2854-32-2 | Ethanone, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl)-

Packsize	Purity	Availability	Price	Discounted Price
1mg	98%	in stock	$20.00	$14.00
5mg	98%	in stock	$34.00	$24.00
10mg	98%	in stock	$55.00	$38.00
25mg	98%	in stock	$78.00	$54.00
50mg	98%	in stock	$116.00	$81.00
100mg	98%	in stock	$178.00	$124.00
250mg	98%	in stock	$272.00	$190.00

Description

• Catalog Number: AB34149
• Chemical Name: Ethanone, 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]-1-(4-morpholinyl)-
• CAS Number: 2854-32-2
• Molecular Formula: C23H23ClN2O4
• Molecular Weight: 426.8927
• MDL Number: MFCD01317813
• SMILES: COc1ccc2c(c1)c(CC(=O)N1CCOCC1)c(n2C(=O)c1ccc(cc1)Cl)C

Computed Properties

• Complexity: 618
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 30
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• XLogP3: 3.8

Literature

• Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

  Bioorganic & medicinal chemistry letters 20101101

• In vitro metabolism of indomethacin morpholinylamide (BML-190), an inverse agonist for the peripheral cannabinoid receptor (CB(2)) in rat liver microsomes.

  European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100911

• Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

  Nature chemical biology 20091001

• BML-111, a lipoxin receptor agonist, modulates the immune response and reduces the severity of collagen-induced arthritis.

  Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20080401

• Cannabinoids stimulate fibroblastic colony formation by bone marrow cells indirectly via CB2 receptors.

  Calcified tissue international 20070101

• Reduction of human monocytic cell neurotoxicity and cytokine secretion by ligands of the cannabinoid-type CB2 receptor.

  British journal of pharmacology 20030601

• BML-190 and AM251 act as inverse agonists at the human cannabinoid CB2 receptor: signalling via cAMP and inositol phosphates.

  FEBS letters 20030211