27992-32-1 | 6-Bromopyridin-2-ol

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$10.00	$7.00
5g	98%	in stock	$12.00	$9.00
10g	98%	in stock	$15.00	$11.00
25g	98%	in stock	$34.00	$24.00
100g	98%	in stock	$95.00	$67.00

Description

• Catalog Number: AB61473
• Chemical Name: 6-Bromopyridin-2-ol
• CAS Number: 27992-32-1
• Molecular Formula: C5H4BrNO
• Molecular Weight: 173.9954
• MDL Number: MFCD00234043
• SMILES: Oc1cccc(n1)Br

Computed Properties

• Complexity: 171
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• XLogP3: 1.1

Upstream Synthesis Route

The upstream synthesis route of 6-Bromopyridin-2-ol typically begins with 2-Hydroxypyridine as the starting material. The following steps are involved:

1. Bromination: React 2-Hydroxypyridine with bromine (Br2) in an appropriate solvent like chloroform (CHCl3) at 0°C to low temperature. This step selectively adds a bromine atom at the 6-position due to the electron-rich nature of the pyridine ring resulting from the hydroxy group at the 2-position.

2. Purification: Purify the resultant 6-Bromopyridin-2-ol using column chromatography or recrystallization, depending on the scale of synthesis and purity requirements.

Analytical techniques such as NMR, GC-MS, or HPLC can be used to verify the structure and purity of the synthesized 6-Bromopyridin-2-ol.