2756-87-8 | Monomethyl fumarate

Packsize	Purity	Availability	Price	Discounted Price
5g	98%	in stock	$8.00	$5.00
25g	98%	in stock	$10.00	$7.00
100g	98%	in stock	$12.00	$8.00
500g	98%	in stock	$46.00	$32.00

Description

• Catalog Number: AB32080
• Chemical Name: Monomethyl fumarate
• CAS Number: 2756-87-8
• Molecular Formula: C5H6O4
• Molecular Weight: 130.0987
• MDL Number: MFCD00063174
• SMILES: COC(=O)/C=C/C(=O)O

Computed Properties

• Complexity: 147
• Covalently-Bonded Unit Count: 1
• Defined Bond Stereocenter Count: 1
• Heavy Atom Count: 9
• Hydrogen Bond Acceptor Count: 4
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 3
• XLogP3: 0.4

Literature

• Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).

  Bioorganic & medicinal chemistry letters 20110501

• Carbonic anhydrase inhibitors. Identification of selective inhibitors of the human mitochondrial isozymes VA and VB over the cytosolic isozymes I and II from a natural product-based phenolic library.

  Bioorganic & medicinal chemistry 20100101

• The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist.

  Biochemical and biophysical research communications 20081031

• [Modulatory effect of fumaric acid esters on superoxide-anion generation in human phagocytes].

  Yao xue xue bao = Acta pharmaceutica Sinica 20071101

• Dimethylfumarate inhibits nuclear binding of nuclear factor kappaB but not of nuclear factor of activated T cells and CCAAT/enhancer binding protein beta in activated human T cells.

  The British journal of dermatology 20070501

• Reactivity of dimethyl fumarate and methylhydrogen fumarate towards glutathione and N-acetyl-L-cysteine--preparation of S-substituted thiosuccinic acid esters.

  Bioorganic & medicinal chemistry 20070101

• Fumaric acid esters are effective in chronic experimental autoimmune encephalomyelitis and suppress macrophage infiltration.

  Clinical and experimental immunology 20060701

• Enhancement of antibacterial superoxide-anion generation in human monocytes by fumaric acid esters.

  Archives of dermatological research 20051001