274-85-1 | [1,2,4]Triazolo[1,5-a]pyridine

Packsize	Purity	Availability	Price	Discounted Price
250mg	97%	in stock	$28.00	$20.00
1g	97%	in stock	$49.00	$34.00
5g	97%	in stock	$175.00	$123.00

Description

• Catalog Number: AF65303
• Chemical Name: [1,2,4]Triazolo[1,5-a]pyridine
• CAS Number: 274-85-1
• Molecular Formula: C6H5N3
• Molecular Weight: 119.124
• MDL Number: MFCD03700708
• SMILES: c1ccc2n(c1)ncn2
• NSC Number: 99874

Computed Properties

• Complexity: 105
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 2
• XLogP3: 0.7

Literature

• A selective, orally bioavailable 1,2,4-triazolo[1,5-a]pyridine-based inhibitor of Janus kinase 2 for use in anticancer therapy: discovery of CEP-33779.

  Journal of medicinal chemistry 20120614

• Novel 1,2,4-triazolo[1,5-a]pyridines and their fused ring systems attenuate oxidative stress and prolong lifespan of Caenorhabiditis elegans.

  Journal of medicinal chemistry 20120510

• Rearrangement of aryl- and benzylthiopyridinium imides with participation of a methyl substituent.

  The Journal of organic chemistry 20111118

• DNA gyrase (GyrB)/topoisomerase IV (ParE) inhibitors: synthesis and antibacterial activity.

  Bioorganic & medicinal chemistry letters 20090201