2743-90-0 | (R,S)-Anatabine

Packsize	Purity	Availability	Price	Discounted Price
5mg	95%	in stock	$48.00	$34.00
100mg	95%	in stock	$74.00	$52.00
250mg	95%	in stock	$124.00	$87.00
1g	95%	in stock	$355.00	$248.00
5g	95%	in stock	$1,224.00	$857.00

Description

• Catalog Number: AF29081
• Chemical Name: (R,S)-Anatabine
• CAS Number: 2743-90-0
• Molecular Formula: C10H12N2
• Molecular Weight: 160.21568
• MDL Number: MFCD00078278
• SMILES: C1=CCC(NC1)c1cccnc1

Computed Properties

• Complexity: 165
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• Undefined Atom Stereocenter Count: 1
• XLogP3: 0.9

Literature

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• Parent quit attempts after counseling to reduce children's secondhand smoke exposure and promote cessation: main and moderating relationships.

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• Silencing of PMT expression caused a surge of anatabine accumulation in tobacco.

  Molecular biology reports 20091101

• The addition of five minor tobacco alkaloids increases nicotine-induced hyperactivity, sensitization and intravenous self-administration in rats.

  The international journal of neuropsychopharmacology 20091101

• Validation of a GC-FID method for rapid quantification of nicotine in fermented extracts prepared from Nicotiana tabacum fresh leaves and studies of nicotine metabolites.

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• The A622 gene in Nicotiana glauca (tree tobacco): evidence for a functional role in pyridine alkaloid synthesis.

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• Determination of nicotine, cotinine, and related alkaloids in human urine and saliva by automated in-tube solid-phase microextraction coupled with liquid chromatography-mass spectrometry.

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• Enantioseparation of nicotine alkaloids in cigarettes by CE using sulfated beta-CD as a chiral selector and a capillary coated with amino groups.

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• Nicotine content and delivery across tobacco products.

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• Why does anatabine, but not nicotine, accumulate in jasmonate-elicited cultured tobacco BY-2 cells?

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• Enantiomeric analysis of anatabine, nornicotine and anabasine in commercial tobacco by multi-dimensional gas chromatography and mass spectrometry.

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• Antisense-mediated reduction in ADC activity causes minor alterations in the alkaloid profile of cultured hairy roots and regenerated transgenic plants of Nicotiana tabacum.

  Phytochemistry 20071001

• Analyses of tobacco alkaloids by cation-selective exhaustive injection sweeping microemulsion electrokinetic chromatography.

  Journal of chromatography. A 20070914

• Characterisation of nicotine and related compounds using electrospray ionisation with ion trap mass spectrometry and with quadrupole time-of-flight mass spectrometry and their detection by liquid chromatography/electrospray ionisation mass spectrometry.

  Rapid communications in mass spectrometry : RCM 20070101

• Acute and subacute effects of tobacco alkaloids, tobacco-specific nitrosamines and phenethyl isothiocyanate on N'-nitrosonornicotine metabolism in rats.

  Toxicology 20051115

• A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine.

  The AAPS journal 20050901

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• A comparison of urinary biomarkers of tobacco and carcinogen exposure in smokers.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20041001

• Anatalline and other methyl jasmonate-inducible nicotine alkaloids from Nicotiana tabacum cv. By-2 cell cultures.

  Planta medica 20041001

• Nicotine's defensive function in nature.

  PLoS biology 20040801

• Nicotine-related alkaloids and metabolites as inhibitors of human cytochrome P-450 2A6.

  Biochemical pharmacology 20040215

• Effects of reduced cigarette smoking on the uptake of a tobacco-specific lung carcinogen.

  Journal of the National Cancer Institute 20040121

• Fast analysis of nicotine related alkaloids in tobacco and cigarette smoke by megabore capillary gas chromatography.

  Journal of chromatography. A 20031031

• Antisense-mediated down-regulation of putrescine N-methyltransferase activity in transgenic Nicotiana tabacum L. can lead to elevated levels of anatabine at the expense of nicotine.

  Plant molecular biology 20030901

• Anabasine and anatabine as biomarkers for tobacco use during nicotine replacement therapy.

  Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20021201

• Determination of nicotine and other minor alkaloids in international cigarettes by solid-phase microextraction and gas chromatography/mass spectrometry.

  Analytical chemistry 20021001

• Determination of tobacco alkaloids by gas chromatography with nitrogen-phosphorus detection.

  Analytical and bioanalytical chemistry 20020401

• Comparison of methods for extraction of tobacco alkaloids.

  Journal of AOAC International 20010101