269067-38-1 | Fmoc-cys(mtt)-oh

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$27.00	$19.00
5g	97%	in stock	$68.00	$48.00
25g	97%	in stock	$235.00	$165.00

Description

• Catalog Number: AF65665
• Chemical Name: Fmoc-cys(mtt)-oh
• CAS Number: 269067-38-1
• Molecular Formula: C38H33NO4S
• Molecular Weight: 599.7379
• MDL Number: MFCD02259492
• SMILES: Cc1ccc(cc1)C(c1ccccc1)(c1ccccc1)SC[C@@H](C(=O)O)NC(=O)OCC1c2ccccc2c2c1cccc2

Computed Properties

• Complexity: 897
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 44
• Hydrogen Bond Acceptor Count: 5
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 11
• XLogP3: 8.4

Upstream Synthesis Route

Fmoc-Cys(Mtt)-OH is a crucial building block in chemical synthesis, particularly in the field of peptide synthesis. This compound consists of a cysteine amino acid with a 9-fluorenylmethoxycarbonyl (Fmoc) protecting group and a methyltrityl (Mtt) protecting group attached to the thiol (-SH) group of cysteine.The Fmoc group is commonly used in solid-phase peptide synthesis to protect the N-terminal amine of amino acids, allowing for selective deprotection and chain elongation. The Mtt group, on the other hand, serves to protect the thiol group of cysteine, preventing unwanted side reactions during peptide assembly. Overall, Fmoc-Cys(Mtt)-OH facilitates the controlled and efficient synthesis of cysteine-containing peptides, enabling chemists to perform sequential coupling reactions with other amino acids while ensuring the preservation of the cysteine residue until the desired stage of the synthesis. Its application in chemical synthesis contributes to the synthesis of complex peptides with high purity and yield.