-associated renal failure in a child with arthritis and inflammatory bowel disease.

  Pediatrics 19871201

• Multiple myeloma in naproxen-induced acute renal failure.

  The New England journal of medicine 19870716

• Amelioration of ergotamine withdrawal symptoms with naproxen.

  Headache 19870301

• Drug-induced peripheral neuropathy in a patient with psoriatic arthritis.

  Arthritis and rheumatism 19870201

• Spontaneous relapse of naproxen-related nephrotic syndrome.

  The American journal of medicine 19870201

• Pulmonary oedema, jaundice and renal impairment with naproxen.

  British journal of rheumatology 19870201

• Piroxicam in acute musculoskeletal disorders and sport injuries.

  European journal of rheumatology and inflammation 19870101

• Naproxen and acute renal failure in a runner.

  Annals of internal medicine 19860701

• Acute renal failure associated with acute pyelonephritis and consumption of non-steroidal anti-inflammatory drugs.

  British medical journal (Clinical research ed.) 19860111

• A double-blind multicentre trial of piroxicam and naproxen in osteoarthritis.

  Clinical rheumatology 19860101

• Acute reversible renal failure following naproxen (naxyn) administration.

  Scandinavian journal of rheumatology 19860101

• Nephrotoxicity from nonsteroidal anti-inflammatory drugs.

  Southern medical journal 19850301

• Comparison of a slow-release indomethacin tablet and naproxen in osteoarthrosis.

  Current medical research and opinion 19850101

• Renal papillary necrosis due to naproxen.

  The Journal of rheumatology 19840201

• Nabumetone, a new non-steroidal anti-inflammatory drug: a comparison with naproxen.

  The New Zealand medical journal 19831214

• Hemolytic anemia associated with naproxen.

  Arthritis and rheumatism 19830801

• Antrafenine, naproxen and placebo in osteoarthritis: a comparative study.

  British journal of rheumatology 19830501

• A double blind study of antrafenine, naproxen and placebo in osteoarthrosis.

  European journal of rheumatology and inflammation 19830101

• Concurrent naproxen- and penicillamine-induced renal disease in rheumatoid arthritis.

  Arthritis and rheumatism 19820801

• Renal papillary necrosis following regular consumption of non-steroidal anti-inflammatory drugs.

  The New Zealand medical journal 19820414

• Naproxen and sudden hearing loss.

  The Journal of laryngology and otology 19820201

• Possible naproxen-associated vasculitis.

  Archives of internal medicine 19800701

• Aplastic anaemia after naproxen?

  Lancet (London, England) 19800209

• A comparison of naproxen, indomethacin and aspirin in osteoarthritis.

  The Journal of rheumatology 19800101

• Reversible renal failure and nephrotic syndrome associated with nonsteroidal anti-inflammatory drugs.

  The New England journal of medicine 19791206

• Persistent pulmonary hypertension and abnormal prostaglandin E levels in preterm infants after maternal treatment with naproxen.

  Archives of disease in childhood 19791201

• Vasculitis in a patient receiving naproxen.

  The New Zealand medical journal 19790124

• Naproxen vs. aspirin in osteoarthritis of the hip and knee.

  The Journal of rheumatology 19780101

• [Clinical results of a multicentral double-blind examination of naproxen compared to indomethacin in chronic rheumatoid arthritis, ankylosing spondylitis, and osteoarthrosis].

  Arzneimittel-Forschung 19750201