27427-92-5 | 2-Pyrimidinecarboxaldehyde

Packsize	Purity	Availability	Price	Discounted Price
100mg	98%	in stock	$33.00	$24.00
250mg	98%	in stock	$42.00	$30.00
1g	98%	in stock	$123.00	$87.00
5g	98%	in stock	$331.00	$232.00
10g	98%	in stock	$553.00	$388.00
25g	98%	in stock	$1,108.00	$776.00

Description

• Catalog Number: AB52254
• Chemical Name: 2-Pyrimidinecarboxaldehyde
• CAS Number: 27427-92-5
• Molecular Formula: C5H4N2O
• Molecular Weight: 108.0981
• MDL Number: MFCD07778416
• SMILES: O=Cc1ncccn1

Computed Properties

• Complexity: 78.5
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1

Upstream Synthesis Route

2-Pyrimidinecarboxaldehyde is a versatile compound widely used in chemical synthesis as a key building block for the production of various pharmaceuticals, agrochemicals, and other fine chemicals. It serves as a valuable intermediate in the synthesis of heterocyclic compounds due to its unique structural properties and reactivity. Due to the presence of the pyrimidine ring, 2-Pyrimidinecarboxaldehyde offers a range of opportunities for functional group transformations and diversification, making it a valuable starting material for the construction of complex molecular structures. It can undergo a variety of chemical reactions such as nucleophilic additions, condensations, and redox processes to introduce different substituents and functionalities at specific positions within the molecule.In pharmaceutical syntheses, 2-Pyrimidinecarboxaldehyde is often employed in the preparation of bioactive molecules, including anti-cancer drugs, anti-viral agents, and central nervous system drugs. Its use in agrochemical synthesis enables the creation of novel pesticides, herbicides, and plant growth regulators. Furthermore, in material science, 2-Pyrimidinecarboxaldehyde can be utilized to develop advanced materials with tailored properties for various applications.Overall, the versatile nature of 2-Pyrimidinecarboxaldehyde makes it an essential component in the toolkit of synthetic chemists, enabling the efficient and precise construction of a wide range of valuable compounds with diverse applications.

Literature

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  PloS one 20110101

• Trigonal bi- and monopyramidal cobalt(II) complexes of a novel guanidine-based tripodal ligand.

  Inorganic chemistry 20101220

• Structure and kinetic investigation of Streptococcus pyogenes family GH38 alpha-mannosidase.

  PloS one 20100101

• Formation of a chiral center and pyrimidal inversion at the single-molecule level.

  Angewandte Chemie (International ed. in English) 20070101

• [Effect of coriaria lactone on the activation of Ca(2+)-activated K+ channel in hippocampal pyrimidal neurons of rats].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20040101

• [Effect of coriaria lactone on the ATP-sensitive potassium channels in pyrimidal neurons of rats].

  Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20031001

• The culture of chick forebrain neurons.

  Methods in cell biology 20030101