284028-89-3 | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$20.00	$14.00
5mg	98%	in stock	$44.00	$31.00
10mg	98%	in stock	$84.00	$59.00
25mg	98%	in stock	$122.00	$85.00
50mg	98%	in stock	$235.00	$164.00
100mg	98%	in stock	$338.00	$237.00
250mg	98%	in stock	$649.00	$454.00

Description

• Catalog Number: AB51978
• Chemical Name: 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one
• CAS Number: 284028-89-3
• Molecular Formula: C14H11F3N2OS
• Molecular Weight: 312.3101
• MDL Number: MFCD16879017
• SMILES: O=c1nc([nH]c2c1CSCC2)c1ccc(cc1)C(F)(F)F

Computed Properties

• Complexity: 505
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 21
• Hydrogen Bond Acceptor Count: 6
• Hydrogen Bond Donor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 2.3

Literature

• WNT7A/β-catenin signaling induces FGF1 and influences sensitivity to niclosamide in ovarian cancer.

  Oncogene 20150601

• Combination effects of AHR agonists and Wnt/β-catenin modulators in zebrafish embryos: Implications for physiological and toxicological AHR functions.

  Toxicology and applied pharmacology 20150415

• Inhibition of canonical WNT signaling attenuates human leiomyoma cell growth.

  Fertility and sterility 20140501

• Biological significance and therapeutic implication of resveratrol-inhibited Wnt, Notch and STAT3 signaling in cervical cancer cells.

  Genes & cancer 20140501

• 2,3,7,8-Tetrachlorodibenzo-p-dioxin stimulates proliferation of HAPI microglia by affecting the Akt/GSK-3β/cyclin D1 signaling pathway.

  Toxicology letters 20140130

• Novel binding mode of a potent and selective tankyrase inhibitor.

  PloS one 20120101