28860-25-5 | N-Ethyl-n-methylformamide

Packsize	Purity	Availability	Price	Discounted Price
1g	98%	in stock	$26.00	$18.00
5g	98%	in stock	$44.00	$31.00
25g	98%	in stock	$90.00	$63.00
100g	98%	in stock	$275.00	$193.00
500g	98%	in stock	$914.00	$640.00

Description

• Catalog Number: AB35730
• Chemical Name: N-Ethyl-n-methylformamide
• CAS Number: 28860-25-5
• Molecular Formula: C4H9NO
• Molecular Weight: 87.1204
• MDL Number: MFCD21103047
• SMILES: CN(C=O)CC
• NSC Number: 514424

Computed Properties

• Complexity: 44.8
• Covalently-Bonded Unit Count: 1
• Heavy Atom Count: 6
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• XLogP3: 0.1

Upstream Synthesis Route

N-Ethyl-N-methylformamide, also known as N,N-dimethylacetamide (DMA), is a versatile solvent commonly used in chemical synthesis. Its unique properties make it suitable for a variety of applications in organic chemistry. DMA serves as a powerful solvent for a broad range of organic compounds due to its high solubility and low volatility. It is frequently used in reactions involving sensitive reagents or high temperatures, making it an indispensable tool for organic chemists. Additionally, DMA can be employed as a reaction medium in the formation of polymers, pharmaceuticals, and other complex organic molecules. Its high boiling point and stability allow for precise control over reactions, resulting in high yields and purity of products. In summary, N-Ethyl-N-methylformamide plays a crucial role in facilitating various chemical reactions and promoting the synthesis of valuable compounds in the field of organic chemistry.

Literature

• Design and development of thermolytic DNA oligonucleotide prodrugs.

  Annals of the New York Academy of Sciences 20051101

• Conceptual 'Heat-Driven' approach to the synthesis of DNA oligonucleotides on microarrays.

  Annals of the New York Academy of Sciences 20031201

• The 2-(N-formyl-N-methyl)aminoethyl group as a potential phosphate/thiophosphate protecting group in solid-phase oligodeoxyribonucleotide synthesis.

  Organic letters 20010503