263707-16-0 | 3-Isoxazolepropanenitrile, α-[2-(3-chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-β-oxo-

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$15.00	$11.00
5mg	98%	in stock	$37.00	$26.00
10mg	98%	in stock	$56.00	$39.00

Description

• Catalog Number: AB30596
• Chemical Name: 3-Isoxazolepropanenitrile, α-[2-(3-chlorophenyl)hydrazinylidene]-5-(1,1-dimethylethyl)-β-oxo-
• CAS Number: 263707-16-0
• Molecular Formula: C16H15ClN4O2
• Molecular Weight: 330.7689
• MDL Number: MFCD00109218
• SMILES: N#CC(=NNc1cccc(c1)Cl)C(=O)c1noc(c1)C(C)(C)C

Computed Properties

• Complexity: 520
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 23
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 5
• XLogP3: 5.2

Literature

• Role of Exchange Protein Directly Activated by Cyclic AMP Isoform 1 in Energy Homeostasis: Regulation of Leptin Expression and Secretion in White Adipose Tissue.

  Molecular and cellular biology 20161001

• Recent advances in the discovery of small molecules targeting exchange proteins directly activated by cAMP (EPAC).

  Journal of medicinal chemistry 20140508

• Exchange protein directly activated by cAMP plays a critical role in bacterial invasion during fatal rickettsioses.

  Proceedings of the National Academy of Sciences of the United States of America 20131126

• A novel EPAC-specific inhibitor suppresses pancreatic cancer cell migration and invasion.

  Molecular pharmacology 20130101

• [Differences in the responses of taste receptors to organic and inorganic acids with changes in the concentration of bicarbonate in the solution].

  Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova 19750601