27527-05-5 | (S)-(+)-Cyclohexylalanine

Packsize	Purity	Availability	Price	Discounted Price
1g	97%	in stock	$10.00	$7.00
5g	95%	in stock	$14.00	$10.00
10g	95%	in stock	$17.00	$12.00
25g	95%	in stock	$41.00	$29.00
500g	97%	in stock	$495.00	$347.00

Description

• Catalog Number: AB31996
• Chemical Name: (S)-(+)-Cyclohexylalanine
• CAS Number: 27527-05-5
• Molecular Formula: C9H17NO2
• Molecular Weight: 171.2368
• MDL Number: MFCD03703498
• SMILES: N[C@H](C(=O)O)CC1CCCCC1

Computed Properties

• Complexity: 153
• Covalently-Bonded Unit Count: 1
• Defined Atom Stereocenter Count: 1
• Heavy Atom Count: 12
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 3
• XLogP3: -0.3

Literature

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  Chemistry (Weinheim an der Bergstrasse, Germany) 20120507

• Probing phenylalanine environments in oligomeric structures with pentafluorophenylalanine and cyclohexylalanine.

  Biopolymers 20110601

• Deletion of Ac-NMePhe(1) from [NMePhe(1) ]arodyn under acidic conditions, part 2: effects of substitutions on pharmacological activity.

  Biopolymers 20110101

• Design of glycopeptides used to investigate class II MHC binding and T-cell responses associated with autoimmune arthritis.

  PloS one 20110101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Demonstration of a peroxide shunt in the tetrahydropterin-dependent aromatic amino acid monooxygenases.

  Journal of the American Chemical Society 20090408

• Quantum dots for live cell and in vivo imaging.

  International journal of molecular sciences 20090201

• Development of inhibitors against lipase and alpha-glucosidase from derivatives of monascus pigment.

  FEMS microbiology letters 20071101

• Expression levels of adenosine receptors in hippocampus and frontal cortex in argyrophilic grain disease.

  Neuroscience letters 20070823

• Beta-methyl substitution of cyclohexylalanine in Dmt-Tic-Cha-Phe peptides results in highly potent delta opioid antagonists.

  Journal of medicinal chemistry 20070125

• Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels.

  Bioorganic & medicinal chemistry letters 20060301

• Tuning wasp toxin structure for nicotinic receptor antagonism: cyclohexylalanine-containing analogues as potent and voltage-dependent blockers.

  ChemMedChem 20060301

• Up-regulation of adenosine A1 receptor binding in pentylenetetrazol kindling in mice: effects of angiotensin IV.

  Brain research 20050125

• Strand orientation by steric matching: a designed antiparallel coiled-coil trimer.

  Journal of the American Chemical Society 20041110

• Investigation of the nature of the methionine-pi interaction in beta-hairpin peptide model systems.

  Protein science : a publication of the Protein Society 20040901

• Comparison of C-H...pi and hydrophobic interactions in a beta-hairpin peptide: impact on stability and specificity.

  Journal of the American Chemical Society 20040225

• Sequential and specific exchange of multiple coiled-coil components.

  Journal of the American Chemical Society 20031029

• Specific control of peptide assembly with combined hydrophilic and hydrophobic interfaces.

  Journal of the American Chemical Society 20030122

• Peptide tic-tac-toe: heterotrimeric coiled-coil specificity from steric matching of multiple hydrophobic side chains.

  Journal of the American Chemical Society 20020821

• The methyl group of N(alpha)(Me)Arg-containing peptides disturbs the active-site geometry of thrombin, impairing efficient cleavage.

  Journal of molecular biology 20020301

• Mapping the ligand-binding site on the C5a receptor: arginine74 of C5a contacts aspartate282 of the C5a receptor.

  Biochemistry 20011120

• Coiled-coil formation governed by unnatural hydrophobic core side chains.

  Journal of the American Chemical Society 20011107