2756-85-6 | 1-Aminocyclohexanecarboxylic acid

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$12.00	$9.00
10g	98%	in stock	$22.00	$16.00
100g	98%	in stock	$219.00	$153.00
250g	98%	in stock	$451.00	$316.00

Description

• Catalog Number: AB32081
• Chemical Name: 1-Aminocyclohexanecarboxylic acid
• CAS Number: 2756-85-6
• Molecular Formula: C7H13NO2
• Molecular Weight: 143.1836
• MDL Number: MFCD00001487
• SMILES: OC(=O)C1(N)CCCCC1
• NSC Number: 9059

Computed Properties

• Complexity: 139
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 10
• Hydrogen Bond Acceptor Count: 3
• Hydrogen Bond Donor Count: 2
• Rotatable Bond Count: 1
• XLogP3: -1.9

Literature

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  Biochimica et biophysica acta 20110101

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• Drug design, in vitro pharmacology, and structure-activity relationships of 3-acylamino-2-aminopropionic acid derivatives, a novel class of partial agonists at the glycine site on the N-methyl-D-aspartate (NMDA) receptor complex.

  Journal of medicinal chemistry 20090827

• Redetermination of 1-carboxy-cyclo-hexan-1-aminium chloride.

  Acta crystallographica. Section E, Structure reports online 20090201

• Synthesis and utilization of chiral alpha-methylated alpha-amino acids with a carboxyalkyl side chain in the design of novel Grb2-SH2 peptide inhibitors free of phosphotyrosine.

  Journal of medicinal chemistry 20081023

• cis-3-(tert-Butoxy-carbonyl-amino)cyclo-hexa-necarboxylic acid.

  Acta crystallographica. Section E, Structure reports online 20080901

• Application of 1-aminocyclohexane carboxylic acid to protein nanostructure computer design.

  Journal of chemical information and modeling 20080201

• An expanded set of amino acid analogs for the ribosomal translation of unnatural peptides.

  PloS one 20070101

• New bradykinin analogues substituted in positions 7 and 8 with sterically restricted 1-aminocyclopentane-1-carboxylic acid.

  Journal of peptide science : an official publication of the European Peptide Society 20061201

• Application of azide-alkyne cycloaddition 'click chemistry' for the synthesis of Grb2 SH2 domain-binding macrocycles.

  Bioorganic & medicinal chemistry letters 20061015

• Raman and surface-enhanced Raman spectroscopy investigation of vasopressin analogues containing 1-aminocyclohexane-1-carboxylic acid residue.

  Biopolymers 20061005

• New bradykinin analogues modified in the C-terminal part with sterically restricted 1-aminocyclohexane-1-carboxylic acid.

  Journal of medicinal chemistry 20051215

• Design and synthesis of tri-ring P3 benzamide-containing aminonitriles as potent, selective, orally effective inhibitors of cathepsin K.

  Journal of medicinal chemistry 20051201

• The influence of 1-aminocyclopentane-1-carboxylic acid at position 2 or 3 of AVP and its analogues on their pharmacological properties.

  Journal of peptide science : an official publication of the European Peptide Society 20050901

• Design and synthesis of conformationally constrained Grb2 SH2 domain binding peptides employing alpha-methylphenylalanyl based phosphotyrosyl mimetics.

  Journal of medicinal chemistry 20050210

• Bioactive N-terminal undecapeptides derived from parathyroid hormone: the role of alpha-helicity.

  The journal of peptide research : official journal of the American Peptide Society 20050101

• Highly potent 1-aminocyclohexane-1-carboxylic acid substituted V2 agonists of arginine vasopressin.

  Journal of medicinal chemistry 20041118

• Influence of 1-aminocyclohexane-1-carboxylic acid in position 2 or 3 of AVP and its analogues on their pharmacological properties.

  The journal of peptide research : official journal of the American Peptide Society 20030801

• The structure of an endomorphin analogue incorporating 1-aminocyclohexane-1-carboxlylic acid for proline is similar to the beta-turn of Leu-enkephalin.

  Biochemical and biophysical research communications 20020913

• Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

  The Journal of biological chemistry 20020419

• Nitroxyl peptides as catalysts of enantioselective oxidations.

  Chemistry (Weinheim an der Bergstrasse, Germany) 20020104

• Amphipathic control of the 3(10)-/alpha-helix equilibrium in synthetic peptides.

  The journal of peptide research : official journal of the American Peptide Society 20010801

• Chloramine-T in radiolabeling techniques. IV. Penta-O-acetyl-N-chloro-N-methylglucamine as an oxidizing agent in radiolabelling techniques.

  Analytical biochemistry 20010101

• Crystal-state conformation of Calpha,alpha-dialkylated peptides containing chiral beta-homo-residues.

  Journal of peptide science : an official publication of the European Peptide Society 20010101