26386-86-7 | 3-Hydroxyquinolin-2-one

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$293.00	$205.00
250mg	95%	in stock	$465.00	$325.00
1g	95%	in stock	$1,148.00	$804.00
5g	95%	in stock	$3,418.00	$2,393.00

Description

• Catalog Number: AB30676
• Chemical Name: 3-Hydroxyquinolin-2-one
• CAS Number: 26386-86-7
• Molecular Formula: C9H7NO2
• Molecular Weight: 161.1574
• MDL Number: MFCD08705722
• SMILES: O=c1[nH]c2ccccc2cc1O

Computed Properties

• Complexity: 235
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• XLogP3: 1.2

Literature

• Metabolism and pharmacokinetics of indacaterol in humans.

  Drug metabolism and disposition: the biological fate of chemicals 20120901

• Development of a series of 3-hydroxyquinolin-2(1H)-ones as selective inhibitors of HIV-1 reverse transcriptase associated RNase H activity.

  Bioorganic & medicinal chemistry letters 20120615

• Recurrent very late stent thrombosis in a systemic lupus erythematous patient.

  Korean circulation journal 20120201

• 3-Hy-droxy-4-(3-hy-droxy-phen-yl)-2-quinolone monohydrate.

  Acta crystallographica. Section E, Structure reports online 20110801

• Iron specificity of a biosensor based on fluorescent pyoverdin immobilized in sol-gel glass.

  Journal of biological engineering 20110101

• Characterization of pyoverdine and achromobactin in Pseudomonas syringae pv. phaseolicola 1448a.

  BMC microbiology 20110101

• Synthesis of the siderophore pyoverdine in Pseudomonas aeruginosa involves a periplasmic maturation.

  Amino acids 20100501

• The Therapeutic Potential of D-Amino Acid Oxidase (DAAO) Inhibitors.

  The open medicinal chemistry journal 20100101

• Discovery, SAR, and pharmacokinetics of a novel 3-hydroxyquinolin-2(1H)-one series of potent D-amino acid oxidase (DAAO) inhibitors.

  Journal of medicinal chemistry 20090611

• Emerging role of integrase inhibitors in the management of treatment-experienced patients with HIV infection.

  Therapeutics and clinical risk management 20090101

• A liquid chromatography-quadrupole time-of-flight (LC-QTOF)-based metabolomic approach reveals new metabolic effects of catechin in rats fed high-fat diets.

  Journal of proteome research 20080601

• Genomic, genetic and structural analysis of pyoverdine-mediated iron acquisition in the plant growth-promoting bacterium Pseudomonas fluorescens SBW25.

  BMC microbiology 20080101

• Mixed-valence Cu(II)/Cu(I) complex of quinolone ciprofloxacin isolated by a hydrothermal reaction in the presence of L-histidine: comparison of biological activities of various copper-ciprofloxacin compounds.

  Journal of inorganic biochemistry 20050201

• Novel tandem hydration/cyclodehydration of alpha-thiocyanatoketones to 2-oxo-3-thiazolines. Application to thiazolo[5,4-c]quinoline-2,4(3aH,5H)-dione synthesis.

  The Journal of organic chemistry 20040820

• Genomics of pyoverdine-mediated iron uptake in pseudomonads.

  Trends in microbiology 20030501

• Identification and characterization of novel pyoverdine synthesis genes in Pseudomonas aeruginosa.

  Microbiology (Reading, England) 20030401

• A siderophore peptide synthetase gene from plant-growth-promoting Pseudomonas putida WCS358.

  Systematic and applied microbiology 20011101