280-05-7 | 8-Azabicyclo[3.2.1]octane hydrochloride

Packsize	Purity	Availability	Price	Discounted Price
100mg	95%	in stock	$203.00	$142.00
250mg	95%	in stock	$299.00	$209.00
1g	95%	in stock	$713.00	$499.00
5g	95%	in stock	$2,625.00	$1,837.00

Description

• Catalog Number: AF36023
• Chemical Name: 8-Azabicyclo[3.2.1]octane hydrochloride
• CAS Number: 280-05-7
• Molecular Formula: C7H13N
• Molecular Weight: 111.1848
• MDL Number: MFCD13196389
• SMILES: C1CC2CCC(C1)N2

Computed Properties

• Complexity: 80.4
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 8
• Hydrogen Bond Acceptor Count: 1
• Hydrogen Bond Donor Count: 1
• Undefined Atom Stereocenter Count: 2
• XLogP3: 1.3

Literature

• Asymmetric synthesis of the tropane alkaloid (+)-pseudococaine via ring-closing iodoamination.

  Organic letters 20120817

• Epoxide opening-induced tandem 8-azabicyclo[3.2.1]octane to 6-azabicyclo[3.2.1]octane rearrangement-iminium allylation: synthesis of (+/-)-peduncularine.

  Organic letters 20100618

• 3D-QSAR study of 8-azabicyclo[3.2.1] octane analogs antagonists of cholinergic receptor.

  Bioorganic & medicinal chemistry letters 20090601

• Thermal elimination of diethyldithiocarbamates and application in the synthesis of (+/-)-ferrugine.

  The Journal of organic chemistry 20081017

• Photoreactions of bicyclic aziridines with alkenes and alkynes: a novel synthetic methodology for 8-azabicyclo[3.2.1]octane derivatives.

  Organic & biomolecular chemistry 20080907

• Preparation of a library of unsymmetrical ureas based on 8-azabicyclo[3.2.1]octane scaffold.

  Journal of combinatorial chemistry 20080101

• Discovery of novel 8-azoniabicyclo[3.2.1]octane carbamates as muscarinic acetylcholine receptor antagonists.

  Bioorganic & medicinal chemistry letters 20071115

• Quaternary derivatives of granatanol diesters: potent, ultrashort acting non-depolarizing neuromuscular relaxants.

  Life sciences 20060704

• Synthetic approaches to enantiomerically pure 8-azabicyclo[3.2.1]octane derivatives.

  Chemical reviews 20060601

• Synthesis and nicotinic acetylcholine receptor binding affinities of 2- and 3-isoxazolyl-8-azabicyclo[3.2.1]octanes.

  Bioorganic & medicinal chemistry letters 20040405

• Cycloadditions of 2-azaallyllithium species with conjugated polyenes.

  The Journal of organic chemistry 20040220

• Modulation of selective serotonin reuptake inhibitor and 5-HT1A antagonist activity in 8-aza-bicyclo[3.2.1]octane derivatives of 2,3-dihydro-1,4-benzodioxane.

  Bioorganic & medicinal chemistry letters 20040119

• Synthesis of bridged azabicyclic structures via ring-closing olefin metathesis.

  The Journal of organic chemistry 20031114

• Synthesis and nicotinic binding studies on enantiopure pinnamine variants with an 8-azabicyclo[3.2.1]octane moiety.

  Die Pharmazie 20030501

• Stereoselective syntheses of (+/-)-epibatidine analogues.

  Archives of pharmacal research 20020201

• Syntheses of (+/-)-homoepibatidine analogues.

  Archives of pharmacal research 20020201