28466-26-4 | 4-Amino-1H-pyrazole

Packsize	Purity	Availability	Price	Discounted Price
1g	95%	in stock	$13.00	$9.00
5g	95%	in stock	$22.00	$16.00
10g	95%	in stock	$39.00	$28.00
25g	95%	in stock	$96.00	$68.00

Description

• Catalog Number: AB33759
• Chemical Name: 4-Amino-1H-pyrazole
• CAS Number: 28466-26-4
• Molecular Formula: C3H5N3
• Molecular Weight: 83.0919
• MDL Number: MFCD01693729
• SMILES: Nc1c[nH]nc1

Computed Properties

• Complexity: 45.3
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 2
• Hydrogen Bond Donor Count: 2
• XLogP3: -1.1

Upstream Synthesis Route

1H-Pyrazol-4-amine, also known as 4-Amino-1H-pyrazole, is a versatile building block in chemical synthesis due to its unique structure and reactivity. This compound serves as a key intermediate in the preparation of various pharmaceuticals, agrochemicals, and functional materials. In synthetic organic chemistry, 1H-Pyrazol-4-amine is frequently utilized in the construction of heterocyclic compounds through condensation reactions with aldehydes, ketones, and carboxylic acids. Additionally, it can undergo substitution reactions to introduce different functional groups, further expanding its synthetic utility. With its diverse applications and broad scope in chemical synthesis, 1H-Pyrazol-4-amine is an indispensable tool for researchers and chemists seeking to access novel molecular structures and complex molecules.

Literature

• 2-Aminothiophenes as building blocks in heterocyclic synthesis: synthesis and antimicrobial evaluation of a new class of pyrido[1,2-a]thieno[3,2-e]pyrimidine, quinoline and pyridin-2-one derivatives.

  European journal of medicinal chemistry 20120601

• Acylation of heteroaromatic amines: facile and efficient synthesis of a new class of 1,2,3-triazolo[4,5-b]pyridine and pyrazolo[4,3-b]pyridine derivatives.

  Molecules (Basel, Switzerland) 20110504

• Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol.

  BMC biochemistry 20070101