2620-62-4 | N6,N6-Dimethyladenosine

Packsize	Purity	Availability	Price	Discounted Price
250mg	95%	in stock	$89.00	$62.00
500mg	95%	in stock	$170.00	$119.00
1g	95%	in stock	$233.00	$163.00
5g	95%	in stock	$789.00	$553.00

Description

• Catalog Number: AF30239
• Chemical Name: N6,N6-Dimethyladenosine
• CAS Number: 2620-62-4
• Molecular Formula: C12H17N5O4
• Molecular Weight: 295.2945
• MDL Number: MFCD00022822
• SMILES: OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N(C)C

Computed Properties

• Complexity: 374
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 4
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 8
• Hydrogen Bond Donor Count: 3
• Rotatable Bond Count: 3
• XLogP3: -0.2

Literature

• Control of substrate specificity by a single active site residue of the KsgA methyltransferase.

  Biochemistry 20120110

• Atomic mutagenesis reveals A2660 of 23S ribosomal RNA as key to EF-G GTPase activation.

  Nature chemical biology 20100501

• Synthesis of pyrrolo[2,3-d]pyrimidine nucleoside derivatives as potential anti-HCV agents.

  Bioorganic chemistry 20070201

• Analogs of 3'-amino-3'-deoxyadenosine inhibit HIV-1 replication.

  AIDS research and human retroviruses 19891201

• Ribosome structure: localization of N6,N6-dimethyladenosine by electron microscopy of a ribosome-antibody complex.

  Proceedings of the National Academy of Sciences of the United States of America 19770401